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Search Results: 1 - 10 of 6261 matches for " Samuel Ayokunle Dada "
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Pattern of Upper Gastrointestinal Malignancies as Seen at Endoscopy in Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria  [PDF]
Akande Oladimeji Ajayi, Ebenezer Adekunle Ajayi, Olusoji Abidemi Solomon, Emmanuel Abidemi Omonisi, Samuel Ayokunle Dada
Open Access Library Journal (OALib Journal) , 2016, DOI: 10.4236/oalib.1102731
Aims and Objective: Gastrointestinal malignancies are among the most lethal of all malignancies and are equally notorious for rapidly progressing to advanced stages even in the absence of serious symptoms, thus leading to delayed diagnoses and dismal prognoses. The aim of this study was to determine the prevalence, type, pattern and the histologic characteristics of upper gastrointestinal tumors seen in patients who underwent upper gastrointestinal endoscopy at the Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria. Materials and Methods: This was a three year cross-sectional study involving 78 patients with suspected upper gastrointestinal tumor referred for upper gastrointestinal endoscopy. The study was conducted from January 2011 to December 2013 at the Ekiti State University Teaching Hospital (EKSUTH), Ado-Ekiti, Nigeria. Relevant clinical information such as age, gender, clinical presentations, smoking history, alcohol use, spices, and consumption of opiates were obtained from the patients. Tissue biopsies were taken from the suspected lesions for histological confirmation and characterization. An ethical clearance for this study was obtained from the EKSUTH Ethical and Research committee and all the patients gave written consent for the study. SPSS version 15.0 (SPSS, Inc., Chicago, Illinois, USA) was applied for statistical analysis using the t-test for quantitative variables and χ2 test for qualitative variables. Differences were considered to be statistically significant if P value was less than 0.05. Results: Seventy eight patients were enrolled into this study comprising 22 females and 56 males. The mean age of the population was 55.75 ± 7.20 years. The presenting symptoms were; abdominal mass in 30.8%, abdominal pain in 29.5%, weight loss in 20.5%, dysphagia in 6.4%, haematemesis in 5.1%, melaena in 5.1% and anaemia in 2.6% of the patients. The risk factors identified in the study included; tobacco use or smoking in 25.6%, alcohol in 19.2%, spices in 14.1%, opiates in 3.8% and combination of the above risk factors in 37.2%. 67.9% of the tumors were located in the stomach, 16.7% in the oesophagus and 15.4% in the first part of the duodenum. Of those located in the stomach, 62.3% were in the antrum while 37.7% were in the corpus. Of the oesophageal tumors, 61.5% were in the mid oesophagus, 30.8% were in the lower oesophagus and 7.8% in the upper oesophagus. Tissue histology showed 70.5% were adenocarcinoma, 26.9% were squamous cell carcinoma, 1.3% lymphoma and 1.3% malignant polyp. This was statistically significant p =< 0.05. Conclusion: In view of the fact that upper GI tumors can rapidly progress to advanced stages in the absence of serious symptoms, gastroduodenoscopy is advocated in patients with signs and symptoms of dyspepsia to avoid delayed diagnosis and improve the disease outcome.
Survival of Epidemic, Clinical, Faecal and Recreational Beach Enterococci Strains with Putative Virulence Genes in Marine and Fresh Waters  [PDF]
Asmat Ahmad, Ayokunle Christopher Dada, Gires Usup
Journal of Environmental Protection (JEP) , 2014, DOI: 10.4236/jep.2014.56051

Culturable faecal coliform, epidemic, clinical, faecal and recreational beach enterococci strains possessing putative virulence genes were enumerated over the course of 5 weeks to comparatively assess their persistence in tropical marine and fresh waters. For the clinical and epidemic strains tested, it took 2.38 ± 0.45 days for a 1-log reduction (T90) in marine water. A higher T90 average of 2.51 ± 0.08 was observed for the commensal and environmental strains. Generally, lower T90 values of 2.14 ± 0.26 and 2.15 ± 0.16 days respectively were observed for hospital and community acquired enterococci strains in fresh water mesocosms subjected to tropical ambient temperature. Beach water enterococci and enterococci recovered from faeces of humans survived for up to 20 days and 23 days respectively in fresh and marine waters. The epidemic strain, MMH594, an esp-positive clinical bacteremia isolate that previously caused multiple infections in a hospital ward outbreak fares favourably well in tropical marine and fresh aquatic environments. For enterococci, the decay rate was approximately 13% higher in fresh water than was observed for marine water. On the contrary, for E. coli, the decay rate was approximately 17% lower in fresh water than was observed in marine water. Generally, the whole, the population trends of E. coli and enterococci in fresh and marine water mesocosms did not reveal any evidence of growth. Our findings suggest that potentially pathogenic bacteria can resume active growth after three weeks of being harboured by the reservoir-beach sand and still pose threat to public health.

Packaged water: optimizing local processes for sustainable water delivery in developing nations
Ayokunle C Dada
Globalization and Health , 2011, DOI: 10.1186/1744-8603-7-24
Abstract: The development and use of water portends wide-ranging implications for global survival, security, health and economic development [1]. This demands the need for water issues to be tackled at the highest political level. Consequently, enshrined in international covenants and attested to by world nation's heads are the MDGs, one of which is to halve the proportion of people without sustainable access to portable water and basic sanitation. Today, more than halfway into the deadlines, available figures reveal a large disparity between the expected and the achieved [2]. Following a general paraphrase of the paper in the first section, the gruesome challenges that make achievement of the Millennium Development Goals daunting task in the developing world is described in the second section of this paper. Given the prevailing social and technical cost needed to revitalize or put in place functional public institutions, associated technologies and political will power, it is much undoubted that the standard industrialized world model for delivery of safe drinking water technology may not be affordable in much of the developing world in the foreseeable future [3], the third section suggests packaged water as one of the low cost alternative water provision that could help bridge the gap. As presented in the fourth section of this paper, despite the established role that this drinking water source plays in developing economies and populations, its importance is significantly underestimated. The fifth section highlights a view point that promotes identification of means of improvement rather than disqualification of local provisions and processes in a bid to safeguard public health. Using relevant case studies, it also suggests possible implication of irrational adoption of global policies on water supply access for residents of the developing world. The sixth section concludes.Global attention and efforts have been committed towards making the MDG target for water and Sanitati
Bacteriological Monitoring and Sustainable Management of Beach Water Quality in Malaysia: Problems and Prospects
Ayokunle Christopher Dada,Ahmad Asmat,Usup Gires,Lee Yook Heng
Global Journal of Health Science , 2012, DOI: 10.5539/gjhs.v4n3p126
Abstract: Despite the growing demand of tourism in Malaysia, there are no resolute efforts to develop beaches as tourist destinations. With no incentives to monitor public beaches or to use them in a sustainable manner, they might eventually degenerate in quality as a result of influx of pollutants. This calls for concerted action plans with a view to promoting their sustainable use. The success of such plans is inevitably anchored on the availability of robust quality monitoring schemes. Although significant efforts have been channelled to collation and public disclosure of bacteriological quality data of rivers, beach water monitoring appears left out. This partly explains the dearth of published information related to beach water quality data. As part of an on-going nation-wide surveillance study on the bacteriological quality of recreational beaches, this paper draws on a situation analysis with a view to proffering recommendations that could be adapted for ensuring better beach water quality in Malaysia.
A Pragma-stylistic Analysis of John 3:16
Samuel Ayodele Dada
International Journal of English Linguistics , 2012, DOI: 10.5539/ijel.v2n5p85
Abstract: The data for this study was extracted from the quarterly edition of Our Daily Bread (December 2007, January, February 2008) owing to its graphological layout. The aim of the study is to examine how a major stylistic meaning inducing technique in text composition manifests at the graphological level. John 3:16 in this devotional edition had been re-arranged by Anne Cetas to carry a lot of stylistic significance. The graphological study of this text featured the use of gothic printed letters, re-arrangement (verse paragraph), capitalization, and punctuation marks. Gothic printed and capitalization were graphically fussed together to coin VALENTINE out of this verse of the Scripture. Speech acts, presupposition, inference, implicature and mutual contextual beliefs (MCBs) were used to interpret the meaning of the text. The present analysis has widened the scope of knowledge in the area of stylistics and even that of pragmatics. The graphic representation of John 3:16 and the obvious images contained in it are a clear testimony to the fact that stylistics study and practice could be more than an academic gymnastics. The study validates the thesis which states that both style/form and context contribute in equal measure to any knowledge gained in the course of reading a text.
Oyeyemi Adigun DADA,Ayodele Samuel THOMAS,Oyetola Olusola OWORU
Annals of West University of Timi?oara : Series of Biology , 2012,
Abstract: Compost application in form of pre-planting incorporation limits nutrient use efficiency in upland rice propagation. Supplying nutrients to crop as required enforces realization of yield potential of field crop. Field study was carried out between 2009 and 2010 planting seasons to investigate the response of upland rice cultivars to split application of compost at varying growth phases in derived savannah agro-zone. Cattle dung + maize stover compost was applied in two splits of different growth phases (Pre-planting, tillering and panicle exertion, tillering and booting, panicle exertion and booting) to three upland rice cultivars - NERICAI, NERICA II and Ofada. The study was laid out in randomized complete block design with three replicates. Data were collected on growth, dry matter, nutrient uptake concentrations and grain yield. Data were analyzed using Analysis of Variance (ANOVA) and the significant means were compared with Least Significant Difference (LSD) at p = 0.05. The results showed that compost application at active vegetative periods (Tillering to booting) promoted better LAI (1027.89), number of leaves (23.94) and tillers (5.11). The response of the three upland rice cultivars to varying time of compost application revealed that split application of compost had significant effect on yield components of upland rice cultivars. Uptake concentration of N (11.49mg/kg) and P (8.65mg/kg) were significantly highest in rice field fertilized at panicle exertion and booting growth.
Effect Of Garcinia kola seed meal on egg quality of the north african Catfish (Clarias gariepinus) (Burchell, 1822) Broodstock
AA Dada
African Journal of Food, Agriculture, Nutrition and Development , 2012,
Abstract: Study was undertaken to evaluate the effects of G. kola (Bitter kola) powder on egg quality in African catfish, C. gariepinus broodstocks. Catfish broodstocks (mean weight, 911.25 ± 1.77 g) were randomly distributed into concrete tanks (2 x 2 x 1.2 m) at ten fish/tank in triplicates. Five diets with 40 % crude protein containing 0, 50, 100, 150 and 200 g kg-1 G. kola seed powder in the feed were formulated and added to the tanks to give 3 % of body weight per day. Fecundity, Percentage fertilization, percentage hatchability and egg size (diameter) of C. gariepinus were investigated. The results of the study show that G. kola seed powder affects the fecundity, percentage hatchability and percentage survival of C. gariepinus larval. The fish fed 200 g kg-1 G. kola seed powder had higher oocyte diameter but not significantly different (p<0.05) from those of the fish fed the other diets. However, the egg diameter was largest in the group of fish fed diet 200 g kg-1 G. kola seed powder and this had negative effect on the fertilization of the eggs. Significantly higher (p<0.05) percentage fertilization and percentage hatchability were recorded for the fish fed diet of 150 g kg-1 G. kola seed powder than for the fish fed the alternative diets. The results showed that as the inclusion level of G. kola seed powder increased, the percentage egg fertilization increased, except when the fish were fed diet of 200 g kg- 1 G. kola seed powder where a sharp decrease was recorded. Survival of larval ranged from 88 % to 100 % and was not related to the G. kola seed powder inclusion in the diet. In this study, the larval of the fish fed on diets 150 and 200 g kg-1 G. kola seed powder survived better than the fish fed other supplemented diets. The results suggest that dietary supplementation with G. kola seed powder improved fecundity, hatchability and survival of C. gariepinus larval and has a potential pro-fertility property which can be exploited in fish seed production.
Refractive-status before and after contact lens wear
Dada V
Indian Journal of Ophthalmology , 1981,
Axenfeld-Rieger Syndrome Associated with Congenital Glaucoma and Cytochrome P4501B1 Gene Mutations
Mukesh Tanwar,Tanuj Dada,Rima Dada
Case Reports in Medicine , 2010, DOI: 10.1155/2010/212656
Abstract: Developmental anomalies of the ocular anterior chamber angle may lead to an incomplete development of the structures that form the conventional aqueous outflow pathway. Thus, disorders that present with such dysfunction tend to be associated with glaucoma. Among them, Axenfeld-Rieger (ARS) malformation is a rare clinical entity with an estimated prevalence of one in every 200,000 individuals. The changes in eye morphogenesis in ARS are highly penetrant and are associated with 50% risk of development of glaucoma. Mutations in the cytochrome P4501B1 (CYP1B1) gene have been reported to be associated with primary congenital glaucoma and other forms of glaucoma and mutations in pituitary homeobox 2 (PITX2) gene have been identified in ARS in various studies. This case was negative for PITX2 mutations and compound heterozygote for CYP1B1 mutations. Clinical manifestations of this patient include bilateral elevated intraocular pressure (>40 mmHg) with increased corneal diameter (>14 mm) and corneal opacity. Patient also had iridocorneal adhesions, anteriorly displaced Schwalbe line, anterior insertion of iris, broad nasal bridge and protruding umbilicus. This is the first study from north India reporting CYP1B1 mutations in Axenfeld-Rieger syndrome with bilateral buphthalmos and early onset glaucoma. Result of this study supports the role of CYP1B1 as a causative gene in ASD disorders and its role in oculogenesis.
Gunshot Injuries Involving Musculo-Skeletal System at the Federal Medical Centre, Lagos
AA Dada, BO Awoyomi
Nigerian Journal of Surgery , 2010,
Abstract: Background Gunshot injury (GSI) is a common cause of morbidity and mortality in Nigeria. It is important to study the circumstances and type of injuries for policy formulation to reduce its occurrence. Objective This is to study the demographic profile of GSI patients to assist policy design and reduce its incidence in Nigeria. Method This is a two year prospective study of the pattern of GSI to the musculoskeletal system using observer administered questionnaires at a tertiary health centre in Lagos, Nigeria and a review of the outcome of the treatment of these injuries. Results Fifty four patients with gunshot injury to the musculoskeletal system were studied accounting for (10.3%) of the five hundred and twenty four (524) patients with musculoskeletal injuries treated in the hospital during the period under study. The peak incidencewas in the age group 21-30 years and 41-50 years. The limbs (84.1%) were themost affected parts of the body. Policemen (42.6%) and traders (28.9%) were the most commonly affected people. Violent crime accounted for 85.2% of GSI; Low velocity rifles were the commonest weapon of assault (59.3%). Unfortunately a large number of the patients (44.4%) declined orthodox treatment opting for traditional care. Unintentional shooting occurred in only 11.1%of cases. Conclusion Majority of GSI occurred inmale young people especially policemen and traders. The need for local businessmen to use “cashless” transfer of funds needs to be emphasized. Law enforcement officers need more training and better equipment to effectively confront criminal elements. KeyWords: Gunshot injury, musculo-skeletal system
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