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Search Results: 1 - 10 of 3686 matches for " Seung-Kyu Seo "
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On the Dynamical Analysis in Aftershock Networks  [PDF]
Woon-Hak Baek, Kyungsik Kim, Ki-Ho Chang, Seung-Kyu Seo, Jun-Ho Lee, Dong-In Lee
Open Journal of Earthquake Research (OJER) , 2018, DOI: 10.4236/ojer.2018.71002
Abstract:
We investigate the dynamical behavior of aftershocks in earthquake networks, and the earthquake network calculated from a time series is constructed by contemplating cell resolution and temporal causality. We attempt to connect an earthquake network using relationship between one main earthquake and its aftershocks from seismic data of California. We mainly examine some topological properties of the earthquake such as the degree distribution, the characteristic path length, the clustering coefficient, and the global efficiency. Our result cannot presently determine the universal scaling exponents in statistical quantities, but the topological properties may be inferred to advance and improve by implementing the method and its technique of networks. Particularly, it may be dealt with a network issue of convenience and of importance in the case how large networks construct in time to proceed on earthquake systems.
Retiform Sertoli-Leydig Cell Tumor of the Ovary  [PDF]
Gyu-Bong Yu, Seung-Kyu Choi, Yun-Dan Kang, Choong-Hak Park
International Journal of Clinical Medicine (IJCM) , 2016, DOI: 10.4236/ijcm.2016.79065
Abstract: Sertoli-Leydig cell tumor of the ovary is a kind of sex cord-stromal tumor, which occurs between teens and twenties with symptoms including abdominal pain and swelling. The incidence rate is infinitely rare comprising less than 0.5% of all ovarian tumor. The average age of “retiform Sertoli-Leydig cell tumor” is 17 years as compared to 25 years for Sertoli-Leydig cell tumors as a group. We have experienced this rare case of retiform Sertoli-Leydig cell tumor in a 25-year-old foreign patient with the complaint of palpable mass on the right lower quadrant and an irregular menstrual period. The patient underwent right salpingo-oophorectomy and tumor stage was FIGO stage 1A. We report with a brief review of literature.
韩国栗疫病抗病品种的遗传变异分析
朴春根,Kim Kyung-hee,Lee Sang-hyun,Lee Seung-kyu
植物保护学报 , 2007,
Abstract: 为了分析韩国栗疫病的抗病品种和感病品种的遗传变异和抗病性的筛选,利用抗病性的快速检测法和RAPD(randomamplifiedpolymorphicDNA)方法对13个栗树品种进行了抗病性检测和RAPD标记分析。抗病性的快速检测选出了5个抗病品种、5个感病品种和3个中度抗病(或中度感病)品种,并且这一结果与该品种的田间表现相一致。利用筛选的12个随机引物,扩增了100个多态性RAPD片段,但未发现与抗病性或感病性相关的特异RAPD片段。聚类分析结果表明,12个品种大致分为抗病、感病和中度抗病(或中度感病)等3个大组,并与抗病性的快速检测结果基本一致。抗病品种"MANSEKI"表现出了相对于12个品种较远的亲缘关系。
Interrelationship of Pyrogenic Polycyclic Aromatic Hydrocarbon (PAH) Contamination in Different Environmental Media
Seung-Kyu Kim,Dong Soo Lee,Won Joon Shim,Un Hyuk Yim,Yong-Seung Shin
Sensors , 2009, DOI: 10.3390/s91209582
Abstract: Interrelationships between pyrogenic polycyclic aromatic hydrocarbons (PAHs) were assessed in air, soil, water, sediment, and tree leaves by using multi-media monitoring data. Concurrent concentration measurements were taken bimonthly for a year for the multi-media at urban and suburban sites. PAH level correlations between air and other media were observed at the urban site but were less clear at the suburban site. Considering a closer PAHs distribution/fate characteristics to soil than suspended solids, contamination in sediment seemed to be governed primarily by that in soil. The partitioning of PAHs in waters could be better accounted for by sorption onto black carbon and dissolved organic carbon.
Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients
Shama D. Ahuja,David Ashkin,Monika Avendano,Rita Banerjee,Melissa Bauer,Jamie N. Bayona,Mercedes C. Becerra,Andrea Benedetti,Marcos Burgos,Rosella Centis,Eward D. Chan,Chen-Yuan Chiang,Helen Cox,Lia D'Ambrosio,Kathy DeRiemer,Nguyen Huy Dung,Donald Enarson,Dennis Falzon,Katherine Flanagan,Jennifer Flood,Maria L. Garcia-Garcia,Neel Gandhi,Reuben M. Granich,Maria G. Hollm-Delgado,Timothy H. Holtz,Michael D. Iseman,Leah G. Jarlsberg,Salmaan Keshavjee,Hye-Ryoun Kim,Won-Jung Koh,Joey Lancaster,Christophe Lange,Wiel C. M. de Lange,Vaira Leimane,Chi Chiu Leung,Jiehui Li,Dick Menzies ,Giovanni B. Migliori,Sergey P. Mishustin,Carole D. Mitnick,Masa Narita,Philly O'Riordan,Madhukar Pai,Domingo Palmero,Seung-kyu Park,Geoffrey Pasvol,Jose Pe?a,Carlos Pérez-Guzmán,Maria I. D. Quelapio,Alfredo Ponce-de-Leon,Vija Riekstina,Jerome Robert,Sarah Royce,H. Simon Schaaf,Kwonjune J. Seung,Lena Shah,Tae Sun Shim,Sonya S. Shin,Yuji Shiraishi,José Sifuentes-Osornio,Giovanni Sotgiu,Matthew J. Strand,Payam Tabarsi,Thelma E. Tupasi,Robert van Altena,Martie Van der Walt,Tjip S. Van der Werf,Mario H. Vargas,Pirett Viiklepp,Janice Westenhouse,Wing Wai Yew,Jae-Joon Yim on behalf of the Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB,Shama D. Ahuja
PLOS Medicine , 2012, DOI: 10.1371/journal.pmed.1001300
Abstract: Background Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB. Methods and Findings Three recent systematic reviews were used to identify studies reporting treatment outcomes of microbiologically confirmed MDR-TB. Study authors were contacted to solicit individual patient data including clinical characteristics, treatment given, and outcomes. Random effects multivariable logistic meta-regression was used to estimate adjusted odds of treatment success. Adequate treatment and outcome data were provided for 9,153 patients with MDR-TB from 32 observational studies. Treatment success, compared to failure/relapse, was associated with use of: later generation quinolones, (adjusted odds ratio [aOR]: 2.5 [95% CI 1.1–6.0]), ofloxacin (aOR: 2.5 [1.6–3.9]), ethionamide or prothionamide (aOR: 1.7 [1.3–2.3]), use of four or more likely effective drugs in the initial intensive phase (aOR: 2.3 [1.3–3.9]), and three or more likely effective drugs in the continuation phase (aOR: 2.7 [1.7–4.1]). Similar results were seen for the association of treatment success compared to failure/relapse or death: later generation quinolones, (aOR: 2.7 [1.7–4.3]), ofloxacin (aOR: 2.3 [1.3–3.8]), ethionamide or prothionamide (aOR: 1.7 [1.4–2.1]), use of four or more likely effective drugs in the initial intensive phase (aOR: 2.7 [1.9–3.9]), and three or more likely effective drugs in the continuation phase (aOR: 4.5 [3.4–6.0]). Conclusions In this individual patient data meta-analysis of observational data, improved MDR-TB treatment success and survival were associated with use of certain fluoroquinolones, ethionamide, or prothionamide, and greater total number of effective drugs. However, randomized trials are urgently needed to optimize MDR-TB treatment. Please see later in the article for the Editors' Summary.
OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Aging Research
Jae-Seong Yang, Hyun-Jun Nam, Mihwa Seo, Seong Kyu Han, Yonghwan Choi, Hong Gil Nam, Seung-Jae Lee, Sanguk Kim
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0023525
Abstract: Background Aging is a fundamental biological process. Characterization of genetic and environmental factors that influence lifespan is a crucial step toward understanding the mechanisms of aging at the organism level. To capture the different effects of genetic and environmental factors on lifespan, appropriate statistical analyses are needed. Methodology/Principal Findings We developed an online application for survival analysis (OASIS) that helps conduct various novel statistical tasks involved in analyzing survival data in a user-friendly manner. OASIS provides standard survival analysis results including Kaplan-Meier estimates and mean/median survival time by taking censored survival data. OASIS also provides various statistical tests including comparison of mean survival time, overall survival curve, and survival rate at specific time point. To visualize survival data, OASIS generates survival and log cumulative hazard plots that enable researchers to easily interpret their experimental results. Furthermore, we provide statistical methods that can analyze variances among survival datasets. In addition, users can analyze proportional effects of risk factors on survival. Conclusions/Significance OASIS provides a platform that is essential to facilitate efficient statistical analyses of survival data in the field of aging research. Web application and a detailed description of algorithms are accessible from http://sbi.postech.ac.kr/oasis.
Evaluation of a malaria antibody enzyme immunoassay for use in blood screening
Oh, Jun Seo;Kim, Jang Su;Lee, Chang Hwan;Nam, Deok Hwa;Kim, Sun Hyung;Park, Dae Won;Lee, Chang Kyu;Lim, Chae Seung;Park, Gil Hong;
Memórias do Instituto Oswaldo Cruz , 2008, DOI: 10.1590/S0074-02762008005000008
Abstract: transfusion-transmitted malaria is rare, but it may produce severe problem in the safety of blood transfusion due to the lack of reliable procedure to evaluate donors potentially exposed to malaria. here, we evaluated a new enzyme-linked immunosorbent assay malaria antibody test (elisa malaria antibody test, diamed, switzerland) to detect antibodies to plasmodium vivax (the indigenous malaria) in the blood samples in the republic of korea (rok). blood samples of four groups were obtained and analyzed; 100 samples from p.vivax infected patients, 35 from recovery patients, 366 from normal healthy individuals, and 325 from domestic travelers of non-endemic areas residents to risky areas of rok. p.vivax antibody levels by elisa were then compared to the results from microscopic examination and polymerase chain reaction (pcr) test. as a result, the elisa malaria antibody test had a clinical sensitivity of 53.0% and a clinical specificity of 94.0% for p.vivax. twenty out of 325 domestic travelers (6.2%) were reactive and 28 cases (8.6%) were doubtful. of the reactive and doubtful cases, only two were confirmed as acute malaria by both microscopy and pcr test. thus we found that the elisa malaria antibody test was insufficiently sensitive for blood screening of p.vivax in rok.
DJ-1 Null Dopaminergic Neuronal Cells Exhibit Defects in Mitochondrial Function and Structure: Involvement of Mitochondrial Complex I Assembly
Jun Young Heo, Ji Hoon Park, Soung Jung Kim, Kang Sik Seo, Jeong Su Han, Sang Hee Lee, Jin Man Kim, Jong Il Park, Seung Kiel Park, Kyu Lim, Byung Doo Hwang, Minho Shong, Gi Ryang Kweon
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0032629
Abstract: DJ-1 is a Parkinson's disease-associated gene whose protein product has a protective role in cellular homeostasis by removing cytosolic reactive oxygen species and maintaining mitochondrial function. However, it is not clear how DJ-1 regulates mitochondrial function and why mitochondrial dysfunction is induced by DJ-1 deficiency. In a previous study we showed that DJ-1 null dopaminergic neuronal cells exhibit defective mitochondrial respiratory chain complex I activity. In the present article we investigated the role of DJ-1 in complex I formation by using blue native-polyacrylamide gel electrophoresis and 2-dimensional gel analysis to assess native complex status. On the basis of these experiments, we concluded that DJ-1 null cells have a defect in the assembly of complex I. Concomitant with abnormal complex I formation, DJ-1 null cells show defective supercomplex formation. It is known that aberrant formation of the supercomplex impairs the flow of electrons through the channels between respiratory chain complexes, resulting in mitochondrial dysfunction. We took two approaches to study these mitochondrial defects. The first approach assessed the structural defect by using both confocal microscopy with MitoTracker staining and electron microscopy. The second approach assessed the functional defect by measuring ATP production, O2 consumption, and mitochondrial membrane potential. Finally, we showed that the assembly defect as well as the structural and functional abnormalities in DJ-1 null cells could be reversed by adenovirus-mediated overexpression of DJ-1, demonstrating the specificity of DJ-1 on these mitochondrial properties. These mitochondrial defects induced by DJ-1mutation may be a pathological mechanism for the degeneration of dopaminergic neurons in Parkinson's disease.
Kinetic Study of Sulfur Dioxide Elimination by Limestone through the Lab Scale Circulating Fluidized Bed Combustor  [PDF]
Dowon Shun, Dal-Hee Bae, In-Kyu Jang, Keon-Hee Park, Seung Kyu Park
Advances in Materials Physics and Chemistry (AMPC) , 2012, DOI: 10.4236/ampc.2012.24B049
Abstract:

Characteristics of sulfur dioxide emission from coal and petroleum coke combustion were examined in a lab scale circulating fluidized bed (CFB) combustor. The rate constant of the first order rate expression for the absorption SO2 on the CaO surface was similar regardless of the origin of the limestone, the particle size and the initial SO2 concentration. However, the total SO2 absorption capacity was different depending on the origin of the limestone. The breakability of the particle which provides new surface for the reaction seems to play a major role in the absorption characteristics.


Working Memory Impairment in Fibromyalgia Patients Associated with Altered Frontoparietal Memory Network
Jeehye Seo, Seong-Ho Kim, Yang-Tae Kim, Hui-jin Song, Jae-jun Lee, Sang-Hyon Kim, Seung Woo Han, Eon Jeong Nam, Seong-Kyu Kim, Hui Joong Lee, Seung-Jae Lee, Yongmin Chang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0037808
Abstract: Background Fibromyalgia (FM) is a disorder characterized by chronic widespread pain and frequently associated with other symptoms. Patients with FM commonly report cognitive complaints, including memory problem. The objective of this study was to investigate the differences in neural correlates of working memory between FM patients and healthy subjects, using functional magnetic resonance imaging (MRI). Methodology/Principal Findings Nineteen FM patients and 22 healthy subjects performed an n-back memory task during MRI scan. Functional MRI data were analyzed using within- and between-group analysis. Both activated and deactivated brain regions during n-back task were evaluated. In addition, to investigate the possible effect of depression and anxiety, group analysis was also performed with depression and anxiety level in terms of Beck depression inventory (BDI) and Beck anxiety inventory (BAI) as a covariate. Between-group analyses, after controlling for depression and anxiety level, revealed that within the working memory network, inferior parietal cortex was strongly associated with the mild (r = 0.309, P = 0.049) and moderate (r = 0.331, P = 0.034) pain ratings. In addition, between-group comparison revealed that within the working memory network, the left DLPFC, right VLPFC, and right inferior parietal cortex were associated with the rating of depression and anxiety? Conclusions/Significance Our results suggest that the working memory deficit found in FM patients may be attributable to differences in neural activation of the frontoparietal memory network and may result from both pain itself and depression and anxiety associated with pain.
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