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Search Results: 1 - 10 of 19228 matches for " Richard Teke Ngomba "
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MGluR5 Mediates the Interaction between Late-LTP, Network Activity, and Learning
Arthur Bikbaev, Sergey Neyman, Richard Teke Ngomba, Jeffrey Conn, Ferdinando Nicoletti, Denise Manahan-Vaughan
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002155
Abstract: Hippocampal synaptic plasticity and learning are strongly regulated by metabotropic glutamate receptors (mGluRs) and particularly by mGluR5. Here, we investigated the mechanisms underlying mGluR5-modulation of these phenomena. Prolonged pharmacological blockade of mGluR5 with MPEP produced a profound impairment of spatial memory. Effects were associated with 1) a reduction of mGluR1a-expression in the dentate gyrus; 2) impaired dentate gyrus LTP; 3) enhanced CA1-LTP and 4) suppressed theta (5–10 Hz) and gamma (30–100 Hz) oscillations in the dentate gyrus. Allosteric potentiation of mGluR1 after mGluR5 blockade significantly ameliorated dentate gyrus LTP, as well as suppression of gamma oscillatory activity. CA3-lesioning prevented MPEP effects on CA1-LTP, suggesting that plasticity levels in CA1 are driven by mGluR5-dependent synaptic and network activity in the dentate gyrus. These data support the hypothesis that prolonged mGluR5-inactivation causes altered hippocampal LTP levels and network activity, which is mediated in part by impaired mGluR1-expression in the dentate gyrus. The consequence is impairment of long-term learning.
Stephen Coleman & Karen Ross: The Media and the Public: ‘Them’ and ‘Us’ in Media Discourse. West Sussex: Wiley-Blackwell. 2010.
Teke J Ngomba
MedieKultur : Journal of Media and Communication Research , 2012,
Abstract:
Norma Pecora, Enyonam Osei-Hwere & Ulla Carlsson (Eds.): African media, African children. Gothenburg: The International Clearinghouse on Children, Youth and Media, NORDICOM. 2008
Teke J Ngomba
MedieKultur : Journal of Media and Communication Research , 2010,
Abstract:
Discourses of positionality and the challenges of democratization in the global south: The case of Nepal and Cameroon
Jacob Thorsen,Teke J Ngomba
MedieKultur : Journal of Media and Communication Research , 2012,
Abstract: In this article, we argue that to conceptually and empirically grasp the dynamics and challenges of processes of civic participation, i.e., the deliberation and empowerment of disenfranchised and marginalized populations in the Global South, communication for social change scholars need to pay more attention to three issues: the quality of citizens’ self-perceptions in relation to their local milieu, inter-citizen perceptions and relations at the local level and lastly, the attendant consequences of these on citizens’ sense of efficacy. To grasp and comprehend the interplay of these three issues, we propose the adoption of Floya Anthias’ concept of narratives of location and positionality and demonstrate the heuristic vitality of this notion through a discussion of some local discourses of positionality in Nepal and Cameroon.
Seasonal Variations in Groundwater of the Phreatic Aquiferous Formations in Douala City-Cameroon: Hydrogeochemistry and Water Quality  [PDF]
Richard Ayuk Akoachere, Sonia Ebot Egbe, Thomson Areapkoh Eyong, Sophie Ngomune Edimo, Simon Ngomba Longonje, Diana Besem Tambe, Nji Bihmimihney Nelly
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105328
Abstract:
This study was to determine the seasonal variations of groundwater, the influence of the rock formations on the groundwater solute chemistry and groundwater domestic-agro-industrial quality using hydrogeochemical tools and physicochemical parameters; Ionic ratios, Gibbs diagrams, Piper diagrams, Durov diagrams and water quality indices. From physicochemical parameters; in the rainy season, pH ranged from, 4.6-7.1; EC, 0.023-1.63 mS/cm; Temperature, 26.3-290C andTDS, 0.015-1.09 mg/L and in the dry season pH ranged from 5-7.2; EC, 0.01-1.61 mS/cm; Temperature, 24.4-29.50C andTDS, 0.01-1.08 mg/L. Forty groundwater samples; 20 per season, wet and dry were analysed. Themajor ions fell below WHO acceptable limits for both seasons. The sequences of abundance of major ions were, Ca2 >K >Mg2 >NH4 >Na , HCO3->Cl->SO42->NO3->HPO42- in wet season and Ca2 >Mg2 >K >Na >NH4 , HCO3->Cl->SO42->HPO42->NO3- in dry season. Ion-exchange, simple dissolution and uncommon dissolution processes determined groundwater character. Groundwater ionic content was as a result of ion exchange from rock-weathering. Water types are; MgCl and MgHCO3 in both seasons. Hydrogeochemical facies are; Ca-Mg-Cl-SO4, characteristic of groundwater some distance along its flow path and Ca-Mg-HCO3, characteristic of freshly recharged groundwater from precipitation. The groundwater indices of; Sodium Percent (% Na), Residual Sodium Carbonate (RSC) , Kelley’s ratio (KR), Sodium Adsorption Ratio (SAR), Electrical Conductivity (EC), Total Dissolved Solid (TDS), USSL? and Wilcox index were determined, evaluated and found to be suitable for agro-industrial uses in all seasons. Permeability Index (PI) , Water quality index (WQI) and Magnesium Adsorption Ratio (MAR) were not suitable in some areas and in some seasons.
Trace Metals in Groundwater of the South Eastern Piedmont Region of Mount Cameroon: Quantification and Health Risk Assessment  [PDF]
Richard Ayuk Akoachere, Edwin Ngwene Etone, Roy Lyonga Mbua, Marcelle Pami Ngassam, Simon Ngomba Longonje, Pius Mbu Oben, Regina Wotany Engome
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105327
Abstract:
The South Eastern Piedmont Region of Mount Cameroon is getting in-creasingly populated. Groundwater is the main resource for drinking in this area; hence, the quantification of trace metals, suitability and quality of the groundwater resources for drinking, domestic and agro-industrial uses is of public and scientific concern. In this study, 10 samples were collected from 10 sites in September 2017. Field measurement of physicochemical parameters and investigation of the levels of trace metal content in groundwater was determined using Inductively Coupled Plasma Mass Spectroscopy ICP-MS. R-mode statistical analysis has been done and traces metals elements correlated with the physicochemical parameters and cluster analysis PCA carried out. The paper also highlights and determines the average daily dose ADD, the carcinogenic risks CR and the non-carcinogenic risk hazard quotient HQ which yields the hazard indices HI. The general trend of mean trace metal concentration in the sampled groundwater was in the order of: Zn > Fe > Al > V > Mn > Cu > Cr > Ni > Pb > As > Co > Cd > Sb. All the groundwater risk indices; ADD, CR, HQ and HI were less than 1 in categories of insignificant health risk. The severity of metal toxicity is governed by several factors, such as dose, nutrition, age, and even life style. Therefore, this low trend might not guarantee the complete absence of human health risk. Generally, from risk assessment on trace metals using risk indices, the analyzed water samples might not be at an alarming health risk. However, due to an increasing level of environmental pollution that might be imposed by increasing human activity in this region, water sources might become a potential sink of contaminants; this is significant reason that makes constant monitoring, implementation and treatment of groundwater for drinking purposes obligatory.
S. T. COLERIDGE AND GERMAN TRANSCENDENTAL PHILOSOPHY: INFLUENCE OR CONFLUENCE?
Charles Ngiewih TEKE
Academic Research International , 2012,
Abstract: The article grapples with the complex networking between exponents of German Romantic Idealism and S T Coleridge's metaphysics and transcendental speculations, paying specific attention to Biographia Literaria. It argues that Coleridge was immensely influenced by anddistinguished himself from German philosophers like Immanuel Kant, Johann Gottlieb Fichte, Friedrich Wilhelm Joseph Schelling, Karl Wilhelm Schlegel, Friedrich Leopold, Freiherr von Hardenburg (Novalis) and Georg Wilhelm Friedrich Hegel. These philosphers advancedcomplex, enigmatic and controversial positions on hermeneutic and phenomenological questions of asethetics and sublime, being, nature and mind and spirit, body and soul, the subjective and objevtive and plenitude. The question of influence and/or confluence situatesColeridge's Romantic and idealist speculations in the context of acknowledging the German idealists and submitting to shared ideologies, but at the same time accentuating his formulatedopinions prior to and after he met with or read their works. Biographia Literaria as a seminal treatise on English Romanticism expresses how this networking grounded Coleridge's metaphyics in line with artistic and aesthetic concerns. In other words, Coleridge's conviction that a poet was an ardent expression of the mutual inclusivity between phliosophy and creative writing lends credence to his rigorous critical broodings on continental philosophers. Histheorisation of imagination in philosophical and poetic expression owes much to both these influneces and his personal stance.
Extramurale Praktika im Rahmen des veterin rmedizinischen Studiums [Clinical externships within undergraduate studies in veterinary medicine ]
B?rchers, Mirja,Teke, Alper,Tipold, Andrea
GMS Zeitschrift für Medizinische Ausbildung , 2010, DOI: 10.3205/zma000711
Abstract: [english] The purpose of this study was to evaluate the benefits of checklists for clinical practical courses. Clinical externships are a component of the practical part of the veterinary medicine curriculum. The control is under the responsibility of the training centres. Guidelines and checklists for extramural clinical courses were developed in order to facilitate control mechanisms. The analysis of such checklists should give an overview over the actual situation to enable the setting of minimum standards for extramural courses. The guidelines list practical activities carried out by the students in the veterinary practices or clinics. Data of 360 checklists were assessed in this study to evaluate whether checklists constitute a useful tool to control extramural studies.The results show that checklists are useful to enhance the knowledge of the training centre about the training of students to be adapted. However, the advantage is not completely clear to students. The communication of the importance of the extramural training sessions has to be enhanced. [german] In der vorliegenden Studie soll der Nutzen von Checklisten für klinische Praktika überprüft werden. Im veterin rmedizinischen Studium sind im praktischen Studienteil extramurale klinische Praktika vorgesehen. Die Kontrolle obliegt dabei den Ausbildungsst tten. Um diese Kontrolle übersichtlich zu gestalten, wurden ein Leitfaden und Checklisten für klinische Praktika entwickelt. Die Auswertung soll das Erlangen einer übersicht über die derzeitige Situation und die Schaffung von Mindeststandards bei der Praktikumsgestaltung gew hrleisten. In den Leitf den werden ausgeführte T tigkeiten der Studierenden in den externen kurativen Praxen oder Tierkliniken aufgeführt. Im Rahmen dieser Arbeit wurden die Daten von insgesamt 360 Checklisten erhoben. Die Auswertung soll darüber Aufschluss geben, ob die Einführung von Checklisten eine sinnvolle Erg nzung für die Lehre darstellt. Die Ergebnisse verdeutlichen, dass mit Checklisten ein enormer Erkenntnisgewinn für die Hochschule zu erreichen ist, dieses Potential in der praktischen Anwendung jedoch h ufig nicht vollst ndig ausgesch pft wird und somit die Vermittlung ihrer Wichtigkeit zunehmende Bedeutung erlangt.
Vasospastic angina mimicking inferior myocardial infarction due to high dose cyclophosphamide for bone marrow transplantation conditioning
Hava Uskudar Teke,Alparslan Birdane,Zafer Gulbas
Anadolu Kardiyoloji Dergisi , 2008,
Abstract:
THE EVALUATION OF THE APPROPRIATENESS OF BED USE IN DEPARTMENT OF GENERAL PEDIATRICS IN GüLHANE MILITARY MEDICAL ACADEMY TRAINNING HOSPITAL
Abdulkadir TEKE,Cesim DEM?R,Mustafa ?ZER,Muharrem U?AR
TAF Preventive Medicine Bulletin , 2005,
Abstract: The purpose of the article is to evaluate the appropriateness of bed use in Department of Pediatrics in Gülhane Military Medical Academy, in Ankara, Turkey. The records of 175 patients, were selected randomly out of 525 patients hospitalized in the period between January 01-March 31 2001. The hospital files of these patients were retrospectively reviewed and evaluated according to the Pediatric Appropriateness Evaluation Protocol (PAEP) which have criteria specific to children for admissions and days of stay. A total of 175 patient admission and 909 patient days were evaluated. It was determined that medically appropriate admission rate was 98.3 %and appropriate patient day rate was 88.7%. The influence of factors which can affect the appropriateness of bed use such as the age and gender of the patients, the region where the patients live, and the admission route to the hospital was investigated. While the children older than 2, and the patients from outside Ankara had higher inappropriate rate of patient days, the children admitted through the emergency service had less inappropriate rate of patient days. The factors affecting hospital bed use should be clarified and the reasons for inappropriate bed use in hospitals should be identified in order to improve the health care systems. The researchs to identify the extent of inappropriate bed use should be encouraged to draw policy conclusions to reduce the inappropriate bed use.
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