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Search Results: 1 - 10 of 1381 matches for " Reena Garg "
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Polarization studies in a computer based laboratory
Amit Garg,Reena Sharma,Vishal Dhingra
Latin-American Journal of Physics Education , 2011,
Abstract: This didactic activity is based on computer based learning through sensors and advanced tools for data acquisition and analysis. The fundamental studies related to polarization namely Malus’ Law and study of elliptical and circular polarization have been automated using rotary motion and light sensor. This computer based laboratory allows a student to online collect, analyze and display the data during experimentation leading to better understanding of otherwise a very difficult concept of polarization. Also, time required for carrying out the study of elliptical and circular polarization is substantially reduced from 3 hours to less than half an hour.
Computer assisted magnetism studies
Amit Garg, Reena Sharma,Vishal Dhingra
Latin-American Journal of Physics Education , 2010,
Abstract: The basic objective of this pedagogical activity on magnetism studies is to expose students to a computer assisted learning environment by using various sensors and advanced tools for data acquisition and analysis. Three important studies namely magnetic field variation in different types of disk magnets, solenoid and electromagnetic induction have been done using magnetic field, motion and voltage sensors. This automation of experiments allows a student to continuously acquire and analyse the data online during experimentation leading to better conceptual understanding.
Prospective Development of Small Molecule Targets to Oncogenic Ras Proteins  [PDF]
Reena Chandrashekar, Paul D. Adams
Open Journal of Biophysics (OJBIPHY) , 2013, DOI: 10.4236/ojbiphy.2013.34025
Abstract:

Abnormal expression or mutations in Ras proteins has been found in up to 30% of cancer cell types, making them excellent protein models to probe structure-function relationships of cell-signaling processes that mediate cell transformtion. Yet, there has been very little development of therapies to help tackle Ras-related diseased states. The development of small molecules to target Ras proteins to potentially inhibit abnormal Ras-stimulated cell signaling has been conceptualized and some progress has been made over the last 16 or so years. Here, we briefly review studies characterizing Ras protein-small molecule interactions to show the importance and potential that these small molecules may have for Ras-related drug discovery. We summarize recent results, highlighting small molecules that can be directly targeted to Ras using Structure-Based Drug Design (SBDD) and Fragment-Based Lead Discovery (FBLD) methods. The inactivation of Ras oncogenic signaling in vitro by small molecules is currently an attractive hurdle to try to and leap over in order to attack the oncogenic state. In this regard, important features of previously characterized properties of small molecule Ras targets, as well as a current understanding of conformational and dynamics changes seen for Ras-related mutants, relative to wild type, must be taken into account as newer small molecule design strategies towards Ras are developed.

Multiple z-Score Based Method for Noninvasive Prenatal Test Using Cell-Free DNA in Maternal Plasma  [PDF]
Hyuk Jung Kwon, Amit Goyal, Heesu Im, Kichan Lee, Seon Young Yun, Yoon Hee Kim, Sungjong Lee, Mi-Gyeong Lee, Hyuna Lee, Reena Garg, Boram Park, Soyoung Choi, Joungsu Joo, Jin-Sik Bae, Min-Jeong Kim, Min Seob Lee, Sunghoon Lee
Open Journal of Genetics (OJGen) , 2017, DOI: 10.4236/ojgen.2017.71001
Abstract: Objective: To improve the detecting accuracy of chromosomal aneuploidy of fetus by non-invasive prenatal testing (NIPT) using next generation sequencing data of pregnant women’s cell-free DNA. Methods: We proposed the multi-Z method which uses 21 z-scores for each autosomal chromosome to detect aneuploidy of the chromosome, while the conventional NIPT method uses only one z-score. To do this, mapped read numbers of a certain chromosome were normalized by those of the other 21 chromosomes. Average and standard deviation (SD), which are used for calculating z-score of each sample, were obtained with normalized values between all autosomal chromosomes of control samples. In this way, multiple z-scores can be calculated for 21 autosomal chromosomes except oneself. Results: Multi-Z method showed 100% sensitivity and specificity for 187 samples sequenced to 3 M reads while the conventional NIPT method showed 95.1% specificity. Similarly, for 216 samples sequenced to 1 M reads, Multi-Z method showed 100% sensitivity and 95.6% specificity and the conventional NIPT method showed a result of 75.1% specificity. Conclusion: Multi-Z method showed higher accuracy and robust results than the conventional method even at low coverage reads.
Phototherapy: An update
Rai Reena
Indian Journal of Dermatology, Venereology and Leprology , 2009,
Abstract:
Ocular involvement in a case of scleroderma
Anand Reena
Indian Journal of Ophthalmology , 1985,
Abstract:
Editorial
George Reena
Indian Journal of Palliative Care , 2003,
Abstract:
Doubly disadvantaged - dying of cervical cancer
George Reena
Indian Journal of Palliative Care , 2005,
Abstract:
′Watch with me′: Essays by Cicely Saunders
George Reena
Indian Journal of Palliative Care , 2004,
Abstract:
TRADITIONAL KNOWLEDGE AND PROBLEMS INVOLVED IN MUGA CULTURE OF ASSAM : A CASE STUDY OF GOLAGHAT DISTRICT
Reena Chetia
International Journal for Basic Sciences and Social Sciences , 2013,
Abstract: The golden Muga silk Culture of Assam is as old as Assamese culture. Even today it occupies a very important place in life and culture of Assamese people. Muga silk is a symbol of rich Assamese culture and a part of traditional attire of this region. It is a pride of Assam. Presently, Muga culture has been providing bread and butter to nearly 30,000 families in Assam alone. Assam is the largest silk producing state in the country alone contributes about 99% of the total muga raw silk production. The Muga silk cloth is considered as the Queen of all fabric due to its durability and elegant lustrous natural colour. Muga silk is supposed to be one of the costliest fabrics in the textile world. There is a bright prospect of Muga culture in the North –Eastern part of India including Assam.In this article an attempt has been made to highlights the traditional knowledge involved in Muga culture among rearers of Assam and to find out what type of problems they have to faced by this unique culture. The study is based upon both primary and secondary data. The primary data was collected with the help of questionnaires and interview schedule. Secondary sources of data were collected from Regional Sericulture Research Station Rohroiya, Jorhat , Central Muga Eri Research and Training Institute Lahdoigarh, Jorhat, Department of Sericulture Golaghat, Directorate of Economic and Statistics, Golaghat. Data also collect from various books, journals both official and non official records and newspaper etc.
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