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Search Results: 1 - 10 of 103589 matches for " Qiufang Zhang "
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Emotional Context Influences Micro-Expression Recognition
Ming Zhang, Qiufang Fu, Yu-Hsin Chen, Xiaolan Fu
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0095018
Abstract: Micro-expressions are often embedded in a flow of expressions including both neutral and other facial expressions. However, it remains unclear whether the types of facial expressions appearing before and after the micro-expression, i.e., the emotional context, influence micro-expression recognition. To address this question, the present study used a modified METT (Micro-Expression Training Tool) paradigm that required participants to recognize the target micro-expressions presented briefly between two identical emotional faces. The results of Experiments 1 and 2 showed that negative context impaired the recognition of micro-expressions regardless of the duration of the target micro-expression. Stimulus-difference between the context and target micro-expression was accounted for in Experiment 3. Results showed that a context effect on micro-expression recognition persists even when the stimulus similarity between the context and target micro-expressions was controlled. Therefore, our results not only provided evidence for the context effect on micro-expression recognition but also suggested that the context effect might result from both the stimulus and valence differences.
Association of the genetic variants of luteinizing hormone, luteinizing hormone receptor and polycystic ovary syndrome
Nana Liu, Yanmin Ma, Shuyu Wang, Xiaowei Zhang, Qiufang Zhang, Xue Zhang, Li Fu, Jie Qiao
Reproductive Biology and Endocrinology , 2012, DOI: 10.1186/1477-7827-10-36
Abstract: 315 PCOS women and 212 controls were screened for the gene variants of LH G1052A and LHR rs61996318 polymorphisms by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP).PCOS patients had significantly more A allele frequency of LH G1052A mutations than controls (p=0.001). Within PCOS group, carriers of LH 1052A allele had lower LH (p=0.05) and higher fasting glucose levels (p=0.04). No subjects were identified with LHR rs61996318 polymorphisms. A new LHR single nucleotide polymorphism (SNP) was found without clear association with PCOS.Results suggested LH G1052A mutation might influence PCOS susceptibility and phenotypes.
Association of TRB3 Q84R polymorphism with polycystic ovary syndrome in Chinese women
Xue Zhang, Li Fu, Qiufang Zhang, Liying Yan, Yanmin Ma, Binbin Tu, Nana Liu, Jie Qiao
Reproductive Biology and Endocrinology , 2011, DOI: 10.1186/1477-7827-9-46
Abstract: A case-control study with two groups: PCOS group (n = 336) and control group of infertility women for tubal and/or male factor (n = 116) was performed. Genotyping of the TRB3 R84 variant was determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).The frequency of genotype QQ in PCOS women was significantly lower, while genotype QR and RR were significantly higher than that in control group (p < 0.05). However, the difference disappeared after adjustment for BMI. At glucose1h, glucose2h and insulin2h point, the difference between QQ individuals and R84 allele carriers in PCOS women reached statistical significance during OGTT (p < 0.05).TRB3 Q84R polymorphism is associated with obesity and especially glucose metabolism and not associated with polycystic ovary syndrome because of compositional characteristics of phenotype in Chinese PCOS women.Polycystic ovary syndrome (PCOS) is a common endocrine disorder with amenorrhoea (or oligomenorrhoea), hyperandrogenism, hirsutism, obesity and insulin resistance (IR). It affects 5-10% reproductive aged women and is a leading cause of female infertility [1]. It is a complex and heterogeneous disorder due to the interaction of multiple genetic defects and environmental factors [2]. Candidate genes for etiology of PCOS involve in ovarian and adrenal steroidogenesis, steroid hormone actions, gonadotropin action and regulation, insulin action and secretion, energy homeostasis, chronic inflammation and others [3]. Insulin resistance is a pathophysiological contributor in around 50% to 80% of women with PCOS [4]. It is well established that hyperinsulinemia and insulin resistance are common biochemical features of PCOS independent of obesity [5]. Insulin resistance is associated with hyperandrogenemia and anovulation in PCOS women [6,7]. As is well known, hyperandrogenism and anovulation are important clinical features and diagnostic criteria for polycystic ovary syndrome [8]. Besides, PCOS women a
Effect of Pullulan Nanoparticle Surface Charges on HSA Complexation and Drug Release Behavior of HSA-Bound Nanoparticles
Xiaojun Tao, Qiufang Zhang, Kai Ling, Yicun Chen, Wenzhi Yang, Fenfei Gao, Ganggang Shi
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0049304
Abstract: Nanoparticle (NP) compositions such as hydrophobicity and surface charge are vital to determine the presence and amount of human serum albumin (HSA) binding. The HSA binding influences drug release, biocompatibility, biodistribution, and intercellular trafficking of nanoparticles (NPs). Here, we prepared 2 kinds of nanomaterials to investigate HSA binding and evaluated drug release of HSA-bound NPs. Polysaccharides (pullulan) carboxyethylated to provide ionic derivatives were then conjugated to cholesterol groups to obtain cholesterol-modified carboxyethyl pullulan (CHCP). Cholesterol-modified pullulan (CHP) conjugate was synthesized with a similar degree of substitution of cholesterol moiety to CHCP. CHCP formed self-aggregated NPs in aqueous solution with a spherical structure and zeta potential of ?19.9±0.23 mV, in contrast to ?1.21±0.12 mV of CHP NPs. NPs could quench albumin fluorescence intensity with maximum emission intensity gradually decreasing up to a plateau at 9 to 12 h. Binding constants were 1.12×105 M?1 and 0.70×105 M?1 to CHP and CHCP, respectively, as determined by Stern-Volmer analysis. The complexation between HSA and NPs was a gradual process driven by hydrophobic force and inhibited by NP surface charge and shell-core structure. HSA conformation was altered by NPs with reduction of α-helical content, depending on interaction time and particle surface charges. These NPs could represent a sustained release carrier for mitoxantrone in vitro, and the bound HSA assisted in enhancing sustained drug release.
Icariin Protects Rat Cardiac H9c2 Cells from Apoptosis by Inhibiting Endoplasmic Reticulum Stress
Qiufang Zhang,Hongliang Li,Shanshan Wang,Ming Liu,Yibin Feng,Xuanbin Wang
International Journal of Molecular Sciences , 2013, DOI: 10.3390/ijms140917845
Abstract: Endoplasmic reticulum stress (ERS) is one of the mechanisms of apoptotic cell death. Inhibiting the apoptosis induced by ERS may be a novel therapeutic target in cardiovascular diseases. Icariin, a flavonoid isolated from Epimedium brevicornum Maxim, has been demonstrated to have cardiovascular protective effects, but its effects on ERS are unknown. In the present study, we focused on icariin and investigated whether it might protect the cardiac cell from apoptosis via inhibition of ERS. In H9c2 rat cardiomyoblast cells, pretreatment of icariin significantly inhibited cell apoptosis by tunicamycin, an ERS inducer. Icariin also decreased generation of reactive oxygen species (ROS), loss of mitochondrial membrane potential and activation of caspase-3. Moreover, icariin inhibited upregulation of endoplasmic reticulum markers, GRP78, GRP94 and CHOP, elicited by tunicamycin. These results indicated that icariin could protect H9c2 cardiomyoblast cells from ERS-mitochondrial apoptosis in vitro, the mechanisms may be associated with its inhibiting of GRP78, GRP94 and CHOP and decreasing ROS generation directly. It may be a potential agent for treating cardiovascular disease.
Profiling the ionome of rice and its use in discriminating geographical origins at the regional scale, China
Gang Li,Luis Nunes,Yijie Wang,Paul N Williams,Maozhong Zheng,Qiufang Zhang,Yongguan Zhu,
Gang Li
,Luis Nunes,Yijie Wang,Paul N. Williams,Maozhong Zheng,Qiufang Zhang,Yongguan Zhu

环境科学学报(英文版) , 2013,
Abstract: Element profile was investigated for their use to trace the geographical origin of rice (Oryza sativa L.) samples. The concentrations of 13 elements (calcium (Ca), potassium (K), magnesium (Mg), phosphorus (P), boron (B), manganese (Mn), iron (Fe), nickel (Ni), copper (Cu), arsenic (As), selenium (Se), molybdenum (Mo), and cadmium (Cd)) were determined in the rice samples by inductively coupled plasma optical emission and mass spectrometry. Most of the essential elements for human health in rice were within normal ranges except for Mo and Se. Mo concentrations were twice as high as those in rice from Vietnam and Spain. Meanwhile, Se concentrations were three times lower in the whole province compared to the Chinese average level of 0.088 mg/kg. About 12% of the rice samples failed the Chinese national food safety standard of 0.2 mg/kg for Cd. Combined with the multi-elemental profile in rice, the principal component analysis (PCA), discriminant function analysis (DFA) and Fibonacci index analysis (FIA) were applied to discriminate geographical origins of the samples. Results indicated that the FIA method could achieve a more effective geographical origin classification compared with PCA and DFA, due to its efficiency in making the grouping even when the elemental variability was so high that PCA and DFA showed little discriminatory power. Furthermore, some elements were identified as the most powerful indicators of geographical origin: Ca, Ni, Fe and Cd. This suggests that the newly established methodology of FIA based on the ionome profile can be applied to determine the geographical origin of rice.
January to August temperature variability since 1776 inferred from tree-ring width of Pinus tabulaeformis in Helan Mountain

CAI Qiufang,LIU Yu,

地理学报 , 2007,
Abstract: Tree-ring standardized chronologies are developed by 78 cores collected from the eastern and western Helan Mountain. Statistical analysis shows that both the STD and RES chronologies correlate negatively with the temperature of different periods of early half year, especially with January to August mean (JA) temperature, which means that JA temperature is one of the predominant limiting factors of tree growth in the Helan Mountain. Based on this analysis, we reconstructed JA temperature, and the explained variance is 43.3% (F=21.422, p<0.001). The comparatively high temperature periods in the reconstruction were: 1805?1818, 1828–1857, 1899–1907, 1919–1931 and 1968–1995; and the comparatively low temperature periods happened in 1858–1872, 1883–1895 and 1935–1953. Ten-year moving average curve shows three slow uplifting trends: 1766–1853, 1862–1931 and 1944–1995. Each tem-perature increase was followed by a sudden temperature decrease about 10 years, that is to say, the JA temperature in the Helan Mountain is characterized by slow increase and sudden decrease. The 70- and 10.77-year periodicities detected in the temperature series correspond to the Gleissberg (80-year) and Schwabe (11-year) periodicities of solar activity respectively, the 2.11–2.62 years cycles are considered to be influenced by QBO (Quasi-Bie- nnial-Oscillation) and the local environmental change.
Implicit Learning of Recursive Context-Free Grammars
Martin Rohrmeier, Qiufang Fu, Zoltan Dienes
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0045885
Abstract: Context-free grammars are fundamental for the description of linguistic syntax. However, most artificial grammar learning experiments have explored learning of simpler finite-state grammars, while studies exploring context-free grammars have not assessed awareness and implicitness. This paper explores the implicit learning of context-free grammars employing features of hierarchical organization, recursive embedding and long-distance dependencies. The grammars also featured the distinction between left- and right-branching structures, as well as between centre- and tail-embedding, both distinctions found in natural languages. People acquired unconscious knowledge of relations between grammatical classes even for dependencies over long distances, in ways that went beyond learning simpler relations (e.g. n-grams) between individual words. The structural distinctions drawn from linguistics also proved important as performance was greater for tail-embedding than centre-embedding structures. The results suggest the plausibility of implicit learning of complex context-free structures, which model some features of natural languages. They support the relevance of artificial grammar learning for probing mechanisms of language learning and challenge existing theories and computational models of implicit learning.
The interaction between cognition and emotion
Ye Liu,QiuFang Fu,XiaoLan Fu
Chinese Science Bulletin , 2009, DOI: 10.1007/s11434-009-0632-2
Abstract: Cognition and emotion have long been thought of as independent systems. However, recent research in the cognitive and neurobiological sciences has shown that the relationship between cognition and emotion is more interdependent than separate. Based on evidence from behavioral and neuroscientific research, researchers have realized that it is necessary to propose a new conceptual framework to describe the relationship between cognition and emotion. In this article, recent research from behavioral, neuroscientific and developmental research on the interaction between cognition and emotion is summarized, and how the interaction of cognition and emotion might affect computer science and artificial intelligence is discussed. It especially focuses on the implications for affective computing.
Tree-ring-based May–July mean temperature history for Lüliang Mountains, China, since 1836
QiuFang Cai,Yu Liu,Guang Bao,Ying Lei,Bo Sun
Chinese Science Bulletin , 2010, DOI: 10.1007/s11434-010-3235-z
Abstract: As a consequence of recent global warming and its social impact, regional climate change is attracting an increasing amount of attention from scientists. A May–July temperature proxy extending back to 1836 was developed from tree-ring width of Chinese pine (Pinus tabulaeformis Carr.) found in the middle Lüliang Mountains, northern China. Correlations with climatic data from six nearby meteorological stations range from 0.58 to 0.65, indicating a strong response of tree-ring index to May–July mean temperatures, which were subsequently reconstructed. The reconstruction captures 45% (F=38.474, P<0.001) of the regional variance in the instrumental data over the calibration period 1955–2003. Reconstructed warm and cold periods were verified by additional temperature reconstructions based on tree-ring data from northern China. In addition, the reconstruction was significantly correlated with May–July mean temperatures from 13 other meteorological stations in northern China, suggesting that our reconstruction is also representative of north-central China. The warming trend during the second half of the 20th century is seen in the reconstruction, but only the 1994–2002 mean temperature seems unprecedented over the whole reconstructed period.
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