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Search Results: 1 - 10 of 461856 matches for " Sayiner A "
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The remaining challenges of pneumococcal disease in adults
E. Ludwig,P. Bonanni,G. Rohde,A. Sayiner
European Respiratory Review , 2012,
Abstract: Pneumococcal disease can be divided into invasive disease, i.e. when bacteria are detected in normally sterile body fluids, and noninvasive disease. Pneumococcal disease occurs more frequently in younger children and older adults. It is estimated that, in 2050, 30.3% of the European population will be ≥65 yrs old, compared with 15.7% in 2000. Preventive medicine, including vaccination, is essential for the promotion of healthy ageing. Uptake rates for influenza vaccination in the elderly are generally low, despite recommendations in many countries. In addition, it has been reported that influenza infections can make people more susceptible to pneumococcal infections. Despite pneumococcal vaccination, case fatality rates for patients hospitalised with invasive pneumococcal disease have remained at around 12% since the 1950s. Even when effective antibiotic therapy is administered, mortality can be high amongst immunocompetent patients in intensive care. Timely and accurate diagnosis of pneumococcal disease and identification of patients at high risk of poor outcome is essential to ensure that adequate treatment, including hospitalisation when necessary, is implemented as early as possible. Improved diagnostic techniques and more efficacious treatments may help to reduce the burden of pneumococcal disease, but preventive measures, such as influenza and pneumococcal vaccination, should be promoted in order to avoid preventable disease, particularly in the elderly.
Primary care physician perceptions on the diagnosis and management of chronic obstructive pulmonary disease in diverse regions of the world
Aisanov Z, Bai CX, Bauerle O, Colodenco FD, Feldman C, Hashimoto S, Jardim J, Lai CKW, Laniado-Laborin R, Nadeau G, Sayiner A, Shim JJ, Tsai YH, Walters RD, Waterer G
International Journal of Chronic Obstructive Pulmonary Disease , 2012, DOI: http://dx.doi.org/10.2147/COPD.S28059
Abstract: imary care physician perceptions on the diagnosis and management of chronic obstructive pulmonary disease in diverse regions of the world Original Research (3009) Total Article Views Authors: Aisanov Z, Bai CX, Bauerle O, Colodenco FD, Feldman C, Hashimoto S, Jardim J, Lai CKW, Laniado-Laborin R, Nadeau G, Sayiner A, Shim JJ, Tsai YH, Walters RD, Waterer G Published Date April 2012 Volume 2012:7 Pages 271 - 282 DOI: http://dx.doi.org/10.2147/COPD.S28059 Received: 08 November 2011 Accepted: 09 December 2011 Published: 05 April 2012 Zaurbek Aisanov1,*, Chunxue Bai2,*, Otto Bauerle3,*, Federico D Colodenco4,*, Charles Feldman5,6,*, Shu Hashimoto7,*, Jose Jardim8,*, Christopher KW Lai9,*, Rafael Laniado-Laborin10,*, Gilbert Nadeau11,*, Abdullah Sayiner12,*, Jae Jeong Shim13,*, Ying Huang Tsai14,*, Richard D Walters11,*, Grant Waterer15,* 1Pulmonology Research Institute, Moscow, Russia; 2Department of Pulmonary Medicine, Fudan University, Shanghai, People's Republic of China; 3Centro Médico de las Américas, Mérida, Yucatán, Mexico; 4Hospital de Rehabilitación Respiratoria "María Ferrer," Buenos Aires, Argentina; 5Department of Internal Medicine, Charlotte Maxeke Johannesburg Hospital, Johannesburg, South Africa; 6Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; 7Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan; 8Federal University of S o Paulo, S o Paulo, Brazil; 9Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, People's Republic of China; 10Faculty of Medicine, Universidad Autónoma de Baja California, Tijuana, Baja California, Mexico; 11Medical Affairs, GlaxoSmithKline, Brentford, UK; 12Department of Chest Diseases, Ege University Medical School, Izmir, Turkey; 13Department of Pulmonology, Guro Hospital, Korea University Medical Center, Seoul, South Korea; 14Department of Respiratory Care Medicine, Chang Gung Memorial Hospital, Chia-Yi, Taiwan; 15School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia *ICON group (International COPD Network), listed in alphabetical order Abstract: Chronic obstructive pulmonary disease (COPD) is a multicomponent disorder that leads to substantial disability, impaired quality of life, and increased mortality. Although the majority of COPD patients are first diagnosed and treated in primary care practices, there is comparatively little information on the management of COPD patients in primary care. A web-based pilot survey was conducted to evaluate the primary care physician's, or general practitioner's (GP's), knowledge, understanding, and management of COPD in twelve territories across the Asia-Pacific region, Africa, eastern Europe, and Latin America, using a 10-minute questionnaire comprising 20 questions and translated into the native language of each participating territory. The questionnaire was administered to a total
The Effects of Epigallocatechin Gallate and N-Acetylcysteine on Mobile Phone-Induced Oxidative Stress in Guinea Pigs
Gorkem Kismali,Elcin Ozgur,Serkan Sayiner,Burcu Alpaslan,Goknur Guler,Nesrin Seyhan,Tevhide Sel
Journal of Animal and Veterinary Advances , 2012,
Abstract: It has been reported that mobile phones induce free radical formation. Epigallocatechin Gallate (EGCG) and N-Acetylcysteine (NAC) were recently found to be potent antioxidants. The present study was carried out to determine the protective effects of antioxidants namely EGCG and NAC against the mobile phone-induced oxidative stress. Three-month-old male Guinea pigs were randomized into 6 groups; sham group, not exposed to mobile phone, NAC group (300 mg kg-1 ip, 7 days), 10 min mobile phone-exposed group with NAC, 10 min mobile phone-exposed group, EGCG group (25 mg kg-1 ip, 7 days) and 10 min mobile phone-exposed group with EGCG. During the exposure external E fields were measured by NARDA EMR 300 and type 8.3 probe. Guinea pigs were exposed to RFR averaged as 11.2±0.5 V m-1 for 10 min/day/7days. Malondialdehyde (MDA, an index of lipid peroxidation) were analysed as markers of oxidative stress. Plasma MDA levels increased in mobile phone exposed guinea pigs while EGCG causes a significant reduction of MDA levels, whereas NAC caused a significant increase in MDA levels. Also, MDA levels in mobile phone exposure group significantly increased with respect to sham exposure group. A number of studies have identified antioxidant species which show antioxidant effect in low-dose and pro-oxidant behaviour in high-dose. The increase of the lipid peroxidation at the treatment dose of NAC in guinea pigs may possibly be due to pro-oxidant behaviour. Besides, this study expressed that mobile phone exposure affect the level of lipid peroxidation of plasma.
The Evaluation of Epigallocatechin Gallate and N-Acetylcysteine on Serum Testosterone Levels in Male Guinea Pigs Expose to Cell Phone Microwave
Gorkem Kismali,Elcin Ozgur,Serkan Sayiner,Burcu Alpaslan,Goknur Guler,Nesrin Seyhan,Tevhide Sel
Journal of Animal and Veterinary Advances , 2012,
Abstract: Recently, there has been a few information on the effects of mobile phone-exposed on reproduction. The aim of this study to determine the effects of antioxidants namely EGCG and NAC on the serum testosteron levels in the cell phone-exposed guinea pigs. Three-months-old male Guinea pigs were randomized into 6 groups; sham group, not exposed to mobile phone, NAC administration group (300 mg kg-1 i.p. during 7 days), 20 min mobile phone-exposed group with NAC administration, 20 min mobile phone-exposed group, EGCG administration group (25 mg kg-1 i.p. during 7 days) and 20 min mobile phone-exposed group with EGCG administration. During the exposure of every guinea pig, external E fields were measured by NARDA EMR 300 and type 8.3 probe. Guinea pigs were exposed to RFR averaged as 11.2±0.5 V m-1 for 20 min a day during 7 days. Serum testosterone levels were analysed by ELISA. The serum testosterone levels were found insignificantly increased in mobile phone-exposed group compared to the control and the other groups (p>0.05). Likewise, the serum testosterone levels were not found significantly different in the N-Acetyl L-Cysteine (NAC) and Epigallocatechin Gallate (EGCG) administrated groups compared to the sham group.
The Spread of Infectious Disease on Network Using Neutrosophic Algebraic Structure  [PDF]
A. Zubairu, A. A. Ibrahim
Open Journal of Discrete Mathematics (OJDM) , 2017, DOI: 10.4236/ojdm.2017.72009
Abstract: Network theory and its associated techniques has tremendous impact in various discipline and research, from computer, engineering, architecture, humanities, social science to system biology. However in recent years epidemiology can be said to utilizes these potentials of network theory more than any other discipline. Graph which has been considered as the processor in network theory has a close relationship with epidemiology that dated as far back as early 1900 [1]. This is because the earliest models of infectious disease transfer were in a form of compartment which defines a graph even though adequate knowledge of mathematical computation and mechanistic behavior is scarce. This paper introduces a new type of disease propagation on network utilizing the potentials of neutrosophic algebraic group structures and graph theory.
A Comparative Investigation of Lead Sulfate and Lead Oxide Sulfate Study of Morphology and Thermal Decomposition  [PDF]
S. A. A. Sajadi
American Journal of Analytical Chemistry (AJAC) , 2011, DOI: 10.4236/ajac.2011.22024
Abstract: The compound lead oxide sulfate PbSO4.PbO was prepared in our laboratory. The Thermal behavior of PbSO4 was studied using techniques of Thermogravimetry under air atmosphere from 25 to 1200°C. The identity of both compounds was confirmed by XRD technique. Results obtained using both techniques support same decomposition stages for this compound. The electron microscopic investigations are made by SEM and TEM. The compound is characterized by XRD and the purity was determined by analytical Methods. Also a series of thermogravimetric analysis is made and the ideal condition is determined to convert this compound to pure lead oxide.
Metal ion-binding properties of L-glutamic acid and L-aspartic acid, a comparative investigation  [PDF]
S. A. A. Sajadi
Natural Science (NS) , 2010, DOI: 10.4236/ns.2010.22013
Abstract: A comparative research has been developed for acidity and stability constants of M(Glu)1, M(Asp)2 and M(Ttr)3 complexes, which have been determined by potentiometric pH titration. Depending on metal ion-binding properties, vital differences in building complex were observed. The present study indicates that in M(Ttr) com-plexes, metal ions are arranged to the carboxyl groups, but in M(Glu) and M(Asp), some metal ions are able to build chelate over amine groups. The results mentioned-above demonstrate that for some M(Glu) and M(Asp) complexes, the stability constants are also largely determined by the affinity of metal ions for amine group. This leads to a kind of selectivity of metal ions, and transfers them through building complexes accompanied with glutamate and aspartate. For heavy metal ions, this building complex helps the absorption and filtration of the blood plasma, and consequently, the excursion of heavy metal ions takes place. This is an important method in micro-dialysis. In this study the different as-pects of stabilization of metal ion complexes regarding to Irving-Williams sequence have been investigated.
Determining the Basaltic Sequence Using Seismic Reflection and Resistivity Methods  [PDF]
A. Alanezi, A. Qadrouh
Open Journal of Geology (OJG) , 2013, DOI: 10.4236/ojg.2013.32B004

This study was carried out in Harat Rahat (south of Almadinah Almonwarah) using seismic reflection and resistivity methods. The main objectives of this study are to determine the extent of the basaltic layer and to define the subsurface faults and fractures that could affect and control the groundwater movement in the study area. A 2D seismic profile was acquired and the result shows that the subsurface in the study area has a major fault. We obtained a well match when the seismic result was compared with drilled wells. As a complementary tool, the resistivity method was applied in order to detect the groundwater level. The results of the resistivity method showed that six distinct layers have been identified. The interpretation of these six layers show that the first three layers, the fourth layer, the fifth layer and the bottom of the section indicated various subsurface structures and lithologies; various basaltic layers, fractured basalt, weathered basement and fresh basaltic layers, respectively. It is obvious that the eventual success of geophysical surveys depend on the combination with other subsurface data sources in order to produce accurate maps.

Equilibria and Stability in Glycine, Tartrate and Tryptophan Complexes, Investigation on Interactions in Cu(II) Binary and Ternary Systems in Aqueous Solution  [PDF]
S. A. A. Sajadi
Open Journal of Inorganic Non-metallic Materials (OJINM) , 2014, DOI: 10.4236/ojinm.2014.41001

The acidity and stability constants of M(Gly)1, M(Ttr)1, and M(Trp)1 M: Cu2+, Cu(Bpy2)2+, and Cu(Phen3)2+ complexes, were determined by potentiometric pH titration. It is shown that the stability of the binary Cu(L), (L: Gly, Ttr, and Trp) complex is determined by the basicity of the carboxylate group on one side and amino group on the other side. It is demonstrated that the equilibrium, Cu(Ha4)2+ + Cu(L) \"\"Cu(Har)(L) + Cu2+, is displacement due to the well known experience that mixed ligand complexes formed by a divalent 3d ion, a heteroaromatic N base and an O donor ligand possess increased stability. The stability constants of the 1:1 complexes formed between Cu2+, Cu(Bpy)2+ or Cu(Phen)2+

Adaptive Fuzzy Sliding Mode Controller for Grid Interface Ocean Wave Energy Conversion  [PDF]
Adel A. A. Elgammal
Journal of Intelligent Learning Systems and Applications (JILSA) , 2014, DOI: 10.4236/jilsa.2014.62006

This paper presents a closed-loop vector control structure based on adaptive Fuzzy Logic Sliding Mode Controller (FL-SMC) for a grid-connected Wave Energy Conversion System (WECS) driven Self-Excited Induction Generator (SEIG). The aim of the developed control method is to automatically tune and optimize the scaling factors and the membership functions of the Fuzzy Logic Controllers (FLC) using Multi-Objective Genetic Algorithms (MOGA) and Multi-Objective Particle Swarm Optimization (MOPSO). Two Pulse Width Modulated voltage source PWM converters with a carrier-based Sinusoidal PWM modulation for both Generator- and Grid-side converters have been connected back to back between the generator terminals and utility grid via common DC link. The indirect vector control scheme is implemented to maintain balance between generated power and power supplied to the grid and maintain the terminal voltage of the generator and the DC bus voltage constant for variable rotor speed and load. Simulation study has been carried out using the MATLAB/Simulink environment to verify the robustness of the power electronics converters and the effectiveness of proposed control method under steady state and transient conditions and also machine parameters mismatches. The proposed control scheme has improved the voltage regulation and the transient performance of the wave energy scheme over a wide range of operating conditions.

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