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Search Results: 1 - 10 of 7758 matches for " Rosane Marina Peralta "
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Adequa??o do suporte nutricional na terapia nutricional enteral: compara??o em dois hospitais
Nozaki, Vanessa Taís;Peralta, Rosane Marina;
Revista de Nutri??o , 2009, DOI: 10.1590/S1415-52732009000300004
Abstract: objective: the objective of this study was to assess the nutritional status of inpatients and compare the enteral feeding practices of two general hospitals in the metropolitan region of maringá (pr), brazil. methods: the study included 62 patients of both sexes on exclusive enteral feeding. the data were collected in two general hospitals. the energy requirements of the patients were estimated using the equations proposed by harris & benedict and the european society for clinical nutrition and metabolism recommendation. the nutritional status of the patients was determined by anthropometric assessment. results: high rates of malnutrition were found in both hospitals, especially when the mid-arm muscle area was used as the indicator of nutritional status. the energy prescription was adequate for 45.71% and 40.74% of the patients of hospitals 1 and 2, respectively. conclusion: inadequate enteral feeding associated with high rates of malnutrition was found in both hospitals. the data obtained in this study show that both enteral feeding services need improvements. standardization of enteral feeding practices and regular patient assessment are also needed.
Estudo comparativo da adequa o das prescri es e ofertas protéicas a pacientes em uso de terapia nutricional enteral = Comparative study on the adequacy of protein prescription and supply to patients undergoing enteral nutritional therapy
Vanessa Taís Nozaki,Rosane Marina Peralta
Acta Scientiarum : Health Sciences , 2008,
Abstract: O objetivo desse estudo foi de avaliar as prescri es e ofertas protéicas a pacientes em uso de terapia nutricional enteral em dois hospitais da regi o metropolitana de Maringá, Estado do Paraná. Como metodologia utilizou-se os valores prescritos e o consumo de proteínas pelos pacientes foram obtidos dos prontuários médicos e comparados com as recomenda es de consumo diário de proteínas por quilo de peso corporal para cada patologia. Os principais resultados dessa pesquisa foram que apenas 11,43% das dietas prescritas no Hospital A e 22,22% das dietas prescritas no Hospital B estavam corretas com rela o à quantidade recomendada de proteínas. Nos dois hospitais, apenas 11% dos pacientes ingeriram a quantidade diária recomendada de proteínas. Pode-se concluir que a terapia nutricional enteral inadequada foi encontrado nos dois hospitais. Este estudodemonstrou a necessidade de melhoras nos servi os de nutri o enteral. Isto pode ser conseguido adotando-se procedimentos de padroniza o e avalia o regulares dos pacientes. The aim of this study was to evaluate protein prescription and supply to patients undergoing enteral nutritional therapy at two general hospitals in Maringá, Paraná State, Brazil. How methodology used isthe prescribed protein values and protein intake of each patient were obtained from medical records, and compared with the recommended daily protein intake per kilogram of body weight for each pathology. The main results of this survey were that only 11.43% of theprescribed diets in Hospital A and 22.22% of the prescribed diets in Hospital B were correct with respect to recommended protein amounts. In both hospitals, only 11% of all patients ingested the daily recommended amount of protein. It was concluded inadequate enteralnutritional therapy was found in both hospitals. The study demonstrates a need for improvement in enteral nutrition practices. This can be accomplished through the adoption of standardization procedures and periodic patient evaluation.
Effects of Ranolazine on Carbohydrate Metabolism in the Isolated Perfused Rat Liver  [PDF]
Márcio Shigeaki Mito, Cristiane Vizioli de Castro, Rosane Marina Peralta, Adelar Bracht
Open Journal of Medicinal Chemistry (OJMC) , 2014, DOI: 10.4236/ojmc.2014.44007
Abstract: The action mechanism of ranolazine, an antiangina drug, could be at least partly metabolic, including inhibition of fatty acid oxidation and stimulation of glucose utilization in the heart. The purpose of the present work was to investigate if ranolazine affects hepatic carbohydrate metabolism. For this purpose, the hemoglobin-free isolated perfused rat liver was used as the experimental system. Ranolazine increased glycolysis and glycogenolysis and decreased gluconeogenesis. These effects were accompanied by an inhibition of oxygen consumption. The drug also changed the redox state of the NAD+-NADH couple. For the cytosol, increased NADH/NAD+ ratios were observed both under glycolytic conditions as well as under gluconeogenic conditions. For the mitochondria, increased NADH/NAD+ ratios were found in the present work in the absence of exogenous fatty acids in contrast with the previous observation of a decreasing effect when the liver was actively oxidizing exogenous oleate. It seems likely that ranolazine inhibits gluconeogenesis and increases glycolysis in consequence of its inhibitory actions on energy metabolism and fatty acid oxidation and by deviating reducing equivalents in favour of its own biotransformation. This is in line with the earlier postulates that ranolazine diminishes fatty acid oxidation, shifting the energy source from fatty acids to glucose.
Effects of Arterially Infused Hydroalcoholic Agaricus blazei Extracts on Perfusion Pressure and Oxygen Uptake in the Bivascularly Perfused Rat Liver  [PDF]
Andrea Luiza de Oliveira Valoto, Jorgete Constantin, Fabrício Bracht, Rosane Marina Peralta, Adelar Bracht
Journal of Biosciences and Medicines (JBM) , 2015, DOI: 10.4236/jbm.2015.310010
Abstract: In a preceding work we have reported experiments showing that an hydroalcoholic exctract of Agaricus blazei is able to exert purinergic effects in the isolated perfused rat liver when it is infused into the portal vein in monovascular perfusion (entry: portal vein; exit: hepatic vein). In the present communication we are presenting and discussing experiments done with the bivascularly perfused rat liver (entry: portal vein + hepatic artery; exit: hepatic vein) in order to verify if the hemodynamic effects also occur in the arterial bed. It was found that the A. blazei extract is also active when infused into the hepatic arterial bed, with differences in both sensitivity and nature of the effects on either perfusion pressure or oxygen consumption. Constriction of the arterial bed required much higher concentrations of the extract than the portal bed. The kinetics of the response was also different, with a biphasic instead of a monophasic response. These results provide a promising starting point for future studies aiming to bring to light more mechanistic details about these and possibly other effects.
Production of Enzymes and Biotransformation of Orange Waste by Oyster Mushroom, Pleurotus pulmonarius (Fr.) Quél.  [PDF]
Fabíola Dorneles Inácio, Roselene Oliveira Ferreira, Caroline Aparecida Vaz de Araujo, Rosane Marina Peralta, Cristina Giatti Marques de Souza
Advances in Microbiology (AiM) , 2015, DOI: 10.4236/aim.2015.51001
Abstract: The wood-decay fungi are able to bioconvert a wide variety of lignocellulosic residues due to the secretion of extracellular enzymes. The use of agricultural wastes as substrate for mushroom cultivation or enzymes production can help to solve environmental problems caused by inadequate discharge in the nature. The production of hydrolytic and oxidative enzymes by Pleurotus pulmonarius developed in solid state system using orange waste as substrate was evaluated in this work. Among the hydrolytic enzymes, pectinase was the main enzyme produced by the fungus, presenting the highest enzymatic activity of 9.4 U/mL after 35 days of cultivation. Considering the oxidative enzymes, laccase was the main enzyme produced with maximal activity of 12.2 U/mL obtained after 20 days of cultivation. Low enzyme levels of manganese peroxidase, β-glucosidase and β-xy-losidase were detected with activity peaks at the end of the cultivation. The enzymatic levels of amylase, carboxymethyl cellulase and xylanase were similar and less than 1.5 U/mL. No aryl-alcohol oxidase activity was detected. NDF, ADF and cellulose values increased during 45 days of cultivation. There was no lignin degradation during the study period and the fungus culture in orange solid waste caused protein enrichment in the substrate. Our results demonstrate that P. pulmonarius was an efficient producer of two important industrial enzymes, pectinase and laccase in a cheap solid state system using orange waste as substrate.
The Action of p-Synephrine on Lipid Metabolism in the Perfused Rat Liver  [PDF]
Juliany Fontoura da Silva-Pereira, Andrea Luiza de Oliveira Valoto, Lívia Bracht, Geferson de Almeida Gon?alves, Rosane Marina Peralta, Adelar Bracht
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.55002
Abstract: p-synephrine and p-octopamine were found to increase lipolysis in adipocytes. The present study approaches the question if these compounds, natural products of the bitter orange (Citrus aurantium fruit), increase lipolysis and fatty acid oxidation in the liver. Experiments were done in the perfused rat liver. Non-recirculating hemoglobin-free perfusion was done using the Krebs/ Henseleit-bicarbonate buffer (pH 7.4) as perfusion fluid. Both p-synephrine and p-octopamine, at the concentrations of 100 μM, were found to stimulate the hepatic triacylglycerol lipase by 40% and 51%, respectively. These seem to be the maximal stimulations possible in the liver. In the perfused liver, p-synephrine, when present at an initial concentration of 500 μM, was able to increase the non-esterified fatty acid release after one hour of recirculating perfusion. The effects of p-synephrine on the oxidation of exogenously supplied [1-14C]octanoate and [1-14C]oleate were minimal. Only oxygen uptake, already stimulated by octanoate or oleate, was additionally increased by the infusion of p-synephrine. These results contrast with those obtained in a previous study with p-octopamine, which increased the production of 14CO2 from both [1-14C]octanoate and [1-14C]oleate. Apparently only the oxidation of endogenous fatty acids is stimulated by p-synephrine. On the other hand, both p-synephrine and p-octopamine stimulate the hepatic triacylglycerol lipase to a much lesser extent than the adipocyte lipase. It can be concluded that p-synephrine affects much more carbohydrate metabolism in the liver than lipid metabolism.
Production of tannase by Aspergillus tamarii in submerged cultures
Costa, Andréa M.;Ribeiro, Wanessa X.;Kato, Elaine;Monteiro, Antonio Roberto G.;Peralta, Rosane Marina;
Brazilian Archives of Biology and Technology , 2008, DOI: 10.1590/S1516-89132008000200021
Abstract: the production of tannase by aspergillus tamarii was studied in submerged cultures. the fungus produced an extracellular tannase after two days of growth in mineral medium containing tannic acid, gallic acid and methyl gallate as carbon source. the best result was obtained using gallic acid as inducer (20.6 u/ml). the production of enzyme was strongly repressed by the presence of glucose. crude enzyme was optimally active at ph 5.0 and 30o c. the enzyme was stable in a large range of ph and up to the temperature of 45o c.
Aproveitamento do resíduo de laranja para a produ??o de enzimas lignocelulolíticas por Pleurotus ostreatus (Jack:Fr)
Alexandrino, Ana Maria;Faria, Haroldo Garcia de;Souza, Cristina Giatti Marques de;Peralta, Rosane Marina;
Ciência e Tecnologia de Alimentos , 2007, DOI: 10.1590/S0101-20612007000200026
Abstract: in this work, orange waste as a substrate to produce hydrolytic and oxidative enzymes involved in the degradation of ligninocellulolytic materials, such as laccase (ec, manganese peroxidase (ec, xylanase (ec and endo-1,4 glucanase (ec by the basidiomycete pleurotus ostreatus was used. the fungus was able to grow in the orange waste at different moisture contents without any supplementation. the orange waste medium provided the conditions to produce high activities of important industrial enzymes, especially laccase (75 u.g -1 substrate, after 15 days of cultivation) and mn peroxidase (6.8 u.g -1 substrate, after 30 days of cultivation).
Produ??o de inóculo do cogumelo comestível Pleurotus pulmonarius (Fr.) Quélet - CCB19 a partir de resíduos da agroindústria
Oliveira, Mariana Alves de;Donega, Mateus Augusto;Peralta, Rosane Marina;Souza, Cristina Giatti Marques de;
Ciência e Tecnologia de Alimentos , 2007, DOI: 10.1590/S0101-20612007000500015
Abstract: edible mushrooms are appreciated for their taste and nutritional qualities. lignocellulosic wastes are excellent substrates for their production and mycelium propagation (inoculum or spawn). the aim of this work was to evaluate three agricultural residues: rice straw, corncob and peanut husk to produce pleurotus pulmonarius ccb19 spawn. the spawns were inoculated in bags containing 150 g of a mixture of wheat bran:corn husk:peanut husk (5:2:3). the fruit bodies were harvested from the substrate and biological efficiencies, yield and size were calculated. the rice straw spawn produced the highest body fruit, showing a biological efficiency of 43%. however, the least time for fructification was with corncob powder spawn. larger mushrooms were obtained when rice straw was used as spawn. the means of the eb were 28 and 23% in corn cob and peanut husk, respectively.
Digestibilidade de Duas Fontes de Amido e Atividade Enzimática em Coelhos de 35 e 45 Dias de Idade
Toral Fábio Luiz Buranelo,Furlan Antonio Claudio,Scapinello Cláudio,Peralta Rosane Marina
Revista Brasileira de Zootecnia , 2002,
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