oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2020 ( 2 )

2019 ( 160 )

2018 ( 315 )

2017 ( 328 )

Custom range...

Search Results: 1 - 10 of 174681 matches for " Raffaele De Caterina "
All listed articles are free for downloading (OA Articles)
Page 1 /174681
Display every page Item
Antiatherogenic effects of n-3 fatty acids - evidence and mechanisms
Raffaele De Caterina,Antonella Zampolli
Heart International , 2009, DOI: 10.4081/hi.2006.141
Abstract: N-3 (omega-3) (polyunsaturated) fatty acids are thought to display a variety of beneficial effects for human health. Clues to the occurrence of cardiovascular protective effects have been, however, the spur for the first biomedical interest in these compounds, and are the best documented. Historically, the epidemiologic association between dietary consumption of n-3 fatty acids and cardiovascular protection was first suggested by Bang and Dyerberg, who identified the high consumption of fish, and therefore, of fish oil-derived n-3 fatty acids, as the likely explanation for the strikingly low rate of coronary heart disease events reported in the Inuit population. Since their initial reports, research has proceeded in parallel to provide further evidence for their cardioprotection and to understand underlying mechanisms. Decreased atherogenesis is currently thought to be a part of the cardiovascular protection by n-3 fatty acids. This article summarizes the evidence for such a claim and the mechanisms putatively involved. (Heart International 2006; 3-4: 141-54)
MR Angiography, MR Imaging and Proton MR Spectroscopy In-Vivo Assessment of Skeletal Muscle Ischemia in Diabetic Rats
Stefano Delli Pizzi, Rosalinda Madonna, Massimo Caulo, Gian Luca Romani, Raffaele De Caterina, Armando Tartaro
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044752
Abstract: To prospectively evaluate the feasibility of using magnetic resonance (MR) techniques for in-vivo assessing a rat diabetic model of limb ischemia. Unilateral hind limb ischemia was induced by ligation of the iliac-femoral artery in male streptozotocin-treated and non-diabetic control rats. Four weeks after ligation, rats underwent MR Angiography (MRA), T1-weighted and Short Time Inversion Recovery (STIR) sequences and muscle Proton MR Spectroscopy (1H-MRS) on both hind limbs. After MR examinations, immunoblotting and immunofluorescence analysis were performed. MRA showed a signal void due to flow discontinuation distal to the artery ligation. T1-weighted and STIR images showed, respectively, the presence of tissue swelling (p = 0.018 for non-diabetic; p = 0.027 for diabetic rats) and signal hyperintensity in tissue affected by occlusion. Mean total creatine/water for the occluded limb was significantly lower than for the non-occluded limbs in both non-diabetic (5.46×10?4 vs 1.14×10?3, p = 0.028) and diabetic rats (1.37×10?4 vs 1.10×10?3; p = 0.018). MR Imaging and 1H-MRS changes were more pronounced in diabetic than in non-diabetic occluded limbs (p = 0.032). MR findings were confirmed by using histological findings. Combined MR techniques can be used to demonstrate the presence of structural and metabolic changes produced by iliac-femoral artery occlusion in rat diabetic model of limb ischemia.
Governmental Leadership without a Political Party  [PDF]
Raffaele De Mucci
Open Journal of Political Science (OJPS) , 2018, DOI: 10.4236/ojps.2018.83020
Abstract: This article focuses on the theme of strengthening government leadership within contemporary democracy schemes, irrespective of their forms of Government-parliamentary or presidential. They are, in most cases, leaders-without-party in the sense that, though (formally) sponsored by a political party, they manage to impose and legitimize themselves by virtue of their personalities along with a team of loyal followers, doing without their own party and often opposing to it. This phenomenon of leadership concentration” of the head of Government is evident even in parliamentary systems whereaccording with the Germanys historical prototypeis defined as a “chancellor democracy”. We can get many examples of this tendency around the world in the latest ten years.
Comparison between Two FT-IR Spectroscopy Analytical Procedures for Micrograms Determination of Asbestos Species in Bulk Materials  [PDF]
Luca De Stefano, Raffaele Cioffi, Francesco Colangelo
American Journal of Analytical Chemistry (AJAC) , 2012, DOI: 10.4236/ajac.2012.31001
Abstract: The Fourier Transform Infrared (FT-IR) spectroscopy is by far known to be a useful technique for qualitative and quantitative analysis of asbestos in bulk samples, since all asbestos species exhibit intense absorption peaks in the 4000 - 400 cm-1 region of the infrared spectrum. In the present work, we compare the accuracy and precision of two analytical procedures (the Linear Calibration Curve Method and the Method of Addition) for the quantitative determination of asbestos in a host matrix. We have found that, providing careful samples preparation, both techniques quantify the asbestos content at the level of few micrograms with good precision. Due to less expensive equipment requirements and shorter analysis time, FT-IR can be a competitive analytical technique in the characterization of asbestos containing material with the respect to diffractometry or electron microscopy.
Clinical experience with apixaban in atrial fibrillation: implications of AVERROES
De Caterina R
Research Reports in Clinical Cardiology , 2011, DOI: http://dx.doi.org/10.2147/RRCC.S17434
Abstract: ical experience with apixaban in atrial fibrillation: implications of AVERROES Commentary (2989) Total Article Views Authors: De Caterina R Published Date July 2011 Volume 2011:2 Pages 83 - 86 DOI: http://dx.doi.org/10.2147/RRCC.S17434 Raffaele De Caterina Institute of Cardiology and Center of Excellence on Aging, G d’Annunzio University, Chieti, G Monasterio Foundation, Pisa, Italy Abstract: Atrial fibrillation is an extremely common arrhythmia, which substantially increases the risk of stroke and thromboembolism. Prevention of stroke and thromboembolism is therefore an important part of the management of atrial fibrillation. Guidelines until now have recommended that patients with atrial fibrillation receive some form of antithrombotic therapy, ie, a vitamin K antagonist or aspirin, with a preference for anticoagulants in most cases. However, current treatments are suboptimal, and despite the recommendations, many patients do not receive adequate thromboprophylaxis, because they are considered, for various reasons, “unsuitable” to receive a vitamin K antagonist. In this patient population, apixaban, a new oral anticoagulant inhibiting activated coagulation factor X, administered in fixed doses and without anticoagulation monitoring, has undergone testing against aspirin in the recently published AVERROES trial. This paper addresses the strengths and limitations of this trial and the practical relevance of the new clinical information it provides.
Clinical experience with apixaban in atrial fibrillation: implications of AVERROES
De Caterina R
Research Reports in Clinical Cardiology , 2011,
Abstract: Raffaele De CaterinaInstitute of Cardiology and Center of Excellence on Aging, G d’Annunzio University, Chieti, G Monasterio Foundation, Pisa, ItalyAbstract: Atrial fibrillation is an extremely common arrhythmia, which substantially increases the risk of stroke and thromboembolism. Prevention of stroke and thromboembolism is therefore an important part of the management of atrial fibrillation. Guidelines until now have recommended that patients with atrial fibrillation receive some form of antithrombotic therapy, ie, a vitamin K antagonist or aspirin, with a preference for anticoagulants in most cases. However, current treatments are suboptimal, and despite the recommendations, many patients do not receive adequate thromboprophylaxis, because they are considered, for various reasons, “unsuitable” to receive a vitamin K antagonist. In this patient population, apixaban, a new oral anticoagulant inhibiting activated coagulation factor X, administered in fixed doses and without anticoagulation monitoring, has undergone testing against aspirin in the recently published AVERROES trial. This paper addresses the strengths and limitations of this trial and the practical relevance of the new clinical information it provides.Keywords: atrial fibrillation, apixaban, thromboprophylaxis
Direito e Modernidade
Raffaele de Giorgi
Sequência : Estudos Juridicos e Politicos , 1997,
Abstract:
O risco na sociedade contemporanea
Raffaele de Giorgi
Sequência : Estudos Juridicos e Politicos , 1994,
Abstract:
Opposite Roles of NMDA Receptors in Relapsing and Primary Progressive Multiple Sclerosis
Silvia Rossi, Valeria Studer, Alessandro Moscatelli, Caterina Motta, Giancarlo Coghe, Giuseppe Fenu, Stacy Caillier, Fabio Buttari, Francesco Mori, Francesca Barbieri, Maura Castelli, Valentina De Chiara, Fabrizia Monteleone, Raffaele Mancino, Giorgio Bernardi, Sergio E. Baranzini, Maria G. Marrosu, Jorge R. Oksenberg, Diego Centonze
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0067357
Abstract: Synaptic transmission and plasticity mediated by NMDA receptors (NMDARs) could modulate the severity of multiple sclerosis (MS). Here the role of NMDARs in MS was first explored in 691 subjects carrying specific allelic variants of the NR1 subunit gene or of the NR2B subunit gene of this glutamate receptor. The analysis was replicated for significant SNPs in an independent sample of 1548 MS subjects. The C allele of rs4880213 was found to be associated with reduced NMDAR-mediated cortical excitability, and with increased probability of having more disability than the CT/TT MS subjects. MS severity was higher in the CC group among relapsing-remitting MS (RR-MS) patients, while primary progressive MS (PP-MS) subjects homozygous for the T allele had more pronounced clinical worsening. Mean time to first relapse, but not to an active MRI scan, was lower in the CC group of RR-MS patients, and the number of subjects with two or more clinical relapses in the first two years of the disease was higher in CC compared to CT/TT group. Furthermore, the percentage of relapses associated with residual disability was lower in subjects carrying the T allele. Lesion load at the MRI was conversely unaffected by the C or T allele of this SNP in RR-MS patients. Axonal and neuronal degeneration at the optical coherence tomography was more severe in the TT group of PP-MS patients, while reduced retinal nerve fiber thickness had less consequences on visual acuity in RR-MS patients bearing the T allele. Finally, the T allele was associated with preserved cognitive abilities at the Rao’s brief repeatable neuropsychological battery in RR-MS. Signaling through glutamate NMDARs enhances both compensatory synaptic plasticity and excitotoxic neurodegeneration, impacting in opposite ways on RR-MS and PP-MS pathophysiological mechanisms.
Infinite groups with many generalized normal subgroups
Francesco de Giovanni,Caterina Rainone
International Journal of Group Theory , 2012,
Abstract: A subgroup $X$ of a group $G$ is almost normal if the index $|G:N_G(X)|$ is finite, while $X$ is nearly normal if it has finite index in the normal closure $X^G$. This paper investigates the structure of groups in which every (infinite) subgroup is either almost normal or nearly normal.
Page 1 /174681
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.