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Search Results: 1 - 10 of 764 matches for " Sahar Soliman "
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Oil and Powder of Spearmint as an Alternative to Sitophilus Oryzae Chemical Control of Wheat Grains
Aly Soliman Derbalah, Sahar Ibrahim Ahmed
Journal of Plant Protection Research , 2011, DOI: 10.2478/v10045-011-0025-9
Abstract: Stored product pests such as Sitophilus Oryzae are a major concern. Alternative and safe control methods for such pests are needed. Therefore, powder and essential oil of Mentha viridis plant were tested under laboratory conditions for their ability to protect wheat grains against the insect S. oryzae. The insect was reared and tested on whole wheat grains. The emergence and adult mortality of the insect S. oryzae were tested. The efficacy of these plant products was evaluated and compared with malathion. The standard compound for controlling S. oryzae has been malathion. The effect of botanical products and malathion on the germination of wheat grains was also evaluated. The chemical components of spearmint oil were also identified using GC-MS analysis. The results showed that, the oil and powder of M. viridis were effective against S. oryzae with the respect to adults mortality. Also, the oil and powdered products of M. viridis significantly reduced the emergence of S. oryzae compared to the control treatment. Spearmint oil and powder do not significantly affect wheat grains germination relative to the control treatment. The efficacy of spearmint against the tested insect was due to the presence of a mixture of bioactive compounds. The results suggested that, spearmint oil and powder are promising as alternatives to chemical control used against S. oryzae in wheat grains. Also, these spearmint products submit a solution of resistance development by insect due to the presence of a lot of bioactive components rather than the single insecticide.
Calcium channel blockade alleviates brain injury induced by long term exposure to an electromagnetic field
Sahar El-Swefy,Hala Soliman,Magdy Huessein
Journal of Applied Biomedicine , 2008,
Abstract: This study aimed to examine the effects of short and long term exposures to 81 mG EMF intensity. It focused on the roles of ROS , Ca2+ and calcium channel blocker (CCB) on the rat brain. Rats were exposed to 81 mG EMF intensity at the mobile phone base station for one and four weeks (2 hr/day, EMF exposed group). Another group of rats was pretreated with CCB (amlodipine 20 mg/ kg) for four weeks and similarly exposed to EMF (EMF + amlodipine group). Sham exposed and amlodipine control groups were used. At the end of the study, Ca2+ as well as pro-inflammatory and oxidative stress markers were measured. Immunohistochemical staining for Bax in brain samples was carried out. Short term exposure evoked a cellular adaptation response. This was evident by a transient increase in brain levels of Ca2+ , glutathione (GSH) and serum tumor necrosis factor alpha (TNFalpha). Long term exposure to EMF was lethal; progressive oxidative damage, and a prolonged increase in the Ca2+ level accompanied by a marked pro-inflammatory reaction (TNFalpha and CRP) were demonstrated. These alterations were ameliorated by pre- and con-comitant treatment with amlodipine. Furthermore, it restored the EMF induced apoptosis in brain to near normal. In conclusion, EMF is a stressor agent that induces an imbalance between ROS generation and antioxidant defense response. Calcium ions may play a pivotal role in enhancing oxidative stress, pro-inflammatory reactions and apoptosis associated with EMF exposure. Therefore calcium channel blockade seems to play a role in brain protection.
Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals
Eiman Mahmoud Ghaniema,Sahar Fathi Ahmed,Irene Raouf Amin,Maryse Soliman Ayoub
Journal of Osteoporosis , 2011, DOI: 10.4061/2011/106380
Abstract: Objective. To find out the presence of osteoporosis in hemophilic arthropathy patients and its correlation with clinical severity and serum levels of magnesium, copper, and zinc. Methods. Joint score, functional assessment score, bone densitometry, and serum magnesium, copper and zinc were done in twenty male hemophilic arthropathy patients and twenty controls. Results. There was highly significant lower Z scores of lumbar spine and neck of femur in patients versus controls (<0.011). Z score of neck of femur correlated negatively with total joint score (=0.013) and functional assessment score (=0.011). Serum levels of copper and zinc correlated positively with Z score of neck of femur (=0.004, =0.001, resp.). Conclusion. Osteoporosis represents a frequent concomitant observation in hemophiliacs. Screening of young hemophiliacs for osteoporosis is recommended with measuring serum levels of magnesium, copper, and zinc for better management of the disease.
Association between Anthropometric Parameters and Cardio-Metabolic Disease Risk Factors Among Obese Children and Adolescents
Nayera E Hassan,Sahar A El-Masry,Nadia L Soliman,Mona M El-Batran
Macedonian Journal of Medical Sciences , 2012,
Abstract: Background: Childhood obesity increases risk for developing cardio-metabolic diseases. Objectives: to investigate the relation of some anthropometric parameters with cardio-metabolic disease risk factors in obese children and adolescents.Subjects and Methods: Cross sectional study, comprised of 139 obese pupils; aged 8 to 16 years (classified to 3 age groups). Each pupil underwent complete physical examination, anthropometric and laboratory assessment (fasting blood sugar and lipid profile).Results: Boys had significantly higher values of abdominal skin fold thickness in the age groups II and III and in central adiposity, waist circumference, waist/hip ratio and sub scapular skin fold thickness in adolescents. For boys, fasting blood sugar correlated with most of the anthropometric measurements in young age, and with skinfold thickness in the three age groups. While lipid profile correlated with skinfold thickness particularly at subscapular area in the age groups I and II. For girls, none of the parameters under study showed any significant correlation except subscapular skinfold thickness which had significant correlations with lipid profile in age groups I and II.Conclusion: Skin fold thickness particularly subscapular; is important indicator for cardio-metabolic complications in obese children of both sexes. Obese boys are more liable to cardio-metabolic complications.
Different Techniques For Body Composition Assessment
Nayera E. Hassan,Sahar A. El-Masry,Nadia L. Soliman,Mona M. EL-Batran
Journal of Medical Sciences , 2008,
Abstract: The inter-relationships and alter nativity of body composition variables derived from simple anthropometry [BMI and Skin Folds (SFs) prediction equations] and Bioelectrical Impedance Analysis (BIA) with dual energy x-ray (DXA) of healthy sixty nine children (37 boys and 32 girls) aged 9.24±1.73 years old were evaluated. The children recruited from public schools in Giza governorate. All of them had BMI ranged between 15th and 85th percentile and were assessed for body composition [percentage body fat (%BF), fat free mass (FFM; kilograms) and body fat mass (BFM; kilograms)] using Slaughter Skin Folds (SFs) prediction equations, BIA and DXA. Repeated ANOVA showed significant differences among the three methods used for the studied variables (p<0.001). In general, Slaughter and BIA are significantly underestimated measured %BF. There is a high correlation between the BMI and both the estimated %BF and BFM (r = 0.67-0.91 for boys and r = 0.87 to 0.97 for the girls). Partial correlation among the estimated % BF derived from the three different methods in both genders revealed a high significant correlations between the estimated %BF derived from DXA and Slaughter equations (r = 0.76 for boys and 0.97 for girls). While the correlation between the estimated %BF derived from DXA and BIA was 0.77 for boys in contrast to girls where it is low significant correlation (r = 0.387). Results suggest that BIA has limited utility in estimating body composition, where as BMI and SFs seem to be more useful in estimating body composition. In conclusion all methods are significantly under estimated body fatness as determined by DXA and the various methods are not interchangeable.
Evaluation of Osteoporosis in Hemophilic Arthropathy Patients: Correlation with Disease Severity and Serum Trace Minerals
Eiman Mahmoud Ghaniema,Sahar Fathi Ahmed,Irene Raouf Amin,Maryse Soliman Ayoub
Journal of Osteoporosis , 2011, DOI: 10.4061/2011/106380
Abstract: Objective. To find out the presence of osteoporosis in hemophilic arthropathy patients and its correlation with clinical severity and serum levels of magnesium, copper, and zinc. Methods. Joint score, functional assessment score, bone densitometry, and serum magnesium, copper and zinc were done in twenty male hemophilic arthropathy patients and twenty controls. Results. There was highly significant lower Z scores of lumbar spine and neck of femur in patients versus controls ( ). Z score of neck of femur correlated negatively with total joint score ( ) and functional assessment score ( ). Serum levels of copper and zinc correlated positively with Z score of neck of femur ( , , resp.). Conclusion. Osteoporosis represents a frequent concomitant observation in hemophiliacs. Screening of young hemophiliacs for osteoporosis is recommended with measuring serum levels of magnesium, copper, and zinc for better management of the disease. 1. Introduction Hemophilia is a coagulation disorder characterized by acute hemorrhages into the musculoskeletal system leading eventually to arthropathy and disability [1]. Deficiency of factor VIII (Hemophilia A) accounts for 85% of cases and 15% are due to factor IX deficiency (Hemophilia B). They are both inherited as x-linked recessive disorder [2]. Hemoarthrosis occurs in 75%–90% of patients with hemophilia. The most common target joints are knee, ankle, and elbow [3]. Acute bleeding increases the pressure in the synovial cavity and bone marrow which leads to severe pain and possible osteonecrosis or a pseudotumoral mass. Intra-articular bleeding produces a direct chemical effect on synovium, cartilage, and bone. Overtime, the blood becomes deposited in the form of hemosiderin in these tissues. Recurrent hyperemia of the joint in the growing child causes juxta articular osteoporosis and overgrowth of the epiphysis. About 50% of patients with hemophilia develop permanent joint deformities [4]. Patients with severe hemophilia may be at risk for developing reduced bone density in childhood and adolescence for a number of reasons as arthropathy and joint deformities result in prolonged immobilization and reduced physical activity which predisposes them for osteoporosis. This can lead to increasing tendency of bone fragility and fractures in patients after trivial trauma [5]. Osteoporosis is a multifactorial disease with particular considerations to calcium, magnesium (Mg), and other trace elements as copper (Cu) and zinc (Zn), as they are essential in bone metabolism as cofactors for specific enzymes for optimal bone matrix
Aliskiren Augments the Activities of Anti-Oxidant Enzymes in Liver Homogenates of DOCA Salt-Induced Hypertensive Rats  [PDF]
Sahar Kamal
Advances in Enzyme Research (AER) , 2014, DOI: 10.4236/aer.2014.22010
Abstract: Hypertension is a serious problem that is recently thought to be associated with damaging effects on target organs partially via oxidative stress. On the other hand, there is accumulating literature describing some sort of therapeutic interaction between antioxidant enzymes in vital organs and hypertension. Therefore, the aim of this study is to investigate the possible effect of a direct renin inhibitor, aliskiren, used in treatment of hypertension via renin-angiotensin-aldosterone system (RAAS), on selected anti-oxidant enzymes in hepatic homogenates in DOCA salt-induced hypertesnive albino rats. Thirty male wister albino rats were assigned randomly into 3 groups (n = 10/ group). Group 1 received no treatement and serves as control. Group 2 received 0.5% carboxymethylcellulose sodium ip as a solvent of aliskiren, as a direct renin inhibitor (DRI). Group 3 received aliskiren 100 mg/kg/day ip for 4 weeks through gastric tube. Systolic blood pressure (SBP) was measured every week and its mean was recorded at the end of the study. Superoxide dismutase (SOD) enzyme in RBCs lysates, activities of catalase (CAT) and glutathione peroxidase enzymes and thiobarbituric acid reactive substance (TBARS), as a marker of lipid peroxidation, in hepatic homogenates were measured at the end of the study. DRI produced a marked reduction in mean SBP of hypertensive rats. It also significantly (p < 0.05) increased the activities of measured anti-oxidant enzymes while it significantly (p < 0.05) reduced TBARS in liver homogenates. These results indicated that renin possesses an oxidative effect in the liver in hypertensive rats. Aliskiren, in addition to its powerful anti-hypertensive effect, it could induce a great anti-oxidant effect in liver homogenates of DOCA salt-hypertensive rats.
The Contributions of Building Information Modelling to Sustainable Construction  [PDF]
Sahar Soltani
World Journal of Engineering and Technology (WJET) , 2016, DOI: 10.4236/wjet.2016.42018
Abstract: Global concerns toward environmental issues have induced growing demand for new approaches in the construction because of its considerable impact on the environment and use of natural resources. Through using construction sustainability tools, methods and techniques, a greener design can be applied during various building phases. In this connection, it is argued that the analytical and integrated models applied by Building Information Modelling (BIM) may also facilitate this process to be performed more efficiently. BIM and construction sustainability are quite different initiatives, but both have received much attention in recent years in the architecture, engineering and construction (AEC) industry. A rigorous analysis of the interactions between them implies that a synergy exists which, if properly it is understood that can be helpful to reduce the environmental impacts of the AEC industry. A BIM-based design model can contribute to sustainability through its three main dimensions which are environmental, economic and social. In this paper, by reviewing the existing literature on BIM and construction sustainability and using a matrix to analyze construction sustainability dimensions and BIM functionalities a number of interactions have been discussed. It can be concluded that despite there are many improvements in implementation of BIM in environmental and economic aspects of sustainability, its potential impact on social dimension has not been explicitly explored hence further studies need to be undertaken in this area.
Light and Electron Microscopic Study of the Effect of Orlistat on the Liver of Adult Male Albino Rats and the Possible Protective Role of β-Carotene  [PDF]
Sahar Youssef
Forensic Medicine and Anatomy Research (FMAR) , 2018, DOI: 10.4236/fmar.2018.62003
Abstract: Orlistat is a safe and effective drug to treat obesity by acting as a pancreatic and gastric lipase inhibitor, resulting in reduction in fat absorption. There is also concern that it may be linked with an increased threat of serious hepatic incidents. The present work was carried out to study the effect of orlistat on the histological, immunohistochemical and electron microscopic structure of the liver in the adult male albino rats and the possible protective role of β-carotene administration. Forty adult albino rats were subjected to experiment for two weeks as follows: group 1 (control), group II, each animal received 0.52 mg/kg bw/day β-Carotene, group III, each animal received orlistat 32 mg/kg/day, and group IV received β-Carotene, 1hour before the administration of orlistat at same dose of group II & III. The liver from each animal was dissected out and processed for histological, (light and electron microscopic study). The result of Hep-Par1 for immunohistochemistry was statistically analyzed. The results showed that orlistat treated group displayed variable disturbance of liver architecture, from dilatation, congested central and portal veins, branching of bile ductules, mononuclear cellular infiltration, areas of hemorrhages, cytoplasmic vacuolation and pyknotic nuclei. The most obvious changes were that degenerative changes in hepatocytes led to depletion of glycogen content of hepatocytes. Hep Par-1 revealed a wide area of negative immune expression around the central vein and in some hepatocytes. Other hepatocytes expressed weak reaction. Ultrastructure examination displayed hepatocytes with swollen mitochondria and others with an electron-dense matrix. The combined treatment of β-Carotene and orlistat led to a marked improvement in most of the previously mentioned changes. It was concluded that orlistat-induced hepatic toxicity. Thus, clinicians should cautiously monitor their patients for signs of hepatic dysfunction. Using an antioxidant such as β-Carotene decreased the toxicity of orlistat.
Synthesis, Characterization, Anti-Bacterial and Anti-Fungal Activities of New Quinoxaline 1,4-di-N-Oxide Derivatives  [PDF]
Dalia Hussein Soliman
International Journal of Organic Chemistry (IJOC) , 2013, DOI: 10.4236/ijoc.2013.33A007
Abstract:

A new series of quinoxaline 1,4-di-N-oxides were synthesized and evaluated for their antibacterial and antifungal activities. The best result was demonstrated by 3-amino-N-(4-methoxyphenyl)-2-quinoxalinecarboxamide 1,4-di-N-oxide 4e, MIC (0.24 μg/ml) against Aspergillus fumigatus, and (0.12 μg/ml) against Streptococcus pneumonia.

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