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Search Results: 1 - 10 of 403314 matches for " Sabine M Marx "
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Improving epidemic malaria planning, preparedness and response in Southern Africa
Joaquim DaSilva, Brad Garanganga, Vonai Teveredzi, Sabine M Marx, Simon J Mason, Stephen J Connor
Malaria Journal , 2004, DOI: 10.1186/1475-2875-3-37
Abstract: The SADC countries have adopted the Abuja targets for Roll Back Malaria in Africa, which include improved epidemic detection and response, i.e., that 60% of epidemics will be detected within two weeks of onset, and 60% of epidemics will be responded to within two weeks of detection. The SADC countries recognize that to achieve these targets they need improved information on where and when to look for epidemics. The WHO integrated framework for improved early warning and early detection of malaria epidemics has been recognized as a potentially useful tool for epidemic preparedness and response planning. Following evidence of successful adoption and implementation of this approach in Botswana, the SADC countries, the WHO Southern Africa Inter-Country Programme on Malaria Control, and the SADC Drought Monitoring Centre decided to organize a regional meeting where countries could gather to assess their current control status and community vulnerability, consider changes in epidemic risk, and develop a detailed plan of action for the forthcoming 2004–2005 season. The following is a report on the 1st Southern African Regional Epidemic Outlook Forum, which was held in Harare, Zimbabwe, 26th–29th September, 2004.The Southern African region has a long and varied history of malaria control with periodic epidemics occurring [1,2]. These epidemics can be regional in scale, as in 1996 and 1997, or much more focal, affecting specific districts or sub-districts. The countries of the Southern African Development Community are committed to the Abuja Targets for Roll Back Malaria in Africa, and this includes improved detection and response to epidemics [1]. To meet these targets countries are expected to detect 60% of malaria epidemics within two weeks of onset, and respond to 60% of epidemics within two weeks of their detection. The countries recognize that to achieve these targets they need improved information on where epidemics are most likely to occur, and ideally some indicatio
Die rol van Christelike waardes en opvoeding in Verkeersveiligheidsopvoeding
M. Scott,O. Marx
Koers : Bulletin for Christian Scholarship , 1998, DOI: 10.4102/koers.v63i1&2.525
Abstract: The role of Christian values and education in Traffic Safety Education Traffic safety is one of the more important issues in South Africa today, since traffic accidents cause thousands o f unnecessary deaths each year, particularly among the youth. The key variable of traffic safety is to be found in principled education emphasizing religious and life values. A child need to learn that life, also his/her own, is sacred to God and must be safeguarded by following traffic safety rules and regulations. Since traffic safety is dependent on, inter alia, attitudes and religious-cultural values, children must be taught positive attitudes at home and at school. This point o f departure implies that teachers need to have positive attitudes towards Traffic Safety Education, which, in turn, implies Traffic Safety Education as a prerequisite fo r teacher education.
On the singular spectrum for adiabatic quasi-periodic Schr?dinger Operators
M. Marx,H. Najar
Mathematics , 2008,
Abstract: In this paper we study spectral properties of a family of quasi-periodic Schr\"odinger operators on the real line in the adiabatic limit. We assume that the adiabatic iso-energetic curve has a real branch that is extended along the momentum direction. In the energy intervals where this happens, we obtain an asymptotic formula for the Lyapunov exponent and show that the spectrum is purely singular. This result was conjectured and proved in a particular case by Fedotov and Klopp in \cite{FEKL1}.
Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats
Stefan A Mann, Beatrix Versmold, Romy Marx, Sabine Stahlhofen, Irmgard D Dietzel, Rolf Heumann, Richard Berger
Journal of Neuroinflammation , 2008, DOI: 10.1186/1742-2094-5-39
Abstract: To exclude influences from factors released from other cell types purified cultures of oligodendrocyte precursors were exposed to cytokines and/or steroids and allowed to differentiate for further 6 days in culture. Changes in membrane surface were investigated with capacitance recordings and Scanning Ion Conductance Microscopy. Na+- and K+- currents were investigated using whole cell patch clamp recordings. The expression of myelin specific proteins was investigated using western blots and the precursor cells were identified using immunostaining with A2B5 antibodies.Surviving IFN-γ and TNF-α treated cells continued to maintain voltage-activated Na+- and K+ currents characteristic for the immature cells after 6 days in differentiation medium. Corticosterone, dihydrocorticosterone and, most prominently dexamethasone, counteracted the deleterious effects of IFN-γ and TNF-α on cell survival, A2B5-immunostaining and expression of myelin basic protein. The most potent corticosteroid tested, dexamethasone, was shown to counteract cytokine effects on membrane surface extension and capacitance. Furthermore, coapplication of dexamethasone blocked the cytokine-induced downregulation of the inwardly rectifying potassium current in 80% of the precursor cells and restored the cytokine-blocked down-regulation of the voltage activated Na+- and K+ currents during subsequent differentiation.Our results show that treatment of oligodendrocyte precursors with the inflammatory cytokines TNF-α and IFN-γ block the differentiation of oligodendrocyte precursors at the level of the differentiation of the voltage-gated ion currents. Co-treatment with corticosteroids at the time of cytokine application restores to a considerable extent survival and differentiation of oligodendrocytes at the level of morphological, myelin protein as well as ion current maturation suggesting the option for a functional restoration of cytokine-damaged immature oligodendrocytes.Perinatal brain injury is frequently
The Impact of Financial Reward Contingencies on Cognitive Function Profiles in Adult ADHD
Ivo Marx, Cornelia H?pcke, Christoph Berger, Roland Wandschneider, Sabine C. Herpertz
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0067002
Abstract: Objectives Although it is well established that cognitive performance in children with attention-deficit/hyperactivity disorder (ADHD) is affected by reward and that key deficits associated with the disorder may thereby be attenuated or even compensated, this phenomenon in adults with ADHD has thus far not been addressed. Therefore, the aim of the present study was to examine the motivating effect of financial reward on task performance in adults with ADHD by focusing on the domains of executive functioning, attention, time perception, and delay aversion. Methods We examined male and female adults aged 18–40 years with ADHD (n = 38) along with a matched control group (n = 40) using six well-established experimental paradigms. Results Impaired performance in the ADHD group was observed for stop-signal omission errors, n-back accuracy, reaction time variability in the continuous performance task, and time reproduction accuracy, and reward normalized time reproduction accuracy. Furthermore, when rewarded, subjects with ADHD exhibited longer reaction times and fewer false positives in the continuous performance task, which suggests the use of strategies to prevent impulsivity errors. Conclusions Taken together, our results support the existence of both cognitive and motivational mechanisms for the disorder, which is in line with current models of ADHD. Furthermore, our data suggest cognitive strategies of “stopping and thinking” as a possible underlying mechanism for task improvement that seems to be mediated by reward, which highlights the importance of the interaction between motivation and cognition in adult ADHD.
Working conditions, work life and quality of life of the temporary support staff involved with telematic learning
A Marx,M Greeff,M P Koen
Health SA Gesondheid , 2006, DOI: 10.4102/hsag.v11i1.216
Abstract: Transformation in the South African higher educational system compelled residential universities to introduce alternative education such as distance education (Department of Education, 1997:66-67). Opsomming Die transformasie in die Suid-Afrikaanse ho ronderwys-stelsel het residensi le universiteite genoop om alternatiewe onderrig, soos afstandsonderrig, in te stel (Departement van Onderwys, 1997:66-67). *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
Advantages of intranasal vaccination and considerations on device selection
Birkhoff M,Leitz M,Marx D
Indian Journal of Pharmaceutical Sciences , 2009,
Abstract: Oral and Intramuscular vaccination has been considered till date as the ultimate ways, but nasal route offers advantages such as ease of self administration and induction of mucosal as well as systemic immunity. Both liquid and dry powder formulations can be given via intranasal route. A great consideration has to be given while selecting a suitable device for nasal administration since the volume delivered is very low. A number of devices are available based on number of doses to be administered and type of dosage formulation.
Regen, Erdbeben und Klimawandel. Die Katastrophe der unrechtm igen Herrschaft in antiker literarischer Tradition
Sabine Müller
Behemoth : a Journal on Civilisation , 2008,
Abstract: This paper explores the political interpretation of natural disasters in ancient literary tradition. Regarded as divine signs or punishments, a natural phenomenon or disaster is often connected to illegitimate rule. Specifically, the paper will examine the connection between natural disasters and political changes in ancient literature. It will be argued that descriptions of natural disasters often serve either to emphasize or to hide violations of political tradition or continuity of power.
Layers of Identity: Multiple Psychological Senses of Community Within a Community Setting
Brodsky,Anne E; Marx,Christine M;
Psykhe (Santiago) , 2004, DOI: 10.4067/S0718-22282004000200015
Abstract: this article explores psychological sense of community (psoc), a feeling of belonging to, importance of, and identification with a community. in much of the research on psoc, there has been a focus on identifying a single psoc for an individual in a setting. qualitative and quantitative data are used here to investigate the presence and operation of multiple psychological senses of community for individuals. these multiple psocs are explored in two macro, territorial settings and a subcommunity of one of these settings: a job training and education center for underserved women in baltimore city. exploration of multiple psocs at the macro- and subcommunity levels expands our conceptualization of the operation of psoc and has real-life implications for fostering positive outcomes in multicultural communities. ? 2001 john wiley & sons, inc.
Layers of Identity: Multiple Psychological Senses of Community Within a Community Setting Niveles de la Identidad: Múltiples Sentidos Psicológicos de Comunidad en un Entorno Comunitario
Anne E Brodsky,Christine M Marx
Psykhe (Santiago) , 2004,
Abstract: This article explores psychological sense of community (PSOC), a feeling of belonging to, importance of, and identification with a community. In much of the research on PSOC, there has been a focus on identifying a single PSOC for an individual in a setting. Qualitative and quantitative data are used here to investigate the presence and operation of multiple psychological senses of community for individuals. These multiple PSOCs are explored in two macro, territorial settings and a subcommunity of one of these settings: a job training and education center for underserved women in Baltimore City. Exploration of multiple PSOCs at the macro- and subcommunity levels expands our conceptualization of the operation of PSOC and has real-life implications for fostering positive outcomes in multicultural communities. 2001 John Wiley & Sons, Inc. El presente artículo explora el sentido psicológico de comunidad (PSOC), un sentimiento de pertenencia, importancia e identificación con la comunidad. Gran parte de la investigación realizada sobre el PSOC se ha focalizado en identificar un único sentido de comunidad para un individuo en un contexto determinado. Datos cualitativos y cuantitativos son usados aquí para investigar la presencia de múltiples sentidos psicológicos de comunidad para los individuos. Estos múltiples PSOCs son explorados en dos contextos territoriales a nivel macro, y en una subcomunidad de uno de estos contextos: un centro de capacitación laboral y educación para mujeres de escasos recursos en la ciudad de Baltimore. La exploración de múltiples PSOCs en los niveles macro y subcomunitario expande nuestra conceptualización del funcionamiento del PSOC y tiene implicancias en la vida real, para promover resultados positivos en comunidades multiculturales.
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