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Search Results: 1 - 10 of 19187 matches for " Ricardo Drut "
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The Children’s Faecal Matter Structure Is Built by Their Parents  [PDF]
Eduard Cueto Rua, Ricardo Wright, Cecilia Zubiri, Luciana Guzmán, Claudia Losada, M. Inés Urrutia, María T. Gonzalez, Ricardo Drut, Mariela Espósito, Norberto Recalde, Jorge Fiad, Ignacio Go?i, Natalia Belén, María Cristina Arregui
Open Journal of Epidemiology (OJEpi) , 2019, DOI: 10.4236/ojepi.2019.91006
Abstract: Introduction: Humans have gone through physical changes over the last 4 million years. The mouth, however, has not changed teeth quantity or quality. Eight incisors for fruits, vegetables and tubers; four little canines for little animals; eight premolars and twelve flat molars are used for crushing these foods, especially whole grains and legumes. The teeth crushing foods are the first step in the building of faecal matter. Foods are selected mostly according to cultural guidelines than to biological needs. The patterns of consumption are induced by the publicity of industrialized or processed foods. Material and Methods: This study design was observational, analytical, correlational, transversal and prospective. One thousand children (0 - 12 years old) were questioned in order to learn about the relationship between Weekly Eating Frequency (WEF) and Faecal Matter (FM) characteristics. The FM was classified as soft, normal or hard and the outcome was expressed as Dry Faecal Residue (DFR). The WEF and Weekly Bowel Movement Frequency (WBMF) were determined and tabulated according to times per week. Environmental factors, parents’ education level and children’s birth order were examined. Results: There was a strong association between DFR, WBMF and WEF. Environment and education level did not play a key role although birth order did matter. Conclusions: Fibre-free foods (dairies, meats, flours and sweeties or sodas) increased DFR. Foods containing fibre from vegetables decreased DFR, which in turn contributed to the WBMF. Lowest DFR was observed in children under Exclusive Breastfeeding (EB). Distant last-born children had higher DFR. Comments: Daily examples support these results and it is clear that children’s FM is built by their parents. We encourage parents to follow the “mouth nature” rather than the “advertisements nature”.
Celiaquía, una enfermedad paradigmática
Cueto Rua,Eduardo A; Guzmán,Luciana; Nanfito,Gabriela; Barrera,Soledad; Drut,Ricardo;
Archivos argentinos de pediatr?-a , 2008,
Abstract: we are reporting ten recently diagnosed children with celiac disease who presented neither undernutrition nor symptoms suggesting malabsortion syndrome. all showed iga, ema and just eight ttg2 autoantibodies. biopsies allowing histopathologic diagnosis were taken after detailed endoscopic examina- tion from proximal duodenum. samples from distal duodenum were within normal histologic range. the findings are particularly interesting in order to explain cases with aparent disagreements between clinical, laboratory and histopathologic data.
Decay-Accelerating Factor 1 Deficiency Exacerbates Leptospiral-Induced Murine Chronic Nephritis and Renal Fibrosis
María F. Ferrer, Emilia Scharrig, Lucrecia Alberdi, Maia Cedola, Gabriela Pretre, Ricardo Drut, Wen-Chao Song, Ricardo M. Gomez
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0102860
Abstract: Leptospirosis is a global zoonosis caused by pathogenic Leptospira, which can colonize the proximal renal tubules and persist for long periods in the kidneys of infected hosts. Here, we characterized the infection of C57BL/6J wild-type and Daf1?/? mice, which have an enhanced host response, with a virulent Leptospira interrogans strain at 14 days post-infection, its persistence in the kidney, and its link to kidney fibrosis at 90 days post-infection. We found that Leptospira interrogans can induce acute moderate nephritis in wild-type mice and is able to persist in some animals, inducing fibrosis in the absence of mortality. In contrast, Daf1?/? mice showed acute mortality, with a higher bacterial burden. At the chronic stage, Daf1?/? mice showed greater inflammation and fibrosis than at 14 days post-infection and higher levels at all times than the wild-type counterpart. Compared with uninfected mice, infected wild-type mice showed higher levels of IL-4, IL-10 and IL-13, with similar levels of α-smooth muscle actin, galectin-3, TGF-β1, IL-17, IFN-γ, and lower IL-12 levels at 90 days post-infection. In contrast, fibrosis in Daf1?/? mice was accompanied by high expression of α-smooth muscle actin, galectin-3, IL-10, IL-13, and IFN-γ, similar levels of TGF-β1, IL-12, and IL-17 and lower IL-4 levels. This study demonstrates the link between Leptospira-induced murine chronic nephritis with renal fibrosis and shows a protective role of Daf1.
Neutrophil Extracellular Traps are Involved in the Innate Immune Response to Infection with Leptospira
Emilia Scharrig?,Agostina Carestia?,María F. Ferrer?,Maia Cédola?,Gabriela Pretre?,Ricardo Drut,Mathieu Picardeau?,Mirta Schattner?,Ricardo M. Gómez
PLOS Neglected Tropical Diseases , 2015, DOI: 10.1371/journal.pntd.0003927
Abstract: NETosis is a process by which neutrophils extrude their DNA together with bactericidal proteins that trap and/or kill pathogens. In the present study, we evaluated the ability of Leptospira spp. to induce NETosis using human ex vivo and murine in vivo models. Microscopy and fluorometric studies showed that incubation of human neutrophils with Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130 (LIC) resulted in the release of DNA extracellular traps (NETs). The bacteria number, pathogenicity and viability were relevant factors for induction of NETs, but bacteria motility was not. Entrapment of LIC in the NETs resulted in LIC death; however, pathogenic but not saprophytic Leptospira sp. exerted nuclease activity and degraded DNA. Mice infected with LIC showed circulating NETs after 2 days post-infection (dpi). Depletion of neutrophils with mAb1A8 significantly reduced the amount of intravascular NETs in LIC-infected mice, increasing bacteremia at 3 dpi. Although there was a low bacterial burden, scarce neutrophils and an absence of inflammation in the early stages of infection in the kidney and liver, at the beginning of the leptospiruric phase, the bacterial burden was significantly higher in kidneys of neutrophil-depleted-mice compared to non-depleted and infected mice. Surprisingly, interstitial nephritis was of similar intensity in both groups of infected mice. Taken together, these data suggest that LIC triggers NETs, and that the intravascular formation of these DNA traps appears to be critical not only to prevent early leptospiral dissemination but also to preclude further bacterial burden.
Associated or Concomitant Diseases Influence Significantly the Health-Sickness Concept in Celiacs  [PDF]
Eduardo Cueto Rúa, Maria Teresita Gonzalez Villar, Ricardo Wright, Claudia Losada Gómez, Karol Martínez, María Arregui, Luciana Guzmán, Cecilia Zubiri, Viviana Bernedo, Anabella Zosi, Lorena Menéndez, Lucas Ruiz, Leopoldo Mancinelli, María Urrutia, Ricardo Drut
Open Journal of Epidemiology (OJEpi) , 2017, DOI: 10.4236/ojepi.2017.72013
Abstract: It is well-known that feeling to be a healthy or sick person most probably results from the mind than from the body. We all know healthy people who feel sick and vice versa. We were interested in the health and sickness feeling of celiac people, their autorating of these feelings and its conditioning factors as well as their expectations. In this paper we present the results of an inquiry to evaluate these situations. We performed a descriptive, transversal and prospective study for 2 years to groups of celiacs and their families. They received a closed inquiry to be completed before the beginning of the talk. The inquiry included personal data and the co-existence of associated or concomitant (AoC) diseases. Most of the sample’s patients felt to be a healthy person (86.8%). Mothers see their children as healthy and the auto rated criteria is significantly better than the adult celiac person (“t”= -6.024 (p = 0.000)). AoC diseases influenced negatively in the feeling of being healthy and strongly decreased the autorating. Longer time passed on treatment reflects an increase feeling of health and of the autorating. In people with AoC diseases and who feel sick, the increased time of treatment did not show significant differences. People with “gluten sensitivity” felt sicker and auto rated themselves with a lower number than celiacs. Many pediatric gastroenterologists notice that the newly agreed definition of celiac disease, referring it as “autoimmune, chronic, incurable, and multisystemic”, results in a very negative character of the condition which might compromise the future labour of this people as well as their admittance to different health insurance systems.
Sobre la percepción y la decisión políticas de aplicar el asilo diplomático: Una reflexión desde experiencias latinoamericanas
Silvia DRUTéNIT
América Latina Hoy , 2009,
Abstract: RESUMEN: A lo largo de los a os se cuentan por miles los latinoamericanos que recurrieron al asilo como forma de protegerse de la persecución gubernamental. El asilo es un instrumento del derecho interamericano, ratificado como tal por varios estados, para salvaguardar vidas humanas, es decir la de los perseguidos políticos bajo distintos regímenes. La regulación de este instrumento ha sido asunto recurrente de debate y de modificación. En este artículo se presentan hipótesis que problematizan los alcances de la regulación del asilo diplomático y se presentan ciertas claves a partir de condicionantes externas, especialmente en lo que se define como la percepción y la decisión políticas de los diplomáticos. Para ello se rastrean dos experiencias de los a os setenta ocurridas en Argentina y Chile desde un escenario común: las embajadas mexicanas y la disposición estatal de proteger a los perseguidos políticos. . ABSTRACT: Historically, thousands of Latin Americans have sought political asylum to shield theniselves from government's persecution. Many States in the region have ratilied it as a legitimate instrument of Interanserican Law, useful to protect the lives of people being persecuted by their governments due to their political stance. The regulation of this instrument has experienced various modifications, and has been the subject of a recurrent debate. This papen puts forward alternative hypotheses to explain the scope of the regulation of political asylum, and introduces certain codes to understand it based on externa' conditions, in particular, concerning foreign diplornat's perceptions and political decisions. To do so, we examine two cases that took place in the 1970s in rgentina and Chile from a common perspectiva: that of Mexican embassies and the States willingness to protect people subject to political persecution.
Improved lattice operators for non-relativistic fermions
Joaquín E. Drut
Physics , 2012, DOI: 10.1103/PhysRevA.86.013604
Abstract: In this work I apply a recently proposed improvement procedure, originally conceived to reduce finite lattice spacing effects in transfer matrices for dilute Fermi systems, to tuning operators for the calculation of observables. I construct, in particular, highly improved representations for the energy and the contact, as a first step in an improvement program for finite-temperature calculations. I illustrate the effects of improvement on those quantities with a ground-state lattice calculation at unitarity.
Thermodynamics of a Trapped Unitary Fermi Gas
Aurel Bulgac,Joaquin E. Drut,Piotr Magierski
Physics , 2007, DOI: 10.1103/PhysRevLett.99.120401
Abstract: We present the first model-independent comparison of recent measurements of the entropy and of the critical temperature of a unitary Fermi gas, performed by Luo et al., with the most complete results currently available from finite temperature Monte Carlo calculations. The measurement of the critical temperature in a cold fermionic atomic cloud is consistent with a value $T_c=0.23(2)epsilon_F$ in the bulk, as predicted by the present authors in their Monte Carlo calculations.
Renormalization group flow of quartic perturbations in graphene: Strong coupling and large-N limits
Joaquin E. Drut,Dam Thanh Son
Physics , 2007, DOI: 10.1103/PhysRevB.77.075115
Abstract: We explore the renormalization group flow of quartic perturbations in the low-energy theory of graphene, in the strong Coulomb coupling and large-N limits, where N is the number of fermion flavors. We compute the anomalous dimensions of the quartic couplings u up to next-to-leading order in 1/N and find both relevant and irrelevant directions in the space of quartic couplings. We discuss possible phase diagrams and relevance for the physics of graphene.
Quantum Monte Carlo Simulations of the BCS-BEC Crossover at Finite Temperature
Aurel Bulgac,Joaquin E. Drut,Piotr Magierski
Physics , 2008, DOI: 10.1103/PhysRevA.78.023625
Abstract: The Quantum Monte Carlo method for spin 1/2 fermions at finite temperature is formulated for dilute systems with an s-wave interaction. The motivation and the formalism are discussed along with descriptions of the algorithm and various numerical issues. We report on results for the energy, entropy and chemical potential as a function of temperature. We give upper bounds on the critical temperature T_c for the onset of superfluidity, obtained by studying the finite size scaling of the condensate fraction. All of these quantities were computed for couplings around the unitary regime in the range -0.5 \le (k_F a)^{-1} \le 0.2, where a is the s-wave scattering length and k_F is the Fermi momentum of a non-interacting gas at the same density. In all cases our data is consistent with normal Fermi gas behavior above a characteristic temperature T_0 > T_c, which depends on the coupling and is obtained by studying the deviation of the caloric curve from that of a free Fermi gas. For T_c < T < T_0 we find deviations from normal Fermi gas behavior that can be attributed to pairing effects. Low temperature results for the energy and the pairing gap are shown and compared with Green Function Monte Carlo results by other groups.
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