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Search Results: 1 - 10 of 42668 matches for " Regina;Quírico-Santos "
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Determination of soluble ICAM-1 and TNFalphaR in the cerebrospinal fluid and serum levels in a population of Brazilian patients with relapsing-remitting multiple sclerosis
Alves-Leon, Soniza Vieira;Batista, Elizabeth;Papais-Alvarenga, Regina;Quírico-Santos, Thereza;
Arquivos de Neuro-Psiquiatria , 2001, DOI: 10.1590/S0004-282X2001000100005
Abstract: cytokines and adhesion molecules have been implicated in the pathogenesis of multiple sclerosis (ms), a chronic inflammatory disease of the central nervous system. in this study we analyzed intrathecal (csf) and serum levels of soluble intercellular adhesion molecule (icam-1) and tnfar (60kd) from 20 patients with clinically definite ms during acute relapse or stable disease. comparing to control groups of healthy individuals and patients with intervertebral herniated disc, ms patients showed increased levels (p< 0.001) of sicam-1 and tnfar in both serum and csf samples. regardless stage of disease there was no significant difference in the levels of sicam-1 during acute relapse (657±124.9 ng/ml) or remission (627±36.2 ng/ml). a steady increase of tnfar (60kd) in both serum and csf, indicate the existence of a continuous inflammatory process within the brain tissue of ms patients despite absence of clinical signs of disease activity.
Determination of soluble ICAM-1 and TNFaR in the cerebrospinal fluid and serum levels in a population of Brazilian patients with relapsing-remitting multiple sclerosis
Alves-Leon Soniza Vieira,Batista Elizabeth,Papais-Alvarenga Regina,Quírico-Santos Thereza
Arquivos de Neuro-Psiquiatria , 2001,
Abstract: Cytokines and adhesion molecules have been implicated in the pathogenesis of multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system. In this study we analyzed intrathecal (CSF) and serum levels of soluble intercellular adhesion molecule (ICAM-1) and TNFalphaR (60kD) from 20 patients with clinically definite MS during acute relapse or stable disease. Comparing to control groups of healthy individuals and patients with intervertebral herniated disc, MS patients showed increased levels (p< 0.001) of sICAM-1 and TNFalphaR in both serum and CSF samples. Regardless stage of disease there was no significant difference in the levels of sICAM-1 during acute relapse (657±124.9 ng/ml) or remission (627±36.2 ng/ml). A steady increase of TNFalphaR (60kD) in both serum and CSF, indicate the existence of a continuous inflammatory process within the brain tissue of MS patients despite absence of clinical signs of disease activity.
Determina??o de autoanticorpos para antígenos da mielina no soro de pacientes HLA - DQB1*0602 com esclerose múltipla
Carvalho, Adriana;Sant'anna, Gabriele;Santos, Cláudio Cirne;Frugulhetti, Izabel Palmer;Leon, Soniza Alves;Quírico-Santos, Thereza;
Arquivos de Neuro-Psiquiatria , 2003, DOI: 10.1590/S0004-282X2003000600015
Abstract: multiple sclerosis (ms) is a chronic inflammatory demyelinating disease of the human central nervous system (cns) mediated by autoimmune th1 lymphocytes. we determined the serum levels of autoantibodies for myelin basic protein (mbp), proteolipid (plp) and myelin oligodendrocyte glycoprotein sequence mog 92-106 in a group of 54 healthy individuals and 26 ms patients expressing or not hla dqb1*0602. regardless expression of the susceptibility alelle dqb1*0602, ms patients presented marked (p<0.0001) igg antibody production for mbp and mog92-106. yet, significant (p<0.0001) iga antibody levels were mainly observed for plp and mog antigens. our results suggest that other hla class ii alleles may be conferring susceptibility to ms in this population and influencing the pattern of immune recognition of encephalitogen antigens. furthermore, distinct igg and/or iga autoantibody production may be contributing to the control or maintenance of the cns inflammatory reaction.
As fun??es do Juízo final como imagem religiosa
Quírico, Tamara;
História (S?o Paulo) , 2010, DOI: 10.1590/S0101-90742010000100009
Abstract: the use of images as historical sources has been reason for debate for some decades. the current article aims to defend its importance since they own diverse origin from the written sources, the visual sources allow us to realize other ways of manifestation of the social life, as well new social actors. the text concentrates the analysis in visual repesentations of the topic of the last judgement performed in the middle age, seeking a better understanding not only of the religiousness, but also own history of the societies that created these images. forms of understanding the paintings about the final judgement in the medieval period will be discussed in this article, as well the functions expected for this kind of image. the analysis will be found particularly in the italian examples painted between xii and xiv centuries.
Composition and fatty acid profile of milk from cows on pasture subjected to licuri oil supplement
Lima, Luciano dos Santos;Oliveira, Ronaldo Lopes;Bagaldo, Adriana Regina;Garcez Neto, Américo Fróes;Ribeiro, Cláudio Vaz Di Mambro;Lanna, Dante Pazzanese Duarte;
Revista Brasileira de Zootecnia , 2011, DOI: 10.1590/S1516-35982011001200033
Abstract: the objective of this study was to determine the best level of oil licuri concentrate on dairy cows. the best level was determined through an analysis of the milk's chemical composition and fatty acid profile. sixteen lactating cows from the holstein × zebu cross breed kept on tanzania grass pastures were divided into four 4 × 4 latin squares, which were formed by four experimental periods of 21 days. the 21-day experimental periods were divided into 17 days for adaptation and four days for collection. cows received three kg of concentrate per day, at the time of milking. treatments consisted of four types of feed containing the following levels: 0, 1.5, 3.0, and 4.5% inclusion of dry matter (dm) licuri oil concentrate. the licuri oil levels changed the fatty acids' profile with a linear increase in the short-chain fatty acid and medium and linearly reduced the concentration of lcfa. the highest level of licuri oil was 4.5% of dm concentrate, which changed the composition of milk through an increase in the percentage of fat and total solids. this result is of prominent notice to the dairy industry.
Production performance of lactating dairy cows at pasture fed concentrate supplemented with licuri oil
Lima, Luciano dos Santos;Oliveira, Ronaldo Lopes;Bagaldo, Adriana Regina;Garcez Neto, Américo Fróes;Barbosa, Larissa Pires;Borja, Máikal Souza;
Revista Brasileira de Zootecnia , 2011, DOI: 10.1590/S1516-35982011001200032
Abstract: the objective of this study was to determine the optimal level of licuri oil to use in the concentrate of lactating dairy cows on pasture, through growth performance, feed conversion and cost of the supplementation. a total of 16 dairy cows, holstein × zebu crossbreed, were kept on tanzania grass pasture. cows were divided into four latin squares, 4 × 4, formed by four experimental periods of 21 days, divided into 17 days for adaptation and four days for data collection. cows received three kg of concentrate per day at the time of milking, and the treatments consisted of four diets containing licuri oil at levels of 0.0, 1.5, 3.0, and 4.5% of the concentrated dry matter. there was a linear increase in the daily milk yield, corrected to 3.5% fat, and an improvement in the feed conversion of the dry matter and neutral detergent fiber with the inclusion of the licuri oil. the optimal level of licuri oil was 1.5% of the concentrated dm for dairy cows on pasture, whose level has the best profit sale of milk, with positive results in the corrected daily milk production and conversion of the feed nutrients.
Brucella canis infection in dogs attended in veterinary clinics from patos, Paraíba state, Brazil
Fernandes, Annielle Regina Fonseca;Azevedo, Sérgio Santos de;Piatti, Rosa Maria;Pinheiro, Eliana Scarcelli;Genovez, Margareth élide;Azevedo, Adílio Santos de;Batista, Carolina de Sousa Américo;Alves, Clebert José;
Brazilian Journal of Microbiology , 2011, DOI: 10.1590/S1517-83822011000400023
Abstract: to determine the frequency of anti-brucella canis antibodies in dogs attended in veterinary clinics from patos, paraíba state, brazil, as well as to identify risk factors and to isolate and identify the agent, 193 dogs were used. agar gel immunodiffusion test (agid) was used to detect b. canis antibodies in sera. isolation of b. canis was carried out in blood and bone marrow from seropositive animals. six animals tested seropositive in agid, resulting in a frequency of 3.11%. b. canis was isolated from bone marrow of one seropositive animal, with confirmation by pcr. lack of cleaning of the dog's environment was identified as risk factor (odds ratio = 7.91). this is the first report of isolation of b. canis in dogs from the northeast region of brazil.
Zumbido no trabalhador exposto ao ruído
Weber, Sandra Regina;Périco, Eduardo;
Revista da Sociedade Brasileira de Fonoaudiologia , 2011, DOI: 10.1590/S1516-80342011000400016
Abstract: purpose: to verify the characteristics, prevalence, and repercussion of tinnitus in noise-exposed workers. methods: a total of 585 workers from a food industry were questioned about tinnitus. individuals that reported tinnitus with duration of more than five minutes and for more than six months answered an interview regarding occupational and tinnitus histories, answered to the tinnitus handicap inventory questionnaire, and carried out a pure tone audiometry. data were statistically analyzed. results: tinnitus prevalence was 7.2% (n=42), the average noise exposure time was three years and eight months, and the average tinnitus perception time was three years and seven months. there was a predominance of intermittent (88%) and bilateral (53.4%) perception, with progressive onset (66.7%). a total of 50% didn't present hearing loss. the subjects reported that tinnitus interferes mainly in concentration; stress, silence and noise were the worsening factors most frequently mentioned. there was a difference between noise exposure time and tinnitus perception time in individuals without hearing loss. conclusion: the absence of hearing loss in half the individuals and the correlation between noise exposure time and tinnitus perception time, in these subjects, suggest a possible effect of noise not restrained to the peripheral auditory system, and the need to include tinnitus in hearing conservation programs.
Uma metodologia para análises comparativas da capacidade produtiva entre arames maci?os (MIG/MAG) e tubulares (eletrodo tubular)
Garcia, Regina Paula;Scott, Américo;
Soldagem & Inspe??o , 2011, DOI: 10.1590/S0104-92242011000200007
Abstract: considering the operational differences between the process tubular electrode and gmaw process, two welding processes competitive in terms of quality and productivity, was evaluated a methodology to the productive capacity of each process under different aspects. it was realized a comparative study of melting rate, deposition rate and efficiency deposition, concluding with an analysis of the productive capacity of each wire in question. welds beads were evaluated using the wire e71t-1 and er70s6, under shielding gas 100% co2 and ar +25% co2 at different current levels, using groove plates. for enable a good comparison with the practical reality of each consumable, were tried to work with every combination wire / shielding gas and appropriate conditions of contact-tip-to-workpiece distance and arc voltage (for the current range studied, solid wire was used in short-circuit, using a smaller dbcp). the volume of the weld beads per meter was made the same for each level of current.). in general, the tubular wire used showed a higher deposition rate than solid wire, but with a higher consumption of material to form the same weld bead. an economic analysis showed that with the tubular wire is possible to perform a bead in less time (higher productivity), and the higher cost may be the result of the price of products on time.
Análise comparativa da gera??o de fumos entre arames maci?os (GMAW) e tubulares (FCAW)
Garcia, Regina Paula;Scotti, Américo;
Soldagem & Inspe??o , 2010, DOI: 10.1590/S0104-92242010000200004
Abstract: the gmaw (mig /mag) process is widespread in industry. however, it presents limitations regarding metallurgical aspects and geometrical characteristics of the weld bead. the fcaw process, on the other hand, due to presence of fluxes, achieves improvements on these aspects, but the flux might be responsible for larger fume emission. this paper aimed to present a comparative study of fume generation between the gmaw process with short-circuit metal transfer and the gas shielded fcaw process, using wires of same class of resistance (483 mpa of ultimate tension) and application. the experiments were performed in a fume chamber calibrated according to a standard. both wires were evaluated using 100% co2 as the shielding gas and at two current levels. the arc length effect and the use of another shielding gas (25% co2 in argon) were also evaluated. appropriate conditions of contact-tip-to-work-piece distance and arc voltage were selected for each wire-shielding gas combination as a means of making the comparison closer to the reality. the volume of the weld beads per meter was made the same for each level of current, by keeping the same relationship between wire deposition and welding travel speed. the results confirm a higher fume generation rate of the fcaw process (already expected) and that absolute fume generation rate grows as the welding current increases. however, for the gmaw process, analyzed from a relative point of view, it doesn't happen. it was verified that the current effect is more significant on the fcaw process. the increase in the co2 content raised the fume generation rate only for the fcaw process, whilst the arc voltage variation did not demonstrate any effect on it.
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