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Search Results: 1 - 10 of 206668 matches for " Sandra Rincón "
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Efectos sobre el sistema nervioso central del extracto etanólico y fracciones de Hygrophila tyttha Leonard
Ariza,Sandra Y; Rincón,Javier; Guerrero,Mario F;
Revista Colombiana de Ciencias Químico - Farmacéuticas , 2006,
Abstract: the central nervous effects elicited by the ethanolic extract and the aqueous, chloroformic, methanolic and hexanic fractions obtained from hygrophila tyttha were evaluated in icr mice. to achieve this objective, tests to prove anxiolytic (elevated plus-maze), antidepressant (forced swimming), anticonvulsant (pentylenetetrazol, electroshock), and hypnotic (pentobarbital induced sleep) activity were applied. a bioguided phytochemical study was carried out to determine the most active fractions. according to the high protection scores obtained by the electroshock model (90%) and the activity registered by the elevated plus maze (comparable to diazepam), the chloroformic fraction possibly contains the main active compounds, such as coumarins, flavonoids, steroids and/or terpenoids and saponins, according to the phytochemical analyses. these results support the ethnobotanical use and the therapeutic potential of hygrophila tyttha as a natural source of therapeutic compounds for the treatment of central disorders like anxiety and seizures.
Malassezia yeast species isolated from patients with dermatologic lesions
Rincón,Sandra; Adriana,Celis; Sopó,Leticia; Motta,Adriana; Cepero de García,María Caridad;
Biomédica , 2005,
Abstract: introduction. yeasts of the genus malassezia form a normal component of skin flora, but are also associated with several dermatological disorders. since 1996, the description of new species in this genus have led to new questions about their epidemiology and pathogenicity. objective. herein, the frequency of malassezia species in individuals with pityriasis versicolor, atopic dermatitis, seborrhoeic dermatitis, seborrhoeic dermatitis was compared in hiv patients and healthy individuals. three body sites were selected for examination -head, thorax, and upper and lower extremities. material and methods. the 154 malassezia species were isolated from 112 individuals and grouped as follows: 39 with seborrhoeic dermatitis (20 were hiv-positive patients), 18 with pityriasis versicolor, 18 with atopic dermatitis and 37 without dermatological leisions. hiv patient samples were examined microscopically, and specimens from both patients and healthy subjects were cultured on modified dixon agar medium. subsequently, isolates were identified by macroscopic, microscopic and physiological characteristics. results. the most commonly isolated species were malassezia globosa (37.5%), m. sympodialis (31.3%) and m. furfur (31.3%). malazzerzia globosa predominated in patients with pityriasis versicolor (67%) and in hiv-positive patients with seborrhoeic dermatitis (85%). in non-hiv patients with atopic dermatitis or seborrhoeic dermatitis, m. furfur and m. restricta were isolated in 72% and 26% of the cases, respectively. conclusion. several conclusions were evident. first, malassezia species was present in subjects with and without dermatological pathologies. second, the species frequency in the sampled population differed from frequencies reported from other geographic areas. third, malassezia globosa was involved at high frequency in patients with dermatological pathologies, suggesting a higher pathogenicity of this species. additional studies on each species are recommended to clari
Leishmaniasis Cutánea Diseminada: Reporte de Dos Casos en Santander, Colombia
Rincón,Melvin Y; Silva,Sandra Y; Due?as,Ruby E; López-Jaramillo,Patricio;
Revista de Salud Pública , 2009, DOI: 10.1590/S0124-00642009000100015
Abstract: leishmaniasis is a zoonosis produced by the transmission of the protozoan leishmania caused by the bite of sand-flies from the lutzomya specie. several clinical manifestations present themselves, depending on the infecting strain and the host's immune response; the most frequent variety is localised cutaneous leishmaniasis. atypical forms sometimes develop, such as the diffuse variety, in which the number of ulcers is greater than 10, thereby affecting several body areas requiring special considerations in its diagnosis and management. this article reports two cases of patients from endemic areas of santander suffering from diffuse cutaneous leishmaniasis produced by the l. panamensis strain. protocols for the active search of this type of case in endemic areas throughout colombia should be implemented.
EFECTOS FARMACOLóGICOS SOBRE EL SISTEMA NERVIOSO CENTRAL INDUCIDOS POR CUMARINA, AISLADA DE Hygrophila tyttha LEONARD
Y. ARIZA,Sandra; RUEDA,Diana C.; RINCóN V.,Javier; L. LINARES,Edgar; GUERRERO,Mario F.;
Vitae , 2007,
Abstract: this study shows the isolation, identification and pharmacological profile on the central nervous system induced by coumarin (1-2 benzpyrone), molecule obtained from hygrophila tyttha leonard (acanthaceae. vulgar name:: "amansamachos"). this specie is a medicinal plant used in colombian traditional medicine for the treatment of anxiety. tests destined to detect possible activity of anxiolytic type (elevated plus maze, marble burying behavior), anticonvulsant (electroshock, pentylenetetrazole), sedative (pentobarbital and ether sleep time) and miorelaxant (wiring test) were used in albino icr mice. according to the positive results in the plus maze, marble burying, electroshock and sleep tests, coumarin (200 mg/kg, po) seems to be a key compound in the pharmacological response induced by hygrophila tyttha. these results may led to the finding of therapeutic alternatives of anxiolytic, anticonvulsant and/or sedative kind from this natural compound.
El sobrepeso es el factor determinante en la presentación de síndrome coronario agudo en adultos jóvenes colombianos Overweight is a determinant factor in the presentation of acute coronary syndrome in colombian young adults
Sandra Y Silva,Melvin Y Rincón,Ruby E Due?as,ángel M Chaves
Revista Colombiana de Cardiología , 2008,
Abstract: Antecedentes: la obesidad es un factor de riesgo para un primer infarto agudo del miocardio. La enfermedad coronaria prematura genera gran impacto socioeconómico por los a os productivos perdidos, lo que hace importante su prevención y tratamiento. Objetivo: evaluar el impacto de la obesidad y otros factores de riesgo convencionales en la presentación de un primer evento coronario agudo en sujetos menores de 50 a os. Métodos: estudio transversal que incluyó pacientes con diagnóstico de síndrome coronario agudo que ingresaron a la institución entre febrero de 2002 y febrero de 2007. La población se dividió en: sujetos menores y mayores de 50 a os, estos últimos seleccionados de manera aleatoria en relación 1:1. La información demográfica, la historia cardiovascular y los factores de riesgo se identificaron en la historia clínica electrónica de la institución y y se corroboraron por vía telefónica. Se empleó la prueba t de student o Wilcoxon rank-sum, según la distribución de las variables. Se realizó un análisis multivariado para determinar los factores de riesgo independientes. Un valor de p < 0,05 se consideró significativo. Resultados: en el período de estudio ingresaron 942 sujetos con diagnóstico de síndrome coronario agudo. 16,1% (152) correspondió a sujetos menores de 50 a os y 90,79% (132) presentaban un primer evento. El promedio de edad en el grupo joven fue 44,3 ± 5,1 y en el grupo mayor (n=132) fue 65,6 ± 8,3 a os. El sobrepeso (OR 1.095; IC 1,01-1,18 p=0,019) y el recuento leucocitario (OR 1,00; IC 1.001-1.005 p=0,001) fueron los dos criterios independientes que predijeron el síndrome coronario agudo en adultos menores de 50 a os, luego de realizar el análisis multivariado no condicional. Los otros factores de riesgo convencionales no mostraron diferencia significativa. Conclusión: el sobrepeso y la inflamación estimada por el conteo leucocitario, fueron los factores de riesgo independientes para la presentación de un primer episodio de síndrome coronario agudo en adultos colombianos menores de 50 a os. Estos resultados confirman la importancia del sobrepeso y la inflamación en los mecanismos fisiopatológicos de la enfermedad cardiovascular en nuestra población. Background: obesity is a risk factor for developing a first myocardial infarct. Premature coronary disease generates a big socioeconomical impact due to productive years loss, which makes important its prevention and treatment. Objective: evaluate the impact of obesity and other conventional risk factors in the presentation of a first acute coronary event in subjects < 50 years. Metho
EFECTOS FARMACOLóGICOS SOBRE EL SISTEMA NERVIOSO CENTRAL INDUCIDOS POR CUMARINA, AISLADA DE Hygrophila tyttha LEONARD PHARMACOLOGICAL EFFECTS ON THE CENTRAL NERVOUS SYSTEM INDUCED BY COUMARIN, ISOLATED FROM Hygrophila tyttha LEONARD
Sandra Y. ARIZA,Diana C. RUEDA,Javier RINCóN V.,Edgar L. LINARES
Vitae , 2007,
Abstract: En este estudio se describe el aislamiento, identificación y perfil farmacológico ejercido sobre el sistema nervioso central por cumarina (1,2-benzopirona), molécula obtenida de la especie Hygrophila tyttha Leonard (Acanthaceae. NV: amansamachos), planta medicinal utilizada popularmente en Colombia con fines tranquilizantes. En ratones albinos ICR se llevaron a cabo pruebas destinadas a detectar posible actividad de tipo ansiolítico (laberinto en cruz elevado, enterramiento de esferas), anticonvulsivante (electroshock, pentilentetrazol), sedante (potenciación de sue o inducido por pentobarbital y éter) y relajante muscular (prueba del alambre). Los resultados muestran que cumarina (200 mg/kg, vo) es un compuesto clave en la actividad farmacológica de esta especie, dados sus efectos positivos en las pruebas de laberinto en cruz, enterramiento de esferas, electroshock y potenciación de sue o. Esto abre la posibilidad de encontrar alternativas terapéuticas de tipo ansiolítico, anticonvulsivante y/o sedante a partir de este compuesto natural. This study shows the isolation, identification and pharmacological profile on the central nervous system induced by coumarin (1-2 benzpyrone), molecule obtained from Hygrophila tyttha Leonard (Acanthaceae. Vulgar name:: "amansamachos"). This specie is a medicinal plant used in Colombian traditional medicine for the treatment of anxiety. Tests destined to detect possible activity of anxiolytic type (elevated plus maze, marble burying behavior), anticonvulsant (electroshock, pentylenetetrazole), sedative (pentobarbital and ether sleep time) and miorelaxant (wiring test) were used in albino ICR mice. According to the positive results in the plus maze, marble burying, electroshock and sleep tests, coumarin (200 mg/kg, po) seems to be a key compound in the pharmacological response induced by Hygrophila tyttha. These results may led to the finding of therapeutic alternatives of anxiolytic, anticonvulsant and/or sedative kind from this natural compound.
NUEVOS SISTEMAS ELECTROQUíMICOS Y FOTOQUíMICOS PARA EL TRATAMIENTO DE AGUAS RESIDUALES Y DE BEBIDA
Sarria,Víctor M; Parra,Sandra; Rincón,ángela G; Pulgarín,César; Torres,Ricardo A;
Revista Colombiana de Química , 2005,
Abstract: with the increasing pressure on a more effective use of water resources, the developpement of appropriate water treatment technologies become more and more important. photochemical and electrochemical oxidation processes have been proposed in recent years as an attractive alternative for the treatment of contaminated water containing anthropogenic substances hardly biodegradable as well as to purify and disinfect drinking waters. the aim of this paper is to present some of our last results demonstrating that electrochemical, photochemical, and the coupling of these processes with biological systems are very promising alternativesfor the improvement of the water quality.
Polysaccharide and extracts from Lentinula edodes: structural features and antiviral activity
Vinicius Rinc?o, Kristie Yamamoto, Nágila Silva Ricardo, Sandra Soares, Luzia Paccola Meirelles, Carlos Nozawa, Rosa Carvalho Linhares
Virology Journal , 2012, DOI: 10.1186/1743-422x-9-37
Abstract: The time-of-addition assay was performed at the times -2, -1, 0, 1 and 2 h of the infection. The virucidal activity and the inhibition of viral adsorption were also evaluated. Plaque assay was used to monitor antiviral activity throughout.The AqE and LeP were more effective when added at 0 h of infection, however, EtOHE was more effective at the times 1 h and 2 h of the infection. AqE, EtOHE and LeP showed low virucidal activity, and the inhibition of viral adsorption was not significant.The results allowed us to conclude that AqE, EtOHE and LeP act on the initial processes of the replication of both strains of virus.Currently, there are a little more than 40 drugs approved for clinical use in the treatment of viral infections [1]. Studies regarding these drugs concentrated on synthetic products up to the end of the 80 s, when natural compounds attracted attention because of their efficacy in the inhibition of viruses important for human and animal health [2]. Natural products are recognized by the pharmaceutical industry because of their wide structural diversity, as well as, variety of pharmacological activities [3]. Amongst the sources of natural compounds, the fungi, especially the basidiomycetes, have stimulated interest from investigators.The basidiomycete Lentinula edodes (Berkeley) Pegler (Lentinus edodes), known as shiitake, an edible mushroom native of the East Asia, is valued for its nutritional and medicinal properties and culinary and industrial applications [4]. Shiitake is the second most popular in the world [5] and in the last decades various compounds with therapeutic properties have been isolated from its mycelium and fruiting body. Some of these have been widely studied, for example, the polysaccharide lentinan which has demonstrated high immunopotentiating and antimetastasic activities [6,7], antitumor activity [8,9], antibacterial, antifungal and antidiabetic activities [10,11], among others. However, few works have examined the antiviral activ
UN ACERCAMIENTO AL DISE?O DE LOS PRODUCTOS CARNICOS BAJOS EN GRASA PARTE I. PRODUCTOS DE PICADO GRUESO
Echeverri Palacio,Luz Miriam; Rincón Alcalá,Sandra Patricia; López Vargas,Humberto; Restrepo Molina,Diego Alonso;
Revista Facultad Nacional de Agronomía, Medellín , 2004,
Abstract: in this study, a formulation and elaboration of a low fat hamburger is presented, using substitutes of this, that besides lowering the caloric content of the product also maintain flavour and texture properties similar to high fat foods. by means of preliminary trials, a standard hamburger with 20% fat was established. nine replacements with 50% of that fat content of the control were evaluated, and by means of sensorial analysis collagen and fiber were selected as the two substitutes that offered the greatest similarity to the previously established standard hamburger. later, an experimental model was designed in which the fat content in the formulations were substituted with percentages of 25, 50 and 75%, conducting five replicas for treatment, in which the following properties were measured: physical-chemical (ph and cra), bromatologicals (protein, fat and humidity), sensorial (flavour, softness and juiciness) and physical texture (hardness, coherence, adhesiveness, elasticity, gumminess, and chewability). all of the data obtained were analysed with an analysis of variance within and among treatments, correlations among answers to the sensorial analyses and those of texture and statistical analyses by means of the contour answer technique, finding with this the fat substitution and replacement percentage that most resembled the parameters of the standard. the judges in the sensorial analysis found that hamburgers with 15% fat presented flavour and juiciness characteristics similar to the standard hamburger independent of the fat substitute used; lower acceptance occurred when the fat percentage descended to values near 5%. for the softness attribute, the judges failed to perceive differences among the different substitutes and the substitution percentage used in the different treatments. texture analysis demonstrated that fat substitutions of fiber of from 25 to 75% yielded in general textural attributes similar to the standard 20% fat hamburger. low correlations
Eficacia y eficiencia de los surfactantes pulmonares en recién nacidos con síndrome de dificultad respiratoria en la unidad de cuidado intensivo neonatal de la Fundación Cardiovascular de Colombia, enero de 2009 - abril de 2011
Gutiérrez-Pereira,Sandra; Prada-Serrano,Silvia; Rincón-álvarez,Laura; Vásquez -Trespalacios,Elsa María;
Revista Gerencia y Políticas de Salud , 2012,
Abstract: to estimate the effectiveness and efficiency of pulmonary surfactants used in infants with respiratory distress syndrome at the colombian cardiovascular foundation, we designed an observational, descriptive study. we analyzed the medical records of newborns hospitalized in this institution between january 2009 and april 2011 and calculated the effectiveness and efficiency indicators for each surfactant. after analyzing aggregate data, we found that the most efficient and effective medication for these patients was survanta. it requires fewer doses per treatment, is more economical, and generates fewer days in the intensive care unit and fewer days of mechanical ventilation. in some cases, however, infasurf was more effective than survanta, caused less extubation failure in infants with low birth weight and fewer complications during treatment.
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