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Search Results: 1 - 10 of 13476 matches for " Priscila Garcia;Derchain "
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Carcinoma Microinvasor no Cone Pós Biópsia Dirigida Compatível com NIC 3
Figueiredo Priscila Garcia,Gontijo Renata Clementino,Derchain Sophie Fran?oise Mauricette,Nakano Fabiana Yumi
Revista Brasileira de Ginecologia e Obstetrícia , 2002,
Abstract: Objetivo: determinar os fatores associados ao achado de carcinoma microinvasor no cone de mulheres com biópsia colpodirigida prévia compatível com neoplasia intra-epitelial cervical (NIC) 3 e avaliar a propor o de margens comprometidas. Pacientes e Métodos: foram revisados os prontuários de 385 mulheres (média de idade: 39 anos) submetidas à coniza o a frio ou por cirurgia de alta freqüência (CAF) com al a no período de janeiro de 1993 a julho de 2000. Estes procedimentos foram indicados por biópsia compatível com NIC 3. Resultados: o diagnóstico do cone foi compatível com NIC 3 em 243 mulheres (63%) e com NIC 2 em 13 (3%). Apenas 10 apresentaram HPV/NIC 1 (3%) e oito n o tinham doen a residual no cone. Entretanto, 101 mulheres apresentaram carcinoma microinvasor no cone (26%) e 10 (3%) carcinoma invasor franco. A idade, o estado menstrual e o número de partos n o estiveram relacionados com a gravidade da les o no cone. Mulheres com altera es da colpocitologia oncológica sugestivas de invas o apresentaram um risco significativamente maior de apresentar carcinoma microinvasor ou invasor no histológico final (p<0,01), embora 52 das 243 mulheres com NIC 2 ou NIC 3 no cone também tivessem sugest o de invas o na colpocitologia. Entre as mulheres com NIC 2 ou 3, 44% apresentaram epitélio branco, 21% pontilhado e 17% mosaico. Esta propor o foi semelhante nas mulheres com carcinoma microinvasor ou invasor, sendo estas imagens encontradas, respectivamente, em 37%, 23% e 21%. O comprometimento das margens do cone foi significativamente maior nas mulheres submetidas a CAF (49%) do que naquelas submetidas à coniza o a frio (29%). Conclus o: a ausência de fatores independentes clínicos e colposcópicos que se associam com o achado de carcinomas microinvasivos em mulheres submetidas à coniza o por biópsia compatível com NIC 3 justifica a excis o c nica da jun o escamo-colunar nas les es cervicais de alto grau.
Carga viral do papilomavirus humano na predi??o da gravidade de les?es cervicais em mulheres com atipias celulares na colpocitologia oncológica
Sarian, Luis Otávio Zanatta;Santos, André Luis Ferreira;Derchain, Sophie Fran?oise Mauricette;Figuereido, Priscila Garcia;Morais, Sirlei Siani;
Revista Brasileira de Ginecologia e Obstetrícia , 2003, DOI: 10.1590/S0100-72032003000500010
Abstract: purpose: to assess the performance of hybrid capture ii (hcii) hpv viral load in predicting the grade of cervical lesions. methods: between august 2000 to november 2002, 309 women admitted due to an abnormal pap smear result were recruited. histological disease confirmation was done in all women and cervical intraepithelial neoplasia (cin) grade 2 or above was considered as severe disease. hcii was done for high-risk hpv types and viral load was estimated in relative light units (rlu). receiver operating characteristics analysis was used to test the performance of hcii. results: histological findings included 140 (45.3%) cervicitis or cin 1 and 199 (54.7%) cin 2/3, in situ adenocarcinoma or invasive cancer. the best cutoff for hcii in detecting severe disease was 35 rlu, showing a sensitivity of 69% and a specificity of 70%. association of high-grade cervical lesions at pap smear and hcii at 35 rlu showed a positive predictive value of 88.2% in diagnosis of cin 2 or above. on the other hand, 95.7% of the women with low grade lesion at cytology and hcii below 1 rlu presented no severe histological disease. conclusions: the best performance of hcii in diagnosing cin 2 or above was found at 35 rlu. association of cytology and hcii in different settings provided very high positive and negative predictive values.
Detec o do DNA do papilomavírus humano após excis o da zona de transforma o com al a diatérmica para tratamento de neoplasia intra-epitelial cervical
Figueirêdo Priscila Garcia,Derchain Sophie Fran?oise Mauricette,Sarian Luis Otávio Zanatta,Gontijo Renata Clementino
Revista Brasileira de Ginecologia e Obstetrícia , 2003,
Abstract:
Carga viral do papilomavirus humano na predi o da gravidade de les es cervicais em mulheres com atipias celulares na colpocitologia oncológica
Sarian Luis Otávio Zanatta,Santos André Luis Ferreira,Derchain Sophie Fran?oise Mauricette,Figuereido Priscila Garcia
Revista Brasileira de Ginecologia e Obstetrícia , 2003,
Abstract: OBJETIVO: avaliar o desempenho da carga viral do HPV por captura de híbridos II (CHII) na predi o da gravidade das les es cervicais. MéTODOS: foram incluídas 309 mulheres admitidas por resultado anormal da colpocitologia oncológica (CO) entre agosto de 200 e novembro de 2002. Todas foram submetidas a avalia o histológica, sendo que a presen a de neoplasia intra-epitelial cervical (NIC) grau 2 ou mais (NIC 3, carcinoma invasor) foi considerada doen a grave. A CHII foi realizada para tipos de HPV de alto risco oncogênico e a carga viral medida em unidades relativas de luz (URL). O desempenho da CHII foi avaliado por curva receiver operating characteristics (ROC). RESULTADOS: na avalia o histológica, 140 (45,3%) mulheres apresentavam cervicite ou NIC 1 e 199 (54,7%), NIC 2/3, adenocarcinoma in situ ou cancer invasor. O melhor ponto de corte da CHII para a detec o de doen a grave foi 35 URL, com sensibilidade de 69% e especificidade de 70%. O valor preditivo positivo das altera es compatíveis com les o de alto grau na CO associado a CHII de 35 URL (unidades relativas de luz) foi de 88,2% para a detec o de NIC 2 ou mais. Já 95,7% das mulheres com les es de baixo grau na CO e CHII menor que 1 URL n o apresentaram les es histológicas graves. CONCLUS O: o melhor desempenho da CHII no diagnóstico de NIC 2 ou les o mais grave foi encontrado com 35 URL. A associa o da CO com a CHII em diferentes cargas virais mostrou valores preditivos positivos e negativos muito altos.
Carcinoma Microinvasor no Cone Pós Biópsia Dirigida Compatível com NIC 3
Figueiredo, Priscila Garcia;Gontijo, Renata Clementino;Derchain, Sophie Fran?oise Mauricette;Nakano, Fabiana Yumi;Teixeira, Julio César;Martinez, Edson Zangiacomi;
Revista Brasileira de Ginecologia e Obstetrícia , 2002, DOI: 10.1590/S0100-72032002000100006
Abstract: purpose: to determine the factors associated with the detection of a microinvasive carcinoma in the cervical cone of women with a previous colposcopically directed biopsy compatible with cervical intraepithelial neoplasia (cin) 3 and to evaluate the proportion of involved margins. patients and methods: we reviewed the medical records of 385 women (mean age: 39 years) submitted to cold conization or conization by high frequency surgery (hfs) with a loop during the period from january 1993 to july 2000. these procedures were indicated on the basis of a biopsy compatible with (cin) 3. results: the diagnosis of the cone was compatible with (cin) 3 in 243 (63%) women and with (cin) 2 in 13 (3%). only 10 presented hpv/cin 1 (3%) and eight had no residual disease in the cone. however, 101 (26%) women presented a microinvasive carcinoma in the cone and 10 (3%) presented a frankly invasive carcinoma. age, menstrual status and number of deliveries were not related to the severity of the cone lesion. women with oncologic colpocytology changes suggestive of invasion presented a significantly higher risk of having a microinvasive or invasive carcinoma as determined by final histology (p<0.01), although 52 of the 243 women with cin 2 or cin 3 in the cone also showed a suggestion of invasion at colpocytology. among the women with cin 2 or 3, the epithelium was white in 44%, dotted in 21%, and mosaic-like in 17%. this proportion was similar for women with a microinvasive or invasive carcinoma, with these images being detected in 37%, 23% and 21% of the cases, respectively. involvement of the cone margins was significantly higher among women submitted to hfs (49%) than among those submitted to cold conization (29%). conclusion: the absence of independent clinical and colposcopic factors associated with the detection of a microinvasive carcinoma in women submitted to conization on the basis of a biopsy compatible with (cin) 3 justifies the conical excision of the squamocolumnar junct
Detec??o do DNA do papilomavírus humano após excis?o da zona de transforma??o com al?a diatérmica para tratamento de neoplasia intra-epitelial cervical
Figueirêdo, Priscila Garcia;Derchain, Sophie Fran?oise Mauricette;Sarian, Luis Otávio Zanatta;Gontijo, Renata Clementino;Andrade, Liliana Aparecida De ?ngelo;Campos, Elizabete Aparecida;Martinez, Edson Zangiacomi;
Revista Brasileira de Ginecologia e Obstetrícia , 2003, DOI: 10.1590/S0100-72032003000100002
Abstract: purpose: to evaluate the detection of high oncogenic risk human papillomavirus dna (hpv-dna) immediately before and 4±1.25 months after large loop excision of the transformation zone (lletz) in the treatment of cervical intraepithelial neoplasia (cin). methods: in this clinical prospective study, 78 patients submitted to lletz from february to december 2001 were enrolled. all patients were submitted to colposcopic evaluation and had pap smear and hybrid capture ii (hc ii) specimens collected immediately before lletz and four months after the procedure. statistical analysis was made through odds ratio (or) calculations with 95% confidence interval (95% ci). results: before excision, 67 (86%) women had positive hc ii for high oncogenic risk hpv-dna, while four months afterwards only 22 (33%) maintained positive hc ii results. positive results of hpv-dna after treatment were not associated with previous viral load, compromised margins in the surgical specimen or age. four months after the procedure, detection of hpv-dna was significantly associated with cytological abnormalities (or = 4.8; ci 95%: 1.7-13.7) but not with histological residual disease or relapse (or = 6.0; ci 95%: 0.8-52.3). conclusion: hpv-dna detection was significantly reduced after treatment of cin, but was not associated with the presence of histologic residual disease or relapse.
Valor recreativo do rio Araguaia, regi o de Aruan , estimado pelo método do custo de viagem = Recreational value of the Araguaia river, Aruan region, as estimated by the travel cost method
Priscila Garcia Angelo,Adriana Rosa Carvalho
Acta Scientiarum : Biological Sciences , 2007,
Abstract: O método do custo de viagem, que permite estimar o valor econ mico de um ambiente natural por meio de seu uso para a recrea o, foi utilizado para estimar o valor recreativo do rio Araguaia, regi o de Aruan , por meio de entrevistas com os turistas que freqüentam a regi o sazonalmente em julho de cada ano. As informa es de julho/2005indicam que os custos incorridos na viagem s o influenciados pela distancia viajada e pela freqüência anual de visitas. O rio atrai um turismo baseado na natureza, sendo que os visitantes preferem apreciar e utilizar o rio enquanto pescam, bebem ou descansam. Emboraa maioria n o tenha conhecimento de processos ecológicos e n o saiba o que é planície inundável, mais da metade considera-se usuária dos recursos do rio, em especial a água e o peixe. O valor recreativo do rio Araguaia estimado pelos gastos incorridos por este públicofoi de R$ 17 bilh es ano-1, que embora subestimado em parte pela imprecis o no registro do número anual de visitantes, é alto e confirma a importancia de investimentos ambientais que propiciem o conhecimento e manuten o da integridade ecológica do rio Araguaia e da atividade econ mica de turismo que ele sustenta. The travel cost method was used to estimate the economic value of the Araguaia river, in the Aruan region, through interviews carried outwith tourists who seasonally visit the region every year in July. Information from July/2005 indicates that the travel cost is influenced by the distance and annual frequency of visits. The river attracts nature-based tourism, in which visitors go to Aruan to appreciate and use the river while fishing, drinking and relaxing. Although most respondents have no knowledge about ecological processes and do not know what a floodplain is, more than halfof tourists consider themselves as users of the river’s resources, particularly the water and fish. The recreational value of the Araguaia river estimated throughout tourists’ expenses is R$ 17 billion year-1. Despite this value having been underestimated by the inaccuracy in the registered number of annual tourists, it is nevertheless high, and highlights the importance that environmental investments be made to promote knowledge and maintain the ecologicalintegrity of the Araguaia river, as well as to maintain the economic activity of tourism, which the ecosystem supports.
Invas?o linfática clinicamente n?o detectável do cancer vulvar
Sarian, Luís Otávio Zanatta;Marshall, Priscila Silva;Derchain, Sophie Fran?oise Mauricette;Torres, José Carlos Campos;Santos, Adriana de Cassia Paiva;Souza, Gustavo Ant?nio de;
Revista da Associa??o Médica Brasileira , 2005, DOI: 10.1590/S0104-42302005000400020
Abstract: objective: to assess the neoplastic invasion of superficial and deep inguinal lymph nodes of women with invasive vulvar squamous carcinoma smaller than 5 centimeters with a clinically normal inguinal region. methods: the medical records of 59 women cared at the state university of campinas with invasive vulvar squamous carcinoma t1 and t2 and who presented clinically normal inguinal regions (n0) were reviewed. clinical characteristics of both tumor and patients were evaluated as well as the follow-up data. odds ratios and fisher's exact test were used to assess the correlations between the invasion of inguinal lymph nodes and tumor size, grade, relapses and clinical complications. confidence limits of 95% were used. results: age of the patients ranged from 34 to 91 years (mean 67 years), and follow-up time ranged from 3 days (peri-operatory death) to 252 months (mean 27 months). clinically, 22 (37%) women had lesions t1 lesions and 37 (63%) t2. histological analysis showed unilateral lymphatic invasion in six (10%) women and bilateral in three (5%). there was no significant association between tumor size and lymph node invasion. also, pathologic tumor size and grade were not associated with lymph node neoplastic involvement. relapses and late complications were not correlated with lymph node neoplastic invasion. conclusions: superficial and deep inguinal dissection disclosed clinically undetectable lymph node neoplastic invasion, although tumor size and histological grade, relapses and late complications were not associated with node involvement.
Endometriose col?nica simulando cancer colorretal: relato de dois casos
Garcia, Ademar;Spadoni Neto, Bruno;Garcia, Victor Cezar Sano;Arruda, Priscila;Garcia, Daniela Laila;
Revista Brasileira de Coloproctologia , 2006, DOI: 10.1590/S0101-98802006000300012
Abstract: the endometriosis is an enigmatic pathology that has an uncertain etiology and is characterized by ectopic implant of functional endometrial tissue. its most common clinical presentation is periodic abdominal pain associated with menstrual period, infertility, and complaints of dyspareunie and dysmenorrheal, but its presentation can also varies, simulating colorectal tumors by presenting symptoms like tenesm and rectal bleeding. the diagnoses is made by the anatomopathologic exam and mostly explained after surgical resection. the treatment can be done clinically or surgically, depending on the age, desire to have children and the development of endometrial lesion in the gastrointestinal tract. the aim of this work is relating two cases of colonic endometriosis simulating colorectal cancer, diagnosed at the surgical service of the hospital geral universitário de cuiabá, and dissertating about the pathology forms and its treatment.
Magnetita para fixa??o de compostos tóxicos solubilizados de resíduos de fundi??o de chumbo
Godoi, Evelyn Loures de;Garcia, Priscila Moreira Peres;Ortiz, Nilce;
Engenharia Sanitaria e Ambiental , 2007, DOI: 10.1590/S1413-41522007000300014
Abstract: metallurgic waste mainly composed by magnetite (fe3o4) was studied to be used as adsorber material to fix the metallic ions present as leached and solubilizated products of smelting plant residues deposited at the decommissioned plant called panelas, located at the ribeira de iguape river basin. the adsorption beds prepared with magnetite, bentonite and ashes (mbc) show 71,4 % of removal percentage for lead ions and 26,9% for zinc ions added in similar initial concentrations with those found for solubilized and leached products, measured from smelting solid residues. the obtained adsorption velocities were similar with those found in the literature for non conventional adsorbers and the equations proposed for the empirical model shows correspondence with the experimental values.
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