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Search Results: 1 - 10 of 5875 matches for " Sara Rang "
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Lactobacillus reuteri Maintains a Functional Mucosal Barrier during DSS Treatment Despite Mucus Layer Dysfunction
Johan Dicksved, Olof Schreiber, Ben Willing, Joel Petersson, Sara Rang, Mia Phillipson, Lena Holm, Stefan Roos
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0046399
Abstract: Treatment with the probiotic bacterium Lactobacillus reuteri has been shown to prevent dextran sodium sulfate (DSS)-induced colitis in rats. This is partly due to reduced P-selectin-dependent leukocyte- and platelet-endothelial cell interactions, however, the mechanism behind this protective effect is still unknown. In the present study a combination of culture dependent and molecular based T-RFLP profiling was used to investigate the influence of L. reuteri on the colonic mucosal barrier of DSS treated rats. It was first demonstrated that the two colonic mucus layers of control animals had different bacterial community composition and that fewer bacteria resided in the firmly adherent layer. During DSS induced colitis, the number of bacteria in the inner firmly adherent mucus layer increased and bacterial composition of the two layers no longer differed. In addition, induction of colitis dramatically altered the microbial composition in both firmly and loosely adherent mucus layers. Despite protecting against colitis, treatment with L. reuteri did not improve the integrity of the mucus layer or prevent distortion of the mucus microbiota caused by DSS. However, L. reuteri decreased the bacterial translocation from the intestine to mesenteric lymph nodes during DSS treatment, which might be an important part of the mechanisms by which L. reuteri ameliorates DSS induced colitis.
Tratamento cognitivo-comportamental para o transtorno de panico e agorafobia: uma história de 35 anos
Rangé, Bernard;
Estudos de Psicologia (Campinas) , 2008, DOI: 10.1590/S0103-166X2008000400002
Abstract: this paper describes the evolution of knowledge of cognitive-behavioral treatment of panic disorder and agoraphobia. it is based on contributions by diverse researchers, and it is described as an integrative treatment inasmuch as it combines pharmacological treatment and various types of cognitive and behavioral therapies. it uses cognitive restructuring techniques, interoceptive habituation, techniques for breathing, situational exposure and existential restructuring. the treatment was originally developed for an individual approach, but it was also later used with group treatments. it was conceived as a treatment to be used by therapists working in places where it would not be possible find qualified cognitive-behavioral treatment, in a step-by-step treatment model. results have been most satisfactory with the exception of some interventions such as assertiveness training and muscular relaxation. adaptations were made to cater to these findings.
Probleme mit Modernisierung als Interpretationsrahmen von sozialer Arbeit und Mütterlichkeit‘“ Problems with “Modernisierung als Interpretationsrahmen von sozialer Arbeit und ‘Mütterlichkeit’” (Modernization as Interpretive Structure for Social Work and ‘Motherliness’)
Brita Rang
querelles-net , 2004,
Abstract: Unver ndert ist das bereits 1986 von Christoph Sach e vorgelegte Buch nun ein drittes Mal, allerdings in einem anderen Verlag erschienen. Gegenstand ist die Entstehung der modernen beruflichen Sozialarbeit, die – so die These –, aus einer Verbindung von bürgerlich-kommunaler Wohlfahrtspflege und bürgerlich-konservativer Frauenbewegung hervorging. Deren ethisches Konzept der geistigen Mütterlichkeit‘ habe jedoch von Beginn an in einem Spannungsverh ltnis zur zunehmenden Verberuflichung und Bürokratisierung der sozialen Arbeit im Ersten Weltkrieg und der Weimarer Republik gestanden. Christoph Sach e’s 1986 work has been published for the third time in an unaltered form, albeit with a different publisher. The object of study is the origin of modern occupational social work that—according to the thesis—developed from the alliance of middle-class/municipal welfare work and the middle-class/conservative women’s movement. Their ethical concept of ‘spiritual motherliness’, however, maintained a tense relationship to the increasing bureaucratization of social work and the incorporation thereof as a mode of occupation during World War I and the Weimar Republic.
An enzyme-centric approach for modelling non-linear biological complexity
Chin-Rang Yang
BMC Systems Biology , 2008, DOI: 10.1186/1752-0509-2-70
Abstract: In this paper, we further demonstrate the application of complex enzyme catalytic and regulatory modules to simulate nonlinear network regulatory patterns vs. simple linear conversion model. We learned and validated that it is essential to incorporate prior knowledge from the literature to simulate non-linear biological complexities. The network expandability is demonstrated and validated with the complex amino acid biosynthetic network with multi-regulations. Also, we demonstrated the compatibility of mechanistic models within close species. Furthermore, the eukaryotic protein factory model for insuring steady mRNA production is simulated and the coupling of RNA transcription and splicing is validated by both mathematical simulation and experimental analysis.We demonstrated the importance of modeling complex enzyme catalytic and regulatory mechanisms to further understand nonlinear network regulatory patterns. The simulations presented in this paper reveal how a living system maintains homeostasis and its robustness to continue functioning while facing environmental stresses or genetic mutations.Remarkable advances in the high throughput technologies enable researchers to broaden their research focuses from a single gene/protein to global gene/protein expression profiles. The daunting challenge is how to turn these overwhelmingly data into real information and gain meaningful insights of how the information is processed in a living system. The goal of Systems Biology is to integrate these high throughput data sets through mathematical models that can computationally simulate the complexity of a biological network, explore the design principles during the evolution of a biological circuit to insure its robustness and thereby generate novel, experimentally testable hypotheses. It is the mission in the post-genomic era to understand how all the parts of cells – genes, proteins, and many other molecules – work in concert to create complex living organisms and analyze h
Homotopy Perturbation Method for Solving Moving Boundary and Isoperimetric Problems  [PDF]
Sara Ghaderi
Applied Mathematics (AM) , 2012, DOI: 10.4236/am.2012.35062
Abstract: In this paper, homotopy perturbation method is applied to solve moving boundary and isoperimetric problems. This method does not depend upon a small parameter in the equation. homotopy is constructed with an imbedding parameter p, which is considered as a “small parameter”. Finally, we use combined homotopy perturbation method and Green’s function method for solving second order problems. Some examples are given to illustrate the effectiveness of methods. The results show that these methods provides a powerful mathematical tools for solving problems.
Creativity at the Crossroad Creative Education as Moral Education?  [PDF]
Sara Nosari
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.37B015

The man’s action, thanks to its creative capacities, gave a new order to the reality: the “created reality” does not present simply a different order, but is an authentic transformation. Which criteria had directed this transformation? Which will be the criteria of future transformation? The paper presents two possible ideas about creativity and argues in favor of a creative action educated and directed by an ethical criteria.

Using Figurative Language to Assess the Stage of Acceptance of Learning Disability as a Springboard for Treatment of Students with Learning Disabilities  [PDF]
Sara Givon
Creative Education (CE) , 2013, DOI: 10.4236/ce.2013.46054

In order to examine the emotional and cognitive processes experienced by adolescents with learning disabilities (LD), twenty tenth grade Israeli students were studied over three years. Data gathered through in-depth interviews underwent an axial-coding process, and a grounded theory model was constructed. The findings revealed various coping styles adopted by students throughout the process of accepting the disability. Participants were asked to use figurative language to describe their method of coping with the disability. Participants’ choice of phrase, metaphor or image characterized the phase of their acceptance as well as their coping style. This can be served as an effective tool of detection. Identifying the stage of students’ acceptance and their coping style may promote optimal treatment for students with LD.

Response Surface Optimization of a Solvent Free Production of cis-9, trans-11 and trans-10, cis-12 Isomers of Conjugated Linoleic Acid Using High Linoleic Sunflower Oil  [PDF]
Sara Koohikamali
Food and Nutrition Sciences (FNS) , 2017, DOI: 10.4236/fns.2017.86047
Abstract: The most dominant and beneficial conjugated linoleic acids isomers (CLAs) with miscellaneous biological tasks are 9c11t-C18:2 and 10t12c-C18:2. The problem with most of the commercial CLA produced by non-optimized conventional approaches is the heterogeneity of their isomers and undesirable toxic by-products. In this study, optimization of the isomerization of the fatty acid methyl esters of the high linoleic sunflower oil was investigated through response surface methodology (RSM). The reaction temperature, the concentration of PEG400 and NaOCH3 had positive influence on the total conjugated linoleic acid methyl esters (CLAME) production as response. However, the effect of the polyethylene glycol 400 (PEG400) concentration was more significant on response than those of other factors (p < 0.05). The reaction time and the interactions between the factors had no significant effect on response (p ≥ 0.05). The optimum point for the maximum response of 72.90% (i.e., based on the mass percentage of total fatty acid methyl esters mixture) was at 5% w/w NaOCH3, 1.06% w/w PEG400 and temperature of 140°C.
Reducing the symptomatology of panic disorder: the effects of a yoga program alone and in combination with cognitive behavioral therapy
Camila F. Vorkapic,Bernard Rangé
Frontiers in Psychiatry , 2014, DOI: 10.3389/fpsyt.2014.00177
Abstract: Introduction: Yoga is a holistic system of different mind body practices that can be used to improve mental and physical health. It has been shown to reduce perceived stress and anxiety as well as improve mood and quality of life. Research documenting the therapeutic benefits of yoga has grown progressively for the past decades. Objectives: The primary goal of this study was to investigate the effects of yoga in patients suffering from panic disorder. We aimed at observing the efficacy of yoga techniques on reducing the symptomatology of panic disorder, compared to a combined intervention of yoga and psychotherapy. Method: Twenty subjects previously diagnosed with panic disorder were selected. Subjects were randomly assigned to both experimental groups: Group 1 (G1-Yoga: 10 subjects) attended yoga classes and Group 2 (G2-CBT + Yoga: 10 subjects) participated in a combined intervention of yoga practice followed by a cognitive behavioral therapy session. Subjects were evaluated two times during the study: pre-test and post-test. Psychometric tools included the Beck Anxiety Inventory (BAI), Hamilton Anxiety Rating Scale (HAM-A), The Panic Beliefs Inventory (PBI) and Body Sensations Questionnaire (BSQ). Results: Statistical analysis showed significant reductions in anxiety levels associated with panic disorder, panic-related beliefs and panic-related body sensations both in G1 and G2. However, the combination of yoga and cognitive behavioral therapy (G2) showed even further reductions in all observed parameters (mean values). Conclusion: This study observed significant improvement in panic symptomatology following both the practice of yoga and the combination of yoga and psychotherapy. While contemplative techniques such as yoga promote a general change in dealing with private events, CBT teaches how to modify irrational beliefs and cognitive distortions. This indicates that the techniques might have complemented each other, increasing the intervention efficacy.
Habilidades sociais na agorafobia e fobia social
Levitan, Michelle;Rangé, Bernard;Nardi, Antonio E.;
Psicologia: Teoria e Pesquisa , 2008, DOI: 10.1590/S0102-37722008000100011
Abstract: anxiety disorders are commonly associated to social skills deficits. social phobia is often related to this deficit, while agoraphobia is not considered. the purpose of this review is to investigate the literature on this association. an electronic search was conducted in the following databases: psycinfo, medline and scielo, besides the references of some selected articles. social skills deficit were more frequent in the studies that evaluated the performance of anxious individuals on unstructured tasks. agoraphobia appears to be associated to an assertiveness deficit, although few studies were conducted.
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