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Search Results: 1 - 10 of 325017 matches for " S. Rajasekaran "
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A Parameter Estimation Model of G-CSF: Mathematical Model of Cyclical Neutropenia  [PDF]
S. Balamuralitharan, S. Rajasekaran
American Journal of Computational Mathematics (AJCM) , 2012, DOI: 10.4236/ajcm.2012.21002
Abstract: We investigate the FFT (Fast Fourier Transform) model and G-CSF (granulocyte colony-stimulating factor) treatment of CN (Cyclical Neutropenia). We collect grey collies and normal dog’s data from CN and analyze the G-CSF treatment. The model develops the dynamics of circulating blood cells before and after the G-CSF treatment. This is quite natural and useful for the collection of laboratory data for investigation. The proposed interventions are practical. This reduces the quantity of G-CSF required for potential maintenance. This model gives us good result in treatment. The changes would be practical and reduce the risk side as well as the cost of treatment in G-CSF.
Obituary- Prof T K Shanmugasundaram (1929 - 2008)
Rajasekaran S
Indian Journal of Orthopaedics , 2008,
Ganga hospital open injury severity score - A score to prognosticate limb salvage and outcome measures in Type IIIb open tibial fractures
Rajasekaran S
Indian Journal of Orthopaedics , 2005,
Abstract: Background: Gustilo′s grade IIIB classification includes a wide spectrum of injuries and is limited by high inter and intra observer error rates. Methods: A trauma score for grade IIIB open tibial fractures was devised to assess injury to three components; the covering tissues, musculotendinous units and bone with the severity scale in each category from one to five. Seven co-morbid conditions known to influence the prognosis were each given a score of two and summed up. Results : Ninety six consecutive Grade IIIB open injuries of tibia were prospectively evaluated. At 3-5 year follow up, of the 88 available, final score was less than five in 6 patients (Group I), between six and ten in 48 (Group II), eleven to fifteen in 29 (Group III) and above 16 in five (Group IV). All patients in Group IV and one in Group III with score of fifteen underwent amputation. There was a significant difference (p less than 0.001) between the three groups in the requirement for flap (16.7,75&100 percent), time for union (16.3,24.9 &46.9), incidence of deep infection (0,22.9 &60.7 percent), number of surgical procedures (1.2,3.1 &6.3) and inpatient days (12.5,22.6 &59.4). A score of greater than three in any one component required special skills in management and interfered with healing of other structures. Conclusion: The scoring system was easy to apply and had a high degree of interobservor aggreement rate. This comprehensive score reliably prognosticates both limb salvage and outcome measures in severe open injuries of tibia.
Fuzzy Based Intelligent Monitoring of Critical Lines in the Restructured Power Market  [PDF]
S. Rajasekaran, S. Sathiyamoorthy
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79191
Abstract: Restructured electric market environment allows the power wheeling transactions between the power producers and customers to meet the growing load demand. This will lead to the possible of congestion in the transmission lines. The possible contingencies of power components further worsen the scenario. This paper describes the methodology for the identification of critical transmission line by computing the real power and reactive power performance indices. It also demonstrates the importance of fuzzy logic technique used to rank the transmission lines according to the severity and demonstrated on IEEE-30 bus system.
Coefficient Estimates for α-λ Sprial-Like Functions of Order β
S. Rajasekaran,K. Subathra
Journal of Modern Mathematics and Statistics , 2012,
Abstract: Let α≥ 0, 0 ≤β< 1, |λ| < π/2 and suppose that f(z) = z + is said to be α- λsprial-like of order β if it satisfies Re {(eiλ- α) zf (z)/f(z) + α(1+zf (z)/f (z)). In this study we determine sharp bounds for the moduli |an| of the coefficients.
Firefly Algorithm in Determining Maximum Load Utilization Point and Its Enhancement through Optimal Placement of FACTS Device  [PDF]
S. Rajasekaran, Dr. S. Muralidharan
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.710262
Abstract: In a Power System, load is the most uncertain and extremely time varying unit. Hence it is important to determine the system’s supreme acceptable loadability limit called maximum loadabilitypoint to accommodate the sudden variation of load demand. Nowadays the enhancement of themaximum loadability point is essential to meet the rapid growth of load demand by improvising the system’s load utilization capacity. Flexible AC Transmission system devices (FACTS) with their speed and flexibility will play a key role in enhancing the controllability and power transfer capability of the system. Considering the theme of FACTS devices in the loadability limit enhancement,in this paper maximum loadability limit determination and itsenhancement are prepared with the help of swarm intelligence based meta-heuristic Firefly Algorithm(FFA) by finding the optimal loading factor for each load and optimally placing the SVC (Shunt Compensation) and TCSC (SeriesCompensation) FACTS devices in the system. To illuminate the effectiveness of FACTS devices inthe loadability enhancement, the line contingency scenario is also concernedin the study. The study of FACTS based maximum system load utilization acceptability point determination is demonstrated with the help of modified IEEE 30 bus, IEEE 57 Bus and IEEE 118 Bus test systems. The results of FACTS devices involvement in determining the maximum loading point enhance the load
Immune Reconstitution Tuberculosis in HIV Patients after Antiretroviral Therapy
Rajasekaran S, Vijila, Ravichandran N
JK Science : Journal of Medical Education & Research , 2006,
Abstract: Free antiretroviral therapy is being given to eligible people living with HIV in India since April 2004.Govt. Hospital of Thoracic Medicine, Tambaram Sanatorium, Chennai is one of the largest centers managingHIV/AIDS patients with antiretroviral therapy in India.This study finds out the incidence of tuberculosisas the manifestation of ‘Immune Reconstitution Syndrome (IRS)’ after the initiation of Antiretroviraltherapy in patients with HIV/AIDS. All the patients, placed under ART, were followed up for the occurrenceof tuberculosis from April 2004 to December 2005 at GHTM, Tambaram Sanatorium, Chennai. 2330HIV patients were initiated antiretroviral therapy till December 2005 and of whom 1409 (61%) werealready treated for tuberculosis. 302 (12.9%) had IRS and 81 (3.5%) had tuberculosis, as the componentof IRS. Occurrence of tuberculosis as IRS manifestation is significantly high after antiretroviral therapy.This results in starting or restarting anti tuberculosis treatment with the changed or modified antiretroviraltherapy in a large number of patients, escalating treatment cost.
Response of Arbuscular mycorrhizal fungi and Rhizobium inoculation on growth and chlorophyll content of Vigna unguiculata (L) Walp Var. Pusa 151
R Arumugam, S Rajasekaran, SM Nagarajan
Journal of Applied Sciences and Environmental Management , 2010,
Abstract: The aim of the present study was to investigate the effect ofRhizobium and Arbuscular mycorrhizal fungi inoculation, both individually and in combination on growth and chlorophyll content of economically important plant Vigna unguiculata L. A significant (p < 0.05) increase over control in root length (45.6 cm), shoot height (12.2 cm), dry weight of root (0.4 g) and shoot (1.8 g), total number of nodules (39.6 nos.), dry weight of nodules (0.5 g), percentage of mycorrhizal infection (96.6 %), chlorophylls a (0.83 mg/g fr.wt.), b (1.19 mg/g fr.wt) and total chlorophyll (2.24 mg/g fr.wt) was recorded in dual inoculated (AM fungi and Rhizobium) plants than plants with individual inoculation. Thus it is clear that the dual inoculation with AM Rhizobium biofertilizer is more effective than the individual treatment. @JASEM J. Appl. Sci. Environ. Manage. December, 2010, Vol. 14 (4) 113 - 115
Hepatoprotective Effect of Adenema hyssopifolium G. Don (Gentianaceae) in Carbon Tetrachloride-Induced Hepatotoxicity in Rats
A Rajasekaran, R Arivukkarasu, S Murugesh
Tropical Journal of Pharmaceutical Research , 2010,
Abstract: Purpose: The effects of oral administration of ethyl acetate, ethanol and aqueous extracts of Adenema hyssopifolium G.Don (Gentianaceae) on carbon tetrachloride-induced liver disorders were investigated. Methods: Rats were individually treated daily with 300 and 600 mg/kg dose of either ethyl acetate, ethanol or aqueous extracts of A. hyssopifolium, respectively, following induction of liver damage with the hepatotoxin, carbon tetrachloride. The hepatoprotective activity of the extracts was assessed by estimating the levels of serum aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), alkaline phosphatase (ALP) and total bilirubin (TBL) in the rats. Silymarin was used as the reference hepatoprotective agent. Acute toxicity test on the extracts in male mice was also carried out. Results: At doses of 300 and 600 mg/kg p.o., the ethyl acetate and ethanol extracts showed significant (p < 0.001 and p < 0.01) dose-dependent hepatoprotective activity, showing decreases in serum levels of ASAT, ALAT, ALP and TBL. The aqueous extract, however, did not exert any significant effect on hepatoprotective activity. All three extracts, up to a dose of 3000 mg/kg p.o. each, did not cause mortality in the acute toxicity test. Conclusion: The ethyl acetate and ethanol extracts showed significant hepatoprotective activity when compared to untreated (normal) control group while the aqueous extract did not. The active extracts could find future use in countering hepatic damage.
Direct repair of lumbar spondylolysis by Buck′s technique
Rajasekaran S,Subbiah M,Shetty Ajoy
Indian Journal of Orthopaedics , 2011,
Abstract: Background: The lesion in spondylolysis is a nonunion that follows a fatigue fracture of pars interarticularis. Direct repair of the pars defect is a logical alternative to fusion as it helps to preserve the motion segment and prevents abnormal stresses at the adjacent levels. The purpose of the study is to analyze the clinical and radiological results of direct screw osteosynthesis of the pars defect by the Buck′s method in patients with symptomatic spondylolysis with or without grade 1 spondylolisthesis. Materials and Methods: Nine patients (six males, three females, mean age 24 years) with symptomatic spondylolysis with or without grade 1 spondylolisthesis and a normal disc in magnetic resonance imaging (MRI), who failed conservative treatment, underwent surgery between January 2000 and April 2009. Of them five patients had bilateral lysis at one level, one had bilateral lysis at three levels and two levels each and two had unilateral lysis at one level. Direct pars repair by the Buck′s method with internal fixation of the defect using 4.5 mm cortical screws and cancellous bone grafting was done. The mean follow-up period was 45 months. MacNab criteria were used to evaluate the postoperative functional outcome. Healing of the pars defect was assessed by plain radiographs and computed tomography (CT) scan. Results: Spondylolysis was bilateral in seven and unilateral in two patients. Two patients had associated grade 1 spondylolisthesis. The mean operative time was 58 minutes (range 45 - 75 minutes) and blood loss was 98 ml (50 - 140 ml). Although radiological fusion was observed in all patients at a mean follow-up of 45 months (range 9 to 108 months), the functional outcome was excellent in two patients and good in five, with one fair and one poor result. The overall result of the procedure was satisfactory in 78% (7/9) of the patients. The two patients with associated grade 1 spondylolisthesis had fair and poor results. No complications were encountered in the perioperative or postoperative period. Conclusions: In carefully selected patients, direct repair of the pars defect by the Buck′s technique of internal fixation and bone grafting was a safe and effective alternative to fusion in younger patients with symptomatic spondylolysis, without associated spondylolisthesis, who failed conservative management.
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