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Search Results: 1 - 10 of 1148 matches for " Sei Ogawa "
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Predictors of Comorbid Psychological Symptoms among Patients with Social Anxiety Disorder after Cognitive-Behavioral Therapy  [PDF]
Sei Ogawa, Risa Imai, Masaki Kondo, Toshi A. Furukawa, Tatsuo Akechi
Open Journal of Psychiatry (OJPsych) , 2016, DOI: 10.4236/ojpsych.2016.61012
Abstract: Aim: The present study aimed to examine the predictors of comorbid psychological symptoms in social anxiety disorder (SAD) after cognitive-behavioral therapy (CBT). Methods: One hundred fourteen SAD patients completed manualized group CBT. We examined associations between the personality dimensions of NEO Five Factor Index (NEO-FFI) and the subscales of Symptom Checklist-90 Revised (SCL-90-R) in SAD patients after CBT using multiple regression analysis. Results: High levels of conscientiousness at baseline predicted symptom reduction on 4 SCL-90-R scales, including somatization, obsessive-compulsive, anxiety and global severity index in patients with SAD after CBT. And high levels of agreeableness predicted symptom reduction on 2 SCL-90-R scales, including Hostility and Paranoid Ideation. High levels of openness predicted psychoticism. Conclusion: The present study suggested that high levels of three NEO-FFI dimensions (openness, agreeableness, conscientiousness) might predict comorbid psychological symptoms reduction in SAD patients after CBT. For the purpose of improving comorbid psychological symptoms with SAD patients, it might be useful to pay more attention to these dimensions of NEO-FFI at baseline.
HIGH RESOLUTION SEM OF INTRINSIC MUSCLE FIBERS OF ANTERIOR THIRD RET'S TONGUE
Motoyama,Aracy A.; Watanabe,Ii-sei; Ogawa,Koichi;
International Journal of Morphology , 2003, DOI: 10.4067/S0717-95022003000400006
Abstract: the characteristics of intrinsic muscle fibers in the anterior third of the adult rat tongue were studied employing light microscopy, sem and high-resolution sem (hrsem) methods. for light microscopy, specimens were fixed in bouin's solution and embedded in paraffin. in order to identify the muscle fibers and bundles of collagen fibers, frontal sections were stained with hematoxylin-eosin, azo-carmin and picro-sirius. the results showed that muscle fibers near the lamina propria are fixed with connective tissue, constituting several groups. the bundles of muscle fibers are arranged in longitudinal, vertical and transversal directions. for sem, specimens were fixed in modified karnovsky solution and freeze-fractured in liquid nitrogen revealed the collagen fibers and bundles of muscle fibers located in three-dimensional aspects. the samples treated in naoh solution showed the original location of collagen fibers, constituting complex networks in three-dimensional sem images. under hrsem, fractured specimens in dmso revealed basement membrane of muscle cell containing sponge-like structures and networks of fine collagen fibrils. cytoplasmic organelles, such as mitochondria with cristae mitochondriales and sarcoplasmic reticulum, were cleary seen in three-dimensional hrsem images
HIGH RESOLUTION SEM OF INTRINSIC MUSCLE FIBERS OF ANTERIOR THIRD RET'S TONGUE MEB DE LATA RESOLUCIóN DE LAS FIBRAS DE LOS MúSCULOS INTRíNSICOS DEL TERCIO ANTERIOR DE LA LENGUA DE RATAS
Aracy A. Motoyama,Ii-sei Watanabe,Koichi Ogawa
International Journal of Morphology , 2003,
Abstract: The characteristics of intrinsic muscle fibers in the anterior third of the adult rat tongue were studied employing light microscopy, SEM and high-resolution SEM (HRSEM) methods. For light microscopy, specimens were fixed in Bouin's solution and embedded in paraffin. In order to identify the muscle fibers and bundles of collagen fibers, frontal sections were stained with hematoxylin-eosin, azo-carmin and picro-sirius. The results showed that muscle fibers near the lamina propria are fixed with connective tissue, constituting several groups. The bundles of muscle fibers are arranged in longitudinal, vertical and transversal directions. For SEM, specimens were fixed in modified Karnovsky solution and freeze-fractured in liquid nitrogen revealed the collagen fibers and bundles of muscle fibers located in three-dimensional aspects. The samples treated in NaOH solution showed the original location of collagen fibers, constituting complex networks in three-dimensional SEM images. Under HRSEM, fractured specimens in DMSO revealed basement membrane of muscle cell containing sponge-like structures and networks of fine collagen fibrils. Cytoplasmic organelles, such as mitochondria with cristae mitochondriales and sarcoplasmic reticulum, were cleary seen in three-dimensional HRSEM images SUMMARY: Las características de las fibras musculares del tercio anterior de la lengua de la rata adulta fueron estudiadas em- pleando microscopio de luz, MEB y métodos de alta resolución de MEB (ARMEB). Para la miscroscopía de luz, los especímenes fueron fijados en solución de Bouin e incluidos en parafina. Con el propósito de identificar las fibras musculares y los haces de fibras colágenas, cortes frontales fueron te idos con hematoxilia-eosina, azo-carmin y picro-sirius. Los resultados mostraron que las fibras musculares cerca de la lámina propia están fijos con tejido conectivo, constituyendo varios grupos. Los haces de fibras musculares están dispuestos en direcciones longitudinal, vertical y transversal. Para la MEB, los especímenes fueron fijados en solución de Karnovsky modificada y fracturadas en frío en nitrógeno líquido revelándose las fibras colágenas y fascículos de fibras musculares dispuestas en tres dimensiones. Las muestras tratadas en solución de NaOH mostraron la original localización de las fibras colágenass, constituyendo complejas redes en imágenes tridimensionales de MEB. A través de ARMEB, los especímenes fracturados en DMSO revelaron la membrana basal de la célula muscular conteniendo estructuras tipo esponja y finas redes de fibras colágenas. Organelos c
Interoceptive hypersensitivity and interoceptive exposure in patients with panic disorder: specificity and effectiveness
Kiyoe Lee, Yumiko Noda, Yumi Nakano, Sei Ogawa, Yoshihiro Kinoshita, Tadashi Funayama, Toshiaki A Furukawa
BMC Psychiatry , 2006, DOI: 10.1186/1471-244x-6-32
Abstract: We first performed an exploratory principal factor analysis of all the items contained in the BSQ to obtain meaningful dimensions of interoceptive fears. Next, we examined the correlations between each interoceptive exposure task's degree of similarity to panic attacks and each BSQ factor and then examined whether the BSQ factor scores decreased in comparison with the baseline values when the corresponding exposure tasks were successfully completed by the subjects.The factor analyses revealed four factors, which we named "pseudoneurological fears", "gastrointestinal fears", "cardiorespiratory fears" and "fears of dissociative feelings." Among the nine interoceptive exposure tasks, 'hyperventilation', 'shaking head', 'holding breath' and 'chest breathing' were considered to reproduce pseudoneurological symptoms, 'breathing through a straw' was considered to reproduce gastrointestinal symptoms, and 'spinning' was considered to reproduce both pseudoneurological and dissociative symptoms; none of the interoceptive exercises were found to reproduce cardiorespiratory symptoms. Among each group of patients for whom 'hyperventilation', 'holding breath', 'spinning' or 'chest breathing' was effective, a significant improvement in the BSQ pseudoneurological fears factor scores was observed. On the other hand, no significant difference between the baseline and endpoint values of the BSQ gastrointestinal fears or the BSQ fears of dissociative feelings factor scores were observed among the patients for whom 'spinning' or 'breathing through a straw' was effective.Several interoceptive exposure tasks were particularly effective in reducing pseudoneurological fears. New interoceptive tasks, especially tasks related to cardiorespiratory and dissociative feelings, are needed.Panic disorder is a common but disabling anxiety disorder. The chief defining criteria for panic disorder are recurrent unexpected panic attacks, persistent concern about having an additional attack, and worry abo
Change in quality of life and their predictors in the long-term follow-up after group cognitive behavioral therapy for social anxiety disorder: a prospective cohort study
Norio Watanabe, Toshi A Furukawa, Junwen Chen, Yoshihiro Kinoshita, Yumi Nakano, Sei Ogawa, Tadashi Funayama, Tetsuji Ietsugu, Yumiko Noda
BMC Psychiatry , 2010, DOI: 10.1186/1471-244x-10-81
Abstract: The study aimed to examine, in the long term, what aspects of Quality of Life (QoL) changed among social anxiety disorder (SAD) patients treated with group cognitive behaviour therapy (CBT) and what predictors at baseline were associated with QoL.Outpatients diagnosed with SAD were enrolled into group CBT, and assessed at follow-ups for up to 12 months in a typical clinical setting. QoL was evaluated using the Short Form 36. Various aspects of SAD symptomatology were also assessed. Each of the QoL domains and scores on symptomatology were quantified and compared with those at baseline. Baseline predictors of QoL outcomes at follow-up were investigated.Fifty-seven outpatients were enrolled into group CBT for SAD, 48 completed the whole program, and 44 and 40 completed assessments at the 3-month and 12-month follow-ups, respectively. All aspects of SAD symptomatology and psychological subscales of the QoL showed statistically significant improvement throughout follow-ups for up to 12 months. In terms of social functioning, no statistically significant improvement was observed at either follow-up point except for post-treatment. No consistently significant pre-treatment predictors were observed.After group CBT, SAD symptomatology and some aspects of QoL improved and this improvement was maintained for up to 12 months, but the social functioning domain did not prove any significant change statistically. Considering the limited effects of CBT on QoL, especially for social functioning, more powerful treatments are needed.Social anxiety disorder (SAD), also known as social phobia, is one of the most common psychiatric disorders, with a 12-month and lifetime prevalence of 7% [1] and 12% [2], respectively. SAD typically begins during the early teenage years and has a chronic course [2]. For example, prospective, long-term, naturalistic studies have indicated that only one-third of individuals attain remission from SAD within 8 years [3]. People with SAD are also at great ris
Group cognitive behavior therapy for Japanese patients with social anxiety disorder: preliminary outcomes and their predictors
Junwen Chen, Yumi Nakano, Tetsuji Ietzugu, Sei Ogawa, Tadashi Funayama, Norio Watanabe, Yumiko Noda, Toshi A Furukawa
BMC Psychiatry , 2007, DOI: 10.1186/1471-244x-7-69
Abstract: Fifty-seven outpatients who participated in group CBT for SAD were evaluated using eight self-reported and one clinician-administered questionnaires to measure various aspects of SAD symptomatology at the beginning and at the end of the program. Pre- and post-treatment scores were compared and the magnitude of treatment effect was quantified as well based once on the intention-to-treat (ITT) and once among the completers only. We also examined baseline predictors of the CBT outcomes.Seven patients (12%) did not complete the program. For the ITT sample, the percentage of reduction was 20% to 30% and the pre to post treatment effect sizes ranged from 0.37 to 1.01. Among the completers, the respective figures were 20% to 33% and 0.41 to 1.19. We found no significant pretreatment predictor of the outcomes.Group CBT for SAD is acceptable and can bring about a similar degree of symptom reduction among Japanese patients with SAD as among Western patients.Social anxiety disorder, with life time prevalence over 10% [1], is said to be the most prevalent anxiety disorder in some Western countries. Curiously enough, the reported prevalence of SAD is much lower in East Asian countries and East African countries, where it or related disorders have been believed to be culture-bound [2]. In order to understand this important disorder, Clark and Wells [3], and Rapee and Heimberg [4] have developed cognitive models that focus on its maintenance mechanisms. In the treatment of SAD, a number of studies have provided strong evidence for the use of cognitive behavior therapy (CBT). Five meta-analyses have found large effect sizes ranging from 0.80 to 1.07 for the reduction of social anxiety symptoms [5-8]. Moreover, some researchers also demonstrated that group administered CBT is cost-effective [6] and is associated with lower relapse rates during follow-up period than phenelzine [9]. Recent researches based on the model of Clark and Wells [3] have shown superior outcomes and the effect
Transmission Electron Microscopy Study of the Neonatal Rat Tongue Mucosa Treated with Special Attention to the Bacteriae on the Epithelial Cell Membrane
Picoli,Lara Cristina; Lopes,Ruberval A; Semprini,Marisa; Sala,Miguel Angel; Ogawa,Koichi; Watanabe,Ii-sei;
International Journal of Morphology , 2006, DOI: 10.4067/S0717-95022006000300006
Abstract: the epithelial cell surfaces of neonatal wistar rat tongue mucosa were examined by transmission electron microscopic method. the tissues were fixed by modified karnovksy solution and embedded in spurr resin. thin sections of 90 nm thickness were cut and examined in the jeol 1010 transmission electron microscopy. it was revealed that the queratinized squamous epithelial cells of the tongue mucosa exposed to cadmium presented groupings of numerous bacteriae which are attached to the flat cell membrane surfaces. the coccus and bacillus are attached to the cell membrane in organized rows or at random, as clearly seen in the tem images. at high magnification, the transmission electron microscopic images showed that bacteriae are attached by a fibrillar structures from each other and from epithelial cell membrane and bacteriae. the control group analysis demonstrated that the cell membrane didn′t show the presence of bacteriae
Ultrastructure of the adhesion of bacteria to the epithelial cell membrane of three-day postnatal rat tongue mucosa: a transmission and high-resolution scanning electron microscopic study
Watanabe, Ii-sei;Ogawa, Koichi;Silva, Marcelo Cavenaghi Pereira da;Motoyama, Aracy Akiko;Kado, Eduardo Shigueaki;Lopes, Ruberval Armando;
Brazilian Dental Journal , 2007, DOI: 10.1590/S0103-64402007000400009
Abstract: togue mucosa surface of 3-day postnatal rats was examined under transmission electron microscopy (tem) and high-resolution scanning electron microscopy (hrsem). for hrsem analysis, the specimens were fixed in the same solution for 24 h, postfixed in 2% osmiun tetroxide, critical-point dried and coated with platinum-palladium. for tem analysis, the specimens were fixed using modified karnovsky solution and embedded in spurr resin. the results revealed the presence of numerous microplicae in the membrane surface of keratinized epithelial cells to which groups of bacteria were attached. these bacteria were staphylococcus and coccus organized either in rows or at random, which were visualized in three-dimensional hrsem images. at high magnification, the tem images revealed the adhesion of bacteria to the cell membrane through numerous filamentous structures comprising the glycocalyx. the fine fibrillar structures rising from each bacterium and from cell membrane were clearly seen. these characteristics on bacteria structure may be used for future control or prevention of bacterial diseases and for installation of the oral native flora.
Carbon Dioxide Capture and Utilization for Gas Engine  [PDF]
Takashi Ogawa
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.510064
Abstract:

Sodium glycinate absorption and ethylene carbonate synthesis from a mixture gas of ethylene oxide and carbon dioxide are evaluated as carbon dioxide capture and utilization system for gas engine flue gas. The energy requirement for CO2 capture is estimated at 3.3 GJ/tonne CO2. The ethylene carbonate synthesis utilizes more than 90% of the captured CO2 and supply 2.5 GJ/tonne CO2 of thermal energy, which is 76% of the energy requirement for CO2 capture. The thermal integration of the sodium glycinate absorption and the ethylene carbonate synthesis reduces the energy requirement for CO2 capture from 3.3 GJ/tonne CO2 to 0.8 GJ/tonne CO2. The energy requirement for the CO2 capture is supplied using the steam saturated at 0.78 MPa from the gas engine without its electric power reduction.

Sensitization of catastrophic cognition in cognitive-behavioral therapy for panic disorder
Yumiko Noda, Yumi Nakano, Kiyoe Lee, Sei Ogawa, Yoshihiro Kinoshita, Tadashi Funayama, Norio Watanabe, Junwen Chen, Yuka Noguchi, Miyako Kataoka, Masako Suzuki, Toshi A Furukawa
BMC Psychiatry , 2007, DOI: 10.1186/1471-244x-7-70
Abstract: Of ninety-five outpatients with panic disorder started the group CBT program for treatment of panic disorder, seventy-nine completer were classified as "cognitively sensitized (CS)" or "cognitive responding (CR)" or "no-responder" according to the difference of the Agoraphobic Cognitions Questionnaire score across treatment. We compared the CS and CR patients in terms of their baseline clinical characteristics. Then we assessed the symptomatic and functional changes for both groups.At the start of the CBT program, despite of the same degree of panic disorder severity, CS scored significantly lower on ACQ score than CR. CS also showed significantly lower score on anticipatory anxiety compared to CR. At the end of treatment CS showed significant improvement in severity of panic disorder, although the degree of improvement was smaller than that for CR. Then CS would progressively reduce their agoraphobic fear and avoidance, and would improve their functional impairment up to three month of follow-up.Panic patients who would experience sensitization of their catastrophic cognitions through the CBT treatment could nonetheless gradually improve. They showed a relatively low level of catastrophic cognition and anticipatory anxiety before starting the CBT program. We might conclude that temporary sensitization of catastrophic cognition may be necessary before improvement especially among those with initially low catastrophic body sensation fears and that we need not be concerned too much with temporary increase in catastrophic cognition in the process of CBT for panic disorder.A number of studies have supported the effectiveness of cognitive behavioral therapy (CBT) for panic disorder [1-3]. Several studies also suggested that CBT is effective treatment for panic patients who have failed to respond to adequate pharmacotherapy [4-7].Cognitive model of panic disorder[8] have proposed that panic attacks result from the catastrophic misinterpretation of certain bodily sensation
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