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Search Results: 1 - 10 of 39572 matches for " Priscila Pereira Costa;Akashi "
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Schwannomas in the head and neck: retrospective analysis of 21 patients and review of the literature
Langner, Erwin;Del Negro, André;Akashi, Hugo Kenzo;Araújo, Priscila Pereira Costa;Tincani, Alfio José;Martins, Antonio Santos;
Sao Paulo Medical Journal , 2007, DOI: 10.1590/S1516-31802007000400005
Abstract: context and objective: schwannomas are benign neoplasms of the peripheral nerves originating in the schwann cells. according to their cellularity, they can be subdivided into antoni a or antoni b types. they are rare and usually solitary, with clearly delimited capsules. they occur in the head and neck region in only 25% of the cases, and may be associated with von recklinghausen's disease. the present study retrospectively analyzed some data on this disease in the head and neck region and reviewed the literature on the subject. design and setting: retrospective study at head and neck service, universidade estadual de campinas. methods: data on 21 patients between 1980 and 2003 were reviewed. the sites of cervical schwannomas and the intraoperative, histopathological and postoperative clinical status of these cases were studied. diagnostic methods, type of surgery and association with neurofibromatosis were evaluated. results: the patients' ages ranged from 16 to 72 years. four patients had a positive past history of type i neurofibromatosis or von recklinghausen's disease. the nerves affected included the brachial and cervical plexuses, vagus nerve, sympathetic chain and lingual or recurrent laryngeal nerve. the nerve of origin was not identified in six cases. tumor enucleation was performed in 16 patients; the other five required more extensive surgery. conclusion: schwannomas and neurofibromas both derive from schwann cells, but are different entities. they are solitary lesions, except in von recklinghausen's disease. they are generally benign, and rarely recur. the recommended surgical treatment is tumor enucleation.
Management of salivary gland adenoid cystic carcinoma: institutional experience of a case series
Tincani, Alfio José;Del Negro, André;Araújo, Priscila Pereira Costa;Akashi, Hugo Kenzo;Martins, Antonio Santos;Altemani, Albina Milani;Barreto, Gilson;
Sao Paulo Medical Journal , 2006, DOI: 10.1590/S1516-31802006000100006
Abstract: context and objective: salivary gland tumor management requires long-term follow-up because of tumor indolence and possible late recurrence and distant metastasis. adenoid cystic carcinoma (acc) accounts for 10-15% of such tumors. the aim here was to evaluate surgical and clinical management, staging and follow-up of acc patients in one academic institution. design and setting: retrospective study at head and neck service, universidade estadual de campinas. methods: data on 21 patients treated between 1993 and 2003 were reviewed. management utilized clinical staging, histology and imaging. major salivary gland tumor extent was routinely assessed by preoperative ultrasonography. diagnosis, surgery type, margin type (negative/positive), postoperative radiotherapy and recurrence (presence/absence) were evaluated. results: there were eleven major salivary gland tumors (52.3%), seven submandibular and four parotid. ten patients (47.7%) had minor salivary gland acc (all in palate), while the submandibular was the most frequently affected major one. diagnoses were mostly via fine-needle aspiration (fna) and incision biopsy. frozen sections were used for six patients. there was good ultrasound/fna correlation. sixteen (76%) had postoperative radiotherapy. one (4.7%) died from acc and five now have recurrent disease: three (14.2%) locoregional and two (9.5%) distant metastases. conclusion: adenoid cystic carcinoma has locally aggressive behavior. in 21 cases, of acc, the facial nerve was preserved in all except in the few with gross tumor involvement. treatment was defined from physical examination, imaging, staging and histology.
Head and neck reconstruction using infrahyoid myocutaneous flaps
Tincani, Alfio José;Del Negro, André;Araújo, Priscila Pereira Costa;Akashi, Hugo Kenzo;Neves, Flávia da Silva Pinto;Martins, Ant?nio Santos;
Sao Paulo Medical Journal , 2006, DOI: 10.1590/S1516-31802006000500007
Abstract: context and objective: the use of pedicled myocutaneous flaps in head and neck reconstruction is widely accepted. here we describe our experience with infrahyoid flaps (ihfs) employed to cover surgical defects in the oral cavity and oropharynx in patients with benign and malignant tumors. the aim was to evaluate the success rate for infrahyoid myocutaneous flap procedures performed at a single institution. design and setting: retrospective study, at the head and neck surgery service, unicamp. methods: fourteen ihfs were used to reconstruct surgical defects in eleven men (78.5%) and three women (21.5%) with a mean age of 66.4 years. the anterior floor of the mouth was reconstructed in nine patients (64.2%), the base of tongue in three (21.4%), the lateral floor in one (7.1%), and the retromolar area (7.1%) in one. thirteen patients (92.8%) had squamous cell carcinoma (scc) and one (7.2%) ameloblastoma. the disease stage was t3 in eight (61.5%) of the scc cases and t4 in five (38.5%). results: no patient presented total flap loss or fistula. the most common complication was epidermolysis, which delayed the beginning of oral ingestion. the patients with scc received postoperative radiotherapy without major consequences to the flap. conclusion: ihf is a safe and reliable procedure for reconstructing head and neck surgical defects. due to its thinness and malleability, its use for oral cavity and oropharynx defects provides favorable cosmetic and functional outcomes. complications, when present, are easy to manage.
Produ??o de micropartículas de alginato contendo Flavobacterium columnare inativada pelo método de emuls?o para vacina??o de peixes por via oral
Sacchetin, Priscila Soares Costa;Moraes, ?ngela Maria;Leal, Carlos Augusto Gomes;Figueiredo, Henrique César Pereira;
Química Nova , 2010, DOI: 10.1590/S0100-40422010000200006
Abstract: alginate microparticles were prepared by an emulsion method aiming oral controlled release of antigens to fish. the effects of emulsification temperature and impeller type on particle morphology, average diameter, and size distribution were evaluated. microparticles contaning formalin-killed flavobacterium columnare cells (a model antigen) were prepared and characterized regarding bacterial release and particle stability when exposed to nile tilapia (oreochromis niloticus) typical gastrointestinal conditions. this methodology allowed the production of microparticles containing up to 14.3 g/l of bacterin, stable at a ph range from 2.0 to 9.0 for 12 h and smaller than 35 μm.
Lingual thyroid causing dysphonia: case report
Tincani, Alfio José;Martins, Antonio Santos;Del Negro, André;Araújo, Priscila Pereira Costa;Barretto, Gilson;
Sao Paulo Medical Journal , 2004, DOI: 10.1590/S1516-31802004000200007
Abstract: context: lingual thyroid gland is a rare clinical entity that is caused by the failure of the thyroid gland to descend to a normal cervical location during embryogenesis. the occurrence of an ectopic thyroid gland located at the base of the tongue may cause problems for the patient, with symptoms of dysphagia, dysphonia, upper airway obstruction or even hemorrhage at any time from infancy through adulthood. case report: we report on a case of lingual thyroid gland in a 41-year-old female patient. the embryology and diagnosis of ectopic thyroid are discussed and its management is outlined. features of the diagnostic and therapeutic evaluation are described with attention to the clinical findings, laboratory tests, thyroid scan and computed tomography imaging studies employed in the confirmation of diagnosis and planning of appropriate treatment. the history of the condition is reviewed and a treatment strategy is outlined. surgical excision of the gland is reserved for cases of gland enlargement that result in compromised airways (dysphagia or dysphonia) or recurrent hemorrhage.
Structural and Functional Analysis of Human SOD1 in Amyotrophic Lateral Sclerosis
Lorenna Giannini Alves Moreira, Livia Costa Pereira, Priscila Ramalho Drummond, Joelma Freire De Mesquita
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0081979
Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with familial inheritance (fALS) in 5% to 10% of cases; 25% of those are caused by mutations in the superoxide dismutase 1 (SOD1) protein. More than 100 mutations in the SOD1 gene have been associated with fALS, altering the geometry of the active site, protein folding and the interaction between monomers. We performed a functional analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in 124 fALS SOD1 mutants. Eleven different algorithms were used to estimate the functional impact of the replacement of one amino acid on protein structure: SNPs&GO, PolyPhen-2, SNAP, PMUT, Sift, PhD-SNP, nsSNPAnalyzer, TANGO, WALTZ, LIMBO and FoldX. For the structural analysis, theoretical models of 124 SNPs of SOD1 were created by comparative modeling using the MHOLline workflow, which includes Modeller and Procheck. Models were aligned with the native protein by the TM-align algorithm. A human-curated database was developed using the server side include in Java, JMOL. The results of this functional analysis indicate that the majority of the 124 natural mutants are harmful to the protein structure and thus corroborate the correlation between the reported mutations and fALS. In the structural analysis, all models showed conformational changes when compared to wild-type SOD1, and the degree of structural alignment varied between them. The SOD1 database converge structural and functional analyses of SOD1; it is a vast resource for the molecular analysis of amyotrophic lateral sclerosis, which allows the user to expand his knowledge on the molecular basis of the disease. The SOD1 database is available at http://bioinfogroup.com/database.
Similaridade genética entre acessos de goiabeiras e ara?azeiros baseada em marcadores moleculares AFLP
Corrêa, Luiz Claudio;Santos, Carlos Antonio Fernandes;Lima, Giuseppina Pace Pereira;Rodrigues, Marciene Amorim;Costa, Tuany Priscila Pereira;
Revista Brasileira de Fruticultura , 2011, DOI: 10.1590/S0100-29452011000300021
Abstract: species of the genus psidium, like guava and brazilian guava trees, are economically important and have the area of primary genetic diversity in brazil. it was determined the genetic relationships based on aflp marker for accessions of psidium germplasm bank (pgb) of embrapa semiarid to guide improvements and management of genetic resources of the genus. eighty-eight accessions were analyzed, 64 of guava and 24 of brazilian guava, collected in ten brazilian states, adopting for the cluster dendrogram upgma, considering the similarity matrix of jaccard's coefficient of 149 polymorphic aflp bands from 16 combinations of primers ecori and msei. analysis of variance of molecular data was performed considering the variation between and within populations of guava from the ten states. the dendrogram showed good definition, with cophenetic coefficient of 0.94. two major groups were identified: one formed by accessions of guava and other with access to brazilian guava, including some accessions of guava. specific groups were observed in the dendrogram only for individuals guava collected in goias and roraima. these accessions showed similarity ranging from 28 to 98%, suggesting a high genetic variability of them. the variation among accessions was estimated at 0.16 (φst), indicating moderate genetic differentiation among guava populations from the ten states. to increase the genetic variability of the abg studied, it is suggested to collect more hits in the states of goiás and roraima, due to the high degree of similarity among accessions from these states, as well as extensive collections in other brazilian states. crosses among the few accessions of guava which are positioned in the group of brazilian guava were also suggested for the development of interspecific hybrids in the genus psidium.
Lazer, agressividade e violência: considera??es sobre o comportamento das torcidas organizadas
Palhares, Marcelo Fadori Soares;Schwartz, Gisele Maria;Teruel, Ana Paula;Santiago, Danilo Roberto Pereira;Trevisan, Priscila Raquel Tedesco da Costa;
Motriz: Revista de Educa??o Física , 2012, DOI: 10.1590/S1980-65742012000100019
Abstract: soccer has a great social representation in many cultures. but the passion developed in the fans can born aggressive and violent behaviors in a moment that should be for fun, characterizing the deviant leisure, theme that needs more investigation. this qualitative research has a main goal to investigate, in the academics studies, the aggressive behavior of the organized fans and their consequences in the leisure time. by a bibliographical research, information were found in reference material, composed by books and thesis, besides the use of databases, with the key-words: leisure, cheerleaders, aggressiveness and violence. the results show that, independently of the genesis of an aggressive behavior, other factors could interfere. when inside a group, or depending on the social-historical context, the profile of the fans, the violence of each society, the media, the poor organization of sport and impunity, these factors can affect individual behavior, contributing to aggressive and violent manifestations in soccer context, inside the field and inside the organizations of the fans. this kind of manifestation leads to a smaller audience at the stadiums, and even creating limitations in activities of leisure context. these violent conducts can bring serious physics and/or psychological consequences. after all, is pointed the necessity of specific public policies involving leisure and the international events.
Spatio-Temporal Variations of Microphytobenthos in the Botafogo and Siri estuaries (norteast - Brazil)
Murolo, Priscila Porchat de Assis;Carvalho, Paulo Vladmir Vandenberg da Costa;Carvalho, Monica Lucia Botter;Souza-Santos, Lilia Pereira de;Santos, Paulo Jorge Parreira dos;
Brazilian Journal of Oceanography , 2006, DOI: 10.1590/S1679-87592006000100002
Abstract: spatio-temporal variations of microphytobenthic biomass were investigated in the botafogo and siri estuaries, pernambuco - brazil. samples were taken during low water (bi-monthly) from february to december, 2003. three sampling stations were located in each estuary, in both midlittoral and sublittoral areas. clear spatial and temporal variations were found for both chlorophyll-a and phaeopigment concentrations. in botafogo, chlorophyll-a had 34% of total variation explained by mra from nitrogen and phosphorus concentrations, while only 16% of total variation was thus explained from nitrogen concentration in the siri estuary. phaeopigments had 39% of total variation explained by mra from nitrogen concentration and salinity in the botafogo estuary and 58% of total variation was similarly explained from nitrogen concentration in the siri estuary. nitrogen was discriminated by the b coefficients as the most important factor in the explanation of the microphytobenthic pigments variations in the botafogo estuary. the data of this study emphasize the role of nutrients and suggest that both estuaries show evidence of eutrophication.
Interdisciplinary in Promoting Improvements in the Quality of Undergraduate Education in Clinical Nursing  [PDF]
Diana Paula de Souza Rego Pinto Carvalho, Anna Lúcia Dantas, Anna Larissa de de Castro Rego, Gabriela Assun??o da Costa Mafra Souza, Isabelle Campos de Azevedo, Giovanna Karinny Pereira Cruz, Priscila Fernandes Meireles, Allyne Forte Vitor, Maria Lúcia Ivo, Marcos Antonio Ferreira Júnior
Creative Education (CE) , 2015, DOI: 10.4236/ce.2015.617192
Abstract: The university monitoring is an auxiliary activity of educational support offered to students interested in deepening content and solving questions about the topics learned in the classroom, as well as an opportunity for the development in the student-monitor relationship next to the teaching practice. This study aimed to report the experience lived by the student-monitors linked to monitoring project entitled “Interdisciplinary for improving the quality of education: Physiology, Anatomy and Pathology for Clinical Nursing teaching”. It is an experience report experienced by student-monitors linked to the project developed for curriculum component Comprehensive Health Care I, taught in the fifth period of the Undergraduate Nursing course at the Federal University of Rio Grande do Norte, Brazil. This project has four stages: preparation of laboratories and fellows training, construction and application of clinical cases, development of simulations in the laboratory with the students and the final evaluation of the changing process in curriculum practice. The monitoring project has provided contact with a simulation environment for students, for the development of skills and attitudes in solving clinical nursing problems through an innovative approach to integrating disciplinary learning in the classroom and development initiation skills in student-monitors teaching. The approximate relationship with the teacher allows the exchange of knowledge, which makes proactive student-monitor in the very process of teaching and learning, as well as the teacher provides the formation of a more qualified and secure professional for the exercise of appropriate assistance.
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