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Search Results: 1 - 10 of 399 matches for " Shervin Eslami;Mirshahi "
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Effect of calcium content on the microstructure, hardness and in-vitro corrosion behavior of biodegradable Mg-Ca binary alloy
Harandi, Shervin Eslami;Mirshahi, Mohammad;Koleini, Shahriar;Idris, Mohd Hasbullah;Jafari, Hassan;Kadir, Mohammed Rafiq Abdul;
Materials Research , 2013, DOI: 10.1590/S1516-14392012005000151
Abstract: effect of calcium addition on microstructure, hardness value and corrosion behavior of five different mg-xca binary alloys (x = 0.7, 1, 2, 3, 4 wt. (%)) was investigated. notable refinement in microstructure of the alloy occurred with increasing calcium content. in addition, more uniform distribution of mg2ca phase was observed in a-mg matrix resulted in an increase in hardness value. the in-vitro corrosion examination using kokubo simulated body fluid showed that the addition of calcium shifted the fluid ph value to a higher level similar to those found in pure commercial mg. the high ph value amplified the formation and growth of bone-like apatite. higher percentage of ca resulted in needle-shaped growth of the apatite. electrochemical measurements in the same solution revealed that increasing ca content led to higher corrosion rates due to the formation of more cathodic mg2ca precipitate in the microstructure. the results therefore suggested that mg-0.7ca with the minimum amount of mg2ca is a good candidate for bio-implant applications.
Production and purification of recombinant streptokinase using pMAL expression vector
Jafari R,Mirshahi M
Tehran University Medical Journal , 2007,
Abstract: Background: Streptokinase (SK) is an effective and specific thrombolytic treatment of acute myocardial infarction. Despite its significant limitations, streptokinase remains the drug of choice particularly in countries with poorer economies because of its relatively low cost. In this study, the production and purification of streptokinase using a pMAL expression vector were evaluated. Methods: The pMAL vector, including the skc gene, obtained from Streptococcus equisimilis H46A, was transformed into E. coli BL21 to produce the soluble active fusion protein SK-MBP. The conditions of SK production were optimized by manipulating temperature, induction time and IPTG concentrations. This protein was purified by DEAE-sepharose column chromatography and the final purity was determined and activity of purified SK-MBP was measured using a synthetic substrate (S2251). Results: After optimizing the production conditions, SK-MBP was the major portion of total protein. Purified SK-MBP formed a single band using SDS-PAGE and had high biological activity. Conclusion: In this study we used pMAL expression vector to produce SK-MBP in E. coli BL21. Using this method we prevented the accumulation of inclusion bodies in spite of the high level of production of SK-MBP. Choosing a suitable host organism for the production of recombinant proteins is one of the most important factors that influence the level of desired protein production. Further studies are recommended to test other host organisms for this purpose.
Bilateral optic nerve head hemangioma in Von Hippel Lindau disease: Report of a case with severe visual loss
Abdollahi A,Mirshahi A
Acta Medica Iranica , 2001,
Abstract: A 22 year-old woman presented with gradual visual loss in her right eye since 1990. Medical and family histories were unremarkable. Her visual acuity was 20/80 and 20/20 in right and left eyes respectively. Slit lamp examination was quite normal with no relative afferent papillary defect.Fundi of both eyes revealed subretinal lesion with optic nerve head involvement and subretinal fluid in papillomacular bundle with macular pucker in right eye. Whole body MRI revealed a large hemangioma in the spinal canal. In 1998 the patient ahsd significant visual loss at both eyes. This is the first report of Von hippel disease with bilateral optic nerve hemangioma in Iran.
Accuracy of Contrast-Enhanced Computed Tomography (CT) Scan in Differentiation of Malignant Parotid Neoplasms: New Approaches for Better Diagnosis
Shervin Sharifkashany
Iranian Journal of Radiology , 2009,
Abstract: Introduction: One of the most important preoperative concerns in patients with parotid neoplasms is the probability of malignancy. In this study, we evaluated the accuracy of different findings of contrast-enhanced CT scan in differentiation of malignant parotid neoplasms. Also we have presented the results of new approaches in this regard. Materials and Methods: All patients with noninflammatory parotid masses were considered in this study in a one year period. All patients with one or more of these conditions were excluded from the study: age under 15 years old, patients who underwent previous biopsy or fine needle aspiration and the time interval between imaging and surgery was more than 10 days. Finally 33 patients were entered to the study. Of all cases, 18 (54.6%) were male and the mean age was 43.3±17.6 years (15-78). All patients underwent a facial and neck contrast enhanced CT scanning in the supine position and axial sections (5 mm thickness and 5 mm interval) were performed from the temporomandibular joint (TMJ) upper border to the thoracic inlet. Ten seconds after intravenous bolus injection of 100cc Omnipaque 240 mg I/cc, imaging began. For all parotid masses, 8 imaging findings were evaluated which consisted of the tumor size [maximum value of parotid tumor short-axis diameter], Hunsfield unit (HU) [considered in section performed 120 seconds after contrast medium injection; region of interest (ROI) was considered as a 5 mm diameter circle in the central part of the region with the highest visual density of the mass],visual density, heterogenecity, tumor border, tumor location, tumor extension to the other neck spaces and cervical adenopathy. Surgery was performed for all patients and the histopathologic evaluation was done as gold standard. For dichotomous variables, the diagnostic indices [including sensitivity(Se.), specificity (Sp), positive predictive value (PPV), negative predictive value(NPV), positive likelihood ratio (LR+) and negative likelihood ratio (LR-)] were calculated. For continuous variables (including tumor size and HU) the receiving operating characteristic (ROC) curve was assessed and the selected cut points were yielded. Results: Totally 13 patients showed malignant tumor in pathology (39.4%). Deep lobe involvement, extension to the other neck spaces and adenopathy were higher in malignant tumors [all P-Values<0.018]. Among dichotomous variables, the best Se. was for enhancement pattern (Se=0.85 while Sp=0.4) and the best Sp. was for extension and adenopathy [Sp=0.95 for both, Se=0.38 for extension and 0.46 for aden
Antimicrobial Assay of Chlorhexidine-Wetted Textile Napkins for Surgical Site Disinfection in Ocular Surgery  [PDF]
Amir Reza Daneshmand Eslami
International Journal of Clinical Medicine (IJCM) , 2013, DOI: 10.4236/ijcm.2013.412099

Background: As a new intraoperative disinfection method, chlorhexidine-wetted textile napkins have been employed in order to cover the upper and lower eyelid edges, eyelid skin, eyelashes, lid margins and palpebral conjunctiva during phacoemulsification cataract extraction. This study was conducted to compare the antimicrobial activity of textile napkins before and after their use. Methods: This study evaluated 80 textile napkins wetted with 0.02% aqueous solution of chlorhexidine. All textile napkins were divided into groups. The study group consisted of 60 used textile napkins which were collected from 29 patients (30 eyes) at the end of phacoemulsification, and the control group included 20 unused sterile textile napkins. Antimicrobial assay was performed by means of measuring the growth inhibition zones of the standard or clinical isolate strains under the textile napkins on the surface of agar media. Results: The number of textile napkins and the diameter of the growth inhibition zones (mm) in the study group and in the control group relating to gram-positive, gram-negative, and fungi were: 24/31 vs. 8/31, 32/30 vs. 8/30, and 4/30 vs. 4/30. The diameter of the growth inhibition zones of gram-positive bacteria was more than other investigated microorganisms. In the growth inhibition zones, exogenous microorganism colonies were not found. Conclusion: Antimicrobial activity of textile napkins wetted with 0.02% aqueous solution of chlorhexidine against gram-positive bacteria is more than gram-negative bacteria and fungi, and is preserved to the end of the

Explanation of Capacitive Performance of the Plasma in Damavand Tokamak  [PDF]
Shervin Goudarzi, Fatemeh Dadgarnejad, Hojat Babaee
Open Journal of Applied Sciences (OJAppS) , 2015, DOI: 10.4236/ojapps.2015.52004
Abstract: In this work capacity of tokamak plasma is calculated using modeling of tokamak configuration as toroidal and coaxial capacitor. This value is very important and plays an important role in time- varying regimes in tokamak. For exact simulation of plasma behavior, this amount will be added to circuit equations and transport codes. Since capacitive properties of tokamak cause production of a radial electric field, it deserves our special attention.
Viewing the Future of Nuclear Power Plants Following the 2011 Disaster in Fukushima Nuclear Power Plant  [PDF]
Shervin Goudarzi, Fatemeh Dadgarnejad, Hojat Babaee
Open Journal of Applied Sciences (OJAppS) , 2015, DOI: 10.4236/ojapps.2015.55022
Abstract: Concerning the increasing global energy demand, the current paper considers nuclear energy as a solution. Within this context, the 2011 disaster in Fukushima Nuclear Power Plant and, particularly, the technical disorders in boiling water reactors are explained. The deficiency of safety technique in boiling water reactors is explained. The deficiencies in safety procedure of this type of reactors manifested during 2011 earthquake and subsequent tsunami are explained. To complete the discussion, the newer technologies of reactors enabling them to act more safely during natural disasters are introduced. These investigations indicate that despite improvement in the fission reactor technologies, the danger embedded in them still remains. Therefore, the nuclear fusion using Deuterium-Tritium reaction is the best way forward for energy production in the future, and the best candidate of this type of reactors is Tokamak.
A Compact Test System for Simulating Multipath Interference  [PDF]
Mohammed Eslami, Howard I. Bassen
Open Journal of Antennas and Propagation (OJAPr) , 2014, DOI: 10.4236/ojapr.2014.22002

Fading and inter-symbol interference (ISI) arising from multipath effects are a common source of both latency and packet errors in wireless communications. Test methods often require large environments to produce long delays that are enough to affect the communications between a transmitter and receiver. This paper presents a simple, compact test method to produce and isolate effects from multipath interference simulating these effects produced by discrete distances. Signals with controlled delays can be created and combined using multiple antennas in two isolated small (2 foot/60 cm) cubes constructed with microwave absorber. We demonstrated this with a pulsed RF signal and a signal from an 802.11 n access point with an internal antenna. This method can be further extended to provide a compact test-bed for almost any wireless interference or coexistence test.

Comparison of Culture and PCR Methods for the Detection of John s Disease in Milk Samples
Majid Eslami
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2011.614.618
Abstract: Mycobacterium paratuberculosis (MAP) is the cause of John s disease or paratuberculosis. This is economically one of the important infection diseases in cattle and ruminant industries. This disease is manifested as granulomatosis entrocolitis, lymphadenitis and inflammation local lymphatic vessels. The typical sign of this disease is the progressive loss of patient weight. Considering the importance of detection of this disease in this study, two methods, culture and PCR were used for the identification of this microorganism. In this study 100 milk samples from apparently healthy cows and 100 milk samples from cows that have been suspicious of John's disease were taken from cattle Sarab region. Direct microscope observation after ziehl-neelsen staining was done. Then, bacterial culture on specific medium was carried out and finally, identification of Mycobacterium avium paratuberculosis was examined using PCR and specific primers. Using direct observation, culture and PCR analyses showed that from 100 healthy cow milk samples, 8, 9 and 12 samples were positive MAP for each method, respectively. The results of direct observation, culture and PCR analyses on affected cows were 15, 40 and 44, respectively. The results of this study showed that culture and PCR analyses methods are important in the identification of the causes of this disease. Therefore, considering the frequency of the disease in the studied region, either of those methods can be used in the microorganism identification.
Hearing Recovey in Patients Suffering Sudden Deafness
Parviz Eslami
Audiology , 1992,
Abstract: The study included 80 patients treated for sudden deafness over the last 5-7 years. Case history, laboratory findings, pure-tone audiogram and electronystagmography (ENG) findings were noted. If any abnormalities had been recorded in ENG studies, the studies were redone. ORL status was redefined and audiograms were obtained in all patients. When becoming ill, the 80 patients had not differed from the normal population in common cardiovascular risk factors. None of them had had signs of viral infection (paired serum samples had been taken at 2-week intervals; routine examinations had been done for common viral antigens). As many as 31 of the 80 patients with acute hearing loss had had abnormalities such as spontaneous nystagmus (PN), hypoexcitability (HE) and directional preponderance (DP) in the bithermal caloric tests (+44 degrees C, + 30 degrees C) of their ENG studies. Twenty of the 31 patients still had abnormal ENG studies after 5-7 years. Only 1 subject had positional nystagmus, and none had subjective vertigo. Patients with an abnormal ENG study showed a poor recovery of the speech reception threshold, whereas those with a normal ENG study showed slightly significant (p less than 0.05) recovery.
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