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Search Results: 1 - 10 of 413176 matches for " Renan U. M.;Antonangelo "
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Experimental pleurodesis induced by antibiotics (macrolides or quinolones)
Teixeira, Lisete R.;Vargas, Francisco S.;Acencio, Milena M. P.;Bumlai, Renan U. M.;Antonangelo, Leila;Marchi, Evaldo;
Clinics , 2006, DOI: 10.1590/S1807-59322006000600012
Abstract: purpose: chemical pleurodesis is a therapeutic tool for the treatment of recurrent pleural effusions, mainly those of neoplastic etiology. in the past, tetracycline was the sclerosant agent of choice in clinical practice, but presently, there is no consensus about an ideal agent. the aim of this study was to evaluate the effectiveness of macrolides (azithromycin and clarithromycin) or quinolones (levofloxacin and gatifloxacin) in inducing experimental pleurodesis in rabbits. method: forty new zealand rabbits randomized into groups of 10 received (at a total volume of 2 ml for each animal) 1 of the 4 drugs by intrapleural injection. after 28 days, the animals were euthanized and the pleural cavity was evaluated macroscopically and microscopically. results: the intensity of the macroscopic adhesions was mild in all groups. on microscopic analysis, minimal pleural fibrosis and inflammation were observed in all animals. conclusion: the macrolides (azithromycin or clarithromycin) and the quinolones (levofloxacin or gatifloxacin) when injected into the normal pleural space of rabbits are not effective in promoting pleurodesis. additional research is required to identify sclerosing agents capable of inducing pleurodesis.
O papel da plausibilidade na avalia??o da pesquisa científica
Almeida,Renan M V R;
Revista de Saúde Pública , 2011, DOI: 10.1590/S0034-89102011000300021
Abstract: the paper discusses the impact of plausibility (the a priori probability) on the results of scientific research, according to the approach proposed by ioannidis, concerning the percentage of null hypotheses erroneously classified as "positive" (statistically significant). the question "what fraction of positive results are true-positives?", which is equivalent to the positive predictive value, is dependent on the combination of true and false hypotheses within a given area. for example, consider an area in which 90% of hypotheses are false and α = 0.05 and power = 0.8: for every 1,000 hypotheses, 45 (900 x 0.05) are false-positives and 80 (100 x 0.8) are true-positives. therefore, the probability of a positive result being a false-positive is 45/125. in addition, the reporting of negative results as if they were positive would contribute towards an increase in this fraction. although this analysis is difficult to quantify, and these results are likely be overestimated, it has two implications: i) plausibility should be considered in the analysis of the ethical adequacy of a research proposal, and ii) mechanisms aimed at registering studies and protocols should be encouraged.
Drainage Bed: A Natural System for WTP Sludge Dewatering and Drying with Different Coagulant Chemicals in Tropical Countries  [PDF]
Marcelo M. Barroso, Cali L. Achon, Renan F. Reis, Jo?o S. Cordeiro
Journal of Water Resource and Protection (JWARP) , 2014, DOI: 10.4236/jwarp.2014.611097

This study seeks to evaluate the mechanisms for dewatering sludge from Water Treatment Plants (WTP) in a natural system that uses nonwoven polyester geotextile blankets named Drainage Bed (DB). Dewatering mechanisms are divided into two stages: Drainage and Drying Phases. For the Drainage Phase, the results showed that the solids content of the Aluminum Sulfate sludge reached 8.9% to 18.3% and the PACl sludge 1.8% to 6.5%, the volume reduction on this phase exceeding 50% and 74%, respectively. The final solids content, after the Drying Phase, was greater than 28%, reaching 90%. In the Drainage Phase the lower the Surface Application Rate—SAR [kg/m2] is, the greater the drainage flow will be. In the Drying Phase, moisture and insolation were key factors in drying sludge. Thus, the Drying Phase in the DB takes special attention for being virtually nonexistent in dewatering technologies in a closed system (confined) without exposure to solar energy. The use of the DB as a natural system for dewatering WTP sludge in tropical countries proved to be a promising alternative, because of its efficient removal of water from sludge coupled with operational simplicity and low costs, provided there is area available.

The usefulness of adenosine deaminase in the diagnosis of tuberculous pericarditis
Tuon, Felipe Francisco;Silva, Vivian Iida da;Almeida, Gisele M. Duboc de;Antonangelo, Leila;Ho, Yeh Li;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2007, DOI: 10.1590/S0036-46652007000300006
Abstract: the objective of this study was to evaluate the adenosine deaminase (ada) activity usefulness in the diagnosis of tuberculous pericarditis (tp), comparing its value with pericardial effusions (pe) caused by other pericardial diseases. a retrospective case-control study was conducted with nine cases of tp and 39 other than tp diseases (12 neoplastic, 11 septic and 16 unknown origin). every patient included in this study had pe samples submitted to ada activity measures and microbiological analysis, and then had pericardial tissue samples submitted to microbiological and histopathological examination. considering the value of 40 u/l as the cut-off for the diagnosis of tp, the specificity and sensitivity were respectively of 72% and 89%. the specificity of ada activity for the tp was best applied in the differential diagnosis from pe of unknown origin. the present study demonstrates the clinical value of the measurement of ada activity in pe in the diagnosis of tp.
Coleta e preserva??o do líquido pleural e biópsia pleural
Antonangelo, Leila;Capelozzi, Vera Luiza;
Jornal Brasileiro de Pneumologia , 2006, DOI: 10.1590/S1806-37132006000900001
Abstract: the samples of pleural fluid obtained by thoracentesis for the diagnosis of transudates and exudates shall follow a routine of collection and preservation for an appropriate laboratorial analysis. equally, fragments of pleura biopsy obtained for the differential diagnosis of the exudates should be collected in a systematic way in order to optimize the diagnosis and facilitate the institution of appropriate therapeutics actions.
Influência dos níveis séricos de IGF-I e de testosterona sobre o perfil lipídico e glicêmico em homens acromegálicos
Figueiredo, Patrícia R. L.;Martins, Manoel R. A.;Montenegro, Renan M.;Albano, M?nica F.;Montenegro Jr., Renan M.;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2009, DOI: 10.1590/S0004-27302009000800018
Abstract: objectives: to evaluate the influence of igf-i and testosterone on the lipid profile and glycemia in acromegalic men. methods: fifteen acromegalic men were studied. results: the hypogonadic patients presented lower hdl-c and higher tryglicerides, ldl-c, glycemia, gh and igf-i. serum igf-i was inversely correlated with hdl-c (r = - 0.57, p = 0.04) and directly with tg (r = 0.62, p = 0.01) and glycemia (r = 0.66, p = 0.008), whereas serum testosterone correlated directly with hdl-c (r = 0.52, p = 0.05) and inversely with tg (r = - 0.57, p = 0.02), ldl-c (r = - 0.53, p = 0.04) and fasting blood glucose (r = - 0.54, p = 0.03). igf-i and testosterone were inversely correlated (r = - 0.585, p = 0.028). conclusion: these results suggest that the most important intervention in reducing cardiovascular risk in these patients is to control the activity of the disease.
Modelagem matemática e difusividade efetiva das sementes de pinh?o-manso (Jatropha curcas L.) durante a secagem
Resende, Osvaldo;Ullmann, Renan;Siqueira, Valdiney C;Chaves, Tarcísio H;Ferreira, Lênio U;
Engenharia Agrícola , 2011, DOI: 10.1590/S0100-69162011000600010
Abstract: the aim of this study was to adjust different mathematical models to experimental data for jatropha seed drying (jatropha curcas l.) and determine the effective diffusion coefficient and obtain the activation energy for the temperature range used. jatropha seeds harvested with moisture content of 0.67 (decimal d.b.) and dried in a natural environment to reduce and homogenize the moisture content for 0.30 (decimal d.b.). jatropha drying was performed in experimental drier maintained at controlled temperatures of 30; 40; 50; 60 or 70 ± 1 oc and relative humidity of 55.98; 41.44; 35.35; 26.21 and 13.37 ± 3%, respectively. experimental data were fitted to eleven mathematical models used to represent the process of drying of agricultural products. it was concluded that among the models tested, page and henderson and modified pabis presented the best fitting to experimental data, and the page model selected for describing the drying curves from jatropha because of their simplicity; the effective diffusion coefficient increases with increasing temperature, with magnitudes between 3.93x10-10 and 9.19x10-10 m2 s-1 for the temperature range 30-70 oc, respectively. the activation energy for liquid diffusion during jatropha drying was 15.781 kj mol-1.
A new correlation for single and two-phase flow pressure drop in round tubes with twisted-tape inserts
Kanizawa, Fabio T.;Hernandes, Renan S.;Moraes, Anderson A. U. de;Ribatski, Gherhardt;
Journal of the Brazilian Society of Mechanical Sciences and Engineering , 2011, DOI: 10.1590/S1678-58782011000500006
Abstract: twisted-tape inserts are frequently used in heat exchangers as a passive and inexpensive heat transfer enhancement method. however, their use results not only heat transfer coefficient increments, but also pressure drop penalties. the present study analyses the literature on single and two-phase frictional pressure drop inside tubes with twisted-tape inserts focusing on the physical mechanism and the effects of the use of twisted-tape in comparison to plain tubes. experimental data were gathered from the open literature and compared against the available correlations developed in order to predict two-phase frictional pressure drop in tubes containing twisted-tape inserts. it was found that none of the correlations was able to predict such a database accurately. a new correlation to estimate the friction factor for two-phase flows inside tubes with twisted-tape is also proposed. contrarily to previous studies, the proposed correlation presents reasonable predictions under single and two-phase flow conditions and obeys the trends when the twisted-tape ratio tends to zero and infinite.
The Effects of Spatial Scale on Breakdown of Leaves in a Tropical Watershed
Renan S. Rezende, Mauricio M. Petrucio, José F. Gon?alves
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0097072
Abstract: The objective was to assess the effects of natural variation in the physical structure of the environment on biological communities and on the processing of Eucalyptus cloeziana and Inga laurina and to identify the controlling factors at different scales along stream order gradients. The study area consisted of 14 sampling sites distributed within a tropical watershed (1st, 2nd, 3rd and 4th order streams replicated in 4 sub-basins). Our samples consisted of 3 g of leaves of E. cloeziana (high-quality) and I. laurina (low-quality) placed in 252 bags with 10mm mesh (measured by the chemical composition of the detritus). Four samples of each leaf type were collected periodically (three times) over a period of 75–125 days and washed on a sieve to separate the invertebrates. A series of leaf disks were cut to determine ash-free dry mass, polyphenol, lignin, cellulose, total microbial biomass and fungal biomass, and the remaining material was oven-dried to determine the dry weight. We performed analyses within and between spatial scales (regional and local) to assess which watershed scale was the more import determinant of the leaf breakdown rate (k). The microbial and shredder were most influenced at the local scale (stream order). Shredders were influenced by microorganisms, with stronger interactions between them than were found to drive the k at the local scale. Moreover, differences in the overall k and abiotic variables were more strongly influenced at the regional scale (sub-basin), showing that the study scale alters the response of the studied variables. We found higher k values at higher values of water velocity, dissolved oxygen and temperature, all of which accelerate biological metabolism in response to variations on the regional scale. Watersheds with warmer microclimates and streams with higher nutrient levels and oxygen could be accelerating the ecosystem metabolism, independent of the detritus quality.
Quasi-stationary simulations of the directed percolation universality class in d = 3 dimensions
Renan S Sander,Marcelo M de Oliveira,Silvio C Ferreira
Physics , 2011, DOI: 10.1088/1742-5468/2009/08/P08011
Abstract: We present quasi-stationary simulations of three-dimensional models with a single absorbing configuration, namely the contact process (CP), the susceptible-infected-susceptible (SIS) model and the contact replication process (CRP). The moment ratios of the order parameters for the DP class in three dimensions were set up using the well established SIS and CP models. We also show that the mean-field exponent for d = 3 reported previously for the CRP (Ferreira 2005 Phys. Rev. E 71 017104) is a transient observed in the spreading analysis.
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