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Search Results: 1 - 10 of 104323 matches for " Ruifang Zhang "
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On Factors Affecting Quality of Sci-tech Journals
刍议影响科技期刊质量的因素

ZHANG RuiFang,
张瑞芳

中国科技期刊研究 , 2006,
Abstract: 面对科技期刊数字化和国际化发展的大趋势,如何进一步提高科技期刊的质量,成为科技期刊界的热门话题。从政治质量、学术质量、编辑质量、印刷出版质量和办刊经费、SCI的影响、论文“出口”等方面,对影响科技期刊质量的因素进行了探讨。指出每一种科技期刊编辑只要理清影响所办期刊质量提高的因素,就能制定出提高质量的对策,就能使科技期刊的质量得到提高。
Finite $p$-groups with a minimal non-abelian subgroup of index $p$ (IV)
Lijian An,Ruifang Hu,Qinhai Zhang
Mathematics , 2013, DOI: 10.1142/s0219498814500327
Abstract: In this paper, we completely classify the finite $p$-groups $G$ such that $\Phi(G')G_3\le C_p^2$, $\Phi(G')G_3\le Z(G)$ and $G/\Phi(G')G_3$ is minimal non-abelian. This paper is a part of the classification of finite $p$-groups with a minimal non-abelian subgroup of index $p$. Together with other four papers, we solve a problem proposed by Y. Berkovich.
The Global Challenge of Antimicrobial Resistance: Insights from Economic Analysis
Karen Eggleston,Ruifang Zhang,Richard J. Zeckhauser
International Journal of Environmental Research and Public Health , 2010, DOI: 10.3390/ijerph7083141
Abstract: The prevalence of antimicrobial resistance (AR) limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.The prevalence of antimicrobial resistance (AR) limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.
The Role of Pharmacists in Perioperative Antibiotic Application in a Hospital of Traditional Chinese Medicine (TCM)  [PDF]
Ruifang Xie, Zhicheng Li, Lingqi Zhu, Yun Zhang, Jie Shen, Xin Zhou
Pharmacology & Pharmacy (PP) , 2014, DOI: 10.4236/pp.2014.53030
Abstract:

Objective: To determine adherence to Chinese guidelines for perioperative antibiotic use in our hospital of TCM and discuss the role of pharmacists on antibiotic management. Methods: 2844 operative cases between May 2011 and December 2011 in our hospital were investigated by pharmacists and relative data were collected, including demographic data, type of surgery, wound classification (clean and clean contaminated) and parameters of antibiotic application (antibiotic choice, route, dose, time of first dose, time of operative re-dosing and duration of prophylaxis). The rationality of antibiotic administration in these cases was respectively evaluated based on Chinese guidelines for perioperative antibiotic use. Results: After intervention of pharmacists, perioperative antibiotic application in our hospital was obviously improved from May to December of 2011: the rates of antibiotic application in operative cases and antibiotic prophylaxis in clean operation were both decreased. However, there was no significant improvement for the rate of rationality. In detail, TCM surgery was well compliant with the guidelines: the rate of antibiotic application was less than 30%, regimen of antibiotic prophylaxis and therapy was reasonable; in the breast ward, antibiotic application was improved after pharmacists intervention: the rate of antibiotic prophylaxis in clean operation significantly decreased from 100% to 30%; however, in the anorectal ward, some troubles were resolved while other new problems came out; in other ward such as general surgery and orthopedics, old problems still existed. Conclusions: Protocol violations were frequent to perioperative antibiotic application in our hospital due to considerable over prescription. Intervention was effective but not enough. Further educational strategies are essential for reducing costs and antibiotic resistance rates.

Response of Subcutaneous Xenografts of Endometrial Cancer in Nude Mice to Inhibitors of Phosphatidylinositol 3-Kinase/Akt and Mitogen-Activated Protein Kinase (MAPK) Pathways: An Effective Therapeutic Strategy for Endometrial Cancer  [PDF]
Ruixia Guo, Xinyan Wang, Ruifang Zhang, Huirong Shi, Yuhuan Qiao, Wenjing Yun, Xin Ge, Yan Lin, Jia Lei
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.612118
Abstract: Objective: This study was designed to explore whether inhibition of the extracellular-regulated kinase (ERK) and phosphatidylinositol-3-kinase (PI3K) signaling pathways can inhibit the growth of xenografts of endometrial cancer cell lines with different estrogen receptors (ER) profiles in vivo and to provide preliminary laboratory basis for the probability of endometrial adenocarcinoma treatment with blockage of the two pathways, especially to endometrial cancer with low ER status. Methods: Human endometrial cancer Ishikawa bearing ER and HEC-1Awith low ER status cells were subcutaneously injected into BALB/c nude mice to establish endometrial cancer xenograft tumor models. The effects of PI3K/Akt inhibitor LY294002, MAPK/ERK1/2 inhibitor PD-98059 and their combinations on the growth of the xenograft tumors and apoptotic state of Ishikawa and HEC-1Acells were tested in vivo using the inhibitory rate, the terminal deoxynucleotidyl transferase-mediated nick-end labeling assay, H/E-stain. Western blot analysis was used to detect the alterations of activated ERK (P-ERK) and AKT (P-AKT) during this process. Results: LY294002, a PI3K/Akt pathway inhibitor, induced significant suppression in the growth of both Ishikawa and HEC-1Acell xenograft tumors, concomitant with increased apoptosis in xenografts as evidenced by TUNEL. A similar effect was also observed when the MAPK/ERK1/2 signaling pathway was inhibited by PD98059. Concurrent inhibition of the PI3K/Akt and MAPK/ERK1/2 pathways showed enhanced anti-tumor effects in vivo as indicated by increased apoptosis. At the same time, the levels of P-ERK and P-AKT in both xenograft tumors decreased, and their levels in combination group was the lowest. Conclusions: PD98059, LY294002 and their combinations showed remarkable inhibitory effects on xenograft tumors of endometrial carcinoma cell lines with different expression status of ER in vivo through blockage of PI3K/Akt and MAPK/ERK1/2 signaling pathways. This suggests that targeting these pathways may be an effective therapeutic strategy against endometrial carcinomas, especially for ER-negative cancers which show poor response to endocrinal therapy.
The Effect of a Psycho-Educational Intervention on Quality of Life of Patients with Advanced Lung Cancer Undergoing Chemotherapy  [PDF]
Yanli Zhao, Ruifang Zhu
Open Journal of Nursing (OJN) , 2015, DOI: 10.4236/ojn.2015.510089
Abstract: Objective: Cancer patients undergoing chemotherapy commonly experience depression and anxiety, which, along with adverse effects of chemotherapy, inevitably compromise quality of life (QOL) of the patients. The aim of this study was to investigate the effect of a psycho-educational intervention on the quality of life (QOL) of patients with advanced lung cancer undergoing chemotherapy. Methods: Two hundred in-patients with unresectable advanced lung cancer undergoing chemotherapy in Shanxi Cancer Hospital from January to October 2013 were randomized into the intervention group (n = 100) and the control group (n = 100). Patients in the intervention group received a purposely designed and nurse-delivered psycho-educational intervention in addition to routine caring and chemotherapy, whereas those in the control group underwent chemotherapy and routine caring only. QOL of patients was assessed according to QOL instrument for lung cancer (QLICP-LU). The impact of the psycho-educational intervention on QOL was analyzed using independent-sample t test and χ2 test. Results: The psychological, physical, and social function, and the overall QOL scores were significantly improved in patients who received the psycho-educational intervention compared with those in the control group. Conclusions: A nurse-delivered psycho-educational intervention is a useful strategy to improve QOL of patients with advanced lung cancer undergoing chemotherapy.
Antibiotic resistance as a global threat: Evidence from China, Kuwait and the United States
Ruifang Zhang, Karen Eggleston, Vincent Rotimi, Richard J Zeckhauser
Globalization and Health , 2006, DOI: 10.1186/1744-8603-2-6
Abstract: We study the recent patterns of antibiotic resistance in three geographically separated, and culturally and economically distinct countries – China, Kuwait and the United States – to gauge the range and depth of this global health threat, and its potential for growth as globalization expands. Our primary measures are the prevalence of resistance of specific bacteria to specific antibiotics. We also propose and illustrate methods for aggregating specific "bug-drug" data. We use these aggregate measures to summarize the resistance pattern for each country and to study the extent of correlation between countries' patterns of drug resistance.We find that China has the highest level of antibiotic resistance, followed by Kuwait and the U.S. In a study of resistance patterns of several most common bacteria in China in 1999 and 2001, the mean prevalence of resistance among hospital-acquired infections was as high as 41% (with a range from 23% to 77%) and that among community- acquired infections was 26% (with a range from 15% to 39%). China also has the most rapid growth rate of resistance (22% average growth in a study spanning 1994 to 2000). Kuwait is second (17% average growth in a period from 1999 to 2003), and the U.S. the lowest (6% from 1999 to 2002). Patterns of resistance across the three countries are not highly correlated; the most correlated were China and Kuwait, followed by Kuwait and the U.S., and the least correlated pair was China and the U.S.Antimicrobial resistance is a serious and growing problem in all three countries. To date, there is not strong international convergence in the countries' resistance patterns. This finding may change with the greater international travel that will accompany globalization. Future research on the determinants of drug resistance patterns, and their international convergence or divergence, should be a priority.In 1942, the first U.S. patient with streptococcal infection was miraculously cured with a small dose of penicilli
Improving analytic hierarchy process applied to fire risk analysis of public building
Long Shi,RuiFang Zhang,QiYuan Xie,LiHua Fu
Chinese Science Bulletin , 2009, DOI: 10.1007/s11434-009-0056-z
Abstract: The structure importance in Fault Tree Analysis (FTA) reflects how important Basic Events are to Top Event. Attribute at alternative level in Analytic Hierarchy Process (AHP) also reflect its importance to general goal. Based on the coherence of these two methods, an improved AHP is put forward. Using this improved method, how important the attribute is to the fire safety of public building can be analyzed more credibly because of the reduction of subjective judgment. Olympic venues are very important public buildings in China. The fire safety evaluation of them will be a big issue to engineers. Improved AHP is a useful tool to the safety evaluation to these Olympic venues, and it will guide the evaluation in other areas.
Improving analytic hierarchy process applied to fire risk analysis of public building

Long Shi,RuiFang Zhang,QiYuan Xie,LiHua Fu,

科学通报(英文版) , 2009,
Abstract: The structure importance in Fault Tree Analysis (FTA) reflects how important Basic Events are to Top Event. Attribute at alternative level in Analytic Hierarchy Process (AHP) also reflect its importance to general goal. Based on the coherence of these two methods, an improved AHP is put forward. Using this improved method, how important the attribute is to the fire safety of public building can be analyzed more credibly because of the reduction of subjective judgment. Olympic venues are very important public buildings in China. The fire safety evaluation of them will be a big issue to engineers. Improved AHP is a useful tool to the safety evaluation to these Olympic venues, and it will guide the evaluation in other areas. Support by the National Natural Science Foundation of China (Grant No. 50536030), National Project of Scientific and Technical Supporting Programs funded by Ministry of Science & Technology of China (Grant No. 2006BAK06B02) and China Postdoctoral Science Foundation (Grant No. 20070410220)
Cross-domain Authentication Alliance Protocol Based on Isomorphic Groups
Qikun Zhang,Jun Zheng,Yuan Tan,Ruifang Wang
Journal of Computers , 2011, DOI: 10.4304/jcp.6.4.650-656
Abstract: With the development of information technology in distributed network, such as cloud computing and grid computing. They need mutual coordination resources among the various areas to meet the requirement in infinite speed and infinite space of information technology for people. To ensure secure access resources among areas, the paper proposes a cross-domain authentication alliance-agreement. This agreement constructs a large prime group over elliptic curve, and uses direct product decomposition of the large prime group to construct multiple automorphism groups. Each automorphism group is made as a different key parameter in different domains to overcome the defect of key parameters consistency in the alliance-domain of the existing programs, and all the members must register with blinded keys in their domains to avoid the authority faking the members to cross-domain access resources of the existing programs, and uses the bilinear automorphism group for inter-domain signcrypt to achieve the cross-domain alliance certification, to overcome the complexity of certificate transmission and bottlenecks in the scheme of PKI-based. Analyses show that this scheme has anonymity, security and supporting mutual anonymous authentication.
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