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Search Results: 1 - 10 of 121430 matches for " Ryan T. Pohlig "
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Cultural Sensitivity Associated with Domestic Travel Study Program: Long-Term Impact  [PDF]
Jessica R. Eosso, Marie Fanelli Kuczmarski, Ryan T. Pohlig, Laura M. Lessard, Sandra D. Baker
Creative Education (CE) , 2019, DOI: 10.4236/ce.2019.101008
Abstract: Domestic and international travel study programs have grown in length and popularity since they began in 1923. Regardless of the field of study, the goal of most programs is to enhance student cultural sensitivity. The purpose of this study was to explore the contribution of an undergraduate food-focused domestic travel study program on long-term cultural sensitivity based on the ASKED model. A travel study program focused on transcultural food and cuisine was initiated in 1987 and as of 2017, implemented 22 times. The program length varied between 3 and5 weeks and was offered in two locations in the United States. A survey developed to explore the long-term impact of the program incorporated the ASKED model of cultural competence. This model includes five domains: cultural awareness, skill, knowledge, encounters, and desire. The survey was validated and found to be reliable. University of Delaware alumni who participated in the travel study program (n = 461) and a comparison group of alumni (n = 402) who did not participate in the program were invited to complete the survey. The majority of respondents majored in nutrition and dietetics. Alumni who participated in the travel study program had significantly higher total cultural sensitivity scores and also higher scores on 3 domains, namely cultural skill, knowledge, and desire compared to those that did not. Of the 11 program activities participants were asked to rank as contributors to cultural sensitivity, dining experiences and farm to table tours were rated as the top two, respectively. The study findings provided evidence that a short-term, domestic travel study program enhanced long-term cultural sensitivity. Since domestic programs may be a more cost-effective option and align more closely with employment opportunities in healthcare than international travel programs for college graduates, educators should provide opportunities and encourage dietetic students to participate in these travel programs.
Are There Sex Differences in Reaction to Different Types of Sexual Infidelity?  [PDF]
T. Joel Wade, Ryan Kelley, Dominique Church
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.32024
Abstract: Evolutionary theory based research shows that women and men can differ in their responses to sexual and emotional infidelity. However, research has not examined the question of whether men and women react similarly or differently to a partner’s engagement in different types of sexual infidelity. The present research sought to answer this question. Based on the aforementioned prior research, and short term mating desires, sex differences in reactions to different types of sexual infidelity were not expected. Both women and men were expected to report higher levels of upset when a partner engaged in sexual intercourse rather than when a partner engaged in oral sex, heavy petting, or kissing with another person. The results were consistent with the hypothesis. Both men and women were most upset by a partner’s engagement in sexual intercourse with another person. These findings are discussed in terms of prior research.
The Cholera Pandemic, Still with Us after Half a Century: Time to Rethink
Edward T. Ryan
PLOS Neglected Tropical Diseases , 2011, DOI: 10.1371/journal.pntd.0001003
Management Revolution, Market Fetishism and Non-Standard Labour: Implications for Knowledge Workers.
Ryan T. Devitt.
Nebula , 2004,
Interview with Kevin T. Ryan, Harvard University
Kevin T. Ryan
Caucasian Review of International Affairs , 2008,
Optogenetic dissection of amygdala functioning
Ryan T. LaLumiere
Frontiers in Behavioral Neuroscience , 2014, DOI: 10.3389/fnbeh.2014.00107
Abstract: Studies of amygdala functioning have occupied a significant place in the history of understanding how the brain controls behavior and cognition. Early work on the amygdala placed this small structure as a key component in the regulation of emotion and affective behavior. Over time, our understanding of its role in brain processes has expanded, as we have uncovered amygdala influences on memory, reward behavior, and overall functioning in many other brain regions. Studies have indicated that the amygdala has widespread connections with a variety of brain structures, from the prefrontal cortex to regions of the brainstem, that explain its powerful influence on other parts of the brain and behaviors mediated by those regions. Thus, many optogenetic studies have focused on harnessing the powers of this technique to elucidate the functioning of the amygdala in relation to motivation, fear, and memory as well as to determine how the amygdala regulates activity in other structures. For example, studies using optogenetics have examined how specific circuits within amygdala nuclei regulate anxiety. Other work has provided insight into how the basolateral and central amygdala nuclei regulate memory processing underlying aversive learning. Many experiments have taken advantage of optogenetics’ ability to target either genetically distinct subpopulations of neurons or the specific projections from the amygdala to other brain regions. Findings from such studies have provided evidence that particular patterns of activity in basolateral amygdala (BLA) glutamatergic neurons are related to memory consolidation processes, while other work has indicated the critical nature of amygdala inputs to the prefrontal cortex and nucleus accumbens (NA) in regulating behavior dependent on those downstream structures. This review will examine the recent discoveries on amygdala functioning made through experiments using optogenetics, placing these findings in the context of the major questions in the field.
Fibroblasts in fibrosis: novel roles and mediators
Ryan T. Kendall
Frontiers in Pharmacology , 2014, DOI: 10.3389/fphar.2014.00123
Abstract: Fibroblasts are the most common cell type of the connective tissues found throughout the body and the principal source of the extensive extracellular matrix (ECM) characteristic of these tissues. They are also the central mediators of the pathological fibrotic accumulation of ECM and the cellular proliferation and differentiation that occurs in response to prolonged tissue injury and chronic inflammation. The transformation of the fibroblast cell lineage involves classical developmental signaling programs and includes a surprisingly diverse range of precursor cell types—most notably, myofibroblasts that are the apex of the fibrotic phenotype. Myofibroblasts display exaggerated ECM production; constitutively secrete and are hypersensitive to chemical signals such as cytokines, chemokines, and growth factors; and are endowed with a contractile apparatus allowing them to manipulate the ECM fibers physically to close open wounds. In addition to ECM production, fibroblasts have multiple concomitant biological roles, such as in wound healing, inflammation, and angiogenesis, which are each interwoven with the process of fibrosis. We now recognize many common fibroblast-related features across various physiological and pathological protracted processes. Indeed, a new appreciation has emerged for the role of non-cancerous fibroblast interactions with tumors in cancer progression. Although the predominant current clinical treatments of fibrosis involve non-specific immunosuppressive and anti-proliferative drugs, a variety of potential therapies under investigation specifically target fibroblast biology.
Subarachnoid and Peripheral Nerve Block in a Patient with Charcot-Marie-Tooth Disease  [PDF]
Stinson T. Ritter, Ryan J. Jense, Joanna M. Davies
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.31012

Charcot-Marie-Tooth disease (CMT) is a hereditary peripheral neuropathy characterized by progressive distal muscle weakness and wasting. If conservative treatment fails, or is not appropriately initiated, deformity, immobility and chronic pain may result. In severe cases, surgical intervention may be required. With the exception of case reports and case series, limited safety and efficacy data exists regarding the use of neuraxial and regional anesthesia for patients with CMT. This paper describes an anesthetic case report of a patient with CMT, and also provides a review of general and regional anesthetic considerations for this cohort. The purpose of this report is to highlight the potential benefits of neuraxial and regional anesthesia in patients with neuromuscular disorders, especially in settings where intra- and post-operative resources may be limited.

Organic acid toxicity, tolerance, and production in Escherichia coli biorefining applications
Tanya Warnecke, Ryan T Gill
Microbial Cell Factories , 2005, DOI: 10.1186/1475-2859-4-25
Abstract: Biorefining promises the development of efficient processes for the conversion of renewable sources of carbon and energy into large volume commodity chemicals. It has been estimated that such bioprocesses already account for 5% of the 1.2 trillion dollar US chemical market [1], with some projecting future values of up to 50% of the total US chemical market generated through biological means. While the attractiveness of such bioprocesses has been recognized for some time [2,3], recent advances in biological engineering and associated sciences [4-15], several biorefining success stories [16-18], and instability in the price and future availability of oil [19], have collectively reinvigorated interest in the large scale production of chemicals through biological routes. Nevertheless, many challenges still remain for the economical bio-production of commodity chemicals. Such challenges encompass the need to not only inexpensively convert biomass into usable sources of carbon and energy but also to engineer microbes to produce relevant chemicals at high titers and productivities while minimizing the generation of byproducts that might foul downstream processes [1,20,21]. One model for addressing the latter of such challenges involves the generation of platform organisms that can be easily engineered and re-engineered to produce a variety of building block chemicals that are amenable to conversions to higher value products via traditional catalytic routes (see Figure 1). Although chemical pretreatment of raw materials impairs viability of platform organisms, this review will focus on product toxicity issues associated with the production of organic acids in E. coli (for further information on sugar extraction from raw materials see Zaldavar, et al. [22] and Knauf, et al. [23]).The US Department of Energy (USDOE) recently released a prioritized list of building block chemicals for future biorefining endeavors. Priority was assigned based on the projected value of the platf
Bayesian test of normality versus a Dirichlet process mixture alternative
Surya T. Tokdar,Ryan Martin
Statistics , 2011,
Abstract: We propose a Bayesian test of normality of univariate or multivariate data against alternative nonparametric models characterized by Dirichlet process mixture distributions. The alternative models are based on the principles of embedding and predictive matching. They can be interpreted to offer random granulation of a normal distribution into a mixture of normals with mixture components occupying a smaller volume the farther they are from the distribution center. A scalar parametrization based on latent clustering is used to cover an entire spectrum of separation between the normal distributions and the alternative models. An efficient sequential importance sampler is developed to calculate Bayes factors. Simulations indicate the proposed test can detect non-normality without favoring the nonparametric alternative when normality holds.
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