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Search Results: 1 - 10 of 325613 matches for " S.;Noa "
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Customer Satisfaction, Switching Costs and Customer Loyalty: An Empirical Study on the Mobile Telecommunication Service  [PDF]
Noa Willys
American Journal of Industrial and Business Management (AJIBM) , 2018, DOI: 10.4236/ajibm.2018.84070
Abstract: Previous research mentioned that Customer satisfaction and switching cost play an important role on customer loyalty. Based on empirical study, this present research attempts to evaluate the effect of the switching cost on customer loyalty and identify which one among switching cost dimensions and Customer satisfaction has the most influence on customer loyalty; then investigate the moderate effect of switching cost between customer satisfaction and customer loyalty link. To test the theoretical model, 300 questionnaires were self-administered to the subscribers of all mobile telecommunication providers in Madagascar and 273 questionnaires were returned with 253 questionnaires claimed efficient. Then SPSS 20.0 and regression method was used to establish the relationship between the dependent and independent variables. The findings indicate that there is significant relationship between switching cost and customer loyalty, then customer satisfaction and customer loyalty. It is also showed that among the dimensions of switching cost, financial cost has the most influence on customer loyalty. Even though switching cost shows up a strong effect to customer loyalty, it is always proved that satisfaction is the
Non-Convexity
Noa Nitzan
Mathematics , 2009,
Abstract: Suppose S is a planar set. Two points a,b in S 'see each other' via S if [a,b] is included in S . F. Valentine proved in 1957 that if S is closed, and if for every three points of S, at least two see each other via S, then S is a union of three convex sets. The pentagonal star shows that the number three is best possible. We discard the condition that S is closed and show that S is a union of (at most) six convex sets. The number six is best possible.
A Ganzstellensatz for semi-algebraic sets and a boundedness criterion for rational functions
Noa Lavi
Mathematics , 2011,
Abstract: Let $\langle K,\nu \rangle$ be a real closed valued field, and let $S\subseteq K^n$ be an open semi-algebraic set. Using tools from model theory, we find an algebraic characterization of rational functions which admit, on $S$, only values in the valuation ring. We use this result to deduce a criterion for a rational function to be bounded on an open semi algebraic subset of some irreducible variety over a real closed field or over an ordered field which is dense in its real closure.
Positivstellens?tze for semi-algebraic sets in real closed valued fields
Noa Lavi
Mathematics , 2011,
Abstract: The purpose of this paper is to give a characterization for polynomials and rational functions which admit only non-negative values on definable sets in real closed valued fields. That is, generalizing the relative positivstellens\"atze for sets defined also by valuation terms. For this, we use model theoretic tools, together with existence of canonical valuations.
NIVELES DE AFLATOXINA M1 EN LECHE CRUDA Y PASTEURIZADA COMERCIALIZADA EN LA ZONA METROPOLITANA DE GUADALAJARA, MéXICO
Patricia,Landeros; Noa,M; López,Yolanda; González,Delia G; Noa,Elizabeth; Real,M; Juárez,C; Medina,Miriam S;
Revista de Salud Animal , 2012,
Abstract: aflatoxin m1 (afm1) is a milk hygiene quality indicator established in mexico. aflatoxin m1 is a metabolite of aflatoxin b1 (afb1), becoming from contaminated feed. the thermal treatments usually applied to raw milk did not reduce the concentrations on afm1 in milk. the aim of the present work was to conduct a screening of afm1 i raw (n=50) collected from raw milk collecting facilities and 7 pasteurized milk brand (n=84) samples. all the samples tested were both produced in jalisco state and commercialized in guadalajara, mexico. the analyses were performed using the competitive direct elisa kit agraquant? aflatoxin m1 (romer labs). statistical analysis was performed using a one-way anova by sigma stat 3.0 program. afm1 was found in 100% of the tested samples, ranging from < 0.005 to 0.100 μg/l in raw milk, and from < 0.005 to 0.637 μg in pasteurized milk. a total 18.6% (25/134) samples showed levels above maximum residue limit (mrl) established by the european community (0.05 μg/kg), 0.7% (1/134) for raw and 17.9% (24/134) for pasteurized milk. only 0.7% (1/134) of the tested samples exceeded this mrl established in mexico by nom-243-ssa1-2010 which is 0.5 μg/l afm1. statistical differences were found (p<0.05) between sampling months; the highest level was detected in december, while no differences were detected among milk collecting facilities and either among pasteurized milk brands.
Mutations in the SLC2A9 Gene Cause Hyperuricosuria and Hyperuricemia in the Dog
Danika Bannasch ,Noa Safra,Amy Young,Nili Karmi,R. S. Schaible,G. V. Ling
PLOS Genetics , 2008, DOI: 10.1371/journal.pgen.1000246
Abstract: Allantoin is the end product of purine catabolism in all mammals except humans, great apes, and one breed of dog, the Dalmatian. Humans and Dalmatian dogs produce uric acid during purine degradation, which leads to elevated levels of uric acid in blood and urine and can result in significant diseases in both species. The defect in Dalmatians results from inefficient transport of uric acid in both the liver and renal proximal tubules. Hyperuricosuria and hyperuricemia (huu) is a simple autosomal recessive trait for which all Dalmatian dogs are homozygous. Therefore, in order to map the locus, an interbreed backcross was used. Linkage mapping localized the huu trait to CFA03, which excluded the obvious urate transporter 1 gene, SLC22A12. Positional cloning placed the locus in a minimal interval of 2.5 Mb with a LOD score of 17.45. A critical interval of 333 kb containing only four genes was homozygous in all Dalmatians. Sequence and expression analyses of the SLC2A9 gene indicated three possible mutations, a missense mutation (G616T;C188F) and two promoter mutations that together appear to reduce the expression levels of one of the isoforms. The missense mutation is associated with hyperuricosuria in the Dalmatian, while the promoter SNPs occur in other unaffected breeds of dog. Verification of the causative nature of these changes was obtained when hyperuricosuric dogs from several other breeds were found to possess the same combination of mutations as found in the Dalmatian. The Dalmatian dog model of hyperuricosuria and hyperuricemia underscores the importance of SLC2A9 for uric acid transport in mammals.
SERpredict: Detection of tissue- or tumor-specific isoforms generated through exonization of transposable elements
Britta Mersch, Noa Sela, Gil Ast, Sándor Suhai, Agnes Hotz-Wagenblatt
BMC Genetics , 2007, DOI: 10.1186/1471-2156-8-78
Abstract: As we aimed at detecting other tissue- or tumor-specific isoforms in human and mouse genomes which were generated through exonization of a transposed element, we designed the automated analysis pipeline SERpredict (SER = Specific Exonized Retroelement) making use of Bayesian Statistics. With this pipeline, we found several genes in which a transposed element formed a tissue- or tumor-specific isoform.Our results show that SERpredict produces relevant results, demonstrating the importance of transposed elements in shaping both the human and the mouse transcriptomes. The effect of transposed elements on the human transcriptome is several times higher than the effect on the mouse transcriptome, due to the contribution of the primate-specific Alu elements.Transposed elements (TEs) are sequences of DNA that can move from one position to another in the genome. There are two classes of transposed elements, the DNA transposons and the retroelements. DNA transposons usually move by cut and paste using the transposase enzyme. In contrast, retroelements are genetic elements that integrate in a genome via an RNA intermediate which is reverse-transcribed to DNA. In mammals, almost half the genome is comprised of TEs: around 45% of the human genome is made up of them. This translates to millions of elements, so that on average, every gene in our genome contains about 3 transposed elements. Transposed elements comprise approximately 37% of the mouse genome.The human and mouse genome sequences show that TEs have played an important role in shaping the genomes [1,2]. The human genome contains retroelements such as Alu, which is a short interspersed element (SINE), MIR (mammalian interspersed repeat) as well as LINE-1 (L1), LINE-2 (L2) and CR1 (L3). The last three of the given families of retroelements are termed long interspersed elements. In addition, the human genome contains LTR elements such as MaLR (mammalian apparent LTR-retrotransposon), ERVL and ERV1 (endogenous retroviruses
Participación de las mujeres en los ensayos clínicos según los informes de la Agencia Espa?ola de Medicamentos y Productos Sanitarios: 2007
Laguna Goya,Noa; Andrés Rodríguez-Trelles,Fernando de;
Revista Espa?ola de Salud Pública , 2008, DOI: 10.1590/S1135-57272008000300010
Abstract: background: the evaluation of the gender bias in clinical trials is not unanimous. the aim of this study has been the assessment of the current situation in spain regarding the manipulation of data from clinical trials at the publication of the law of equality. methods: we have examined the study design, sample population, demographic data and baseline clinical characteristics of participants, results and conclusions of the trial in the summaries of the final reports of clinical trials received in the first four months of 2007 in the agencia espa?ola de medicamentos y productos sanitarios. results: from twenty-five documents analysed, in their results and conclusions: five subdivide data sets by age and gender, thirteen do not subdivide data by gender nor do they provide a conclusion, three do not subdivide results neither but do describe severe side effect by gender and four others provide no results or conclusions. conclusions: only twenty percent of the reviewed summaries provide data subdivided by gender. this could be due to the fact that it has not been made or that it was not given enough importance to include it in the summary, neither of which is satisfactory. a more detailed study is difficult due to the current quality of the summaries provided of the final reports of the clinical trials, which is the only document that is mandatory to send to the aemps once the trial has concluded. we expect that with the publication of the new law of equality this situation will improve, given the growing evidence of the relevance of the subdivision by gender.
Fisiopatología, tratamiento y modelos experimentales de artritis reumatoide
Noa Puig,Miriam; Más Ferreiro,Rosa; Mendoza Casta?o,Sarahí; Valle Clara,Maikel;
Revista Cubana de Farmacia , 2011,
Abstract: the rheumatoid arthritis, is the inflammatory polyarthritis commonest in adults affecting about the 1 % of world population, more predominant in women than men and more frequent in those aged 30 and 50 and entails a high level of inability of patient. it is characterized by a symmetrical erosive synovitis with proliferation of conjunctival tissue (pannus), invading and eroding the cartilage and joint bones, and sometimes, by a multisystem affection. in most patients the disease follows a fluctuating chronic course, which it is not treated, provoke a progressive destruction, deformity and inability of involved joints. the disease evolves with high figures of rheumatoid factor and/or anti- citrulline antibodies. these are essential features of an optimal treatment of this entity include: early differential diagnosis, initial treatment with non-steroidal anti-inflammatory drugs (nsaids), the use of disease course modifying drugs, the potential use of oral low-dose glucocorticoid agents or intra-articular injections, and a periodical assessment of treatment fitting (radiological serum and functional monitoring of disease progression and of treatment-associated toxicity) and the educational and rehabilitations interventions of patient. to assess the new therapies for treatment of rheumatoid arthritis, the more uses models are: that of the arthritis induced by adjuvant drugs in rats and the arthritis induced by collagen in rats and mice. other new models show limited data. effectiveness of several compounds reveals that its therapeutic effect is more predictive of the clinical effect in the human being when models of arthritis due to adjuvant drugs and collagen than data from an only one model.
EL CONSENTIMIENTO INFORMADO EN PACIENTES PEDIATRICOS CON INDICACION DE OTOCIRUGIA POR COLESTEATOMA
Quintero Noa,Julianis Loraine; Más García,Martha de las Nieves; Morera Barrios,Luz Mireya;
Revista Habanera de Ciencias M??dicas , 2007,
Abstract: the next of kin consent has lately been used in the medical practice, because the principles of doctor-patient relationship have been modified. a bibliographic revision was conducted about the next of kin consent. elements concerning requisites, functions, content and information limits were analyzed by pointing out the importance of ethical and bioethical issues. author's criteria are stated in reference to diagnostic and surgical decisions in pediatric patients scheduled for ear surgery due to colesteatoma. it was concluded the importance of accurate, kind, accessible information in paediatric ear surgery regarding the educational level of each family, particularly the most responsible and competent next of kin without alarming the child guaranteeing his or her respect of autonomy and contributing to the success of the surgical treatment .
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