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Search Results: 1 - 10 of 168072 matches for " Renee E. Doll "
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A Comparison of Blind and Laryngoscopic Insertion of the EasyTube  [PDF]
Julia C. Caldwell, David P. De Korte, Renee E. Doll, Sonia J. Vaida
Open Journal of Anesthesiology (OJAnes) , 2015, DOI: 10.4236/ojanes.2015.58035
Abstract: Introduction: The EasyTube is a disposable, polyvinyl-chloride, double-lumen, supraglottic airway device, which allows ventilation in either esophageal or tracheal position. The EasyTube may be positioned into the esophagus blindly or using a laryngoscope. Methods: Our study compared blind versus laryngoscopic-guided esophageal EasyTube insertion. Thirty two anesthesiologists inserted an EasyTube, size 41 Fr, into a mannequin, by using a blind and a laryngoscopic technique in a 2 × 2 crossover design. Results: No statistically significant difference in the time to achieve an effective airway was found: 23.9 ± 6 seconds for the blind and 29.5 ± 7.6 seconds for the laryngoscopic-guided technique. Conclusion: EasyTube insertion was equally successful with or without a laryn-goscope in a mannequin when used by anesthesia providers.
Accounting as an Instrument of Social Justice  [PDF]
Theresa F. Henry, Athar Murtuza, Renee E. Weiss
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.31009
Abstract: This article builds upon calls for a shift in the paradigm of the accounting discipline, away from preparing or certifying financial reporting of management activities aimed at maximizing share-holder wealth toward recognition that businesses must also be accountable to other stakeholders and indeed the community at large. If individuals in business apply a sound moral compass to their activities and decisions, we believe that commerce can shift toward outcomes that may not only satisfy shareholders but also contribute to the common good. In this article, we are concerned with the role of accounting and business education. We enumerate recommendations toward achieving this paradigm shift from profit maximization to social justice. In some cases, the instructor may implement changes in their pedagogy at their discretion, while in other cases the change may require approval at the department or at higher levels of the university administration. We begin with a discussion of recent accounting and financial reporting failures as well as the global financial crisis. The dangers created by risky practices of financial institutions “too big to fail” and the systemic risk of a global marketplace have not been resolved. We articulate the need for ethics in the accounting and business curricula, a need that is hardly satisfied by the one course typically offered by universities at the graduate level. We propose that businesses and the accounting profession can realize change by redefining accounting as an instrument of accountability. To accomplish this change, each university must critically examine its curricula and reflect topics and material most important to ethical and moral behavior, including borrowing from the liberal arts disciplines. Finally, this article shows how an interfaith approach grounded in social justice to infuse ethical and moral behavior within the accounting curriculum can work.
No Association Between Variant N-acetyltransferase Genes, Cigarette Smoking and Prostate Cancer Susceptibility Among Men of African Descent
La Creis Renee Kidd,Tiva T. VanCleave,Mark A. Doll,Daya S. Srivastava
Biomarkers in Cancer , 2011,
Do residents of food deserts express different food buying preferences compared to residents of food oases? A mixed-methods analysis
Renee E Walker, Jason Block, Ichiro Kawachi
International Journal of Behavioral Nutrition and Physical Activity , 2012, DOI: 10.1186/1479-5868-9-41
Abstract: We used the mixed-methods approach of concept mapping, which allows participants to identify, list, and organize their perceptions according to importance. Resulting maps visually illustrate priority areas.Sixty-seven low-income adults completed the concept mapping process that identified 163 unique statements (e.g. relating to affordability, taste, and convenience) that influence food buying practices. Multivariate statistical techniques grouped the 163 statements into 8 clusters or concepts. Results showed that average cluster ratings and rankings were similar between residents of food deserts and food oases.The implication of this study pertains to the importance of community resources and emergency food assistance programs that have served to minimize the burden associated with hunger and poor food access among low-income, urban populations.
Comparative Monte Carlo Efficiency by Monte Carlo Analysis
B. M. Rubenstein,J. E. Gubernatis,J. D. Doll
Physics , 2010, DOI: 10.1103/PhysRevE.82.036701
Abstract: We propose a modified power method for computing the subdominant eigenvalue $\lambda_2$ of a matrix or continuous operator. Here we focus on defining simple Monte Carlo methods for its application. The methods presented use random walkers of mixed signs to represent the subdominant eigenfuction. Accordingly, the methods must cancel these signs properly in order to sample this eigenfunction faithfully. We present a simple procedure to solve this sign problem and then test our Monte Carlo methods by computing the $\lambda_2$ of various Markov chain transition matrices. We first computed ${\lambda_2}$ for several one and two dimensional Ising models, which have a discrete phase space, and compared the relative efficiencies of the Metropolis and heat-bath algorithms as a function of temperature and applied magnetic field. Next, we computed $\lambda_2$ for a model of an interacting gas trapped by a harmonic potential, which has a mutidimensional continuous phase space, and studied the efficiency of the Metropolis algorithm as a function of temperature and the maximum allowable step size $\Delta$. Based on the $\lambda_2$ criterion, we found for the Ising models that small lattices appear to give an adequate picture of comparative efficiency and that the heat-bath algorithm is more efficient than the Metropolis algorithm only at low temperatures where both algorithms are inefficient. For the harmonic trap problem, we found that the traditional rule-of-thumb of adjusting $\Delta$ so the Metropolis acceptance rate is around 50% range is often sub-optimal. In general, as a function of temperature or $\Delta$, $\lambda_2$ for this model displayed trends defining optimal efficiency that the acceptance ratio does not. The cases studied also suggested that Monte Carlo simulations for a continuum model are likely more efficient than those for a discretized version of the model.
The Construction of Double-Ended Classical Trajectories
A. E. Cho,J. D. Doll,D. L. Freeman
Physics , 1994, DOI: 10.1016/0009-2614(94)01058-7
Abstract: In the present paper we describe relaxation methods for constructing double-ended classical trajectories. We illustrate our approach with an application to a model anharmonic system, the Henon-Heiles problem. Trajectories for this model exhibit a number of interesting energy-time relationships that appear to be of general use in characterizing the dynamics.
No Association Between Variant N-acetyltransferase Genes, Cigarette Smoking and Prostate Cancer Susceptibility Among Men of African Descent
La Creis Renee Kidd, Tiva T. VanCleave, Mark A. Doll, Daya S. Srivastava, Brandon Thacker, Oyeyemi Komolafe, Vasyl Pihur, Guy N. Brock and David W. Hein
Biomarkers in Cancer , 2012, DOI: 10.4137/BIC.S6111
Abstract: Objective: We evaluated the individual and combination effects of NAT1, NAT2 and tobacco smoking in a case-control study of 219 incident prostate cancer (PCa) cases and 555 disease-free men. Methods: Allelic discriminations for 15 NAT1 and NAT2 loci were detected in germ-line DNA samples using Taqman polymerase chain reaction (PCR) assays. Single gene, gene-gene and gene-smoking interactions were analyzed using logistic regression models and multi-factor dimensionality reduction (MDR) adjusted for age and subpopulation stratification. MDR involves a rigorous algorithm that has ample statistical power to assess and visualize gene-gene and gene-environment interactions using relatively small samples sizes (i.e., 200 cases and 200 controls). Results: Despite the relatively high prevalence of NAT1*10/*10 (40.1%), NAT2 slow (30.6%), and NAT2 very slow acetylator genotypes (10.1%) among our study participants, these putative risk factors did not individually or jointly increase PCa risk among all subjects or a subset analysis restricted to tobacco smokers. Conclusion: Our data do not support the use of N-acetyltransferase genetic susceptibilities as PCa risk factors among men of African descent; however, subsequent studies in larger sample populations are needed to confirm this finding.
Heterogeneous Sensory Innervation and Extensive Intrabulbar Connections of Olfactory Necklace Glomeruli
Renee E. Cockerham, Adam C. Puche, Steven D. Munger
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0004657
Abstract: The mammalian nose employs several olfactory subsystems to recognize and transduce diverse chemosensory stimuli. These subsystems differ in their anatomical position within the nasal cavity, their targets in the olfactory forebrain, and the transduction mechanisms they employ. Here we report that they can also differ in the strategies they use for stimulus coding. Necklace glomeruli are the sole main olfactory bulb (MOB) targets of an olfactory sensory neuron (OSN) subpopulation distinguished by its expression of the receptor guanylyl cyclase GC-D and the phosphodiesterase PDE2, and by its chemosensitivity to the natriuretic peptides uroguanylin and guanylin and the gas CO2. In stark contrast to the homogeneous sensory innervation of canonical MOB glomeruli from OSNs expressing the same odorant receptor (OR), we find that each necklace glomerulus of the mouse receives heterogeneous innervation from at least two distinct sensory neuron populations: one expressing GC-D and PDE2, the other expressing olfactory marker protein. In the main olfactory system it is thought that odor identity is encoded by a combinatorial strategy and represented in the MOB by a pattern of glomerular activation. This combinatorial coding scheme requires functionally homogeneous sensory inputs to individual glomeruli by OSNs expressing the same OR and displaying uniform stimulus selectivity; thus, activity in each glomerulus reflects the stimulation of a single OSN type. The heterogeneous sensory innervation of individual necklace glomeruli by multiple, functionally distinct, OSN subtypes precludes a similar combinatorial coding strategy in this olfactory subsystem.
Afferent activity to necklace glomeruli is dependent on external stimuli
Renee E Cockerham, Frank L Margolis, Steven D Munger
BMC Research Notes , 2009, DOI: 10.1186/1756-0500-2-31
Abstract: To determine whether the principal source of chemostimuli for GC-D+ neurons is external or internal to the nose, we assessed the consequences of removing external chemostimuli for afferent activity to the necklace glomeruli. To do so, we performed unilateral naris occlusions in Gucy2d-Mapt-lacZ +/- mice [which express a β-galactosidase (β-gal) reporter specifically in GC-D+ neurons] followed by immunohistochemistry for β-gal and a glomerular marker of afferent activity, tyrosine hydroxylase (TH). We observed a dramatic decrease in TH immunostaining, consistent with reduced or absent afferent activity, in both necklace and non-necklace glomeruli ipsilateral to the occluded naris.Like other MOB glomeruli, necklace glomeruli exhibit a large decrease in afferent activity upon removal of external stimuli. Thus, we conclude that activity in GC-D+ neurons, which specifically innervate necklace glomeruli, is not dependent on internal stimuli. Instead, GC-D+ neurons, like other OSNs in the MOE, primarily sense the external world.The mammalian olfactory system responds to a multitude of chemical stimuli, including general odors that convey information about food, prey and predators, and semiochemicals such as pheromones and social cues that can influence stereotypical behaviors and hormonal states [1,2]. To accomplish this massive task, mammals employ a number of distinct olfactory subsystems, each of which may be tuned to particular subsets of olfactory stimuli [1]. For example, subpopulations of sensory neurons in the vomeronasal organ that express V2R-type receptors are responsive to MHC peptides [3], peptides found in glandular secretions [4], or lipocalin proteins present in urine (i.e., major urinary proteins or MUPs) [5]. Sensory neurons in the main olfactory epithelium (MOE) that respond to the natriuretic peptides uroguanylin and guanylin [6] and to the gas CO2 [7] can be distinguished from other cells by their specific expression of the guanylyl cyclase GC-D, the ph
Mutagenesis of RpoE-like sigma factor genes in Bdellovibrio reveals differential control of groEL and two groES genes
Carey Lambert, Rob Till, Laura Hobley, Renee E. Sockett
BMC Microbiology , 2012, DOI: 10.1186/1471-2180-12-99
Abstract: We find that one sigma factor gene, bd3314, cannot be deleted from Bdellovibrio in either predatory or prey-independent growth states, and is therefore possibly essential, likely being an alternate sigma 70. Deletion of one of two Group IV-like sigma factor genes, bd0881, affects flagellar gene regulation and results in less efficient predation, although not due to motility changes; deletion of the second, bd0743, showed that it normally represses chaperone gene expression and intriguingly we find an alternative groES gene is expressed at timepoints in the predatory cycle where intensive protein synthesis at Bdellovibrio septation, prior to prey lysis, will be occurring.We have taken the first step in understanding how alternate sigma factors regulate different processes in the predatory lifecycle of Bdellovibrio and discovered that alternate chaperones regulated by one of them are expressed at different stages of the lifecycle.
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