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Search Results: 1 - 10 of 360105 matches for " Raimundo N.;D?bereiner "
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Ocorrência e distribui??o de esporos de Clostridium botulinum tipos C e D em áreas de cria??o de búfalos na Baixada Maranhense
Silva, Tania M.D.;Dutra, Iveraldo S.;Castro, Raimundo N.;Dbereiner, Jürgen;
Pesquisa Veterinária Brasileira , 1998, DOI: 10.1590/S0100-736X1998000300007
Abstract: as botulism is a common disease in buffaloes raised in the low lands of the state of maranh?o, brazil, the occurrence of clostridium botulinum spores was evaluated in buffalo breeding areas of 4 municipalities in the "baixada maranhense". twenty eight samples of faeces, mud and soil were collected and divided into 140 subsamples, being 40 of faeces, 65 of mud and 35 of soil. botulinum toxin was detected in the filtrates of 104 cultures (74.28%) from 140 subsamples through the inoculation of mice. using the microcomplement fixation technique for the identification of c. botulinum toxins, type c (14.29%), d (82.14%) and cd complex (3.57%) were found. no significant differences (p>0.05%) between faeces, mud and soil samples were observed. there was a high contamination with c. botulinum spores of the buffalo faeces, mud and soil in the areas studied. identification of other types and subtypes of c. botulinum was not attempted.
Ocorrência e distribui o de esporos de Clostridium botulinum tipos C e D em áreas de cria o de búfalos na Baixada Maranhense
Silva Tania M.D.,Dutra Iveraldo S.,Castro Raimundo N.,Dbereiner Jürgen
Pesquisa Veterinária Brasileira , 1998,
Abstract: Botulismo é enzoótico na cria o de búfalos da Baixada Maranhense, Estado do Maranh o. No presente trabalho foram realizados estudos para verificar a ocorrência e distribui o de esporos de Clostridium botulinum tipos C e D em amostras de solo, limo e fezes de búfalos, colhidas aleatoriamente em áreas inundáveis da cria o de búfalos nessa Baixada. A evidencia o de esporos foi realizada em 40 amostras de fezes, 65 de limo e 35 de solo, provenientes de quatro municípios, pelo cultivo em meio de cultura com carne cozida e posterior inocula o do sobrenadante filtrado em camundongo, na tentativa de verifica o da presen a de toxina botulínica. A tipifica o de amostras positivas foi realizada pela microfixa o de complemento. Os resultados revelaram que 104 (74,28%) das 140 amostras examinadas foram positivas para a presen a de esporos de C. botulinum pelo teste indireto. N o houve diferen a significativa (P>0,05) entre os valores obtidos quando das análises das amostras de solo (77,1%), limo (60,0%) e fezes (95,0%). Das 28 amostras de solo, limo e fezes positivas, que foram utilizadas para a tipifica o, quatro (14,29%) foram classificadas como tipo C, 23 (82,14%) como tipo D e uma (3,5%) como pertencente ao complexo CD. Os resultados revelaram uma alta contamina o ambiental por C. botulinum em áreas de cria o de búfalos da Baixada Maranhen-se. A identifica o de outros tipos e de subtipos de C. botulinum n o foi realizada.
Surto de intoxica??o por narasina em suínos
Armién, Aníbal G.;Peixoto, Paulo Vargas;Dbereiner, Jürgen;Tokarnia, Carlos H.;
Pesquisa Veterinária Brasileira , 1997, DOI: 10.1590/S0100-736X1997000200004
Abstract: an outbreak of narasin poisoning in swine is described. the diagnosis was based on the history, clinical-pathological findings, the reproduction of the disease by the administration of the feed originally given to the animals and by chemical analysis which showed doses sufficiently high to cause poisoning. inspite that the clinical-pathological picture of the natural and experimental poisoning was of the same nature, there were some differences. in the natural outbreak lethality was high, but in the experiments none of the animals died. in the natural cases besides the lesions in the muscles, also lesions of the heart muscle fibres were seen, not detected in the esperimental animals. it is suggested that these differences could be due to the stress to which the animals were submitted in the piggery by the great number of animals per box, whereas the experimental animals were kept individually.
Surto de intoxica o por narasina em suínos
Armién Aníbal G.,Peixoto Paulo Vargas,Dbereiner Jürgen,Tokarnia Carlos H.
Pesquisa Veterinária Brasileira , 1997,
Abstract: Descreve-se um surto de intoxica o por narasina em suínos, cujo diagnóstico baseou-se no histórico, quadro clínico-patológico, na reprodu o da enfermidade pela experimenta o com a ra o comercial originalmente oferecida aos suínos, bem como pelo exame químico posterior que detectou narasina em quantidades suficientemente elevadas para causar intoxica o. Apesar de os quadros clínico-patológicos das intoxica es natural e experimental serem da mesma natureza, houve algumas diferen as. Nos casos naturais o índice de letalidade foi elevado, enquanto que na intoxica o experimental nenhum animal morreu. Os exames histopatológicos revelaram, em parte dos casos naturais, além das les es dos músculos estriados, também les es nas fibras musculares cardíacas, últimas n o verificadas nos casos experimentais. Sugere-se que essas diferen as poderiam ser explicadas pelo estresse ao qual os animais eram submetidos na granja pelo grande número de animais nas baias, ao contrário dos animais experimentais que eram mantidos em compartimentos individuais.
Aspectos clínico-patológicos da intoxica o experimental por selenito de sódio em eqüinos
Néspoli Pedro Brandini,Duarte Marcos Dutra,Bezerra Jr Pedro Soares,Dbereiner Jürgen
Pesquisa Veterinária Brasileira , 2001,
Abstract: Dadas as controvérsias sobre a intoxica o por selênio, foram realizados nove experimentos com a administra o de selenito de sódio, por via intramuscular, em eqüinos, com o intuito de estudar e melhor fundamentar os aspectos clínico-patológicos e toxicológicos sobre esse tema. Conseguiram-se produzir quadros com evolu es superaguda, aguda, subaguda e cr nica; alguns sinais clínicos de origem nervosa observados nos quadros agudos foram similares aos descritos para "blind staggers"; a despeito disto, o carácter conflitante e duvidoso das descri es sobre essa pretensa entidade historicamente descrita, n o permite uma compara o mais exata. O quadro cr nico, por outro lado, configurou claramente a primeira reprodu o de "alkali disease", por via parenteral, em eqüinos. Estabeleceu-se 1,49 mg/kg de selenito de sódio como a dose única letal para essa espécie. Descrevem-se diversos achados clínico-patológicos relativos aos sistemas cardiovascular e nervoso, antes n o mencionados na literatura relativa aos eqüinos intoxicados por selênio. Entre eles, destacam-se, clinicamente, sopro e arritmia cardíacos, desdobramento de bulhas e convuls o. à necropsia, um animal apresentou nítido achatamento das circunvolu es cerebrais e, em rela o à histopatologia, lise e necrose de neur nios do córtex, edema de astrócitos, bem como ativa o endotelial e gliose. Em rela o à patogênese, postula-se que as altera es degenerativo-necróticas observadas no sistema nervoso central, devam-se ao edema, por sua vez conseqüente ao aumento da permeabilidade vascular, determinada pelo selenito de sódio.
Aspectos clínico-patológicos da intoxica??o experimental por selenito de sódio em eqüinos
Néspoli, Pedro Brandini;Duarte, Marcos Dutra;Bezerra Jr, Pedro Soares;Dbereiner, Jürgen;Peixoto, Paulo Vargas;
Pesquisa Veterinária Brasileira , 2001, DOI: 10.1590/S0100-736X2001000300003
Abstract: due to the numerous contradictions on selenium poisoining, and in order to improve knowledge about the clinical, pathological and toxicological aspects, experiments were performed with intramuscular injections of sodium selenite in 9 horses. peracute, acute, subacute and chronic poisoning was reproduced; some nervous symptoms observed in acute cases were similar to those described for "blind staggers". in spite of this, the conflicting and dubious feature of this formerly described disease turns very difficult any comparison. on the other hand, the chronic poisoning was the first experimental reproduction of "alkali disease" by the parenteral route in horses. when administered as one injection, the lethal dose for sodium selenite was 1.49 mg/kg. various clinical and pathological observations regarding the cardiovascular and nervous system, not previously mentioned in the literature for horses, are described. there have to be mentioned especially, (1) as to clinical aspects, cardiac murmurs, arrythmia, splitting of the heart sounds and convulsions, (2) regarding post-mortem findings, flattening of the cerebral gyri and increase of the liquor, and (3) concerning histopathology, lysis and necrosis of neurons in the cortex, oedema of astrocytes, as well as activation of endothelial and glia cells. it is suggested, that the degenerative-necrotic alterations in the central nervous system could be due to the oedema caused by an increase in vascular permeability through the action of the selenite.
Estudos complementares sobre a toxidez de Lantana camara (Verbenaceae) em bovinos
Tokarnia, Carlos Hubinger;Armién, Anibal Guillermo;Barros, Severo Sales de;Peixoto, Paulo Vargas;Dbereiner, Jürgen;
Pesquisa Veterinária Brasileira , 1999, DOI: 10.1590/S0100-736X1999000300007
Abstract: an outbreak of poisoning by lantana camara var. aculeata in cattle was diagnosed in the county of quatis, state of rio de janeiro. the animals, after travelling by foot, were put, hungry, for a few days, on a pasture highly infested by the plant. the toxicity of the plant was proved experimentally in cattle; also experiments to see how far the plant has cumulative properties, were performed. the plant caused lethal poisoning when given as a single dose of 40 g/kg; 20 g/kg caused severe poisoning, 10 g/kg slight or no poisoning and 5 g/kg failed to provoke symptoms. a lethal result was produced also when 10 g/kg per day was given over 4 days. the administration of 5 g/kg per day caused severe poisoning when fed over 5 days to two calves. the dose of 2.5 g/kg fed daily over 7 or 9 days also produced severe poisoning in two calves; in another calf, severe symptoms were produced only after feeding 2.5 g/kg per day for 19 days; still another calf showed no symptoms after 32 days of feeding 2,5 g/kg per day, although twice the lethal dose had been fed by this time. a dose of 1.25 g/kg per day over 34 days also failed to produce any symptoms.
Surtos de Enteropatia Proliferativa Hemorrágica (Lawsonia intracelullaris) em suínos no Estado do Rio de Janeiro
Fran?a, Ticiana N.;Ribeiro, Carlos T.;Bezerra Jr, Pedro S.;Dbereiner, Jürgen;Cerqueira, Valíria D.;Peixoto, Paulo V.;
Pesquisa Veterinária Brasileira , 2008,
Abstract: outbreaks of infection of swine with lawsonia intracelullaris in the state of rio de janeiro are described. the symptomathology was characterized by bloody diarrhea with peracute course. postmortem findings were pale organs and tissues, reticulate aspect of the ileum with its mucosa moderately thickened nad contained large amounts of partially coagulated blood. histopathological examination revealed hyperplastic epithelial cell proliferation of the lieberkühn crypts, sometimes associated with inflammatory and necrotic alterations. immunohistochemistry demonstrated the presence of large amounts of bacteria in the cytoplasm of the cryptal epithelial cells. l. intracellularis was also seen by ultramicroscopic examination. these outbreaks occurred in 1987 and this is the first report of the disease in the state of rio de janeiro.
O antagonismo com acetamida em experimentos com ovinos, caprinos e coelhos indica monofluoroacetato como princípio tóxico de Pseudocalymma elegans Bignoniaceae
Helayel, Michel A;Caldas, Saulo A;Peixoto, Tiago C;Fran?a, Ticiana N;Tokarnia, Carlos H;Dbereiner, Jürgen;Nogueira, Vivian A;Peixoto, Paulo V;
Pesquisa Veterinária Brasileira , 2011, DOI: 10.1590/S0100-736X2011001000006
Abstract: this study aimed to evaluate the protective effect of acetamid in experimental poisoning by pseudocalymma elegans in sheep, goats and rabbits, in order to prove indirectly that monofluoroacetate (mf) is responsible for the clinical signs and death of animals that ingested the plant. experiments were performed to determine for sheep and goats the lethal dose of p. elegans collected in rio bonito, rj, in different seasons, and to adjust the dose of acetamid to be administered. - in the first experiment, two sheep and two goats received 1.0g/kg of fresh p. elegans, and two (one sheep and one goat) were pretreated with 2.0g/kg of acetamid. none of the animals showed clinical signs or died. possibly, the plant could be less toxic, since it was collected at the end of the rainy season. - in the second experiment, two sheep and two goats received 0.67 and 1.0g/kg of the dried plant, after pretreatment with 2.0 and 3.0g/kg of acetamid, respectively. all animals died, as the administered doses of p. elegans were very high. - in the third experiment, two sheep and two goats received 0.333g/kg of dried p. elegans after previous administration of 2.0g/kg of acetamid; a week later, the protocol above was repeated, but without the antidote. in experiments with rabbits, doses of 0.5 and 1.0g/kg of dried p. elegans were given after administration of 3.0g/kg of acetamid; seven days later, the same protocol was repeated, except the administration of acetamide. this procedure, when acetamid was administered before, prevented the appearance of clinical signs and death of sheep, goats and rabbits. but the animals not treated with acetamid showed symptoms of poisoning and died. clinically, the sheep and goats had tachycardia, engorged jugular vein, positive venous pulse, lateral recumbence, and muscle tremors. in the "dramatic phase", the animals fell into lateral position, stretched the limbs, were paddling and died within minutes. the rabbits showed apathy, muscle tremors, vocalization
Experimentos em bovinos com as favas de Enterolobium contortisiliquum e E. timbouva para verificar propriedades fotossensibilizantes e/ou abortivas
Tokarnia, Carlos Hubinger;Dbereiner, Jürgen;Dutra, Iveraldo S.;Brito, Ilson S.;Chagas, Bion? R.;Fran?a, Ticiana N.;Brust, Luis A.G.;
Pesquisa Veterinária Brasileira , 1999, DOI: 10.1590/S0100-736X1999000100006
Abstract: the pods of enterolobium spp (leg.mimosoideae) are said to cause photsensitivity and abortion in cattle. the pods of e. contortisiliquum and e. timbouva ("tamboril" or "timbaúba"), collected at various localities, in two occasions during outbreaks of photosensitization and abortions, were fed in single and repeated doses to young bovines and to cows in calf. in all experiments the animals showed only diarrhoea and loss of apetite, as it had been already seen in previous experiments with e. contortisiliquum performed in fortaleza, northeastern brazil. also it was seen again that the animals become tolerant to the toxicity of the pods if they get successive doses. the experiments did not reveal possible conditions necessary for the pods of enterolobium contortisiliquum and e. timbouva to cause photosensitization and/or abortion.
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