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Search Results: 1 - 10 of 2269 matches for " Sabine Geiger-Gritsch "
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Introduction of organised mammography screening in Tyrol: results following first year of complete rollout
Willi Oberaigner, Martin Daniaux, Sabine Geiger-Gritsch, Rudolf Knapp, Uwe Siebert, Wolfgang Buchberger
BMC Public Health , 2011, DOI: 10.1186/1471-2458-11-673
Abstract: Working from the results of the pilot phase, we extended the organised mammography system to all counties in Tyrol. All women living in Tyrol and covered by compulsory social insurance were invited for a mammography, in the age group 40-59 annually and in the age group 60-69 biennially. Screening mammography was offered mainly by radiologists in private practice, with further assessment performed at hospitals. Using the screening database, all well-established performance indicators were analysed and compared with accepted/desired levels as per the EU guidelines.From June 2008 to May 2009, 120,440 women were invited. Per 1000 mammograms, 14 women were recalled for further assessment, nine underwent biopsy and four cancer cases were detected. Of invasive breast cancer cases, 32.3% and 68.4% were ≤ 10 mm and ≤ 15 mm in size, respectively, and 79.2% were node-negative. The positive predictive value for further assessment and for biopsy was 25.9% and 39.9%, respectively. Estimated two-year participation rate was 57.0%. In total, 14 interval cancer cases were detected during one year of follow-up; this is 18.4% of the background incidence rate.In Tyrol, Austria, an organised mammography screening program was implemented in a smooth transition from an existing spontaneous screening system and was completely rolled out within a short time. The high level of performance already seen in the pilot phase was maintained after rollout, and improvements resulting from the pilot phase were affirmed after one year of complete rollout.Breast cancer is the leading cause of female cancer death in all industrialised countries (and also worldwide), and the breast is also the leading incident cancer site for females [1]. Therefore, screening methods for breast cancer are of greatest public health importance. A recently published Cochrane Review, which assessed the effect of mammography screening for breast cancer on mortality and morbidity concluded that screening is likely to reduce bre
IgG Apheresis for ABO-incompatible Kidney Transplantation: A Systematic Review Shows Insufficient Evidence on Efficacy and Safety
S. Mathis,R. Winkler,S. Geiger-Gritsch,T. Mittermayr
Transplantationsmedizin , 2010,
Abstract: Organ recipients often have to wait for many years [1]. One effort to increase the number of available donators is crossing the borders of ABO-compatibility. This approach has been followed over the last 4 decades [2-11]. One specific method to enable kidney transplantations classified as incompatible is a selective removal of anti blood group antibodies by a preceding selective immunoadsorption. On the occasion of a suggestion to add the service of selective anti-ABO-IgG immunoadsorption to enable kidney transplantation across ABO borders to the list of generally reimbursed clinical health services in Austria this systematic review revealed the evidence for the use of this technology.A systematic search in medical databases (Medline via Ovid, Embase, The Cochrane Library) and HTA databases was performed and articles were selected according to defined inclusion criteria. Reviewing the literature showed about 100 cases where this health technology was applied reported in 8 studies. Beside promising results, the analysed quality of the published evidence is very low and risk of flawed conclusions is high. According to the evaluation method of GRADE the evidence is too weak to make a well-founded positive recommendation. In particular there are no studies that directly compare patient relevant options (e.g.: Extension of donator programs, acceptance of longer waiting time). To evaluate the net benefit further scientific research is still necessary.
IgG Apheresis for ABO-incompatible Kidney Transplantation: A Systematic Review Shows Insufficient Evidence on Eefficacy and Safety
S. Mathis,R. Winkler,S. Geiger-Gritsch,T. Mittermayr
Transplantationsmedizin , 2010,
Abstract: Organ recipients often have to wait for many years [1]. One effort to increase the number of available donators is crossing the borders of ABO-compatibility. This approach has been followed over the last 4 decades [2-11]. One specific method to enable kidney transplantations classified as incompatible is a selective removal of anti blood group antibodies by a preceding selective immunoadsorption. On the occasion of a suggestion to add the service of selective anti-ABO-IgG immunoadsorption to enable kidney transplantation across ABO borders to the list of generally reimbursed clinical health services in Austria this systematic review revealed the evidence for the use of this technology.A systematic search in medical databases (Medline via Ovid, Embase, The Cochrane Library) and HTA databases was performed and articles were selected according to defined inclusion criteria. Reviewing the literature showed about 100 cases where this health technology was applied reported in 8 studies. Beside promising results, the analysed quality of the published evidence is very low and risk of flawed conclusions is high. According to the evaluation method of GRADE the evidence is too weak to make a well-founded positive recommendation. In particular there are no studies that directly compare patient relevant options (e.g.: Extension of donator programs, acceptance of longer waiting time). To evaluate the net benefit further scientific research is still necessary.
Dimensionality Effects in Dipolar Fluids: A Density Functional Theory Study  [PDF]
Remi Geiger, Sabine H. L. Klapp
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.43A056
Abstract:
Using classical density functional theory (DFT) in a modified mean-field approximation we investigate the fluid phase behavior of quasi-two dimensional dipolar fluids confined to a plane. The particles carry three-dimensional dipole moments and interact via a combination of hard-sphere, van-der-Waals, and dipolar interactions. The DFT predicts complex phase behavior involving first- and second-order isotropic-to-ferroelectric transitions, where the ferroelectric ordering is characterized by global polarization within the plane. We compare this phase behavior, particularly the onset of ferroelectric ordering and the related tri-critical points, with corresponding three-dimensional systems, slab-like systems (with finite extension into the third direction), and true two-dimensional systems with two-dimensional dipole moments.
Morse theory for the Yang-Mills functional via equivariant homotopy theory
U. Gritsch
Mathematics , 2001,
Abstract: In this paper we show the existence of non minimal critical points of the Yang-Mills functional over a certain family of 4-manifolds with generic SU(2)-invariant metrics using Morse and homotopy theoretic methods. These manifolds are acted on fixed point freely by the Lie group SU(2) with quotient a compact Riemann surface of even genus. We use a version of invariant Morse theory for the Yang-Mills functional used by Parker and by Rade.
The Homotopy Type of hyperbolic Monopole Orbit Spaces
Ursula Gritsch
Mathematics , 1999,
Abstract: We prove that the space of gauge equivalence classes of U(1)-invariant connections on some SU(2)-principle bundles over the 4-sphere S^4 is weakly homotopy equivalent to a component of the second loop space of the 2-sphere S^2.
Measurement Quantization Describes Galactic Rotational Velocities, Obviates Dark Matter Conjecture  [PDF]
Jody Geiger
Journal of High Energy Physics, Gravitation and Cosmology (JHEPGC) , 2019, DOI: 10.4236/jhepgc.2019.52028
Abstract: A physical description of the orbital mechanics of stars around a galactic core has proved difficult. Notably, there is insufficient mass to account for observed star velocities. The mystery is one of few in modern science that defy the known laws of physics. It has been conjectured that there is a new form of matter that interacts gravitationally while otherwise remaining undetectable. In this paper we resolve the mystery. The expressions do not modify the known laws of physics, contain no free variables or fitting and are entirely classical in nature. Using the notion of counts of the fundamental measures—length, mass and time—it is shown that measure is bounded. Accounting for this bound and the expansion of space reveal that the conjecture is unnecessary thus resolving the dark matter mystery.
Der kardiogene Schock
Gritsch W,Wiedermann CJ
Journal für Kardiologie , 1998,
Abstract:
Measurement Quantization Unites Classical and Quantum Physics  [PDF]
Jody A. Geiger
Journal of High Energy Physics, Gravitation and Cosmology (JHEPGC) , 2018, DOI: 10.4236/jhepgc.2018.42019
Abstract: Unifying quantum and classical physics has proved difficult as their postulates are conflicting. Using the notion of counts of the fundamental measures—length, mass, and time—a unifying description is resolved. A theoretical framework is presented in a set of postulates by which a conversion between expressions from quantum and classical physics can be made. Conversions of well-known expressions from different areas of physics (quantum physics, gravitation, optics and cosmology) exemplify the approach and mathematical procedures. The postulated integer counts of fundamental measures change our understanding of length, suggesting that our current understanding of reality is distorted.
Quantum Model of Gravity Unifies Relativistic Effects, Describes Inflation/Expansion Transition, Matches CMB Data  [PDF]
Jody A. Geiger
Journal of High Energy Physics, Gravitation and Cosmology (JHEPGC) , 2018, DOI: 10.4236/jhepgc.2018.44038
Abstract: Presenting a unified model of motion and gravity has proved difficult as current approaches to quantum and classical physics are incompatible. Using measurement quantization—a model that demonstrates the physical significance of Planck’s units of length, mass, and time—measure is expressed as counts of the fundamental units establishing a common framework for describing quantum and cosmological phenomena with expressions that are defined throughout the entire physical domain. Beginning with the Pythagorean Theorem, we demonstrate an understanding of measure with respect to static and moving references. The model is extended to include the measure of mass thus completing a single approach for describing the contraction and dilation of measure. With this new approach, relativistic effects are now described as properties of quantized finite units of measure. In support of the model, several descriptions of phenomena are resolved that match our most precise data such as the measure of dark energy, universal expansion, mass distribution, and the age of the Cosmic Microwave Background.
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