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Search Results: 1 - 10 of 746 matches for " Serena Stopponi "
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Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition
Andrea Cippitelli, Giuseppe Astarita, Andrea Duranti, Giovanni Caprioli, Massimo Ubaldi, Serena Stopponi, Marsida Kallupi, Gianni Sagratini, Fernando Rodrìguez de Fonseca, Daniele Piomelli, Roberto Ciccocioppo
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0028142
Abstract: Evidence shows that the endocannabinoid system modulates the addictive properties of nicotine. In the present study, we hypothesized that spontaneous withdrawal resulting from removal of chronically implanted transdermal nicotine patches is regulated by the endocannabinoid system. A 7-day nicotine dependence procedure (5.2 mg/rat/day) elicited occurrence of reliable nicotine abstinence symptoms in Wistar rats. Somatic and affective withdrawal signs were observed at 16 and 34 hours following removal of nicotine patches, respectively. Further behavioral manifestations including decrease in locomotor activity and increased weight gain also occurred during withdrawal. Expression of spontaneous nicotine withdrawal was accompanied by fluctuation in levels of the endocannabinoid anandamide (AEA) in several brain structures including the amygdala, the hippocampus, the hypothalamus and the prefrontal cortex. Conversely, levels of 2-arachidonoyl-sn-glycerol were not significantly altered. Pharmacological inhibition of fatty acid amide hydrolase (FAAH), the enzyme responsible for the intracellular degradation of AEA, by URB597 (0.1 and 0.3 mg/kg, i.p.), reduced withdrawal-induced anxiety as assessed by the elevated plus maze test and the shock-probe defensive burying paradigm, but did not prevent the occurrence of somatic signs. Together, the results indicate that pharmacological strategies aimed at enhancing endocannabinoid signaling may offer therapeutic advantages to treat the negative affective state produced by nicotine withdrawal, which is critical for the maintenance of tobacco use.
You Don’t Know Me But Can I Be Your Friend? Accepting Strangers as Friends in Facebook  [PDF]
Serena Leow, Zuoming Wang
Social Networking (SN) , 2019, DOI: 10.4236/sn.2019.81004
Users in social networking sites, such as Facebook, are increasingly receiving friend requests from strangers. This study examines the effects of the Big Five personality traits (Neurotics vs. Extroversion vs. Openness vs. Conscientiousness vs. Agreeableness) and strangers’ gender in affecting Facebook users’ decisions to accept (or ignore) the stranger’s friend request. Results showed that gender of the stranger and the personality match between participant and stranger jointly affect the decision to accept the stranger as friend on Facebook. Most of the participants accepted the stranger’s friend request based on textual cues that were displayed in the friend request message. This finding supported Social Information Processing theory, suggesting that impression formation of the stranger was not constrained to the lack of nonverbal cues online. Moreover, participants were more likely to accept the stranger’s friend request when the participant’s and stranger’s personalities matched. This effect was more pronounced when the stranger was a female. Participants accepted female stranger’s friend request due to the inflated perception of stereotypical female characteristics, which supports the Hyperpersonal Perspective.
The Abusir Drill Core Survey, Egypt
Serena Love
Papers from the Institute of Archaeology , 2001, DOI: 10.5334/pia.158
Questioning the Location of the Old Kingdom Capital of Memphis, Egypt
Serena Love
Papers from the Institute of Archaeology , 2003, DOI: 10.5334/pia.201
Abstract: The capital city of Memphis was ancient Egypt’s oldest and largest city. However, the city’s origin is shrouded in myth. This study challenges five different references to Memphis, from both classical and historical accounts and concludes that Memphis’ boundary should be redefined. These accounts are reviewed to illustrate the confusion amongst early historians and travellers as to the precise location of Memphis and to highlight the association between the capital and the pyramids of the Giza Plateau. For the Old Kingdom, the urban limits of Memphis should not be restricted to the modern mound of Mit Rahina, but rather the boundaries should be expanded to parallel the Old Kingdom pyramids. Recent archaeological investigations, employing sub-surface sampling techniques, have revealed contemporary Old Kingdom occupational debris scattered throughout the entire Memphite region. The inclusion of archaeological material, in combination with the historical records, will create a different interpretation for Egypt’s Old Kingdom capital city.
The Role of Open Web Standards for Website Development Adhering to the One Web Vision
Serena Pastore
International Journal of Engineering and Technology , 2012,
Abstract: Information dissemination is essential for every organization that needs to increase its visibility. This is valid for educational or research institutes and businesses. Websites are actually the usual way to promote information considering that modern websites are web-based systems composed by several software layers implementing different functionalities. Nowadays, a plethora of web –based content management systems (WCMs), commercial and open-source, provide similar capabilities. The paper highlights the trends in modern website development considering actual open web standards and the particular features of the mobile framework. Approaches include responsive web design techniques and custom mobile sites. Web content should be accessible everywhere, anytime and with whatever devices, which means it should be visualized and processed in the same way regardless of the type of device used, the physical location of the user, and the communication network used at the time. Mobile users’ behavior has a great influence on website development, but open web standards should be adopted in web design to ensure a long-term growth towards the era of the Future Internet.
La situazione attuale della letteratura digitale in Germania
Serena Alcione
LEA : Lingue e Letterature d'Oriente e d'Occidente , 2013,
The Ironies of Comparison : Comparative Literature and the Re-Production of Cultural Difference between East and West
Serena Fusco
Trans : Revue de Littérature Générale et Comparée , 2006,
Abstract: La Littérature Comparée en tant que discipline est aujourd’hui reconnue comme fondamentalement eurocentrique et principalement ancrée dans l’étude des grands canons littéraires européens. Malgré cette tradition, la discipline fait actuellement des efforts pour s’ouvrir à des langues, à des littératures et à des cultures non occidentales. Dans cet article, nous essayerons de comprendre certains enjeux de la Littérature Comparée en tant que discipline potentielle de rencontre entre Est et Ouest, en prenant en considération la Chine comme sujet et objet de discussion. Comparative Literature as a discipline is nowadays recognized as fundamentally Eurocentric and prevalently grounded in the study of “high” European literary canons. In spite of this history, it tries to open itself to non-Western languages, literatures and cultures. In this article, I shall attempt to address some of the stakes of Comparative Literature as a field potentially spanning East and West, taking into consideration China as a subject/object of discourse in its relationship to the discipline. En tanto disciplina, a la literatura comparada se le considera fundamentalmente como eurocéntrica, ancrada sobre todo en el estudio de los “grandes” cánones literarios europeos. A pesar de dicha tradición, la disciplina lleva a cabo un esfuerzo para abrirse a lenguas, a literaturas, a culturas no occidentales. En este artículo intentaremos comprender algunos de los alcances de la Literatura Comparada como disciplina a través de la que se pueden encontrar Oriente y Occidente, tomando a China como tema y objeto de discusión.
The Dance of the Dead Rhino: William Kentridge’s Magic Flute
Serena Guarracino
Altre Modernità , 2010,
Abstract: The article offers a reading of the staging of The Magic Flute by visual artist William Kentridge, focusing on his introduction of the rhino in the visual landscape of the opera as symbol for the silenced subject of violence. Operatic tradition has always been concerned with the staging of death, in particular with the death of its female protagonists, and recent scholarship has highlighted the complicity of the genre with the ideology of Western patriarchy and colonial violence. In this light, Kentridge's appropriation stages Mozart's opera as both voice of colonial Europe and place of resistance for the postcolonial artist. Kentridge moves the setting of the opera to colonial Africa, and the Flute becomes haunted with the massacre of the Herero people in South West Africa by the German army led by general von Trotha (1904-1907). The African white rhino, a species under the threat of extinction, works in this work as proxy for the missing corpses of the Herero people; in its being subject to humiliation and ruthless murder, it recalls Judith Butler's recent attempt at a different categorization of human life as both a continuous exposure to violence and what can be mourned after death. With its silence among the powerful sounds of Mozart's opera, the body of the dead, dancing rhino stands at the centre of Kentridge's work, which becomes a ceremony of mourning where the Western canon can be made to "resonate differently" (Trinh T. Minh-ha).
Il "risveglio" della storiografia politico-istituzionale sul regno angioino di Napoli The "awakening" of the political and institutional history on the Angevin kingdom of Naples
Serena Morelli
Reti Medievali Rivista , 2000, DOI: 10.6092/1593-2214/217
Abstract: Il saggio presenta un breve bilancio della storiografia novecentesca sul regno angioino. The essay briefly reassesses the 20th-century historiography about the Angevin reign.
The Necessity of Semantic Technologies in Grid Discovery
Serena Pastore
Journal of Networks , 2008, DOI: 10.4304/jnw.3.4.1-9
Abstract: Service discovery and its automation are some of the key features that a large scale, open distributed system must provide so that clients and users may take advantage of shared resources. Most actual distributed systems are built with several middleware applications developed by using grid and web service technologies that allow an infrastructure to be implemented where users work as if they were in a local system. The paper, starting from the work done within grid projects in which the INAF Institute was involved, examines issues encountered and solutions proposed in the optics of sharing and thus using web resources such as web services in a specific grid system. By guaranteeing the efficient use of such resources, different discovery mechanisms, developed within grid and web service areas, have been evaluated. The results show the necessity of an appropriate resources’ description in terms of the information data model, protocol and search tools that could integrate semantic technologies required for automating the process. Enabling automatic discovery means both the enriching of description with one of the semantic languages that are in constant development (i.e. OWL-S, WSDL-S) and the availability of a mechanism able to interpret and process such information. This work aims at taking advantage of the improvement in semantic technologies to prove the efficacy of this approach in making use of applications that need a grid environment for their execution.
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