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Search Results: 1 - 10 of 148133 matches for " Stefan K Beckers "
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Jahrestagung 2012 in Aachen - Tagungsbericht [GMA Annual Conference 2012 in Aachen - Conference Report]
Simon, Melanie,Sopka, Sasa,Beckers, Stefan K.
GMS Zeitschrift für Medizinische Ausbildung , 2012, DOI: 10.3205/zma000833
Abstract:
Undergraduate medical education in emergency medical care: A nationwide survey at German medical schools
Stefan K Beckers, Arnd Timmermann, Michael P Müller, Matthias Angstwurm, Felix Walcher
BMC Emergency Medicine , 2009, DOI: 10.1186/1471-227x-9-7
Abstract: Using a standardized questionnaire, all medical faculties in Germany were asked to answer questions concerning the structure of their curriculum, representation of disciplines, instructors' qualifications, teaching and assessment methods, as well as evaluation procedures.Data from 35 of the 38 medical schools in Germany were analysed. In 32 of 35 medical faculties, the local Department of Anaesthesiology is responsible for the teaching of emergency medical care; in two faculties, emergency medicine is taught mainly by the Department of Surgery and in another by Internal Medicine. Lectures, seminars and practical training units are scheduled in varying composition at 97% of the locations. Simulation technology is integrated at 60% (n = 21); problem-based learning at 29% (n = 10), e-learning at 3% (n = 1), and internship in ambulance service is mandatory at 11% (n = 4). In terms of assessment methods, multiple-choice exams (15 to 70 questions) are favoured (89%, n = 31), partially supplemented by open questions (31%, n = 11). Some faculties also perform single practical tests (43%, n = 15), objective structured clinical examination (OSCE; 29%, n = 10) or oral examinations (17%, n = 6).Emergency Medical Care in undergraduate medical education in Germany has a practical orientation, but is very inconsistently structured. The innovative options of simulation technology or state-of-the-art assessment methods are not consistently utilized. Therefore, an exchange of experiences and concepts between faculties and disciplines should be promoted to guarantee a standard level of education in emergency medical care.In June 2002, Germany revised nationwide regulations, requiring new subjects such as anaesthesiology or public health as compulsory subjects, or interdisciplinary courses in health economics, ethics or epidemiology within the different local curricula [1]. "Emergency Medical Care" was introduced as an interdisciplinary subject, because issues in emergency treatment ar
Strukturell-organisatorische Entwicklung und Etablierung eines interdisziplin ren Trainingszentrums für klinisch-praktische Fertigkeiten [Structural and organizational development and establishment of an interdisciplinary Skills Lab ]
Beckers, Stefan K.,Sopka, Sasa,Classen-Linke, Irmgard,Weishoff-Houben, Michaela
GMS Zeitschrift für Medizinische Ausbildung , 2010, DOI: 10.3205/zma000647
Abstract: [english] Background: Besides theoretical knowledge, medical students have to acquire different skills during their medical education, which are essential especially for the physician’s routine practice. In July 2005 an interdisciplinary skills lab was set up at the Medical Faculty of the RWTH Aachen University. Financial and personnel resources for the structural and organizational development of the skills lab were obtained first from a faculty fund for innovative teaching concepts, and later from student fees. Methods: Elements of project management necessary for the skills lab were defined in advance: Development of a methodological concept, definition of content and selection of skills, provision of infrastructural necessities (rooms, media, staff), creation of a pilot course concept, definition of milestones, acquisition of powerful faculty partners for further support, implementation of courses within the ongoing curricula, and evaluation of individual courses and the entire concept. Results: The project management steps defined in advance were retrospectively proven necessary and important for the establishment of a minimum infrastructure in terms of spatial and human resources and for the implementation of the methodological concept. During the 2008 summer semester, a total of 709 students in 133 faculty courses and about 900 students in curricular courses used the skills lab. Conclusion: Three years on, the interdisciplinary skills lab offers a wide range of courses in which students can learn, train, and optimize their practical skills. The experiences gained in designing and organizing the program are essential for the further structural and methodological/didactic development of the skills lab. [german] Hintergrund: Neben theoretischem Wissen müssen Medizinstudierende Fertigkeiten unterschiedlichster Art erwerben, die nicht nur für die praktischen Ausbildungsteile im Studium, sondern in erster Linie für das t gliche rztliche Handeln essentiell sind. Im Juli 2005 begann der Aufbau eines interdisziplin ren Trainingszentrums an der medizinischen Fakult t der Rheinisch-Westf lischen Technischen Hochschule Aachen, genannt AIXTRA“ (Aachener interdisziplin res Trainingszentrum für medizinische Ausbildung). Sach- und Personalmittel zur strukturellen und methodischen Etablierung des sog. Skillslab wurden zun chst aus einem fakult tsinternen F rderprogramm für innovative Lehrkonzepte, im weiteren Verlauf zum überwiegenden Teil aus Studienbeitr gen zur Verfügung gestellt. Methodik: Im Vorfeld wurden die folgenden notwendigen Schritte eines Projektman
From Dynamic Expression Patterns to Boundary Formation in the Presomitic Mesoderm
Hendrik B. Tiedemann,Elida Schneltzer,Stefan Zeiser,Bastian Hoesel,Johannes Beckers,Gerhard K. H. Przemeck,Martin Hrabě de Angelis
PLOS Computational Biology , 2012, DOI: 10.1371/journal.pcbi.1002586
Abstract: The segmentation of the vertebrate body is laid down during early embryogenesis. The formation of signaling gradients, the periodic expression of genes of the Notch-, Fgf- and Wnt-pathways and their interplay in the unsegmented presomitic mesoderm (PSM) precedes the rhythmic budding of nascent somites at its anterior end, which later develops into epithelialized structures, the somites. Although many in silico models describing partial aspects of somitogenesis already exist, simulations of a complete causal chain from gene expression in the growth zone via the interaction of multiple cells to segmentation are rare. Here, we present an enhanced gene regulatory network (GRN) for mice in a simulation program that models the growing PSM by many virtual cells and integrates WNT3A and FGF8 gradient formation, periodic gene expression and Delta/Notch signaling. Assuming Hes7 as core of the somitogenesis clock and LFNG as modulator, we postulate a negative feedback of HES7 on Dll1 leading to an oscillating Dll1 expression as seen in vivo. Furthermore, we are able to simulate the experimentally observed wave of activated NOTCH (NICD) as a result of the interactions in the GRN. We esteem our model as robust for a wide range of parameter values with the Hes7 mRNA and protein decays exerting a strong influence on the core oscillator. Moreover, our model predicts interference between Hes1 and HES7 oscillators when their intrinsic frequencies differ. In conclusion, we have built a comprehensive model of somitogenesis with HES7 as core oscillator that is able to reproduce many experimentally observed data in mice.
Evaluation of a newly developed media-supported 4-step approach for basic life support training
Sa?a Sopka, Henning Biermann, Rolf Rossaint, Sebastian Knott, Max Skorning, J?rg C Brokmann, Nicole Heussen, Stefan K Beckers
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine , 2012, DOI: 10.1186/1757-7241-20-37
Abstract: After baseline testing, 220 laypersons were either trained using the widely accepted method for resuscitation training (4-step approach) or using a newly created “media-supported 4-step approach”, both of equal duration. In this approach, steps 1 and 2 were ensured via a standardised self-produced podcast, which included all of the information regarding the BLS algorithm and resuscitation skills. Participants were tested on manikins in the same mock cardiac arrest single-rescuer scenario prior to intervention, after one week and after six months with respect to ECC-performance, and participants were surveyed about the approach.Participants (age 23?±?11, 69% female) reached comparable practical ECC performances in both groups, with no statistical difference. Even after six months, there was no difference detected in the quality of the initial assessment algorithm or delay concerning initiation of CPR. Overall, at least 99% of the intervention group (n?=?99; mean 1.5?±?0.8; 6-point Likert scale: 1?=?completely agree, 6?=?completely disagree) agreed that the video provided an adequate introduction to BLS skills.The “media-supported 4-step approach” leads to comparable practical ECC-performance compared to standard teaching, even with respect to retention of skills. Therefore, this approach could be useful in special educational settings where, for example, instructors’ resources are sparse or large-group sessions have to be prepared.Within cardiopulmonary resuscitation (CPR), external chest compressions (ECC) are the key element providing forward blood flow, thereby maintaining heart and brain viability. Thus, ECC are of primary importance for improving outcomes after in- or out-of-hospital cardiac arrest.Existing data about the ideal training methods for basic life support (BLS) are still insufficient; the duration of BLS training that is adequate remains unknown. Pedagogic training methods are thought to be the best, but specific auxiliary training methods that would
Fast Synchronization of Ultradian Oscillators Controlled by Delta-Notch Signaling with Cis-Inhibition
Hendrik B. Tiedemann,Elida Schneltzer,Stefan Zeiser,Wolfgang Wurst,Johannes Beckers,Gerhard K. H. Przemeck,Martin Hrabě de Angelis
PLOS Computational Biology , 2014, DOI: doi/10.1371/journal.pcbi.1003843
Abstract: While it is known that a large fraction of vertebrate genes are under the control of a gene regulatory network (GRN) forming a clock with circadian periodicity, shorter period oscillatory genes like the Hairy-enhancer-of split (Hes) genes are discussed mostly in connection with the embryonic process of somitogenesis. They form the core of the somitogenesis-clock, which orchestrates the periodic separation of somites from the presomitic mesoderm (PSM). The formation of sharp boundaries between the blocks of many cells works only when the oscillators in the cells forming the boundary are synchronized. It has been shown experimentally that Delta-Notch (D/N) signaling is responsible for this synchronization. This process has to happen rather fast as a cell experiences at most five oscillations from its ‘birth’ to its incorporation into a somite. Computer simulations describing synchronized oscillators with classical modes of D/N-interaction have difficulties to achieve synchronization in an appropriate time. One approach to solving this problem of modeling fast synchronization in the PSM was the consideration of cell movements. Here we show that fast synchronization of Hes-type oscillators can be achieved without cell movements by including D/N cis-inhibition, wherein the mutual interaction of DELTA and NOTCH in the same cell leads to a titration of ligand against receptor so that only one sort of molecule prevails. Consequently, the symmetry between sender and receiver is partially broken and one cell becomes preferentially sender or receiver at a given moment, which leads to faster entrainment of oscillators. Although not yet confirmed by experiment, the proposed mechanism of enhanced synchronization of mesenchymal cells in the PSM would be a new distinct developmental mechanism employing D/N cis-inhibition. Consequently, the way in which Delta-Notch signaling was modeled so far should be carefully reconsidered.
Feasibility of Prehospital Teleconsultation in Acute Stroke – A Pilot Study in Clinical Routine
Sebastian Bergrath, Arno Reich, Rolf Rossaint, Daniel R?rtgen, Joachim Gerber, Harold Fischermann, Stefan K. Beckers, J?rg C. Brokmann, J?rg B. Schulz, Claas Leber, Christina Fitzner, Max Skorning
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0036796
Abstract: Background Inter-hospital teleconsultation improves stroke care. To transfer this concept into the emergency medical service (EMS), the feasibility and effects of prehospital teleconsultation were investigated. Methodology/Principal Findings Teleconsultation enabling audio communication, real-time video streaming, vital data and still picture transmission was conducted between an ambulance and a teleconsultation center. Pre-notification of the hospital was carried out with a 14-item stroke history checklist via e-mail-to-fax. Beside technical assessments possible influences on prehospital and initial in-hospital time intervals, prehospital diagnostic accuracy and the transfer of stroke specific data were investigated by comparing telemedically assisted prehospital care (telemedicine group) with local regular EMS care (control group). All prehospital stroke patients over a 5-month period were included during weekdays (7.30 a.m. –4.00 p.m.). In 3 of 18 missions partial dropouts of the system occurred; neurological co-evaluation via video transmission was conducted in 12 cases. The stroke checklist was transmitted in 14 cases (78%). Telemedicine group (n = 18) vs. control group (n = 47): Prehospital time intervals were comparable, but in both groups the door to brain imaging times were longer than recommended (median 59.5 vs. 57.5 min, p = 0.6447). The prehospital stroke diagnosis was confirmed in 61% vs. 67%, p = 0.8451. Medians of 14 (IQR 9) vs. 5 (IQR 2) stroke specific items were transferred in written form to the in-hospital setting, p<0.0001. In 3 of 10 vs. 5 of 27 patients with cerebral ischemia thrombolytics were administered, p = 0.655. Conclusions Teleconsultation was feasible but technical performance and reliability have to be improved. The approach led to better stroke specific information; however, a superiority over regular EMS care was not found and in-hospital time intervals were unacceptably long in both groups. The feasibility of prehospital tele-stroke consultation has future potential to improve emergency care especially when no highly trained personnel are on-scene. Trial Registration International Standard Randomised Controlled Trial Number Register (ISRCTN) ISRCTN83270177 83270177.
Notfallmedizinische Ausbildung für Studierende der Zahnmedizin: Zwei Pilotprojekte []
Beckers, Stefan,Sopka, Sasa,Gillmann, Benjamin,Knops, Andrea
GMS Zeitschrift für Medizinische Ausbildung , 2008,
Abstract:
Produktion von Lehrmedien im Qualifikationsprofil Neue Medien, Kommunikation, Didaktik in der Medizin“ im Modellstudiengang Humanmedizin Aachen: Ein Aufgabengebiet für die An sthesiologie? []
Beckers, Stefan,Sopka, Sasa,Ohnesorge-Radtke, Ulla,Rossaint, Rolf
GMS Zeitschrift für Medizinische Ausbildung , 2008,
Abstract:
Basis-Reanimation leichter gemacht! Check-Call-Compress []
Skorning, Max,Beckers, Stefan,Brokmann, J?rg,Ellrich, Daniel
GMS Zeitschrift für Medizinische Ausbildung , 2008,
Abstract:
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