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Search Results: 1 - 10 of 45361 matches for " So-Young Jun "
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The associations between socioeconomic status and obesity in Korean children from 1998 to 2009  [PDF]
So-Young Nam, Soo-Kyung Lee
Health (Health) , 2013, DOI: 10.4236/health.2013.511256

Increasing interests have been shown in associations between socioeconomic status (SES) and obesity in relation to health inequality. The research objectives were 1) to examine associations between SES and child obesity (including overweight) in Korea over 10 years and 2) to explore possible underlying mechanisms of relationships between SES and obesity. This study used the nationally representative data (KNHA-NES) from 1998, 2005, to 2009. Children (10-18 year-old) were grouped by household income (low, middle-low, middle-high and high) adjusted for the number of family members. Z-scores of height, weight, and BMI for each child were calculated from measured anthropometric data using the 2007 Korean national growth charts. No statistically significant associations were found, however, changes in association patterns were noted. The lower SES group showed shorter height as well as lighter weight among Korean children. More research should be conducted to understand the effects of socioeconomic status on child obesity.


Membrane Fusion Proteins of Type I Secretion System and Tripartite Efflux Pumps Share a Binding Motif for TolC in Gram-Negative Bacteria
Minho Lee, So-Young Jun, Bo-Young Yoon, Saemee Song, Kangseok Lee, Nam-Chul Ha
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0040460
Abstract: The Hly translocator complex of Escherichia coli catalyzes type I secretion of the toxin hemolysin A (HlyA). In this complex, HlyB is an inner membrane ABC (ATP Binding Cassette)-type transporter, TolC is an outer membrane channel protein, and HlyD is a periplasmic adaptor anchored in the inner membrane that bridges HlyB to TolC. This tripartite organization is reminiscent of that of drug efflux systems such as AcrA-AcrB-TolC and MacA-MacB-TolC of E. coli. We have previously shown the crucial role of conserved residues located at the hairpin tip region of AcrA and MacA adaptors during assembly of their cognate systems. In this study, we investigated the role of the putative tip region of HlyD using HlyD mutants with single amino acid substitutions at the conserved positions. In vivo and in vitro data show that all mutations abolished HlyD binding to TolC and resulted in the absence of HlyA secretion. Together, our results suggest that, similarly to AcrA and MacA, HlyD interacts with TolC in a tip-to-tip manner. A general model in which these conserved interactions induce opening of TolC during drug efflux and type I secretion is discussed.
Acupuncture Treatment of a Patient with Persistent Allergic Rhinitis Complicated by Rhinosinusitis and Asthma
Ae-Ran Kim,Jun-Yong Choi,Jong-In Kim,So-Young Jung,Sun-Mi Choi
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/nep240
Abstract: A pathophysiologic relationship between allergic rhinitis and rhinosinusitis and asthma has long been suggested. However, few clinical studies of acupuncture have been conducted on these comorbid conditions. A 48-year-old male suffering from persistent allergic rhinitis with comorbid chronic rhinosinusitis and asthma since the age of 18 years was studied. He complained of nasal obstruction, sneezing, cough, rhinorrhea and moderate dyspnea. He occasionally visited local ear-nose-throat clinics for his nasal symptoms, but gained only periodic symptom relief. The patient was treated with acupuncture, infrared radiation to the face and electro-acupuncture. Needles were inserted at bilateral LI20, GV23, LI4 and EX-1 sites with De-qi. Electro-acupuncture was performed simultaneously at both LI20 sites and additional traditional Korean acupuncture treatments were performed. Each session lasted for 10 min and the sessions were carried out twice a week for 5 weeks. The patient’s Mini-Rhinoconjunctivitis Quality-of-Life Questionnaire score decreased from 38, at the beginning of treatment, to 23, 3 weeks after the last treatment. The Total Nasal Symptom Score was reduced from six (baseline) to five, 3 weeks after the last treatment. There was significant clinical improvement in the forced expiratory volume in 1 s—from 3.01 to 3.50 l—with discontinuation of the inhaled corticosteroid, and no asthma-related complaints were reported. Further clinical studies investigating the effectiveness of acupuncture for the patients suffering from allergic rhinitis and/or rhinosinusitis with comorbid asthma are needed.
Study Protocol: effects of acupuncture on hot flushes in perimenopausal and postmenopausal women – a multicenter randomized clinical trial
Kun-Hyung Kim, Kyung-Won Kang, Hee-Jung Jung, Ji-Eun Park, So-Young Jung, Jun-Yong Choi, Sun-Mi Choi
Trials , 2008, DOI: 10.1186/1745-6215-9-70
Abstract: We aim to evaluate the effectiveness of Traditional Korean Acupuncture (TKA) in conjunction with usual care, compared to usual care alone, on hot flushes in perimenopausal and postmenopausal women in Korea.This study consists of a multi-center randomized controlled trial with 2 parallel arms. Participants included in the study will meet the following criteria: 1) a documented daily average hot flush score ≥ 10 for one week prior to the screening visit 2) not taking HRT and other pharmaceutical therapies which might affect hot flushes or other vasomotor symptoms.While maintaining usual care, the treatment group will receive acupuncture 3 times a week, for a total of 12 sessions over 4 weeks. The control group will receive usual care alone during the same period. Post-treatment follow-up will be performed one month after completing 12 sessions of acupuncture.This trial will provide evidence for the effectiveness of acupuncture as a treatment for hot flushes. The primary endpoint in both groups is a change in hot flush score from baseline to week 4 and/or week 8. As the secondary endpoint, we will employ the Menopause Rating Scale (MRS), a health-related quality of life questionnaire. Further analysis will examine the frequency, severity and difference in symptoms for daytime vs. nighttime hot flushes, sub-domain analysis of MRS, and participants' expectations of acupuncture treatment.Current Controlled Trials ISRCTN49335612Hot flushes are the most frequent climacteric symptom and a major cause of suffering in menopausal women [1,2]. Diminished overall quality of life, social distress and emotional embarrassment are also frequent complaints due to menopause-associated hot flushes [3].The prevalence of hot flushes varies according to ethnicity, region and cultural characteristics [4,5]. Most women experience hot flushes for 6 months to 2 years [4]. For many women, most menopause-related vasomotor symptoms including hot flushes tend to resolve spontaneously within a few
First Evaluation of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Vivax Malaria Endemic Regions in the Republic of Korea
Youn-Kyoung Goo, So-Young Ji, Hyun-Il Shin, Jun-Hye Moon, Shin-Hyung Cho, Won-Ja Lee, Jung-Yeon Kim
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0097390
Abstract: Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect and affects more than 400 million people worldwide. This deficiency is believed to protect against malaria because its global distribution is similar. However, this genetic disorder may be associated with potential hemolytic anemia after treatment with anti-malarials, primaquine or other 8-aminoquinolines. Although primaquine is used for malaria prevention, no study has previously investigated the prevalence of G6PD variants and G6PD deficiency in the Republic of Korea (ROK). Methods Two commercialized test kits (Trinity G-6-PDH and CareStart G6PD test) were used for G6PD deficiency screening. The seven common G6PD variants were investigated by DiaPlexC kit in blood samples obtained living in vivax malaria endemic regions in the ROK. Results Of 1,044 blood samples tested using the CareStart G6PD test, none were positive for G6PD deficiency. However, a slightly elevated level of G6PD activity was observed in 14 of 1,031 samples tested with the Trinity G-6-PDH test. Forty-nine of the 298 samples with non-specific amplification by DiaPlexC kit were confirmed by sequencing to be negative for the G6PD variants. Conclusions No G6PD deficiency was observed using phenotypic- or genetic-based tests in individuals residing in vivax malaria endemic regions in the ROK. Because massive chemoprophylaxis using primaquine has been performed in the ROK military to kill hypnozoites responsible for relapse and latent stage vivax malaria, further regular monitoring is essential for the safe administration of primaquine.
Anti-Obesity Effect of Lactobacillus gasseri BNR17 in High-Sucrose Diet-Induced Obese Mice
Ji-Hee Kang, Sung-Il Yun, Mi-Hee Park, Jun-Hong Park, So-Young Jeong, Han-Oh Park
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0054617
Abstract: Previously, we reported that Lactobacillus gasseri BNR17 (BNR17), a probiotic strain isolated from human breast milk, inhibited increases in body weight and adipocyte tissue weight in high-sucrose diet-fed Sprague-Dawley (SD) rats and reduced glucose levels in type 2 diabetes mice. In the current study, we conducted further experiments to extend these observations and elucidate the mechanism involved. C57BL/6J mice received a normal diet, high-sucrose diet or high-sucrose diet containing L. gasseri BNR17 (109 or 1010 CFU) for 10 weeks. The administration of L. gasseri BNR17 significantly reduced the body weight and white adipose tissue weight regardless of the dose administered. In BNR17-fed groups, mRNA levels of fatty acid oxidation-related genes (ACO, CPT1, PPARα, PPARδ) were significantly higher and those of fatty acid synthesis-related genes (SREBP-1c, ACC) were lower compared to the high-sucrose-diet group. The expression of GLUT4, main glucose transporter-4, was elevated in BNR17-fed groups. L. gasseri BNR17 also reduced the levels of leptin and insulin in serum. These results suggest that the anti-obesity actions of L. gasseri BNR17 can be attributed to elevated expression of fatty acid oxidation-related genes and reduced levels of leptin. Additionally, data suggested the anti-diabetes activity of L. gasseri BNR17 may be to due elevated GLUT4 and reduced insulin levels.
Entanglement Entropy of Nontrivial States
Eric Benedict,So-Young Pi
Physics , 1995, DOI: 10.1006/aphy.1996.0007
Abstract: We study the entanglement entropy arising from coherent states and one--particle states. We show that it is possible to define a finite entanglement entropy by subtracting the vacuum entropy from that of the considered states, when the unobserved region is the same.
Finite and Infinite Symmetries in (2+1)-Dimensional Field Theory
Roman Jackiw,So-Young Pi
Physics , 1992, DOI: 10.1016/0920-5632(93)90375-G
Abstract: These days, Franco Iachello is {\it the\/} eminent practitioner applying classical and finite groups to physics. In this he is following a tradition at Yale, established by the late Feza Gursey, and succeeding Gursey in the Gibbs chair; Gursey in turn, had Pauli as a mentor. Iachello's striking achievement has been to find an actual realization of arcane supersymmetry within mundane adjacent even-odd nuclei. Thus far this is the only {\it physical\/} use of supersymmetry, and its fans surely must be surprised at the venue. Here we describe the role of $SO(2,1)$ conformal symmetry in non-relativistic Chern--Simons theory: how it acts, how it controls the nature of solutions, how it expands to an infinite group on the manifold of static solutions thereby rendering the static problem completely integrable. Since Iachello has also used the $SO(2,1)$ group in various contexts, this essay is presented to him on the occasion of his fiftieth birthday.
Threshhold Singularities and the Magnetic Mass in Hot QCD
R. Jackiw,So-Young Pi
Physics , 1995, DOI: 10.1016/0370-2693(95)01509-4
Abstract: We discuss the recently devised one-loop gap equation for the magnetic mass of hot QCD. An alternative, and one would hope equivalent, gap equation is presented, which however shows no mass generation at the one-loop level.
Dimensionally Reduced Chern-Simons Terms and their Solitons
R. Jackiw,So-Young Pi
Physics , 1998,
Abstract: We consider models in which nonrelativistic matter fields interact with gauge fields whose dynamics are governed by the Chern-Simons term. The relevant equations of motion are derived and reduced dimensionally in time or in space. Interesting solitonic equations emerge and their solutions are described. Finally, we consider a Chern-Simons term in three-dimensional Euclidean space, reduced by spherical symmetry, and we discuss its effect on monopole and instanton solutions.
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