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Search Results: 1 - 10 of 6242 matches for " Raul Cavalcante;Matos Vinagre "
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Efeitos do treinamento resistido na lipoproteína de baixa densidade
Silva, Jeferson Luis da;Maranh?o, Raul Cavalcante;Matos Vinagre, Carmen Guilherme Christiano de;
Revista Brasileira de Medicina do Esporte , 2010, DOI: 10.1590/S1517-86922010000100014
Abstract: the benefits of exercise regular practice are clearly established in the literature. however, the choice of the ideal exercise may be more beneficial for individuals with specific diseases and associated pathologies. the aim of this review was to determine whether resistance training (rt) promotes any change on low density lipoprotein cholesterol. important differences were observed in research protocols, making it difficult to define the benefits of rt in this review. however, it was noticed that rt may be promising in reducing ldl-c levels mainly in adult men and women, in patients with diabetes mellitus type 1 and type 2 and in pre-menopausal women, not presenting differences in the elderly population. it was concluded that the rt is an option good of physical exercise for individuals, especially when the aerobic training (at) is contra-indicated.
Metabolism of a lipid nanoemulsion resembling low-density lipoprotein in patients with grade III obesity
Dantas, Simone Alves;Ficker, Elisabeth Salvatori;Vinagre, Carmen G. C.;Ianni, Barbara Maria;Maranh?o, Raul Cavalcante;Mady, Charles;
Clinics , 2010, DOI: 10.1590/S1807-59322010000100005
Abstract: introduction: obesity increases triglyceride levels and decreases high-density lipoprotein concentrations in plasma. artificial emulsions resembling lipidic plasma lipoprotein structures have been used to evaluate low-density lipoprotein metabolism. in grade iii obesity, low density lipoprotein metabolism is poorly understood. objective: to evaluate the kinetics with which a cholesterol-rich emulsion (called a low-density emulsion) binds to low-density lipoprotein receptors in a group of patients with grade iii obesity by the fractional clearance rate. methods: a low-density emulsion was labeled with [14c]-cholesterol ester and [3h]-triglycerides and injected intravenously into ten normolipidemic non-diabetic patients with grade iii obesity [body mass index higher than 40 kg/m2] and into ten non-obese healthy controls. blood samples were collected over 24 hours to determine the plasma decay curve and to calculate the fractional clearance rate. results: there was no difference regarding plasma levels of total cholesterol or low-density lipoprotein cholesterol between the two groups. the fractional clearance rate of triglycerides was 0.086 ± 0.044 in the obese group and 0.122 ± 0.026 in the controls (p = 0.040), and the fractional clearance rate of cholesterol ester (h-1) was 0.052 ± 0.021 in the obese subjects and 0.058 ± 0.015 (p = 0.971) in the controls. conclusion: grade iii obese subjects exhibited normal low-density lipoprotein removal from plasma as tested by the nanoemulsion method, but triglyceride removal was slower.
Platelet Indices in Patients with Acute Coronary Syndrome  [PDF]
Silvia Cristina Costa, Carmen Guilherme de Matos Vinagre, Ana Paula Marte Chacra, Maria Regina Andrade de Azevedo
Journal of Biosciences and Medicines (JBM) , 2015, DOI: 10.4236/jbm.2015.311009
Abstract: The platelet indices Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Plate-letcrit (PCT) provided by automated hematology analysis are rarely used in clinical practice. Platelets play a central role in the pathogenesis of acute coronary syndromes (ACS) and high MPV has been associated to more reactive platelets and regarded as an independent risk factor for myocardial infarction. In this study, platelet indices were evaluated in 39 patients with ACS presenting two altered biochemical parameters, C reactive protein (CRP) and creatine kinase fraction MB (CK-MB). The results obtained showed significantly higher MPV and PDW values in the group with ACS in comparison to the control group. Also observed was a weak but significant positive correlation between MPV and CK-MB. In view of findings of previous studies, which have associated macroplatelets with higher thrombotic potential our results suggest that the use of the MPV and PDW indices as additional and complementary markers may contribute to the investigation and follow-up of thrombotic risk in patients with ACS.
Expression of sugarcane genes induced by inoculation with Gluconacetobacter diazotrophicus and Herbaspirillum rubrisubalbicans
Nogueira Eduardo de Matos,Vinagre Fabiano,Masuda Hana Paula,Vargas Claudia
Genetics and Molecular Biology , 2001,
Abstract: Several Brazilian sugarcane varieties have the ability to grow with little addition of inorganic nitrogen fertilizers, showing high contributions of Biological Nitrogen Fixation (BNF). A particular type of nitrogen-fixing association has been described in this crop, where endophytic diazotrophs such as Gluconacetobacter diazotrophicus and Herbaspirillum spp. colonize plant tissues without causing disease symptoms. In order to gain insight into the role played by the sugarcane in the interaction between this plant and endophytic diazotrophs, we investigated gene expression profiles of sugarcane plants colonized by G. diazotrophicus and H. rubrisubalbicans by searching the sugarcane expressed sequence tag SUCEST Database (http://sucest.lad.ic.unicamp.br/en/). We produced an inventory of sugarcane genes, candidates for exclusive or preferential expression during the nitrogen-fixing association. This data suggests that the host plant might be actively involved in the establishment of the interaction with G. diazotrophicus and H. rubrisubalbicans.
O papel do estresse oxidativo na DPOC: conceitos atuais e perspectivas
Cavalcante, Antonio George de Matos;Bruin, Pedro Felipe Carvalhedo de;
Jornal Brasileiro de Pneumologia , 2009, DOI: 10.1590/S1806-37132009001200011
Abstract: worldwide, copd is a major cause of morbidity and mortality. the clinical and functional manifestations of copd result from lung injury occurring through various mechanisms, including oxidative stress, inflammation, protease-antiprotease imbalance and apoptosis. oxidative stress is central to the pathogenesis of copd, since it can directly damage lung structures and exacerbate the other mechanisms involved. the cellular and molecular events involved in such lung injury are believed to occur long before the clinical and functional expression of copd. although the use of bronchodilators is currently the principal treatment for copd, bronchodilators have little or no effect on disease progression. a better understanding of the pathogenesis of copd, together with renewed efforts in basic and clinical research, will allow the diagnosis of copd at a pre-clinical stage and provide more appropriate monitoring of disease activity, as well as leading to the development of novel therapeutic agents that will effectively prevent the progression of the disease.
Reproductive Biology, Mating Behavior, and Vibratory Communication of the Brown-Winged Stink Bug, Edessa meditabunda (Fabr.) (Heteroptera: Pentatomidae)
Cleonor Cavalcante A. Silva,Raul Alberto Laumann,Jonatas Barbosa Cavalcante Ferreira,Maria Carolina Blassioli Moraes,Miguel Borges,Andrej okl
Psyche , 2012, DOI: 10.1155/2012/598086
Abstract: We describe different aspects of the reproductive biology, mating behavior, and vibratory communication of the pentatomid Edessa meditabunda (Fabr.). This species shows lower copulation frequency and reproductive potential with longer sexual maturation period compared to other species of pentatomids. Females with multiple mating show increased fecundity when compared with single-mated females and both increased fecundity and reduced longevity when compared with virgin females. Courtship and mating behavior and vibratory signals are typical and similar to what was observed in other species of pentatomids, except that males started the courtship. These results constitute the first paper on biology, behavior, and vibratory communication among species of the subfamily Edessinae.
Transferência de lípides para a lipoproteína de alta densidade (HDl) em mulheres com diabetes melito tipo 1
Feitosa, Alina Coutinho Rodrigues;Maranh?o, Raul Cavalcante;Feitosa Filho, Gilson Soares;Wajchenberg, Bernardo Léo;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2009, DOI: 10.1590/S0004-27302009000100014
Abstract: introduction: people with type 1 diabetes mellitus (t1dm) have an increased risk of cardiovascular disease and may still have a normal lipid profile. in order to clarify whether normal hdl cholesterol levels may conceal defects in hdl function, we have studied the transfer of lipids to hdl in t1dm. methods: twenty-one young women with t1dm were compared with 21 non-diabetic women. nanoemulsion preparations were used as lipid donor to hdl: one labeled with 3h-triglycerides and 14c-free cholesterol and the other with 3h-cholesteryl esters and 14c-phospholipids. these preparations were incubated with plasma samples for 1h. after chemical precipitation, the supernatant containing hdl was counted for radioactivity. results: no difference in transfer was observed to nanoemulsion hdl from cholesteryl esters, triglycerides, free cholesterol and phospholipids. conclusion: simultaneous lipid transfer to hdl was not affected in t1dm patients. this suggests that the disease does not alter lipoprotein composition and transfer protein action in such way as to disturb hdl metabolism.
Estenose aórtica e doen?a coronariana: análise dos fatores de risco
Rangel, Claudio Magalh?es;Grinberg, Max;Maranh?o, Raul Cavalcante;Ventura, Laura Inês;
Arquivos Brasileiros de Cardiologia , 2006, DOI: 10.1590/S0066-782X2006001500008
Abstract: objective: to analyze clinical laboratorial aspects of the presence of coronary disease in patients with aortic stenosis and evaluate the influence of risk factors in the development of obstructive coronary disease. methods: we studied 65 patients who had severe aortic stenosis with an indication for surgery, ages 51 to 85 years, 40 of them women. the coronary angiography assessment resulted in two groups: 26 (40%) with obstructive coronary disease and 39 (60%) with no coronary artery lesion. personal antecedents for coronary disease (smoking, dyslipidemia, diabetes mellitus, arterial hypertension, family antecedents, sedentarism, and alcoholism) were analyzed. additionally, the following assessments were made: electrocardiogram, echocardiogram with doppler, and laboratory tests (blood glucose, total cholesterol and fractions, triglycerides, apo-a1 and b, fibrinogen, lipoprotein (a) and fraction of triglycerides and cholesterol removal in both groups. results: in the age analysis, the group with obstructive coronary disease belonged to an older age range with statistical significance (p<0.0001). signs of ischemia of the anterior wall identified on the electrocardiogram showed a significant relationship with the obstruction of an anterior interventricular artery (p<0.002). the univariate analysis showed a significant difference between the groups regarding averages of the aortic (p= 0.041), hdl (p=0.042), and fibrinogen (p=0.047) gradients. the group with coronary disease presented an average gradient and hdl level lower than the group without obstructive coronary disease. for the fibrinogen variable, the average in the group with no coronary disease was lower compared to that of the coronariopathy group. the multivariate logistic regression analysis showed fibrinogen levels as an independent variable for coronary disease (p<0.039). conclusion: fibrinogen was an independent risk factor for the association between obstructive coronary disease and aortic stenosis.
Euschistus heros mass rearing technique for the multiplication of Telenomus podisi
Silva, Cleonor Cavalcante;Laumann, Raul Alberto;Blassioli, Maria Carolina;Pareja, Martin;Borges, Miguel;
Pesquisa Agropecuária Brasileira , 2008, DOI: 10.1590/S0100-204X2008000500004
Abstract: the objective of this work was to improve the mass rearing technique of euschistus heros in laboratory. nymphs and adults were reared at densities 100, 200, 300 and 400 eggs per petri dish (9 cm diameter), and at 50, 100, 150 and 200 couples per rearing cages (900 ml), respectively. survival rate of immature stages and survivorship and reproduction of adults were determinated. survivorship of nymph to adult was the highest (89%) at density 100 eggs per dish. adult survivorship was independent of density, and 100 couples per cage were the best to improve quality of the produced progeny. in these conditions, fecundity was 160.8±9.28 eggs per female, and a total of 8,950±456 eggs per cage per month was produced. two hundred couples per cage showed a negative effect on reproduction, which decreased to 65%. with this technique, a colony of 35 cages with 100 couples per cage yields about 313.3 thousands eggs per month, which is enough to supply the egg parasitoid telenomus podisi to colonize about 35 ha of soybean field.
Amphotericin B associated with triglyceride-rich nanoemulsion: stability studies and in vitro antifungal activity
Filippin, Fabíola Branco;Souza, Liliete Canes;Maranh?o, Raul Cavalcante;
Química Nova , 2008, DOI: 10.1590/S0100-40422008000300024
Abstract: amphotericin b (ab) is the standard drug for invasive fungal infection therapy. it has a broad spectrum of activity and it is the best antifungal available against most yeasts and molds. its therapeutic use, however, is limited by significant side effects, leading to a low therapeutic index when it is used as the traditional formulation (fungizone?). due to self-association, ab can form pores in cholesterol-containing membranes. we propose a triglyceride-rich nanoemulsion as a delivery system for ab in low levels of aggregation to reduce the toxicity against host cells.
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