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Search Results: 1 - 8 of 8 matches for " Rajah Pravartani Vati "
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PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND ANTHELMINTIC ACTIVITY OF MORINGA OLEIFERA LEAVES
Srinivasa U,Amrutia Jay N,Katharotiya Reena,Moses Semuel Rajan
International Research Journal of Pharmacy , 2011,
Abstract: Petroleum ether, chloroform, methanol and aqueous extracts of leaves of Moringa oleifera were screened for various bioactive constituents like glycosides, carbohydrates, tannins, flavonoids, triterpenoids and alkaloids. The chloroform and methanol extracts were evaluated for anthelmintic activity on adult Indian earthworms Pheritima postuma using Piperazine citrate and Rajah Pravartani Vati (Ayurvedic preparation) as a reference standards. The results obtained indicated that the chloroform extract was more potent compared to other extracts.
DIURESIS: EXPERIMENTAL EVIDENCE OF POLYHERBALS IN ALBINO RATS
Kumawat Mukesh K,Kamble Mahesh K,Gumate Dipak S,Naikwade Nilofar S
International Research Journal of Pharmacy , 2011,
Abstract: Numerous medicinal plants and their formulations are used for various disorders in ethno medical practices as well in the traditional system of medicine in India. The Vrukkadoshantake vati (VV) and Nephrovin (NEP) are ayurvedic polyherbal formulations and are used in alternative system of medicine for treatment of urinary disorder. No data is available for its efficacious use in urinary disorders. The Lipschits method was used for collection of supportive data for diuretic action of the Vrukkadoshantake vati and Nephrovin. Wistar albino rats were fasted for 18 h prior to experiment and aqueous suspensions of the formulations were administered at the graded doses of 200, & 400mg/kg body weight. After the treatment, urine was collected for 24h and diuretic activity was assessed by evaluation of the total volume of urine, Na+, K+, Cl- concentration and also the Diuretic index, Nariuretic effect, & saluretic effect were calculated. The total urine volume of the rats treated with the aqueous suspensions of the formulations (400 mg/kg) were found to be nearly two fold (p<0.05) when compared with the control (saline treated) group. Excretion of cations (sodium and potassium ions) and anions (chloride ions) was also found to be increased significantly (p<0.01) with respect to the control group. The diuretic effect was comparable with that of the standard drug Furosemide.
PHARMACOLOGICAL ACTIVITIES OF POLYHERBAL FORMULATION: SANJIVANI VATI
S Gairola,Vikas Gupta,Parveen Bansal,M Maithani
International Journal of Ayurvedic Medicine , 2011,
Abstract:
EVALUATION OF CARDIOPROTECTIVE ACTIVITY OF MEDOHAR VATI BY ISOPROTERENOL INDUCED MYOCARDIAL DAMAGE IN RATS
Patel Jignasa S,Setty Seema K,Chakraborty Manodeep,Kamath Jagadish V
International Research Journal of Pharmacy , 2012,
Abstract: This study was designed to investigate the cardioprotective activity of poly herbal formulation Medohar vati in isoproterenol (ISO)- induced myocardial necrosis in rats. Animals were treated with Medohar vati (150 and 300 mg/kg for 21 days) and Carvedilol (10mg/kg for 7 days) to the rats treated with ISO (85 mg/kg, sc) on the 22th and 23rd days. The group only treated with ISO demonstrated elevated level of Lactate dehydrogenasa (LDH), Creatine kinase (CK-MB) and CK- NAC in serum which was restored with all the prophylactic treated groups such as Carvedilol and both the doses of Medohar vati. Similarly the abnormal electocardiographic changes like RR and PR interval, QRS duration, QT segment was normalized by Carvedilol and with both the doses of Medohar vati. The results were supported by the histopathological analysis. To conclude Medohar vati was found to be cardioprotective against ISO induced myocardial damage in rats.
PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF TRIPHALAGUDUCHYADI VATI: AN EFFECTIVE FORMULATION FOR OBESITY
Biju K.R,Shukla V.J.,Harisha C.R.,Patel K.S.
International Journal of Research in Ayurveda and Pharmacy , 2011,
Abstract: Childhood obesity is one among the most serious public health challenges of the 21st century. Lots of single and compound drugs have been described in Ayurvedic classics for the management of Obesity. Triphalaguduchyadi churnna is one among them and is very safe to be used in children. The drug having Kaphamedohara and lekhana properties is effective in Sthaulya (Obesity). Tannin, the main chemical constituent of the drug regulates food intake and is a proven hypolipidaemic agent. To overcome the problems of palatability, feasibility, shelf life with the churnna form of drug, an effort is made to convert it into convenient tablet form. This paper is prepared with a view to standardize the product through pharmacognostical and pharmaceutical measures. The compound was analyzed and standardized scientifically through qualitative and quantitative analysis by physico-chemical parameters, Thin Layer Chromatography (TLC), High Performance Thin Layer Chromatography (HPTLC) and pharmacognostical measures. Pharmacognostical analysis showed characteristics of all the ingredient drugs in the tablet. Pharmaceutical analysis revealed the presence of tannin, glycosides and flavanoids with tannin as the main constituent that accounts 34.26%w/w of the compound. TLC and HPTLC were carried out after organizing appropriate solvent system in which 8 and 7spots were distinguished in TLC and HPTLC respectively. It is inferred that the formulation meets the minimum qualitative standards as reported in the API at a preliminary level. The inference from this study may be used as reference standard in the further quality control researches.
A COMPARATIVE CLINICAL STUDY ON VICHARCHIKA VIS-à-VIS ALLERGIC CONTACT DERMATITIS
R.C Mythrey,S.Nisargi Ramachandra,S Geetha Kumari
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: Allergic contact dermatitis is becoming a common skin problem all over the world. It accounts for about 4-7% of all dermatological problems. This is due to a delayed hypersensitivity reaction following contact with antigens. Hypersensitivity to chemicals appears to become a serious health problem for the general population, particularly in their work environment it will be the most incapacitating condition as a consequence of skin being exposed to chemical agents. Allergic contact dermatitis is characterized by erythema, scaling, edema, vesiculation and oozing. Itching varies from mild to severe. These features can be correlated with vicharchika. So in order to manage vicharchika in terms of Allergic contact dermatitis, a comparative study was done to evaluate the effect of virechana and shamanaushadhis. Group A was given virechana followed by shamanoushadhis i.e., Laghu sootashekara vati and Nava kwatha along with Manjishtadi taila for external application for 30days. Group B was given only shamanoushadhis for 30 days. The efficacy of the treatment was assessed by noting the prime lakshanas of vicharchika like shyava varna, pidaka, kandu and srava before and after the treatment and statistically analysed using student ‘t’ test. After treatment it is observed that, both shodhana chikitsa and shamana chikitsa have their own role in the management of vicharchika. Even statistically, both are having highly significant values within the individual groups. But when both shodhana and shamana treatment are statistically compared, they show no significant values which means that both are effective with no significant difference between them.
PHARMACOGNOSTICAL AND PHYTO-CHEMICAL EVALUATION OF PUNARNAVADI MANDURA: AN EFFECTIVE FORMULATION FOR IRON DEFICIENCY ANEMIA
Kori Virendra Kumar,Patel Kalpana S,Shukla V J,Harisha C R
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: Iron deficiency anemia affects millions of people worldwide. Children and women of reproductive age are at increased risk. Iron deficiency is harmful at all ages. In young children it impairs physical growth, cognitive development, immunity and at school age it affects school performance. At adulthood it causes fatigue, reduced work capacity and in pregnant women, anemia leads to fetal growth retardation, low birth weight and maternal death. Punarnavadi Mandura Vati is a herbo-miniral formulation indicated for the management of Pandu (Anaemia). Pharmacognostical evaluation of Punarnavadi Mandura Vati exposed acicular crystals, sclerides, beaker shape Stone cell, pitted vessels, starch with parenchymal cells, resin contents etc. which are the characteristics of the drug. Organo-leptic features of coarse powder were within the standard range. High- Performance Thin Layer Chromatography Study showed 5 spots corresponding to hRf values 0.30, 0.66, 0.70, 0.76, 0.85 in short wave UV 254 nm, and 2 spots corresponding to hRf values 0.31, 0.69 obtained in long wave UV 366 nm.
A COMPARATIVE STUDY OF LEKHAN THERAPY IN THE MANAGEMENT OF STHOULYA (OBESITY)
Nayak Annada Prasad
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: Obesity is the world’s oldest metabolic disorder. The WHO now considers obesity to be a Global epidemic and a public health problem. Globally an estimated 300 million adults are now obese and many are overweight. Prominent health risks associated with obesity are hypertension, type-2 diabetes mellitus, dyslipidemia, stroke, gall bladder stone, osteoarthritis, respiratory problem etc. As per Ayurveda, Acharya Charak has counted Sthoulya under the eight varieties of impediments which are designated as Nindita Purusha. According to Chikitsa Sutra of this disease, Lekhan therapy is an important therapeutic measure in Sthoulya as said by Acharya Charka. Moreover lekhan basti is the other and most effective therapy in the management of Sthoulya.To assess the effect of lekhan therapy by two therapeutic modules, 24 Sthoulya patients were selected for this study and were divided into two groups. Group A patients were given 15 lekhan basti in alternate day. After completion of basti, lekhan vati was given for two months. In group B, patients were given lekhan vati for three months, which was selected from Ca.Su.4:9 as lekhaneeya dasemani and is added with Varun and Vidang. The effects of two therapeutic modules were assessed statistically based on the Performa prepared. This was a humble effort to compare the effect of lekhan basti and lekhan vati in the management of Sthoulya. In this study we have found that lekhan basti followed by lekhan vati was more effective in combating the disease than only lekhan vati therapy.
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