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Search Results: 1 - 10 of 21189 matches for " Sae Kyung Chang "
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A case of hypereosinophilic syndrome presenting with intractable gastric ulcers
Tae Young Park, Chang Hwan Choi, Suh Yoon Yang, In Soo Oh, In-Do Song, Hyun Woong Lee, Hyung Joon Kim, Jae Hyuk Do, Sae Kyung Chang, Ah Ra Cho, Young Joo Cha
World Journal of Gastroenterology , 2009,
Abstract: We report a rare case of hypereosinophilic syndrome (HES) presenting with intractable gastric ulcers. A 71-year-old man was admitted with epigastric pain. Initial endoscopic findings revealed multiple, active gastric ulcers in the gastric antrum. He underwent Helicobacter pylori (H pylori) eradication therapy followed by proton pump inhibitor (PPI) therapy. However, follow-up endoscopy at 4, 6, 10 and 14 mo revealed persistent multiple gastric ulcers without significant improvement. The proportion of his eosinophil count increased to 43% (total count: 7903/mm3). Abdominal-pelvic and chest computed tomography scans showed multiple small nodules in the liver and both lungs. The endoscopic biopsy specimen taken from the gastric antrum revealed prominent eosinophilic infiltration, and the liver biopsy specimen also showed eosinophilic infiltration in the portal tract and sinusoid. A bone marrow biopsy disclosed eosinophilic hyperplasia as well as increased cellularity of 70%. The patient was finally diagnosed with HES involving the stomach, liver, lung, and bone marrow. When gastric ulcers do not improve despite H pylori eradication and prolonged PPI therapy, infiltrative gastric disorders such as HES should be considered.
Interpretable Housing for Freedom of the Body: The Next Generation of Flexible Homes  [PDF]
Kyung Wook Seo, Chang Sung Kim
Journal of Building Construction and Planning Research (JBCPR) , 2013, DOI: 10.4236/jbcpr.2013.13011
Abstract: If we have gone through the first generation of housing design that pursued functional optimization, ergonomics, and circulation efficiency during the last century, now we are living in the second generation where more advanced goals, such as universal design, ubiquitous design, sustainable design, and environment-friendly design, are emphasized. Although this second generation of design focuses upon the wellness of humans in accordance with environment, it still has the attitude that a more precisely designed home can guarantee a better life. What lacks in this approach is the freedom of the body; it needs to make its own choice as to how to use a space. Thus, it is suggested in this paper that what is important in designing a home is to provide alternatives in daily lives so as to make a full exploration of a given space. These alternatives can be made by offering residents an interpretable space where they can figure out space usages and routs in a constantly changing context. Two spatial devices are discussed in depths as a way to realize this interpretable house: room-to-room enfilade and ring spatial structure. By investigating some existing house plans, it is illustrated how they can guarantee the freedom of the body, and thus alternatives for the flexible domestic life.
The Architectural Expression of Space and Form Created by the Light in the Works of Alvaro Siza  [PDF]
Chang Sung Kim, Kyung Wook Seo
Journal of Building Construction and Planning Research (JBCPR) , 2014, DOI: 10.4236/jbcpr.2014.22011
Abstract: The light is an important element which helps people perceive objects. Therefore, it is important for architects to make the light and space be in harmony with each other. In this study, we analyzed the works of Alvaro Siza with a view to understand the conceptual value of the light expressed in his works and his principles in controlling it. According to the results of the study, the Siza’s architecture is not a mere theoretical one trapped inside formality, but is a sensual and experiential one based on the locality. He was willing to use void spaces to invite the light in free-flowing plans, in order to invigorate and extend architectural spatiality to create deeper visual effect. In addition, the refined light in his works helped visitors experience the continuous forms and spaces by their own movements, while using the changes of the light to stimulate the interest of visitors and highlight the sequence of spaces.
Capacity of Strong and Very Strong Gaussian Interference Relay-without-delay Channels
Hyunseok Chang,Sae-Young Chung
Mathematics , 2011,
Abstract: In this paper, we study the interference relay-without-delay channel which is an interference channel with a relay helping the communication. We assume the relay's transmit symbol depends not only on its past received symbols but also on its current received symbol, which is an appropriate model for studying amplify-and-forward type relaying when the overall delay spread is much smaller than the inverse of the bandwidth. For the discrete memoryless interference relay-without-delay channel, we show an outer bound using genie-aided outer bounding. For the Gaussian interference relay-without-delay channel, we define strong and very strong interference relay-without-delay channels and propose an achievable scheme based on instantaneous amplify-and-forward (AF) relaying. We also propose two outer bounds for the strong and very strong cases. Using the proposed achievable scheme and outer bounds, we show that our scheme can achieve the capacity exactly when the relay's transmit power is greater than a certain threshold. This is surprising since the conventional AF relaying is usually only asymptotically optimal, not exactly optimal. The proposed scheme can be useful in many practical scenarios due to its optimality as well as its simplicity.
Cough in the Elderly Population: Relationships with Multiple Comorbidity
Woo-Jung Song, Alyn H. Morice, Min-Hye Kim, Seung-Eun Lee, Eun-Jung Jo, Sang-Min Lee, Ji-Won Han, Tae Hui Kim, Sae-Hoon Kim, Hak-Chul Jang, Ki Woong Kim, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok Chang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0078081
Abstract: Background The epidemiology of cough in the elderly population has not been studied comprehensively. The present study aimed to investigate the epidemiology of cough in a community elderly population, particularly in relation with their comorbidity. Methods A cross-sectional analysis was performed using a baseline dataset from the Korean Longitudinal Study on Health and Aging, a community-based elderly population cohort study. Three types of cough (frequent cough, chronic persistent cough, and nocturnal cough) were defined using questionnaires. Comorbidity was examined using a structured questionnaire. Health-related quality of life was assessed using the Short Form 36 questionnaire. Results The prevalence was 9.3% for frequent cough, 4.6% for chronic persistent cough, and 7.3% for nocturnal cough. In multivariate logistic regression analyses, smoking, asthma and allergic rhinitis were found to be risk factors for cough in the elderly. Interestingly, among comorbidities, constipation and uncontrolled diabetes mellitus (HbA1c ≥ 8%) were also found to have positive associations with elderly cough. In the Short Form 36 scores, chronic persistent cough was independently related to impairment of quality of life, predominantly in the mental component. Conclusions Cough has a high prevalence and is detrimental to quality of life in the elderly. Associations with smoking, asthma and rhinitis confirmed previous findings in younger populations. Previously unrecognised relationships with constipation and uncontrolled diabetes mellitus suggested the multi-faceted nature of cough in the elderly.
An immunohistochemical study of the pancreatic endocrine cells of the ddN mouse.
Hyeung Sik Lee,Jeong Hyun Chang,Sae Kwang Ku
Folia Histochemica et Cytobiologica , 2010, DOI: 10.5603/4191
Abstract: The regional distribution and frequency of the pancreatic endocrine cells in the ddN mouse were studied using specific antisera against insulin, glucagon, somatostatin and human pancreatic polypeptide (hPP). In the pancreatic islets, most of insulin-immunoreactive (IR) cells were located in the central region, and glucagon-, somatostatin and hPP-IR cells were located in the peripheral region regardless of the lobe. In the splenic part, glucagon-IR cells were also located in the central regions, and more numerous somatostatin-IR cells were detected in the central regions as compared with the duo-denal part. hPP-IR cells were restricted to the peripheral regions in both lobes but more numerous cells were detected in the duodenal portion. In the exocrine parenchyma of the splenic lobe, only insulin- and glucagon-IR cells were detected but all four kinds of IR cells were observed in the duodenal portion. In addition, insulin and hPP-IR cells were also demonstrated in the pancreatic duct regions. In conclusion, some strain-dependent characteristic distributional patterns of pancreatic endocrine cells were found in the ddN mouse with somewhat different distributional patterns between the two pancreatic lobes.
Gaussian Relay Channel Capacity to Within a Fixed Number of Bits
Woohyuk Chang,Sae-Young Chung,Yong H. Lee
Mathematics , 2010,
Abstract: In this paper, we show that the capacity of the three-node Gaussian relay channel can be achieved to within 1 and 2 bit/sec/Hz using compress-and-forward and amplify-and-forward relaying, respectively.
The effects of pre-pregnancy body mass index and gestational weight gain on perinatal outcomes in Korean women: a retrospective cohort study
Sae-Kyung Choi, In-Yang Park, Jong-chul Shin
Reproductive Biology and Endocrinology , 2011, DOI: 10.1186/1477-7827-9-6
Abstract: We retrospectively reviewed the medical records of 2,454 women who had received antenatal care at Seoul St. Mary's Hospital from January 2007 to December 2009. We used World Health Organization definitions for Asian populations of underweight (BMI < 18.5), normal (BMI equal or higher 18.5 and < 23), overweight (BMI equal or higher 23 and < 25), and obese (BMI equal or higher 25). We analyzed perinatal outcomes according to the pre-pregnancy BMI and weight gain during pregnancy, and calculated the adjusted odds ratios (ORs) and 95% confidence intervals (CIs) from multiple logistic regression models by considering maternal age, parity, number of fetuses, length of gestation, and medical history.Among obese women, the adjusted ORs for gestational diabetes, hypertensive disorder, and incompetent internal os of cervix were 4.46, 2.53, and 3.70 (95% CI = 2.63-7.59, 1.26-5.07, and 1.50-9.12), respectively, and the adjusted ORs for neonatal complications such as macrosomia and low Apgar score were 2.08 and 1.98 (95% CI = 1.34-3.22 and 1.19-3.29), respectively, compared with normal weight women. However, there was no positive linear association between gestational weight gain and obstetric outcomes. In normal weight women, maternal and neonatal complications were significantly increased with inadequate weight gain during pregnancy (p < 0.0001 and = 0.0180, respectively), and we observed similar results in underweight women (p = 0.0136 and 0.0004, respectively).This study shows that pre-pregnancy overweight and obesity are more closely related to the adverse obstetric outcomes than excess weight gain during pregnancy. In addition, inadequate weight gain during pregnancy can result in significant complications.Obesity has been frequently cited as a health problem in women of childbearing age. A recent report found that 25% of the adult population was obese. The obesity rate has rapidly increased in the general population and in women of childbearing age [1,2]. According to a s
The Efficacy and Safety of Platelet-Rich Plasma and Adipose-Derived Stem Cells: An Update
Jaehoon Choi,Kyung Won Minn,Hak Chang
Archives of Plastic Surgery , 2012, DOI: http://dx.doi.org/10.5999/aps.2012.39.6.585
Abstract: During the past decade, many studies using platelet-rich plasma (PRP) or adipose-derivedstem cells (ASCs) have been conducted in various medical fields, from cardiovascular researchto applications for corneal diseases. Nonetheless, there are several limitations of practicalapplications of PRP and ASCs. Most reports of PRP are anecdotal and few include controlsto determine the specific role of PRP. There is little consensus regarding PRP production andcharacterization. Some have reported the development of an antibody to bovine thrombin,which was the initiator of platelet activation. In the case of ASCs, good manufacturing practicesare needed for the production of clinical-grade human stem cells, and in vitro expansion ofASCs requires approval of the Korea Food and Drug Administration, such that considerableexpense and time are required. Additionally, some have reported that ASCs could have apotential risk of transformation to malignant cells. Therefore, the authors tried to investigatethe latest research on the efficacy and safety of PRP and ASCs and report on the current stateand regulation of these stem cell-based therapies.
Evaluation of Antioxidant and Anti-Inflammatory Effect of Rhododendron brachycarpum Extract Used in Skin Care Product by in Vitro and in Vivo Test  [PDF]
Amal Kumar Ghimeray, Ha Youn Lee, Young Hoon Kim, Eun Kyung Ryu, Moon Sik Chang
Technology and Investment (TI) , 2015, DOI: 10.4236/ti.2015.62011
Abstract: In this study, we aimed to observe the cytotoxicity, antioxidant and anti-inflammatory activity of Rhododendron brachycarpum extract (RbE) in RAW 264.7 macrophage cell in vitro and the anti-inflammatory or soothing effect of RbE formulated cream (Multicalm-RHTM) on experimentally induced acute irritated skin in healthy subjects in vivo. In vitro study revealed that RbE significantly inhibited NO and ROS generation in a dose dependent manner without cytotoxicity. In clinical test, Multicalm-RHTM cream siginificantly reduced the SLS-enduced erythema after D5 compared to that of placebo. Overall, it can be concluded that the RbE is a non-cytotoxic, antioxidant and anti-irritant agent which can be used as a potent functional ingredient in cosmetics. Likewise, the in vivo clinical study shows that Multicalm-RHTM cream which contains 3% RbE can be used as an effective skin soothing agent.
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