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Search Results: 1 - 10 of 1065 matches for " Shramana Mandal "
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Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report
Shramana Mandal,Bhawana A. Badhe
Case Reports in Pathology , 2012, DOI: 10.1155/2012/568062
Abstract: Malignant transformation of a mature cystic teratoma (MCT) is a very rare complication with an incidence of 0.17–2%;. The most common form of malignant transformation of the MCT is squamous cell carcinoma. Other tumors arising in MCT include basal cell carcinoma, sebaceous tumor, malignant melanoma, adenocarcinoma, sarcoma, and neuroectodermal tumor. However malignant transformation with metastatic deposits in the omentum is extremely rare. The present case highlights the rarity of the occurrence of an omental deposits in a case of mature cystic teratoma with malignant transformation.
Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report
Shramana Mandal,Bhawana A. Badhe
Case Reports in Pathology , 2012, DOI: 10.1155/2012/568062
Abstract: Malignant transformation of a mature cystic teratoma (MCT) is a very rare complication with an incidence of 0.17–2%;. The most common form of malignant transformation of the MCT is squamous cell carcinoma. Other tumors arising in MCT include basal cell carcinoma, sebaceous tumor, malignant melanoma, adenocarcinoma, sarcoma, and neuroectodermal tumor. However malignant transformation with metastatic deposits in the omentum is extremely rare. The present case highlights the rarity of the occurrence of an omental deposits in a case of mature cystic teratoma with malignant transformation. 1. Introduction Malignant transformation in a mature cystic teratoma (MCT) is extremely rare [1]. Its incidence is 0.17–2% of all cases. MCT with deposits in the omentum is even rarer. The exact incidence is not known. The prognosis of malignant transformation of the MCT is very poor [2]. Extensive literature search has revealed only 3 such cases. We report the fourth case of MCT with omental deposits of squamous cell carcinoma in a 56-year-old female. 2. Case Report A 56-year-old female presented with history of abdominal distension and pain for 5 months. On per vaginal examination, a mass was felt arising from the pelvis, which was cystic, nontender, and mobile. The border of the mass was not well defined. Grossly a multiloculated ovarian mass was received measuring ?cm in size with an area of capsular breech. Cut surface was multiloculated, cystic, filled with grumous material, hair, and tooth. A single solid island measuring ?cm was also identified, the cut surface of which was grey white and firm. Microscopical sections showed typical features of a mature cystic teratoma. The cyst wall was composed of ectodermal elements (Figure 1). Section from the solid areas showed well-differentiated squamous cell carcinoma arising from the surface epithelium (Figure 2). Omentum showed deposits of well-differentiated squamous cell carcinoma. A final diagnosis of malignant transformation of well-differentiated squamous cell carcinoma in a mature cystic teratoma with omental deposits was made. Figure 1: Shows typical features of a mature cystic teratoma. Cyst wall being composed of ectodermal elements. Figure 2: Section from the solid areas showed well-differentiated squamous cell carcinoma arising from the surface epithelium. 3. Discussion The mature cystic teratoma (MCT) is the most common germ cell tumor of ovary, comprising of more than 10–20% of all ovarian neoplasms [1]. It is composed of a well-differentiated derivation of all the three germ cell layers, that is, endoderm,
Calcifying epithelial odontogenic tumor: Report of two cases
Mandal Shramana,Varma Kachnar,Khurana Nita,Mandal A
Indian Journal of Pathology and Microbiology , 2008,
Abstract: Calcifying epithelial odontogenic tumor (CEOT) is a rare, benign odontogenic tumor. It constitutes 0.4-3% of all odontogenic tumors. There is only a single case, which has been reported in the Indian literature that too in cytology. Microscopically, these are composed of large sheets of epithelial cells, amorphous amyloid-like material and calcification. Although these lesions are benign, they can be locally aggressive, but malignant transformation and metastasis is rare. Considering its locally aggressive nature, appropriate management and long-term follow-up is recommended. We describe two cases of CEOT involving the hard palate and leading to facial alterations.
Fibroma with minor sex cord elements – an incidental finding in a normal sized ovary A case report with literature review
Shramana Mandal, Dipti Mahajan, Somak Roy, Meeta Singh, Nita Khurana
Diagnostic Pathology , 2007, DOI: 10.1186/1746-1596-2-46
Abstract: A case of fibroma with minor sex cord elements discovered incidentally in a normal sized ovary in a patient who presented with dysfunctional uterine bleeding is being presented. This is the first case report describing this entity in a normal sized ovary as an incidental finding.Ovarian fibroma with minor sex cord elements is a rare entity which was first described by Young and Scully in 1983. Only 8 cases of ovarian fibroma with minor sex cord elements have been reported till date [1-4]. We report a case of fibroma with minor sex cord elements of a normal sized ovary discovered incidentally in a patient who presented with dysfunctional uterine bleeding. This is a rare, distinct clinico-pathologic entity among unclassified sex cord stromal tumors and is the first case report describing, the incidental occurrence of this entity in a normal sized ovary.A 45 year old female, gravida 3, para 3, presented to the gynecology outpatient with complaints of something coming out of the vagina and menorrhagia since the past 6 months. Per speculum examination revealed first degree cervical descent with second degree cystocele and rectocele. On vaginal examination uterus was 6 weeks in size, retroverted and mobile with clear bilateral fornices were free. Abdominal ultrasonography was normal. A clinical diagnosis of dysfunctional uterine bleeding with second degree cervical descent along with second degree cystocele and rectocele was made. Since the patient had completed her family, a total abdominal hysterectomy along with bilateral salpingo-oophorectomy was performed.We received a specimen of uterus with cervix along with bilateral adnexa measuring 8 × 3.5 × 2.5 cm. The cervix was everted pearly white in colour with 4 cm long endocervical canal. The endometrium and myometrium thickness were 0.1 cm and 2 cm. The myometrium on serial slicing showed a focus of hemorrhage. The right ovary measured 2.5 × 2.5 × 1.5 cm and was externally covered by capsule. Cut surface of the ovary sho
Malignant peripheral nerve sheath tumor of the breast: case report
Kajal Dhingra, Shramana Mandal, Somak Roy, Nita Khurana
World Journal of Surgical Oncology , 2007, DOI: 10.1186/1477-7819-5-142
Abstract: A 38-year-old female presented with complaints of painless, hard breast lump for three months which was clinically suspected to be a ductal carcinoma with inconclusive fine needle aspiration cytology. Histopathology revealed a malignant spindle cell tumor which was confirmed to be malignant peripheral nerve sheath tumor on the basis of immunopositivity for vimentin, neurone specific enolase and S-100.To the best of our knowledge only six such case reports have been published in literature. The differential diagnosis of malignant peripheral nerve sheath tumor should be considered by the clinician as well as the pathologists in the work-up of a breast neoplasm as treatment and prognosis of this rare malignancy is different.Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma of the ectomesenchymal origin. It is the malignant counterpart of benign soft tissue tumors like neurofibromas and schwannomas and may follow them. Common sites include deeper soft tissues, usually in the proximity of a nerve trunk. MPNST in the breast is often unsuspected and the diagnosis may be missed unless clinical suspicion is high and immunohistochemistry carried outA 38-year old female patient presented to the surgical out patient department with complaints of a rapidly growing right breast lump for three months. There was no history of prior breast mass, pain, trauma, bleeding, discharge, or family history of breast cancer. On examination there was a single 3.5 × 3 × 3 cm, ill defined non tender, firm, fixed mass in the right upper outer quadrant. There was no retraction or ulceration of the overlying skin. Fine needle aspiration cytology (FNAC) suggested a malignant spindle cell tumor probably a malignant phylloides. An excisional biopsy was advised to confirm the diagnosis and to guide the further management.Grossly the specimen was a skin covered lumpectomy specimen measuring 5 × 4.4 × 4 cms. The cut sections revealed a firm infiltrative unencapsulated gray whi
Aggressive angiomyxoma of the vulva presenting as a pedunculated swelling
Mandal Shramana,Dhingra Kajal,Roy Somak,Khurana Nita
Indian Journal of Pathology and Microbiology , 2008,
Abstract: Aggressive angiomyxoma is a rare, locally aggressive soft tissue tumor that has high propensity for local recurrence. It involves mainly the pelvis, vulva, perineum, vagina and urinary bladder in adult women in the reproductive age. Considering its locally aggressive nature, appropriate management and long-term follow-up is necessary. We describe a case of a 22-year-old young pregnant patient presenting with a large pedunculated swelling on the left labia majora.
An Intervention Study in Malnutrition Among Infants in a Tribal Community of West Bengal
Mandal ON
Indian Journal of Community Medicine , 2005,
Abstract:
Revisiting Laws of Black Hole Mechanics and Violation of Null Energy Condition  [PDF]
Susobhan Mandal
Journal of High Energy Physics, Gravitation and Cosmology (JHEPGC) , 2019, DOI: 10.4236/jhepgc.2019.51004
Abstract: Most of the important and powerful theorems in General Relativity such as singularity theorems and the theorems applied for null horizons depend strongly on the energy conditions. However, the energy conditions on which these theorems are based on, are beginning to look at less secure if one takes into accounts quantum effects which can violate these energy conditions. Even there are classical systems that can violate these energy conditions which would be problematic in validation of those theorems. In this article, we revisit to a class of such important theorems, the laws of black hole mechanics which are meant to be developed on null like killing horizons using null energy condition. Then we show some classical and quantum mechanical systems which violate null energy condition based on which the above theorem stands.
Broken Charges Associated with Classical Spacetime Symmetries under Canonical Transformation in Real Scalar Field Theory  [PDF]
Susobhan Mandal
Journal of High Energy Physics, Gravitation and Cosmology (JHEPGC) , 2019, DOI: 10.4236/jhepgc.2019.51009
Abstract: We know from Noether’s theorem that there is a conserved charge for every continuous symmetry. In General Relativity, Killing vectors describe the spacetime symmetries and to each such Killing vector field, we can associate conserved charge through stress-energy tensor of matter which is mentioned in the article. In this article, I show that under simple set of canonical transformation of most general class of Bogoliubov transformation between creation, annihilation operators, those charges associated with spacetime symmetries are broken. To do that, I look at stress-energy tensor of real scalar field theory (as an example) in curved spacetime and show how it changes under simple canonical transformation which is enough to justify our claim. Since doing Bogoliubov transformation is equivalent to coordinate transformation which according to Einstein’s equivalence principle is equivalent to turn on effect of gravity, therefore, we can say that under the effect of gravity those charges are broken.
Heavy Metals in Soils around the Cement Factory inRockfort, Kingston, Jamaica  [PDF]
A. Mandal, M. Voutchkov
International Journal of Geosciences (IJG) , 2011, DOI: 10.4236/ijg.2011.21005
Abstract: This study deals with the distribution of heavy metals in soils around one of the most important industries in Kingston, Jamaica i.e. the Carib Cement factory at Rockfort. The dust emitted from the Caribbean Cement Company Limited (Carib Cement), located in Rockfort, Kingston, gets deposited in course of time over the soil, leaves and forms a grey cover on the surrounding soils. Geochemical analysis of the top soil, collected from the present study area has been undertaken to assess the impact of the dust emitted from the cement factory and its effect on the surrounding ecosystem. A total of seventeen top soil samples of 0-10 cm depth were collected from the close vicinity of the Rockfort and the Harbour view area and analysed by INAA, AAS, XRF for major, minor and trace elements. Results show that the top soils of the study area are enriched in Pb, Zn, Cr, Cd, V, Pb, and Hg which are released into the air from the cement kilns. Results show that the soils are enriched in Ca with a maximum value of 18% followed by Al, Fe and Na. Heavy metals in the soils of the study area shows relatively high concentrations of zinc with a maximum of 132 ppm followed by Cr (57) ppm and Pb (32) ppm. Maximum concentrations were found in soils sampled at a distance of 2-3 m from the cement factory as opposed to samples collected much further ie from the Harbour View area. High concentrations of the heavy metals in the soils near the cement factory as opposed to those further away can be due to the emissions from the factory. A significant contribution can also come from traffic emissions as the study area is located along one of the busiest street of Kingston, Jamaica.
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