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Search Results: 1 - 10 of 1845 matches for " Ron Wald "
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Frequency and factors influencing publication of abstracts presented at three major nephrology meetings
Ziv Harel, Ron Wald, Ari Juda, Chaim M Bell
International Archives of Medicine , 2011, DOI: 10.1186/1755-7682-4-40
Abstract: 300 randomly selected abstracts presented as posters at three annual nephrology meetings in 2006 [American Society of Nephrology (ASN), European Renal Association (ERA), and National Kidney Foundation (NKF)] were reviewed. Accepted methods of literature search were performed to determine subsequent journal publication. Univariate and multivariate analyses were performed to determine the association between abstract characteristics and subsequent full publication.127 (42%) abstracts were published in peer-reviewed journals at 4.5 years. On multivariable analysis, basic science research (OR 2.84, 95% CI 1.44-5.61 as compared to clinical research) and the scientific meeting [OR 2.87, 95% CI 1.60-5.15 (ASN); OR 1.92, 95% CI 1.07-3.45(ERA) as compared to NKF] were significantly associated with full publication.Almost two-fifths of abstracts presented at three major nephrology meetings are subsequently published in peer-reviewed journals. Basic science content and the meeting at which the abstract was presented are associated with publication. Further research is needed to ascertain the impact of other important factors on abstract publication rates to address publication bias in the renal literature.Presentations of abstracts at national and international scientific meetings provide a forum for the rapid dissemination of novel research. Subsequent publication of an abstract in a peer-reviewed journal may reflect the validity and importance of the results contained within the abstract and the impact of the meeting at which the abstract is presented [1,2]. However, over half of all abstracts presented at scientific meetings are not subsequently published in peer reviewed journals [3]. Reasons cited for poor publication rates include: small sample size, a negative result, lack of author motivation to publish, and a non-experimental study design [3-6]. While many medical disciplines have reported on abstract publication rates and the factors associated with peer-review publi
Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis
Jan O Friedrich, Ron Wald, Sean M Bagshaw, Karen EA Burns, Neill KJ Adhikari
Critical Care , 2012, DOI: 10.1186/cc11458
Abstract: MEDLINE, EMBASE and CENTRAL databases and conference abstracts were searched to June 2012 for parallel-group or crossover randomized and quasi-randomized controlled trials (RCTs) evaluating hemofiltration vs. hemodialysis in patients with AKI. Two authors independently selected studies and abstracted data on study quality and outcomes. Additional information was obtained from trial authors. We pooled data using random-effects models.Of 6,657 citations, 19 RCTs (10 parallel-group and 9 crossover) met inclusion criteria. Sixteen trials used continuous RRT. Study quality was variable. The primary analysis included three parallel-group trials comparing similar doses of hemofiltration and hemodialysis; sensitivity analyses included trials comparing combined hemofiltration-hemodialysis or dissimilar doses. We found no effect of hemofiltration on mortality (risk ratio (RR) 0.96, 95% confidence interval (CI) 0.73 to 1.25, P = 0.76; three trials, n = 121 (primary analysis); RR 1.10, 95% CI 0.88 to 1.38, P = 0.38; eight trials, n = 540 (sensitivity analysis)) or other clinical outcomes (RRT dependence in survivors, vasopressor use, organ dysfunction) compared to hemodialysis. Hemofiltration appeared to shorten time to filter failure (mean difference (MD) -7 hours, 95% CI (-19,+5), P = 0.24; two trials, n = 50 (primary analysis); MD -5 hours, 95% CI (-10, -1), P = 0.01; three trials, n = 113 (including combined hemofiltration-hemodialysis trials comparing similar doses); MD -6 hours, 95% CI (-10, -1), P = 0.02; five trials, n = 383 (sensitivity analysis)). Data primarily from crossover RCTs suggested that hemofiltration increased clearance of medium to larger molecules, including inflammatory cytokines, compared to hemodialysis, although almost no studies measured changes in serum concentrations. Meta-analyses were based on very limited data.Data from small RCTs do not suggest beneficial clinical outcomes from hemofiltration, but confidence intervals were wide. Hemofiltration
Exploring the impact of a decision support intervention on vascular access decisions in chronic hemodialysis patients: study protocol
Mary Murray, Alison Thomas, Ron Wald, Rosa Marticorena, Sandra Donnelly, Lianne Jeffs
BMC Nephrology , 2011, DOI: 10.1186/1471-2369-12-7
Abstract: A non-experimental intervention study with repeated measures will be conducted at St. Michaels Hospital in Toronto, Canada. Decisional conflict about dialysis access choice will be measured using the validated SURE tool, an instrument used to identify decisional conflict. Thereafter a tailored decision support intervention will be implemented. Decisional conflict will be re-measured and compared with baseline scores. Patients and staff will be interviewed to gain an understanding of how useful this intervention was for them and whether it would be feasible to implement more widely. Quantitative data will be analyzed using descriptive and inferential statistics. Statistical significance of difference between means over time for aggregated SURE scores (pre/post) will be assessed using a paired t-test. Qualitative analysis with content coding and identification of themes will be conducted for the focus group and patient interview data.Coupling the SURE tool with a decision support system structured so that a positive test result triggers providers to help patients through the decision-making process and/or refer patients to appropriate resources could benefit patients and ensure they have the opportunity to make informed HD access choices.Chronic Kidney Disease (CKD) a serious long term illness affecting more than two million Canadians, is a major public health problem[1]. Patients with CKD stage 5 D - also referred to as end-stage kidney failure - require renal replacement therapy (RRT). Diabetes is the leading cause of Stage 5 CKD and 54% of patients requiring RRT in 2007 were over the age of 65. Between 1998 and 2007, there has been a 51% increase in the number of patients with CKD stage 5 D receiving hemodialysis (HD)[2]. The estimated annual cost of hospital based HD (inpatient or outpatient clinic) in Canada per patient in 2002 was $59,476.00 [3].Adults living with Stage 5 CKD face numerous decision points [4]. These patients often experience uncertainty when con
A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis
Constantine J Karvellas, Maha R Farhat, Imran Sajjad, Simon S Mogensen, Alexander A Leung, Ron Wald, Sean M Bagshaw
Critical Care , 2011, DOI: 10.1186/cc10061
Abstract: Systematic review and meta-analysis were used in this study. PUBMED, EMBASE, SCOPUS, Web of Science and Cochrane Central Registry of Controlled Clinical Trials, and other sources were searched in July 2010. Eligible studies selected were cohort and randomised trials that assessed timing of initiation of RRT in critically ill adults with AKI.We identified 15 unique studies (2 randomised, 4 prospective cohort, 9 retrospective cohort) out of 1,494 citations. The overall methodological quality was low. Early, compared with late therapy, was associated with a significant improvement in 28-day mortality (odds ratio (OR) 0.45; 95% confidence interval (CI), 0.28 to 0.72). There was significant heterogeneity among the 15 pooled studies (I2 = 78%). In subgroup analyses, stratifying by patient population (surgical, n = 8 vs. mixed, n = 7) or study design (prospective, n = 10 vs. retrospective, n = 5), there was no impact on the overall summary estimate for mortality. Meta-regression controlling for illness severity (Acute Physiology And Chronic Health Evaluation II (APACHE II)), baseline creatinine and urea did not impact the overall summary estimate for mortality. Of studies reporting secondary outcomes, five studies (out of seven) reported greater renal recovery, seven (out of eight) studies showed decreased duration of RRT and five (out of six) studies showed decreased ICU length of stay in the early, compared with late, RRT group. Early RRT did not; however, significantly affect the odds of dialysis dependence beyond hospitalization (OR 0.62 0.34 to 1.13, I2 = 69.6%).Earlier institution of RRT in critically ill patients with AKI may have a beneficial impact on survival. However, this conclusion is based on heterogeneous studies of variable quality and only two randomised trials. In the absence of new evidence from suitably-designed randomised trials, a definitive treatment recommendation cannot be made.Acute kidney injury (AKI) is a serious complication of critical illness
Elimination of ventilator dead space in premature infants by flow partition: a new method
M Wald
Critical Care , 2004, DOI: 10.1186/cc2481
In Memoriam: Ivan Daskalov: 1933 – 2004
Alvin Wald
BioMedical Engineering OnLine , 2004, DOI: 10.1186/1475-925x-3-22
Abstract: Friendship is a unique human relationship. It is a mutual freely consensual activity between two people. Each friendship is different and inexplicable, and based on its own particulars. When you lose a friend, you lose something special, you lose a part of yourself. But that friendship is not really lost if you pass it on to others.Ivan Daskalov was my friend. He had been ill for a while, so his death was not completely unexpected. Yet I cannot but feel that he should have been here longer. People involved in health care often somehow feel that their work in trying to conquer nature's ineluctable passage gives them and their loved ones immunity from the inevitable fate of us all. After all, that is one reason that many of us became biomedical engineers to begin with.I met Ivan some 15 years ago at an IEEE/EMBS conference. (In truth, I am not sure just how long ago it was.) He made some very gentle comment about my presentation, and we talked for a while. That was the only time that I actually met him in person, and my first impression, which was only reinforced as I came to know him better, was that he was a true gentleman. Over the years we communicated by mail and then mostly by e-mail. Our correspondence covered many topics, but mostly was about the joys and tribulations of life. Our views meshed almost perfectly, despite our growing up in different parts of the world. Maybe it was because we were close contemporaries in time, and as children saw the world through a great war.We exchanged small gifts: I would send him technical journals and he would reciprocate with cultural artifacts from Bulgaria. On occasion, I also sent him some literary magazines He always wanted to improve his English, which I always told him was quite good and in fact much better than my Bulgarian. His basic kindness was again shown as he sent me Bulgarian postage stamps after finding out about a young friend of mine who collects stamps. Ivan was particularly proud of his country. He recog
BioMedical Engineering OnLine: An Editorial
Alvin Wald
BioMedical Engineering OnLine , 2004, DOI: 10.1186/1475-925x-3-16
Abstract: The first issue to consider is why? Why another BME publication? Why an all electronic publication? Why me? The answers I can present will never tell the complete story, but like any good research, can only illuminate a small aspect of reality. Biomedical engineering is growing, and this growth is demonstrated by numerous new publications – each devoted to some recently exploited area of interest – or as the provenance of some new specialized organization based on geographical or technical convergence. While the growth of biomedical engineering is admirable, its fragmentation is not. More and more biomedical engineers become isolated. Publications cost money, in order to obtain print publications, libraries or individuals must either buy a subscription, or join yet another dues collecting organization. Costs have become prohibitive: just ask your library. A large number of biomedical engineers throughout the world thus simply lack access to vast quantities of relevant literature. But development of the world-wide-web has now provided a means to overcome this obstacle of costs. The Internet is providing a means for rapid and low-cost dissemination of technical information. It is the perfect medium by which researchers, rich and poor alike, can share the results of their works. There are no longer any limitations brought about by the high costs in time and money of print and paper production and transportation.Let us look at some of the specific changes in publishing between what was then and what is now. In a previous life, I was the editor of a print publication for many years. It was a rewarding experience at the time, but now with electronic publication the world has once again been rocketed into a new orbit, and a different set of parameters has evolved. Although editors and publishers may have to make some adjustments to this new order, authors will benefit significantly.Consider the costs of traditional publication. Because of expenses associated with physical
Promoción de la salud a través del arte: estudio de caso de un taller de fotografía en "Ciudad Oculta", la villa No 15 de la Ciudad de Buenos Aires
Salud Colectiva , 2009, DOI: 10.1590/S1851-82652009000300004
Abstract: this article analyzes the potentials of community art to promote health and wellbeing among young people living in vulnerable social contexts in latin america. through a case-study, we aim at providing elements for the theoretical and methodological debate of a central problem in health promotion: the distance between its rhetoric, based on a wide conception of health -understood as a collective process, influenced by social, economic, environmental and cultural issues- and the interventions that have been carried out in our region, organized around disease concepts that respond to individualistic theoretical approaches. the selected case is ph15, a photography workshop delivered by a group of photographers in the shanty town no 15 "ciudad oculta" ("hidden city") of the city of buenos aires. the study shows that young people notice individual and collective changes as a result of participating in this workshop, and these changes could be linked to the wide concept of health. therefore, an activity that has not been thought to promote health can help us to design activities that are closer to the philosophy of health promotion.
Kalenderhervorming en 'n skeppingsordinansie
M. Wald
Koers : Bulletin for Christian Scholarship , 1948, DOI: 10.4102/koers.v16i2.1675
Abstract: By die afbrekende magte wat die bestaan van godsdienstige instellingeen historiese tradisies ondermyn, is nou nog ’n verdere ontbindende element gevoeg, naamlik die voorgestelde Kalender-Hervorming. ’n Wêreldwye en magtige organisasie, Wêreld-Kalender-Vereniging, is al gedurende die afgelope tientalle jare besig om te werk vir die aanname van die nuwe Wêreldkalender deur van handels-, regerings- en ander liggame en vir dieafskaffing van die godsdienstige en historiese Joodse Sabbat, die ChristelikeSondag en die Mohammedaanse Vrydag.
Modeling Flow Rate to Estimate Hydraulic Conductivity in a Parabolic Ceramic Water Filter
Ileana Wald
Undergraduate Journal of Mathematical Modeling : One + Two , 2012, DOI: 10.5038/2326-3652.4.2.6
Abstract: In this project we model volumetric flow rate through a parabolic ceramic water filter (CWF) to determine how quickly it can process water while still improving its quality. The volumetric flow rate is dependent upon the pore size of the filter, the surface area, and the height of water in the filter (hydraulic head). We derive differential equations governing this flow from the conservation of mass principle and Darcy's Law and find the flow rate with respect to time. We then use methods of calculus to find optimal specifications for the filter. This work is related to the research conducted in Dr. James R. Mihelcic's Civil and Environmental Engineering Lab at USF.
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