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Search Results: 1 - 10 of 346446 matches for " Sérgio Ribeiro do;Lira "
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Comportamento de linhagens de sorgo forrageiro submetidas a déficit hídrico sob condi o controlada
Amaral Sérgio Ribeiro do,Lira Mário de Andrade,Tabosa José Nildo,Santos Mércia Virginia Ferreira dos
Pesquisa Agropecuária Brasileira , 2003,
Abstract: O objetivo deste trabalho foi avaliar os efeitos do estresse hídrico no estabelecimento, desenvolvimento e na taxa de sobrevivência de 11 linhagens de sorgo forrageiro em casa de vegeta o. O delineamento experimental foi o de blocos ao acaso no arranjo de parcelas subdivididas no tempo, com cinco repeti es. As unidades experimentais foram constituídas por recipientes de 250 L, onde foram colocados 187,9 kg de solo da classe textural areia franca. O estudo compreendeu dois períodos de estresse, e três irriga es, sendo uma no início e as outras aplicadas quando grande número de folhas tinham aspecto de palha seca. No primeiro período, as linhagens apresentaram alta taxa de sobrevivência, demonstrando resistência ao estresse hídrico. As linhagens que apresentaram menor velocidade de crescimento nesse período sofreram menos com o estresse. No segundo período n o ocorreram diferen as significativas entre as linhagens com rela o ao desenvolvimento das plantas. Durante os dois períodos de estresse, a velocidade de crescimento n o diferenciou satisfatoriamente linhagens de comportamento distintos, quanto à resistência à seca, competindo em um mesmo recipiente e em alta densidade populacional. As linhagens 84, 29, 99, 41, 63 e 104 apresentaram maior resistência ao estresse hídrico e as linhagens 33, 38, 40, 67 e 92, menor resistência.
Comportamento de linhagens de sorgo forrageiro submetidas a déficit hídrico sob condi??o controlada
Amaral, Sérgio Ribeiro do;Lira, Mário de Andrade;Tabosa, José Nildo;Santos, Mércia Virginia Ferreira dos;Mello, Alexandre Carneiro Le?o de;Santos, Venésio Felipe dos;
Pesquisa Agropecuária Brasileira , 2003, DOI: 10.1590/S0100-204X2003000800010
Abstract: the objective of this work was to evaluate the effects of water deficit stress on establishment, development and survival rate of 11 forage sorghum lines in a greenhouse. the experiment was carried out under a randomized block design, with split-splot arrangement and five replications. each replication was formed by a container of 250 l capacity, filled with 187.9 kg of sandy soil. two stress periods were studied, with three irrigations, at the begining of tests and when the plants showed large numbers of dry leaves. during the first period all lines had high survival rates showing resistance to water deficit stress. slower growing lines suffered less with the imposed water deficit. during the second water deficit stress period there were no significant differences between the lines in plant development. along both stress periods, growth rate did not distinguish satisfactorily lines with distinct behavior, as relate to drought resistance, when those lines were competing on the same recipient and high population density. lines 84, 29, 99, 41, 63, and 104 had higher stress resistant while lines 33, 38, 40, 67, and 92 had lower stress resistant.
Gum Guar fiber associated with fructose reduces serum triacylglycerol but did not improve the glucose tolerance in rats
Caio SM Motoyama, M?nica JS Pinto, Fabio S Lira, Eliane B Ribeiro, Claudia MO do Nascimento, Lila M Oyama
Diabetology & Metabolic Syndrome , 2010, DOI: 10.1186/1758-5996-2-61
Abstract: The aim of the present study were to investigate the effects of the supplemental feeding partially hydrolyzed gum guar on glucose and lipid homeostasis, in rats fed with fructose solution.The study was performed on thirty day-old male Wistar rats randomly assigned into four groups: control(C) or treated with fructose (F-20%), fiber (FB-5%), or fructose plus fiber (F-20% + FB-5% = FF) solution for 30 days on glucose tolerance (OGTT), triacylglycerol concentration in the liver by chloroform/methanol method, glucose, triacylglycerol and total cholesterol serum concentration by assayed by enzymatic colorimetric method, insulin receptor (IR) concentration in the liver by Western Blotting.The total body weight gain was not different between groups; in regards of total caloric intake, in the F group was significantly higher and in the FB group was lower than other groups. The triacylglycerol concentration in the liver of FF group was significantly higher than F group, the triacylglycerol concentration in the serum was higher the F group compared with other groups. The OGTT reveal impaired on glucose tolerance in the F, FB, FF compared with C. The IR concentration in the liver was lower in the F, FB, FF compared with C, no significant difference was observed between groups for IR concentration in the gastrocnemius muscle. No significant difference was observed between groups for carcass fat content and serum total cholesterol.Fructose induced important alterations on glucose tolerance and lipid metabolism, despite of fiber showed reversion of part this alterations. The association fructose plus fiber to seem decrease insulin receptor concentration in the liver, with consequent impair on glucose tolerance.Insulin resistance is a key feature of impaired glucose tolerance in type 2-diabetes that can be characterized by a diminished ability of insulin sensitive tissues and a marked decrease of glucose metabolism in response to insulin. The dyslipidemia associated with insulin-r
Comparison of Three Experimental Models for Rat Osteoarthritis Induction  [PDF]
Henrique Ribeiro Rodrigues-Neto, Edilson Ferreira Andrade-Junior, Denilson Jose Silva Feitosa-Junior, André Lopes Valente, Thiago Cesar Xavier, Bianca Caroline do Nascimento Alho, Renan Kleber Costa Teixeira, Fabio Vidal Moriya, Rui Sérgio Monteiro de Barros
Journal of Biosciences and Medicines (JBM) , 2016, DOI: 10.4236/jbm.2016.412010
Abstract: Background: Osteoarthritis is a slowly progressive and debilitating disease with high prevalence in adult population. Knee is one of the joints most affected by this disorder. There are several models for animals’ osteoarthritis induction, however it is not identified any paper that compares these techniques. The present study was aimed to define the most appropriate model for rats osteoarthritis induction. Material and Methods: 40 Wistar rats were distributed into 4 groups of 10 animals each: normality group (NG); meniscectomy group (MG); quinolone group (QG) and iodoacetate group (IG). Radiographic images of the rat’s knees were analyzed as well as the amount of chondrocytes in the epiphyseal and articular cartilage. Results: In the radiographic analysis, there was a low correlation between the raters. Regarding the amount of chondrocytes in the epiphyseal cartilage, it was noticed that the IG and QG groups had fewer chondrocytes than NG, in contrast to MG that reported similar results to normality (p > 0.05). There was no significant difference between IG and QG groups (p > 0.05). Regarding the amount of chondrocytes in articular cartilage, it was noticed that the IG group showed fewer chondrocytes than NG (p < 0.01), in contrast to the QG and MG groups that showed similar results to normality (p > 0.05). There was no significant difference between QG and MG groups (p > 0.05). Conclusion: Intraarticular injection of iodoacetate in rats is the model with greatest effect on reduction of chondrocytes amount.
Supplementing alpha-tocopherol (vitamin E) and vitamin D3 in high fat diet decrease IL-6 production in murine epididymal adipose tissue and 3T3-L1 adipocytes following LPS stimulation
Fábio S Lira, José C Rosa, Claudio A Cunha, Eliane B Ribeiro, Claudia Oller do Nascimento, Lila M Oyama, Jo?o F Mota
Lipids in Health and Disease , 2011, DOI: 10.1186/1476-511x-10-37
Abstract: IL-6 protein levels and the IL-6/IL-10 ratio were decreased in epididymal white adipose tissue in groups receiving vitamins E and D3 supplementation compared to the HFD group. A 24-hour treatment of vitamin D3 and vitamin E significantly reduced the IL-6 levels in the adipocytes culture medium without affecting IL-10 levels.Vitamin D3 and vitamin E supplementation in an HFD had an anti-inflammatory effect by decreasing IL-6 production in epididymal adipose tissue in mice and in 3T3-L1 adipocytes stimulated with LPS. Our results suggest that vitamin E and D3 supplementation can be used as an adjunctive therapy to reduce the proinflammatory cytokines present in obese patients.The incidence of obesity has dramatically increased during the past several decades [1]. In 2006, the World Health Organization estimated that 1.6 billion adults worldwide were overweight and 400 million adults were obese [2]. Although morbidly obese people have a greater food intake than non-obese people, they may suffer from nutritional deficiencies.High fat diets (HFDs) contribute to the accumulation of adipose tissue, resulting in obesity and possibly insulin resistance. Adipose tissue secretes soluble factors called adipokines, which include pro-inflammatory cytokines. It is known that long-term low systemic inflammation that occurs in obese individuals contributes to the development of metabolic syndrome [3]. Lira et al. [4] reported that body fat correlates with cytokine levels, and it was demonstrated that increased body fat was associated with elevated cytokine levels in obese adolescents. Tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), which are increased in obese subjects, may downregulate adiponectin production. In contrast, adiponectin reduces the production and activity of TNF-α and IL-6. IL-6 is considered the major inflammatory mediator in obesity. IL-6 has been implicated in the release of triglycerides and free fatty acids, downregulated lipoprotein lipase, insulin res
Implanta??o de rotinas de rastreamento do uso de risco de álcool e de uma interven??o breve na aten??o primária à saúde: dificuldades a serem superadas
Ronzani, Telmo Mota;Ribeiro, Mário Sérgio;Amaral, Michaela Bitarello do;Formigoni, Maria Lúcia Oliveira de Souza;
Cadernos de Saúde Pública , 2005, DOI: 10.1590/S0102-311X2005000300019
Abstract: the variety of problems related to the so-called hazardous patterns of alcohol use make the latter a prominent public health concern. screening instruments associated with brief interventions in primary care provide one of the frequently recommended secondary prevention strategies. the objective of this study was to assess the implementation of this strategy as a routine practice in primary health care services in the city of juiz de fora, minas gerais state, brazil. a qualitative design was employed, including the application of semi-structured interviews for managers and health care professionals in the city's public health system, in addition to content analysis and participant observation. results point to difficulties in the effective implementation of such routines both by managers and health care professionals. health care professionals limit the approach to alcohol-dependent patients and demonstrate lack of motivation for preventive work. health services managers experience difficulties in the organization and administration of such instruments, despite affirming their interest in the project.
Comportamento de formas sangüícolas do Trypanosoma cruzi obtidas de camundongos utilizados como filtros biológicos, em cultura e em triatomíneo
Ribeiro,Rosa Domingues; Belda Neto,Francisco Miguel; Prado Junior,José Clóvis do; Albuquerque,Sérgio de;
Revista de Saúde Pública , 1986, DOI: 10.1590/S0034-89101986000200003
Abstract: the study of the behaviour of t. cruzi strains in animals as in human beings, runs into great difficulties when the attempt is made to relate the morphology of this parasite to its biological behaviour. the thin forms are able to penetrate vertebrate cells faster than the broad forms. so, faced with the biological complexity of the t. cruzi strains and substrains it was decided to investigate the behaviour of its blood forms obtained from normal mice as biological filters. these mice were endovenously inoculated with blood trypomastigotes from derivated rcl of the t. cruzi rc strain. forty-eight hours later, the animals went through xenodiagnosis and heart punch in order to sow the blood in warren's medium. the trypomastigotes became round (spheromastigotes and/or amastigotes) in the stomach of the triatomines and cultures at 28°c. the behaviour of the broad forms has been frequently observed and leads to the conclusion that the biology of the t. cruzi is not only related to the strain, but, sometimes, to the parasite population.
Epidemiology of vulvar lichen sclerosus and its correlation with other conditions
José Juvenal Linhares,Julieta Massabni Zalc,Renata de Loreto Ribeiro do Val,Eduardo Sérgio Borges da Fonseca
Einstein (S?o Paulo) , 2003,
Abstract: OBJECTIVES: To investigate some epidemiological data of lichensclerosus patients; to verify its association with other conditionsand compare these data with the literature. METHODS:Retrospective analysis of medical records of patients submitted to12,724 vaginal/cervical examinations and vulvoscopies, at Hospitaldo Servidor Público Estadual “Francisco Morato de Oliveira” – S oPaulo, from August 1998 to August 2001. RESULTS: The frequencyof lichen sclerosus confirmed by pathological examination was0.73% among these patients. Mean age was 63.6 years. Mostpatients presenting the condition were aged over 50 years (81/93), and the difference was statistically significant as comparedwith younger subjects (12/93). Caucasian women represented91.4% of the sample and black, 8.6%. Smokers accounted for 8.6%of the cases. Autoimmune diseases were detected in 31.2%,psychiatric disorders in 17.2%, and neoplasms in 11.8% of thosesuffering from lichen sclerosus. The colpocytology of one patientwas classified as Papanicolaou class V. CONCLUSION: These datashow the population studied presented findings similar to thosereported in the literature.
Implanta o de rotinas de rastreamento do uso de risco de álcool e de uma interven o breve na aten o primária à saúde: dificuldades a serem superadas
Ronzani Telmo Mota,Ribeiro Mário Sérgio,Amaral Michaela Bitarello do,Formigoni Maria Lúcia Oliveira de Souza
Cadernos de Saúde Pública , 2005,
Abstract: Tendo em vista os diversos problemas associados ao assim chamado uso de risco de álcool, ele é considerado uma relevante quest o de saúde pública. Uma das estratégias de preven o secundária recomendadas é a utiliza o de instrumentos de rastreamento associados a interven es breves em servi os de aten o primária à saúde. O objetivo deste estudo foi avaliar o processo de implanta o desta estratégia na rotina de aten o primária à saúde da cidade de Juiz de Fora, Minas Gerais, Brasil. Foi utilizada uma abordagem qualitativa, incluindo a aplica o de entrevistas semi-estruturadas a gestores e/ou profissionais da assistência do Sistema Municipal de Saúde, associadas à análise de conteúdo e observa o participante. Os resultados indicam que há dificuldades para a implanta o efetiva destas rotinas, tanto em rela o aos gestores quanto aos profissionais envolvidos diretamente na sua execu o. Quanto aos profissionais destacam-se a restri o da abordagem a dependentes de álcool e a falta de motiva o dos profissionais para trabalhos preventivos. Quanto aos gestores, foram detectadas dificuldades práticas no processo de organiza o e gerenciamento, a despeito de um afirmado interesse no projeto.
Sleep deprivation affects inflammatory marker expression in adipose tissue
José C Rosa Neto, Fábio S Lira, Daniel P Venancio, Cláudio A Cunha, Lila M Oyama, Gustavo D Pimentel, Sérgio Tufik, Cláudia do Nascimento, Ronaldo VT Santos, Marco T de Mello
Lipids in Health and Disease , 2010, DOI: 10.1186/1476-511x-9-125
Abstract: The study consisted of two groups: a control (C) group and a paradoxical sleep deprivation by 96 h (PSD) group. Ten rats were randomly assigned to either the control group (C) or the PSD. Mesenteric (MEAT) and retroperitoneal (RPAT) adipose tissue, liver and serum were collected following completion of the PSD protocol. Levels of interleukin (IL)-6, interleukin (IL)-10 and tumour necrosis factor (TNF)-α were analysed in MEAT and RPAT, and leptin, adiponectin, glucose, corticosterone and lipid profile levels were analysed in serum.IL-6 levels were elevated in RPAT but remained unchanged in MEAT after PSD. IL-10 protein concentration was not altered in either depot, and TNF-α levels decreased in MEAT. Glucose, triglycerides (TG), VLDL and leptin decreased in serum after 96 hours of PSD; adiponectin was not altered and corticosterone was increased.PSD decreased fat mass and may modulate the cytokine content in different depots of adipose tissue. The inflammatory response was diminished in both depots of adipose tissue, with increased IL-6 levels in RPAT and decreased TNF-α protein concentrations in MEAT and increased levels of corticosterone in serum.A large body of evidence has shown that prolonged paradoxical sleep deprivation (PSD) leads to a reduction in body mass, elevated energy metabolism, changes in circulating hormones, loss of immune integrity, and other disorders [1,2]. Moreover, sleep deprivation has produced hyperphagia, weight loss, increased energy expenditure, increased in plasma catecholamine concentration, hypothyroidism, reduction in core temperature, deterioration in physical appearance [3], and reduced levels of anabolic hormones [4]. Importantly, as the occurrence of sleep disturbances increases in modern lifestyles, so too does the risk of cardiovascular disease [5].PSD induces an inflammatory response with increases in serum pro-inflammatory cytokines [6,7]. Seventy-two hours of PSD increased TNF-α, IL-6, IL-1α and IL-1β levels in the sera of ra
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