Natural products are mostly considered safe, effective and with fewer side
effects. For testing the natural products for their analgesic potential various in-vivo methods are used including chemical
induced methods and thermal induced method. In the present review article we have
discussedvarious in-vivo paradigms along with their merits and drawbacks. This mini review
will helppharmacologist in performing various analgesic
experiments.

Abstract:
We describe here a one month old female child with several dysmorphic features and with a de novo analphoid supernumerary marker chromosome only in cultured skin fibroblast cells and not in lymphocytes. The marker was characterized as analphoid inversion-duplication 3q25.33-qter by oligo array comparative genomic hybridization (aCGH) and fluorescence in situ hybridization (FISH) studies. The final skin fibroblast karyotype was interpreted as 47,XX,+der(3).ish inv dup(3)(qter-q25.33::q25.33-qter)(subtel 3q+,subtel 3q+) de novo.In addition to the eight reported cases of analphoid inversion-duplication 3q supernumerary marker in the literature, this is yet another case of 3q sSMC with a new breakpoint at 3q25.33 and with varying phenotype as described in the case report. Identification of more and more similar cases of analphoid inversion-duplication 3q marker will help in establishing a better genotype-phenotype correlation. The study further demonstrates that aCGH in conjunction with routine cytogenetics and FISH is very useful in precisely identifying and characterizing a marker chromosome, and more importantly help in providing with an accurate genetic diagnosis and better counseling to the family.Small supernumerary marker chromosomes occur in 0.075% of unselected prenatal cases and in 0.044% of consecutively studied postnatal cases, and majority of them are de novo in origin [1-4]. Phenotype of individuals with de novo sSMC vary from normal to extremely mild or severe, depending on the chromosomal region involved and the euchromatic content present [5-7]. Although a number of reports describe the occurrence of a variety of sSMC for nearly all the chromosomes, the number for each type is not large enough to suggest a good genotype-phenotype correlation for a given sSMC, except for inv dup(15) and inv dup(22) where the phenotypic consequences are well described [6,8-10]. We describe here the phenotype and corresponding molecular cytogenetic results of a child with

Abstract:
An alternative interpretation of a family of weighted Carleson measures is used to characterize -Carleson measures for a class of Hardy-Orlicz spaces admitting a nice weak factorization. As an application, we provide with a characterization of symbols of bounded weighted composition operators and Cesàro-type integral operators from these Hardy-Orlicz spaces to some classical holomorphic function spaces. 1. Introduction Hardy-Orlicz spaces are the generalization of the usual Hardy spaces. We raise the question of characterizing those positive measures defined on the unit ball of such that these spaces embed continuously into the Lebesgue spaces . More precisely, let denote by the Lebesgue measure on and the normalized measure on the unit sphere which is the boundary of . denotes the space of holomorphic functions on . Let be continuous and nondecreasing function from onto itself. That is, is a growth function. The Hardy-Orlicz space is the space of function in such that the functions , defined by satisfy We denote the quantity on the left of the above inequality by or simply when there is no ambiguity. Let us remark that , where denotes the Luxembourg (quasi)-norm defined by Given two growth functions and , we consider the following question. For which positive measures on , the embedding map , is continuous? When and are power functions, such a question has been considered and completely answered in the unit disc and the unit ball in [1–6]. For more general convex growth functions, an attempt to solve the question appears in [7], in the setting of the unit disc where the authors provided with a necessary condition which is not always sufficient and a sufficient condition. The unit ball version of [7] is given in [8]. To be clear at this stage, let us first introduce some usual notations. For any and , let These are the higher dimension analogues of Carleson regions. We take as the power functions, that is, for . Thus, the question is now to characterize those positive measures on the unit ball such that there exists a constant such that We call such measures -Carleson measures for . We give a complete answer for a special class of Hardy-Orlicz spaces with , . For simplicity, we denote this space by . We prove the following result. Theorem 1.1. Let and . Then the following assertions are equivalent. (i)There exists a constant such that for any and , (i)There exists a constant such that To prove the above result, we combine weak-factorization results for Hardy-Orlicz spaces (see [9, 10]) and some equivalent characterizations of weighted Carleson measures

Abstract:
We provide in this note a full characterization of the multiplier algebra of the product Bloch space that is the dual of the Bergman space $A^1(\mathbb D^n)$, where $\mathbb D^n$ is the unit. polydisc.

Abstract:
We introduce another notion of bounded logarithmic mean oscillation in the N-torus and give an equivalent definition in terms of boundedness of multi-parameter paraproducts from the dyadic little BMO of Cotlar-Sadosky to the product BMO of Chang-Fefferman. We also obtain a sufficient condition for the boundedness of iterated commutators with Hilbert transforms betweeen the strong notions of these two spaces.

Abstract:
We prove some Sawyer-type characterizations for multilinear fractional maximal function for the upper triangle case. We also provide some two-weight norm estimates for this operator. As one of the main tools, we use an extension of the usual Carleson Embedding that is an analogue of the P. L. Duren extension of the Carleson Embedding for measures.

Abstract:
Assuming that one of the symbols satisfies an invariant condition, we prove that usual Sarason condition is necessary and sufficient for the Toeplitz products to be bounded on Bergman spaces. We also characterize bounded and invertible Toeplitz products on vector weighted Bergman spaces of the unit polydisc. For our purpose, we will need the notion of B\'ekoll\'e-Bonami weights in one and several parameters.

Abstract:
We define the notion of $\Phi$-Carleson measures where $\Phi$ is either a concave growth function or a convex growth function and provide an equivalent definition. We then characterize $\Phi$-Carleson measures for Bergman-Orlicz spaces, and apply them to characterize multipliers between Bergman-Orlicz spaces.

Abstract:
We study boundedness properties of a class of multiparameter paraproducts on the dual space of the dyadic Hardy space H_d^1(T^N), the dyadic product BMO space BMO_d(T^N). For this, we introduce a notion of logarithmic mean oscillation on the polydisc. We also obtain a result on the boundedness of iterated commutators on BMO([0,1]^2).