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Search Results: 1 - 10 of 280 matches for " Seynabou Fall "
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Renal Disease among HIV Positive Patients in Senegal  [PDF]
Khodia Fall, Mouhamadou Moustapha Cissé, Ahmed Tall Lemrabott, Maria Faye, Mouhamed Cherif Dial, Atoumane Faye, Seynabou Fall, Moustapha Faye, Alex Keita, Mansour Mbengue, Seynabou Diagne, Niakhaleen Keita, Bacary Ba, Abdou Niang, Boucar Diouf, El Hadji Fary Ka
Open Journal of Nephrology (OJNeph) , 2017, DOI: 10.4236/ojneph.2017.74012
Abstract: Introduction: Renal disease (RD) in human immunodeficiency virus (HIV) infection is a decisive turning point in the development and prognosis of this disease. In Africa, the prevalence varies between 2.5% and 48.6%. In Senegal, little data are available in the literature. The objective of our study was to describe the epidemiological, clinical, paraclinical, therapeutic and progressional aspects in patients living with HIV (PLWHIV). Patients and methods: This was a retrospective, descriptive and analytical study carried out over a 10-year period in the Department of Internal Medicine and Nephrology at the Aristide Le Dantec Hospital in Dakar, Senegal. We included all 15-year old and above PLHIV with available CD4 count and viral load. Results: Out of 248 PLHIV, 32 had kidney disease (KD), which means a hospital prevalence of 12.9%. The mean age was 51.22 ± 10 years (extremes of 36 and 77 years) with a sex ratio (male/female) of 1.28. Renal signs were dominated by glomerular nephropathy syndrome. It was present at 80%. Tubulo-interstitial nephropathy syndrome and chronic uremic syndrome accounted for 6.25% and 3.1% of cases, respectively. Renal function Impairment was present in 21 patients with 18 cases of acute kidney injury (85.7%) and 3 cases of chronic renal failure (14.3%), including 2 in stage 5 of chronic kidney disease. Renal biopsy (RB) was indicated and performed in 20 (62.5%) patients with glomerular signs in 12 patients (60%). Glomerular lesions were dominated by focal and segmental glomerulosclerosis (FSGS) in 6 cases, membraneous nephropathy (MN) in 4 cases and minimal change disease (MCD) in 2 cases. Tubulo-interstitial and vascular lesions were present in 45% and 12.5% of cases, respectively. In highly active antiretroviral therapy (HAART), 12 (37.5%) patients had total remission, 9 (28.12%) had partial remission. One (3.12%) death from severe metabolic acidosis on chronic renal failure was deplored. Conclusion: This study illustrates the high prevalence of RD in PLHIV in our exercise context.
Biermer Disease: Initial Presentation and Follow-Up of 66 Patients in Internal Medicine Department in Senegal  [PDF]
Seynabou Fall, Nafissatou Diagne, Oulimata-Dior Diop, Boundia Djiba, Fatou-Samba-Diago Ndiaye, Abdoulaye Pouye
International Journal of Clinical Medicine (IJCM) , 2016, DOI: 10.4236/ijcm.2016.79064
Abstract: Pernicious anemia in black people, is little known. Through this study we assess its diagnostic and evolutive aspects, and compare vitamin therapy B12 intramuscular and oral. Sixty six Biermer disease patients followed (January 2000-June 2014) at Internal Medicine Department of Aristide Le Dantec University Teaching Hospital (Senegal) are included. They were 26 men and 46 women (gender ratio: 0.65), who had a mean age of 47.84 years ± 15.25 years. Patients consulted for anemia (65 cases), acquired melanodermia (36 cases), gastrointestinal symptoms (30 cases), peripheral neuropathy (27 cases), venous thrombosis (2 cases), acute depression (1 case). Macrocytosis was observed in 52 cases. The mean hemoglobin in the vitamin B12 intramuscular group (52 patients) or oral group (14 patients) was the inclusion: 6.55 g/dl ± 3.12 g/dl vs 6.52 g/dl ± 2.18 g/dl (p = 0.04); and at day 8 treatment: 8.69 g/dl ± 2.49 g/dl vs 8.85 g/dl ± 1.9 g/dl (p = 0.43). Neurological and vascular presentations are unusual in contrast to macrocytic anemia. Oral administration of vitamin B12, simple and effective should be recommended in country with limited resources.
Pernicious Anemia Associated Autoimmune Diseases in a Sub Saharian African Internal Medicine Service  [PDF]
Abdoulaye Pouye, Seynabou Fall Dieng, Daher Abdoukarim Oumar, Fatou Samba Diago N’Diaye, Nafissatou Diagne Sakho, Atoumane Faye, Souhaibou N’Dongo
Open Journal of Internal Medicine (OJIM) , 2014, DOI: 10.4236/ojim.2014.43009
Abstract: Introduction: Pernicious anemia is an autoimmune disease. It is characterized by the presence of an autoimmune atrophic gastritis and various autoantibodies that lead to a vitamin B12 deficiency responsible for a macrocytic anemia. It is frequently associated with other specific or non-organ- specific autoimmune diseases. We report six patients with pernicious anemia associated with other autoimmune diseases. Patients and Results: There were six patients (4 females/2 males), mean age of 39.67 years. In all cases it was found macrocytic anemia. The average Hb was 6.08 g/dl and the average MGV: 110.67 fl. Bone marrow aspiration was performed in all patients. Megaloblastosis compatible with a lack of vitamin B12 or folic acid was constant. Determination of serum vitamin B12 was low in all cases while folic acid levels were within standards. Immuno- logically it was found in all patients, a positivity of anti-intrinsic factor antibody and/or anti- parietal cells antibody at rates up to 67 times over normal ranges. Pernicious anemia was associated with autoimmune thyroid dysfunction in 4 patients. It was two cases of Hashimoto thyroiditis at hypothyroidic phase (high TSHus, thyréoperoxydase anti-antibody positive (over 10 N) in both cases and Graves’ disease in the two other cases. Pernicious anemia was associated with a syndrome of primary antiphospholipid antibody in a case. Furthermore pernicious anemia was found in a patient autoimmune type 1 diabetes with strongly positive anti -GAD antibodies and rheumatoid arthritis by retaining it in the diagnosis of multiple autoimmune syndrome. Conclusion: These cases illustrate the existence of the association of pernicious anemia with other autoimmune diseases in our context. This should encourage practitioners to seek hided autoimmune diseases when they consider the diagnosis of pernicious anemia.
Rosai-Dorfman Disease: Two Cases Report and Literature Review  [PDF]
Atoumane Faye, Nafissatou Diagne Sakho, Fatou Samba D. Ndiaye, Seynabou Fall, Awa Cheikh Ndao Mbengue, Boundia Djiba, Baidy Sy Kane, Souhaibou Ndongo, Abdoulaye Pouye
Open Journal of Internal Medicine (OJIM) , 2015, DOI: 10.4236/ojim.2015.52004
Abstract: The lymph node is the revelation mode of several pathology. In tropical area, their etiology are dominated by tuberculosis and hemopathy. Some etiology such as histiocytosis are rarely mentioned. We report two cases of Rosai-Dorfman-Destombes disease. The first observation concerned a patient of 45 years without pathological antecedent, who had a inguinal and cervical tumoral lymph nodes. This evolved in a feverish poor general condition. Infection research was negative. Morphological explorations found deep lymph nodes. The excision biopsy examination concluded to Rosai-Dorfman-Destombes disease. The second observation concerned a patient of 40 years without pathological antecedent, who had a chronic non-inflammatory left supra-collarbone lymph node, associated with poor general condition and fever. X-ray showed mediastinal lymph nodes and ultra-sonography showed mesenteric lymph nodes, and latero-aortic lymph nodes. The examination of the excision biopsy was for Rosai Dorfman Destombes disease. The difficulty of diagnosis in our regions based on technical tray lack and our patients financial limits. Also this disease is rarely mentioned first. This is often the source of considerable diagnostic delay noted in our two patients and therefore the initiation of an untimely anti-tuberculosis treatment.
Kimura’s Disease: A Case Report and Literature Review  [PDF]
Atoumane Faye, Nafissatou Diagne Sakho, Awa Cheikh Ndao Mbengue, Fatou Samba D. Ndiaye, Seynabou Fall, Boundia Djiba, Baidy Sy Kane, Souhaibou Ndongo, Abdoulaye Pouye
Open Journal of Internal Medicine (OJIM) , 2015, DOI: 10.4236/ojim.2015.52003
Abstract: Kimura’s disease, common pathology in the East, responsible of chronic neck swelling is rarely reported in sub-Saharan Africa. We reported a case which was observed in the internal medicine department of Aristide Le Dantec hospital in Dakar. This was a young 15-year-old, with no particular disease history, who had recurrent non-inflammatory swelling next to the left zygomatic bone associated with itching. Biology revealed an inflammatory syndrom, eosinophilia and increased serum IgE. The histological examination of the mass biopsy concluded to Kimura disease. The corticosteroid has reduced the size of the mass within a few weeks of treatment. Kimura’s disease is unknown in our regions. His painless character and chronic evolution delay the time of diagnosis. This case proves the reality of this disease, which must find a place in the diagnosis approach of cervical swelling.
Severity of the Rheumatoid Arthritis in Sub-Saharan Africa: Study of 403 Senegalese Observations  [PDF]
Moustapha Niasse, Ba?dy Sy Kane, Abdoul Aziz Ndiaye, Awa Cheikh Ndao, Boundia Djiba, Seynabou Fall, Ngoné Diaba Diack, Fatimata Bintou Sall, Michel Assane Ndour, Nafy Diagne, Atoumane Faye, Biram Codou Fall, Souha?bou Ndongo, Abdoulaye Pouye
Open Journal of Internal Medicine (OJIM) , 2017, DOI: 10.4236/ojim.2017.74016
Abstract: Introduction: We assess the severity of the rheumatoid arthritis in a Senegalese African black population. Patients and methods: It is a retrospective study achieved in the service of Internal Medicine of Aristide Le Dantec teaching hospital of Dakar between January 2005 and December 2016 in patients suffering from rheumatoid arthritis. We specified for every patient the predictive data of severity of the rheumatoid arthritis. Results: Four hundred and three patients have been gathered (39 men and 364 women), with the mean age of 45.8 years. An active tobacco addiction was noticed in 10 patients. The diagnostic delay was on average of 72 months. Characteristic articular deformations were noticed in 215 patients (53.3%). They were correlated to male (p = 0.038), to age (p = 0.001) and to the activity of the rheumatoid arthritis (p = 0.0445). Systemic manifestations have been observed in 213 cases (52.9%), particularly anemia (50.8%). They were correlated to the anti-CCP antibodies (p = 0.047). The ESR was increased at the first hour in 84.4% of cases (median: 43 mm; extreme: 1and 160). CRP was elevated in 63.71% of cases (median of 12 mg/l; extreme: 1 and 384). The rheumatoid factor was positive in 57.6% of the cases. The anti-CCP antibodies were present in 89.2% of the cases. Articular erosions were objectified in all cases. A DAS 28 superior to 5.1 was noticed in 71% of cases. Conclusion: The rheumatoid arthritis was severe in our study.
Prognostic Aspects of Lupus Nephritis at Aristide Le Dantec University Hospital in Dakar  [PDF]
Mbengue Mansour, Faye Maria, Cissé Mouhamadou Moustapha, Lemrabott Tall Ahmed, Fall Khodia, Keita Alex, Faye Moustapha, Ba Bakary, Diagne Seynabou, Keita Niakhaleen, Ba Mamadou Aw, Dieng Ameth, Motula Latou Lot, Niang Abdou, Diouf Boucar, Ka El Hadji Fary
Open Journal of Nephrology (OJNeph) , 2018, DOI: 10.4236/ojneph.2018.84014
Abstract: Introduction: Kidney injury is common in the course of lupus and affects the functional and vital prognosis. The risk of progression to end-stage renal failure can reach 40% to 60%. Thus we carried out this work for the purpose of an evaluation of the renal and vital prognosis and to deduce the factors of poor prognosis. Patients and method: This was a retrospective, descriptive and analytical study conducted over a period of 10 years from January 1, 2007 to December 31, 2016, performed in the Nephrology Department of Aristide Le Dantec Hospital in Dakar. Patients with lupus nephritis were included. The studied parameters were epidemiological, clinical, paraclinical and progression. We had done a crossover of the patients to look for the factors of poor renal and vital prognosis. Results: Out of 93 cases of lupus patients, 64 were included, a prevalence of 69%. The mean age of the patients was 31.97 ± 10.44 years old. There were 81% women and 19% men, a sex ratio of 0.23. Class III was found in 24 cases (37.5%), Class IV in 20 cases (31.25%), Class V in 15 cases (23.4%), Class II in 4 cases (6.25%) and Class I in 1 case (1.6%). The combination of corticosteroids and immunosuppressants was used in 56.25% of cases. After a follow-up of six months, 19 patients were in complete remission, 21 had resistance and 9 had partial remission. Of the 21 patients who had resistance, 8 were in chronic renal failure. Death was observed in 5 patients and the causes were in 3 patients: pulmonary embolism, bacterial meningitis and pulmonary tuberculosis. The cause of death was unknown in 2 patients. The factors of poor renal prognosis were lymphopenia, the presence of anti-native DNA antibodies, nephrotic syndrome, microscopic hematuria, tubular atrophy and interstitial fibrosis. Risk factors affecting renal survival were the presence of native anti-DNA antibodies, microscopic hematuria, leukocyturia and the presence of a proliferative class. The factors of poor prognosis were renal failure, lymphopenia, nephrotic syndrome, glomerular sclerosis, arteriosclerosis, interstitial infiltration and tubular atrophy. Conclusion: The risk conferred by nephropathy is greater for proliferative glomerulonephritis; it is also correlated with the presence of persistent nephrotic syndrome or severe renal failure.
Multiple Myeloma Secondary to HIV Infection, Revealed by Renal Failure: About a Case  [PDF]
Mbengue Mansour, Cissé Mouhamadou Moustapha, Faye Maria, Lemrabott Tall Ahmed, Fall Khodia, Keita Alex, Faye Moustapha, Ba Bakary, Diagne Seynabou, Keita Niakhaleen, Ba Mamadou Aw, Dieng Ameth, Niang Abdou, Ka El Hadji Fary, Diouf Boucar
Open Journal of Nephrology (OJNeph) , 2019, DOI: 10.4236/ojneph.2019.91002
Abstract: Multiple myeloma is on the list of neoplasia that may be associated with human immunodeficiency virus infection. It is an affection that aggravates the prognosis in these particular patients. We present the case of a patient with multiple myeloma and HIV infection, revealed by renal failure. This was a 59-year-old patient who was received to the Department of nephrology for renal failure associated with severe aregenerative pancytopenia. In etiological investigations, multiple myeloma associated with HIV1 infection was found. The evolution was unfavorable, marked by the death of the patient caused by digestive haemorrhage before the start of antiretroviral treatment and chemotherapy.
Satisfaction of Health Care Users with the Quality of Health Care Services in Senegal: A Multi-Level Approach  [PDF]
Ndiack Fall
Modern Economy (ME) , 2017, DOI: 10.4236/me.2017.89079
Abstract: This paper analyzes the satisfaction of health care users with the quality of health care in the different types of health facilities in Senegal. The data used come from a survey of the Senegalese health system. In this framework, the multi-level approach with three levels of aggregation was used: patients (level 1), health facilities (level 2) and 14 administrative regions (level 3). The estimation results indicate a diversity, on the one hand, between regions, and on the other hand between health facilities. In addition, the individual characteristics of the patients have diverse effects across the levels of aggregation: the significance of most of them differs with respect to the context (e.g., gender, education level, age, smoking status and ownership of health insurance). While the waiting time and the applied rate effects differ slightly in terms of significance, the former influences negatively the satisfaction when waiting time is less than the duration of an appointment of the following day, whereas the level of satisfaction increases with the rate applied on health care.
Michel Foucault and Francophone geography.
Juliet Fall
EspacesTemps.net , 2005,
Abstract: L’enthousiasme pour la pensée et les écrits de Michel Foucault parmi les géographes anglophones s’oppose au manque certain d’enthousiasme, voir de déni total, parmi leurs collègues francophones. Alors que Foucault est cité très largement dans la littérature contemporaine anglophone au sein des sciences sociales, il demeure marginal pour la grande majorité des géographes travaillant et publiant en fran ais. Malgré l’entrevue de Foucault publiée dans la revue Hérodote en 1976 qui paraissait jeter un pont entre les disciplines, les géographes francophones ont peu lu et peu utilisé ses propositions pour les sciences sociales et politiques. De plus, comme les approches politiques en géographie ont eu relativement peu d’écho pour de multiples raisons, les rares travaux existants comme le livre Espace et pouvoir (1978) de Paul Claval ou La géographie a sert, d’abord, à faire la guerre (1976) de Yves Lacoste ne sont pas influencés par les apports de Foucault. Cet article se propose de faire état de la situation par une revue et un examen de la littérature existante, complétée par des entretiens de géographes contemporains. Les uvres choisies reflètent les rares utilisations explicites de Foucault par des géographes francophones. L’accent est mis plus particulièrement sur Pour une géographie du pouvoir , écrit en 1980 par Claude Raffestin, ainsi que sur ses articles plus tardifs sur le territoire et la territorialité. L’analyse propose que cet essai d’adapter un certain nombre des propositions de Foucault au contexte de la géographie a été écarté et ignoré, malgré son grand intérêt, pour un certain nombre de raisons institutionnelles, conceptuelles et personnelles. Suivant la piste de Foucault dans une approche tant épistémologique que sociologique, l’article examine d’autres apports de géographes fréquentant des lieux éloignés des luttes de pouvoir du monde académique fran ais, explorant brièvement le travail de géographes québécois et suisses, fruits d’une nouvelle génération de penseurs francophones. L’auteure propose que de telles approches du politique méritent un public et un débat plus larges, spécifiquement en ce qu’ils sont différents des approches foucaldiennes anglophones qui sombrent souvent dans un moule homogène et totalisant. The enthusiasm for Michel Foucault among Anglo geographers is in stark contrast to the surprising lack of interest among their Francophone counterparts. Despite the seminal interview of 1976 published in Hérodote that appeared to build a bridge between disciplines, Francophone geographers have rarely read and used his work.
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