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Search Results: 1 - 10 of 1204 matches for " Shinji Iizuka "
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Random fields on model sets with localized dependency and their diffraction
Yohji Akama,Shinji Iizuka
Mathematics , 2011, DOI: 10.1007/s10955-012-0588-5
Abstract: For a random field on a general discrete set, we introduce a condition that the range of the correlation from each site is within a predefined compact set D. For such a random field omega defined on the model set Lambda that satisfies a natural geometric condition, we develop a method to calculate the diffraction measure of the random field. The method partitions the random field into a finite number of random fields, each being independent and admitting the law of large numbers. The diffraction measure of omega consists almost surely of a pure-point component and an absolutely continuous component. The former is the diffraction measure of the expectation E[omega], while the inverse Fourier transform of the absolutely continuous component of omega turns out to be a weighted Dirac comb which satisfies a simple formula. Moreover, the pure-point component will be understood quantitatively in a simple exact formula if the weights are continuous over the internal space of Lambda Then we provide a sufficient condition that the diffraction measure of a random field on a model set is still pure-point.
RUNX3 Has an Oncogenic Role in Head and Neck Cancer
Takaaki Tsunematsu, Yasusei Kudo, Shinji Iizuka, Ikuko Ogawa, Tsuyoshi Fujita, Hidemi Kurihara, Yoshimitsu Abiko, Takashi Takata
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0005892
Abstract: Background Runt-related transcription factor 3 (RUNX3) is a tumor suppressor of cancer and appears to be an important component of the transforming growth factor-beta (TGF-?)-induced tumor suppression pathway. Surprisingly, we found that RUNX3 expression level in head and neck squamous cell carcinoma (HNSCC) tissues, which is one of the most common types of human cancer, was higher than that in normal tissues by a previously published microarray dataset in our preliminary study. Therefore, here we examined the oncogenic role of RUNX3 in HNSCC. Principal Findings Frequent RUNX3 expression and its correlation with malignant behavior were observed in HNSCC. Ectopic RUNX3 overexpression promoted cell growth and inhibited serum starvation-induced apoptosis and chemotherapeutic drug induced apoptosis in HNSCC cells. These findings were confirmed by RUNX3 knockdown. Moreover, RUNX3 overexpression enhanced tumorsphere formation. RUNX3 expression level was well correlated with the methylation status in HNSCC cells. Moreover, RUNX3 expression was low due to the methylation of its promoter in normal oral epithelial cells. Conclusions/Significance Our findings suggest that i) RUNX3 has an oncogenic role in HNSCC, ii) RUNX3 expression observed in HNSCC may be caused in part by demethylation during cancer development, and iii) RUNX3 expression can be a useful marker for predicting malignant behavior and the effect of chemotherapeutic drugs in HNSCC.
Diamond Particles Deposited among Nickel/Copper Particles in Energy Controlled CH4/H2 RF Discharge Plasmas  [PDF]
Junichi Emi, Satoru Iizuka
Journal of Surface Engineered Materials and Advanced Technology (JSEMAT) , 2012, DOI: 10.4236/jsemat.2012.23025
Abstract: Formation of diamond particles was investigated in an energy-controlled CH4/H2 radio-frequency (RF) discharge plasma. Here, in particular, it was examined how diamond particles grew on a nickel substrate under an influence of Cu vapor that was supplied from a heated Cu wire. Here, the plasma was generated by a hollow-magnetron-type (HMT) RF plasma source at the frequency of 13.56 MHz. Total pressure was kept at 100 mTorr. Diamond particles grew besides Ni and Cu particles. From Raman spectrum the substrate surface was covered with thin graphite film deposited as a background layer. It was shown that diamond could grow in a self-organized manner even when the other atomic gas species such as Ni and Cu were contained in the gas at the same time during the growth process.
Simple Relationship Analysis between L-Band Backscattering Intensity and the Stand Characteristics of Sugi (Cryptomeria japonica) and Hinoki (Chamaecyparis obtusa) Trees  [PDF]
Kotaro Iizuka, Ryutaro Tateishi
Advances in Remote Sensing (ARS) , 2014, DOI: 10.4236/ars.2014.34015
Abstract: In this study, we have performed an analysis between the L-band backscattering intensity derived from the slope corrected ALOS PALSAR remote sensing data and the in-situ stand biophysical parameter of Sugi (Cryptomeria japonica) and Hinoki (Chamaecyparis obtusa) trees at the forests of Chiba Prefecture, Japan. Diameter at breast height (DBH), tree height, and stem volume were statistically compared with the slope corrected sigma naught backscattering in an empirical approach. It was found that the relationship between the backscattering and the stand characteristics was strongly dependent on species showing different trends between the Sugi and Hinoki trees. The Hinoki trees showed an increasing backscattering with increasing parameters (higher DBH, higher Tree height and higher stem volume), as it was mentioned on various researches, while the Sugi tree showed and decreasing backscattering with increasing parameters. We have also found for the Sugi trees that the backscattering is affected strongly by the number of stems. We have assumed that this is because of the characteristics of the Sugi trees which have high moisture content in the heartwood of the stem, compared with other tree species in Japan. The results pave the way to the possibility for estimating biophysical parameters within the forests of Japan by considering such trends and at highly rugged areas by using slope corrected imagery of the SAR data.
On Historical Value at Risk under Distribution Uncertainty  [PDF]
Atsushi Iizuka, Yumiharu Nakano
Journal of Mathematical Finance (JMF) , 2015, DOI: 10.4236/jmf.2015.52010
Abstract: We investigate the asymptotics of the historical value-at-risk under capacities defined by sublinear expectations. By generalizing Glivenko-Cantelli lemma, we show that the historical value-at-risk eventually lies between the upper and lower value-at-risks quasi surely.
Production of CH4 in a Low-Pressure CO2/H2 Discharge with Magnetic Field  [PDF]
Keisuke Arita, Satoru Iizuka
Journal of Materials Science and Chemical Engineering (MSCE) , 2015, DOI: 10.4236/msce.2015.312011
Abstract: Production of CH4 has been established using a low-pressure square-pulse cross-field CO2/H2 discharge with magnetic field. The conversion rate from CO2 to CH4 was investigated by changing the discharge parameters such as applied power and discharge distance, together with magnetic field strength. Carbon dioxide was reduced by hydrogen. The discharge took place across the magnetic field inside a glass tube. Decomposition of CO2 and CH4 selectivity are found to be dependent on power density. Energy efficiency for methane production is increased in a narrow discharge. Preferable improvements of CO2 decomposition, CH4 selectivity, and energy efficiency were established.
Analysis of Langmuir Probe Characteristics for Measurement of Plasma Parameters in RF Discharge Plasmas  [PDF]
Kohgi Kato, Satoru Iizuka
Journal of Applied Mathematics and Physics (JAMP) , 2016, DOI: 10.4236/jamp.2016.49185
Abstract: A simple method for measuring RF plasma parameters by means of a DC-biased Langmuir probe is developed. The object of this paper is to ensure the reliability of this method by using the other methods with different principles. First, Langmuir probe current \"\"response on RF voltage \"\" superimposed to DC \"\" biased probe was examined in DC plasmas. Next, probe current response of DC biased probe in RF plasmas was studied and compared with the first experiment. The results were confirmed by using an emissive prove method, an ion acoustic wave method, and a square pulse response method. The method using a simple Langmuir probe is useful and convenient for measuring electron temperature \"\" , electron density \"\" , time-averaged space potential \"\" , and amplitude of space potential oscillation \"\" in RF plasmas with a frequency of the order of \"\" .
Supergravity, Supermembrane and M(atrix) model on PP-Waves
Norihiro Iizuka
Physics , 2002, DOI: 10.1103/PhysRevD.68.126002
Abstract: In the first part of this paper, we study the back-reaction of large-N light cone momentum on the maximally supersymmetric anti-pp-wave background. This gives the type IIA geometry of large-N D0-branes on curved space with fluxes. By taking an appropriate decoupling limit, we conjecture a new duality between string theory on that background and dual field theory on D0-branes which we derive by calculating linear coupling terms. Agreement of decoupling quantities, SO(3) \times SO(6) isometry and Higgs branch on both theories are shown. Also we find whenever dual field theory is weakly coupled, the curvature of the geometry is large. In the second part of this paper, we derive the supermembrane action on a general pp-wave background only through the properties of null Killing vector and through this, derive the Matrix model.
Preventive Effects of Salacia reticulata on Obesity and Metabolic Disorders in TSOD Mice
Tomoko Akase,Tsutomu Shimada,Yukiko Harasawa,Tomohide Akase,Yukinobu Ikeya,Eiichi Nagai,Seiichi Iizuka,Gojiro Nakagami,Shinji Iizaka,Hiromi Sanada,Masaki Aburada
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/nep052
Abstract: The extracts of Salacia reticulata (Salacia extract), a plant that has been used for the treatment of early diabetes, rheumatism and gonorrhea in Ayurveda, have been shown to have an anti-obesity effect and suppress hyperglycemia. In this study, the effects of Salacia extract on various symptoms of metabolic disorder were investigated and compared using these TSOD mice and non-obese TSNO mice. Body weight, food intake, plasma biochemistry, visceral and subcutaneous fat (X-ray and CT), glucose tolerance, blood pressure and pain tolerance were measured, and histopathological examination of the liver was carried out. A significant dose-dependent decline in the gain in body weight, accumulation of visceral and subcutaneous fat and an improvement of abnormal glucose tolerance, hypertension and peripheral neuropathy were noticed in TSOD mice. In addition, hepatocellular swelling, fatty degeneration of hepatocytes, inflammatory cell infiltration and single-cell necrosis were observed on histopathological examination of the liver in TSOD mice. Salacia extract markedly improved these symptoms upon treatment. Based on the above results, it is concluded that Salacia extract has remarkable potential to prevent obesity and associated metabolic disorders including the development of metabolic syndrome. 1. Introduction Ayurvedic medicine is an ancient system of healthcare that is native to the Indian subcontinent. It is presently in daily use by millions of people in India, Nepal and Sri Lanka [1]. Salacia reticulata is a climbing plant in the Hippocrateaceae family that has been used traditionally in Indian Ayurvedic medicine and is said to be effective for the prevention and treatment of diabetes, rheumatism, gonorrhea and skin diseases [2]. The major phytochemical components of Salacia include Triterpenes [3] such as antileukemic Isoiguesterin [4], Aldose reductase and -glucosidase inhibitors, such as kotalanin 16-acetate [5], Kotalanol [2] and potent antioxidant, quinine methides [6], polyphenol constituents with -glucosidase and aldose reductase inhibitory activities, Mangiferin [7, 8] and potent -glucosidase inhibitor, Salacinol [9, 10]. There are evidences to suggest that the member of Salacia family are efficacious for treatment of metabolic disorders, obesity [11], hyperinsulinemia [12], cardiac lipid metabolism [13] and cardiac hypertrophy [14], and it is expected that the salacia family will be efficacious in the treatment of metabolic disorders. In contrast, Ratnasooriya et al. reported that a large dose of S. reticulata root extract could be hazardous to
Solvability of the Economic Input-Output Equation by Time Irreversibility  [PDF]
Shinji Miura
Advances in Linear Algebra & Matrix Theory (ALAMT) , 2014, DOI: 10.4236/alamt.2014.43013
This paper reinterprets the economic input-output equation as a description of a realized situation without considering decision making. This paper uses the equation that the self-sufficiency rate is added to the Leontief type, and discusses its solvability. The equation has a unique solution if and only if each part of the relevant society satisfies the space-time openness condition. This condition means that commodities which a part of the relevant society possesses are not all inputted to its inside. Moreover, if the process of input and output is time irreversible, each part of the relevant society satisfies the space-time openness condition. Therefore, the solvability of the equation is guaranteed by time irreversibility. This proposition seems to be relevant to the grandfather paradox which is a type of time paradox.
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