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Search Results: 1 - 10 of 275 matches for " SF;Cogo "
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Low-level laser therapy decreases local effects induced by myotoxins isolated from Bothrops jararacussu snake venom
Barbosa, AM;Villaverde, AB;Guimar?es-Sousa, L;Soares, AM;Zamuner, SF;Cogo, JC;Zamuner, SR;
Journal of Venomous Animals and Toxins including Tropical Diseases , 2010, DOI: 10.1590/S1678-91992010000300014
Abstract: the prominent myotoxic effects induced by bothrops jararacussu crude venom are due, in part, to its polycationic myotoxins, bthtx-i and bthtx-ii. both myotoxins have a phospholipase a2 structure: bthtx-ii is an active enzyme asp-49 pla2, while bthtx-i is a lys-49 pla2 devoid of enzymatic activity. in this study, the effect of low-level laser therapy (lllt), 685 nm laser at a dose of 4.2 j/cm2 on edema formation, leukocyte influx and myonecrosis caused by bthtx-i and bthtx-ii, isolated from bothrops jararacussu snake venom, was analyzed. bthtx-i and bthtx-ii caused a significant edema formation, a prominent leukocyte infiltrate composed predominantly by neutrophils and myonecrosis in envenomed gastrocnemius muscle. lllt significantly reduced the edema formation, neutrophil accumulation and myonecrosis induced by both myotoxins 24 hours after the injection. lllt reduced the myonecrosis caused by bthtx-i and bthtx-ii, respectively, by 60 and 43%; the edema formation, by 41 and 60.7%; and the leukocyte influx, by 57.5 and 51.6%. in conclusion, lllt significantly reduced the effect of these snake toxins on the inflammatory response and myonecrosis. these results suggest that lllt should be considered a potential therapeutic approach for treatment of local effects of bothrops species venom.
The lung at high altitude
Annalisa Cogo
Multidisciplinary Respiratory Medicine , 2011, DOI: 10.1186/2049-6958-6-1-14
Abstract: A new classification of altitude levels based on the effects on performance and well-being has been recently proposed [1]: the decrease in partial pressure of oxygen reduces maximal oxygen uptake and impairs "aerobic" performance by reducing maximal aerobic power. Submaximal exercise performance is also impaired at altitude. When the acclimatization is not adequate, hypoxia triggers maladaptive responses that lead to various forms of high altitude illness or acute mountain sickness (AMS), characterized by headache plus gastrointestinal symptoms (anorexia, nausea) and sleep disturbances. AMS is present in 10-30% of subjects at altitudes between 2500 and 3000 m a.s.l. and is usually due to a fast ascent. It is well defined by the short phrase: "Too fast, too high". Less frequent, but much more serious, consequences are high-altitude cerebral edema (HACE), and high-altitude pulmonary edema (HAPE).The lung response to acute altitude exposure is mainly hyperventilation which, together with elevated heart rate, aims at achieving an adequate supply of oxygen to the tissues. At rest, ventilation increases by firstly increasing the tidal volume, at least up to 3500 m. Above this altitude, also the breathing rate significantly increases. Besides the compensatory response, other mechanisms affect lung physiology during hypoxic exposure: the increase of pulmonary artery pressure and endothelial permeability which can explain the extravascular lung fluid accumulation described in many papers [2]. It must be underlined that the interstitial fluid accumulation which affects a large part of climbers at high altitude should be considered a para-physiological mechanism and does not predict subsequent pulmonary edema [3].The role of the lung in the acute exposure to altitude was first described by Angelo Mosso, physiologist at the University of Torino, at the end of the 19th century. He very well pointed out the changes in ventilation and the reduction of lung volumes consistent with
Libraries Demonstrate Low Adherence to Virtual Reference Service Guidelines. A Review of: Shachaf, Pnina, and Sarah M. Horowitz. “Virtual Reference Service Evaluation: Adherence to RUSA Behavioral Guidelines and IFLA Digital Reference Guidelines.” Library & Information Science Research 30.2 (2008): 122-37.
Elise Cogo
Evidence Based Library and Information Practice , 2009,
Abstract: Objectives – This study evaluates the level to which virtual (asynchronous e-mail) reference services adhere to professional guidelines. Specifically, it addresses the following research questions: 1) To what extent do virtual reference services adhere to the American Library Association (ALA) Reference and User Services Association (RUSA) and the International Federation of Library Associations (IFLA) guidelines? 2) How does the level of adherence to RUSA or IFLA guidelines vary based on request type, user name, and institution? 3) Is there a correlation between outcome measures of reference transactions (accuracy, completeness, and satisfaction) and the level of adherence to RUSA or IFLA guidelines? Design – Unobtrusive evaluation of researcher-generated queries. Setting – Fifty-four academic libraries in North America. Subjects – A total of 324 queries were sent to the 54 libraries, with each library receiving six different types of requests from six different user names. Methods – Researchers developed two coding schemes for the guidelines (34 codes and 12 attributes for the RUSA guidelines and 33 codes and 10 attributes for the IFLA guidelines). Each of the six user names used represented an ethnic and/or religious group identity: Mary Anderson (Caucasian, Christian), Moshe Cohen (Caucasian, Jewish), Ahmed Ibrahim (Arab), Latoya Johnson (African American), Rosa Manuz (Hispanic), and Chang Su (Asian). The six request types were designed so that three would be answered (questions 1-3) and three would be out of scope and not answered (questions 4-6). The following queries were sent, individualized for each institution: 1) Dissertation query; 2) Sports team query; 3) Population query; 4) Subject query; 5) Article query; 6) Request for a PDF copy. The 324 queries were uploaded into NVivo 2 software, and all e-mail transactions were coded and analyzed. Main Results – Analysis of the 324 transactions from 54 libraries showed the following results:1) Low levels of adherence to both sets of guidelines;2) Varied levels of adherence based on request types and user names on both sets of guidelines;3) Variation in institutional rank according to different sets of guidelines;4) No correlation between user satisfaction and adherence to either set of guidelines. Conclusion – This study suggests that higher levels of virtual reference service effectiveness could be achieved by automatically integrating some less observed behaviours (e.g., thank you notes) into replies sent to users and by increasing librarians’ awareness of professional guidelines through training
O Outro migrante: das estratégias de midiatiza o das migra es contemporaneas na mídia impressa brasileira
Denise Cogo
Ciberlegenda , 2011,
Abstract: O artigo analisa os processos de produ o de sentido sobre os fen menos migratórios contemporaneos na mídia impressa brasileira. A partir das inter-rela es entre processos de midiatiza o, experiência migratória e interculturalidade, é desenvolvido um mapeamento inicial e uma análise discursiva sobre as estratégias de midiatiza o das migra es e das falas imigrantes em uma amostra de jornais representativos das cinco regi es brasileiras e uma das principais revistas de circula o nacional.
Information seeking Behavior of lecturers in Faculties of Education in Obafemi Awolowo University, Ile Ife and University of Ibadan
SF Akinola
Samaru Journal of Information Studies , 2009,
Abstract: The study investigate the information seeking patterns and types of information sources used on the internet by lecturers in Faculties of Education in Obafemi Awolowo University, Ile Ife and University of Ibadan. The study employed the descriptive research method, using questionnaire for data collection. One hundred lecturers constituted the sample, comprising 54 from University of Ibadan and 46 from Obafemi Awolowo University. The study concluded that majority of the respondents from both universities seek information to update knowledge; 5.4 percent from U.I while 36 percent responded from O.A.U. The study recommended that the two University libraries should increase their internet bandwidth to improve their Internet speeds.
Medical negligence
SF Otto
South African Journal of Radiology , 2004,
Abstract: The progress made in diagnostic and therapeutic medicine has resulted in an increase in the number of malpractice suits brought against medical practitioners. To constitute negligence it must be shown that the conduct of the accused did not measure up to the standard of care the law required of him in the particular circumstances and that he acted with guilt and therefore can be blamed for the deed. This paper describes medical practitioner negligence and reviews relevant cases.
Identification of a biomarker of sleep deficiency-are we tilting windmills?
Quan SF
Southwest Journal of Pulmonary and Critical Care , 2012,
Abstract: No abstract available. Article truncated at 150 words. The amount of time spent asleep by adults in the United States and other developing countries is decreasing. It is estimated that over 40 years ago, adults slept in excess of 8 hours per night, but now sleep barely 7 hours per night (1) During this time frame, there has been a corresponding increase in obesity and diabetes mellitus which in part has been attributed to a reduction in time sleeping (2). In addition, sleep deficiency and other sleep disorders have been implicated as risk factors for hypertension, cardiovascular disease and cancer (3-5). Consequently, billions of excess health care dollars are spent on medical conditions associated with sleep deficiency or sleep disorders (6,7). Their impact also include substantial costs resulting from lost productivity as well as increased absenteeism, presenteeism and motor vehicle or industrial accidents (6,7). Thus, sleep disorders and sleep deficiency are significant threats to public health and productivity…
Obstructive sleep apnea and cardiovascular disease: back and forward in time over the last 25 years
Quan SF
Southwest Journal of Pulmonary and Critical Care , 2012,
Abstract: Over the past 25 years, there have been significant advances made in understanding the pathophysiology and cardiovascular consequences of obstructive sleep apnea (OSA). Substantial evidence now implicates OSA as an independent risk factor for the development of hypertension, coronary artery disease, congestive heart failure and stroke, as well as increased risk of death. Pathophysiologic mechanisms include release of inflammatory mediators, oxidative stress, metabolic dysfunction, hypercoagulability and endothelial dysfunction. Although non-randomized intervention studies suggest that treatment of OSA with continuous positive airway pressure may mitigate its impact of the development of cardiovascular disease, randomized clinical trials are lacking.
Hyperglycemia induced by subchronic co-administration of chlorpyrifos and lead in Wistar rats: Role of pancreatic lipoperoxidation and alleviating effect of vitamin C
SF Ambali
Biology and Medicine , 2011,
Abstract: Studies were conducted to evaluate the role of pancreatic lipoperoxidation on hyperglycemia induced by subchronicco-administration of chlorpyrifos (CPF) and lead (Pb) in Wistar rats and the ameliorative effect of vitamin C. Fortymale Wistar rats divided into 4 groups of 5 animals in each group were used for this study. Rats in group were dosedwith corn oil (2 ml/kg) while those in group II were dosed with vitamin C (100 mg/kg). Group III were co-administeredCPF ( 4.25 mg/kg~ 1/20th LD50) and Pb (250 mg/kg~1/20th LD50) while those in group IV were pretreated with vitaminC (100 mg/kg) and then co-administered with CPF (4.25 mg/kg) and Pb (250 mg/kg) 30 min later. The regimen wereadministered once daily by gavage for a period of 9 weeks. The rats were sacrificed and serum obtained from theblood samples were analyzed for glucose concentration. The liver and pancreas samples were analyzed for glycogenand malonaldehyde (MDA) concentrations, respectively. The study showed that co-administration of CPF and leadcaused increased glucose and MDA concentrations, and a reduced glycogen concentration. Pretreatment withvitamin C restored the concentrations of glucose, glycogen and MDA to apparently normal level. In conclusion,pretreatment with vitamin C restored the hyperglycemia and reduced glycogen concentration induced by coadministrationof CPF and Pb partly due to its antioxidant properties.
SF Tong
Malaysian Family Physician , 2007,
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