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Search Results: 1 - 10 of 192401 matches for " Prabhakar D. Moses "
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The psychometric properties of Beck Depression Inventory for adolescent depression in a primary-care paediatric setting in India
Basker Mona,Moses Prabhakar D,Russell Sushila,Russell Paul
Child and Adolescent Psychiatry and Mental Health , 2007, DOI: 10.1186/1753-2000-1-8
Abstract: Background There is increasing interest in identifying adolescents with depression in primary care settings by paediatricians in India. This article studied the diagnostic accuracy, reliability and validity of Beck Depression Inventory (BDI) while used by paediatricians in a primary care setting in India. Methods 181 adolescents attending 3 schools were administered a back translated Tamil version of BDI by a paediatrician to evaluate its psychometric properties along with Children's Depression Rating Scale (CDRS-R) for convergent validity. Clinical diagnosis of depressive disorders, for reference standard, was based on ICD-10 interview by an independent psychiatrist who also administered the Impact of Event Scale (IES) for divergent validity. Appropriate analyses for validity and diagnostic accuracy both at the item and scale levels were conducted. Results A cut-off score of ≥ 5 (Sn = 90.9%, Sp = 17.6 %) for screening and cut-off score of ≥ 22 (Sn = 27.3%, Sp = 90%) for diagnostic utility is suggested. The 4 week test – retest reliability was good (r = 0.82). In addition to the adequate face and content validity, BDI has very good internal consistency (α = 0.96), high convergent validity with CDRS-R (r = 0.72; P = 0.001), and high discriminant validity with IES (r = 0.26; P = 0.23). There was a moderate concordance rate with the reference standard (54.5%) in identifying depression among the adolescents. Factor analysis replicated the 2-factor structure explaining 30.5 % of variance. Conclusion The BDI proved to be a psychometrically sound measure for use by paediatricians in a primary care setting in India. The possibility of screening for depressive disorders through the use of BDI may be helpful in identifying probable cases of the disorder among adolescents.
Isolated tongue involvement-An unusual presentation of Wilson′s disease
Kumar T,Moses Prabhakar
Journal of Postgraduate Medicine , 2005,
Griscelli syndrome
Kumar T,Ebenazar Sam,Moses Prabhakar
Indian Journal of Dermatology , 2006,
Abstract: Partial albinism with immunodeficiency is a rare and fatal immunologic disorder characterized by pigmentary dilution and variable cellular immunodeficiency. It was initially described in 1978. Primary abnormalities included silvery grayish sheen to the hair, large pigment agglomerations in hair shafts and an abundance of mature melanosomes in melanocytes, with reduced pigmentation of adjacent keratinocytes. We describe a child with Griscelli syndrome who presented with hepatitis, pancytopenia and silvery hair. The diagnosis was confirmed by microscopic skin and hair examination.
Estimation of the Burden of Pandemic(H1N1)2009 in Developing Countries: Experience from a Tertiary Care Center in South India
Mahesh Moorthy, Prasanna Samuel, John Victor Peter, Saranya Vijayakumar, Dipika Sekhar, Valsan P. Verghese, Indira Agarwal, Prabhakar D. Moses, Kala Ebenezer, Ooriapadickal Cherian Abraham, Kurien Thomas, Prasad Mathews, Akhilesh C. Mishra, Renu Lal, Jayaprakash Muliyil, Asha Mary Abraham
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0041507
Abstract: Background The burden of the pandemic (H1N1) 2009 influenza might be underestimated if detection of the virus is mandated to diagnose infection. Using an alternate approach, we propose that a much higher pandemic burden was experienced in our institution. Methodology/Principal Findings Consecutive patients (n = 2588) presenting to our hospital with influenza like illness (ILI) or severe acute respiratory infection (SARI) during a 1-year period (May 2009–April 2010) were prospectively recruited and tested for influenza A by real-time RT-PCR. Analysis of weekly trends showed an 11-fold increase in patients presenting with ILI/SARI during the peak pandemic period when compared with the pre-pandemic period and a significant (P<0.001) increase in SARI admissions during the pandemic period (30±15.9 admissions/week) when compared with pre-pandemic (7±2.5) and post-pandemic periods (5±3.8). However, Influenza A was detected in less than one-third of patients with ILI/SARI [699 (27.0%)]; a majority of these (557/699, 79.7%) were Pandemic (H1N1)2009 virus [A/H1N1/09]. An A/H1N1/09 positive test was correlated with shorter symptom duration prior to presentation (p = 0.03). More ILI cases tested positive for A/H1N1/09 when compared with SARI (27.4% vs. 14.6%, P = 0.037). When the entire study population was considered, A/H1N1/09 positivity was associated with lower risk of hospitalization (p<0.0001) and ICU admission (p = 0.013) suggesting mild self-limiting illness in a majority. Conclusion/Significance Analysis of weekly trends of ILI/SARI suggest a higher burden of the pandemic attributable to A/H1N1/09 than estimates assessed by a positive PCR test alone. The study highlights methodological consideration in the estimation of burden of pandemic influenza in developing countries using hospital-based data that may help assess the impact of future outbreaks of respiratory illnesses.
Paraneoplastic papilloedema in a child with neuroblastoma
Scott Julius,Moses Prabhakar,Somashekar H,Sathish Kumar T
Indian Journal of Cancer , 2005,
Abstract: Non-metastatic neurological disease complicating neuroblastoma is well recognized. Gross papilloedema in the absence of intracranial disease as initial manifestation of neuroblastoma is reported in adults. We report for the first time a case of bilateral papilloedema in a child with neuroblastoma in the absence of intracranial disease and hypertension.
Amikacin-induced type 5 Bartter-like syndrome with severe hypocalcemia
Chrispal A,Boorugu H,Prabhakar A,Moses V
Journal of Postgraduate Medicine , 2009,
Abstract: Aminoglycoside-induced renal toxicity is well known and may manifest with nonoliguric renal failure or renal tubular dysfunction. Aminoglycoside-induced renal tubular dysfunction could result in diffuse damage or manifest as a Fanconi-like syndrome, Bartter-like syndrome, or distal renal tubular acidosis. We discuss a patient who developed severe renal tubular dysfunction secondary to short-term therapy with Amikacin, resulting in refractory hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, and polyuria. This constellation of biochemical abnormalities mimic Type 5 Bartter′s syndrome, where there is activating mutation of the calcium sensing receptor in the thick ascending loop of Henle and the distal tubule. In this case this activation of the calcium sensing receptor was triggered by amikacin. This phenomenon has been described with gentamicin though never with amikacin. Recovery of the tubular dysfunction took 15 days following cessation of the offending drug, Amikacin.
Uncommon Headaches
Prabhakar S,Khurana D
Annals of Indian Academy of Neurology , 2002,
Abstract: Some headaches are relatively uncommon. They may be either primary of secondary and their recognition is dependent on the characterization of symptoms as well as identification of certain specific situations in which they need to be considered in the differential diagnosis. Primary headache syndromes like the paroxysmal hemicranias, SUNCT (short-lasting unilateral neuralgiform headache with conjunctival injection and tearing), cough headaches and hypnic headaches are uncommonly encountered in routine clinical practice. They have subtle unique features and specific therapies which differentiate them from the commoner primary headaches. Among the secondary causes, headaches may be an uncommon presenting feature of known clinical disorders, lack of awareness of which may result in significant morbidity. These disorders which may present with headache as the main symptom will be the focus of discussion in this review.
The Rainbow Group in Mae La camp
Forced Migration Review , 2013,
Abstract: Discrimination, verbal abuse and physical and sexual violence followBurmese LGBTI people who cross into Thailand to seek shelter incamps.
Impact of Reactive Power in Power Evacuation from Wind Turbines  [PDF]
Ashish Ranjan, S. Prabhakar Karthikeyan, Ankur Ahuja, K. Palanisamy, I. Jacob Raglend, D. P. Kothari
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2009, DOI: 10.4236/jemaa.2009.11004
Abstract: Application of Distributed Generation (DG) to supply the demands of a diverse customer base plays a vital role in the renewable energy environment. Various DG technologies are being integrated into power systems to provide alterna-tives to energy sources and to improve reliability of the system. Power Evacuation from these remotely located DG’s remains a major concern for the power utilities these days. The main cause of concern regarding evacuation is con-sumption of reactive power for excitation by Induction Generators (IG) used in wind power production which affects the power system in variety of ways. This paper deals with the issues related to reactive power consumption by Induc-tion generators during power evacuation. Induction generator based wind turbine model using MATLAB/SIMULINK is simulated and its impact on the grid is observed. The simulated results are analyzed and validated with the real time results for the system considered. A wind farm is also modeled and simulations are carried out to study the various im-pacts it has on the grid & nearby wind turbines during Islanding and system event especially on 3-Phase to ground fault.
Design Optimization of Cam & Follower Mechanism of an Internal Combustion Engine for Improving the Engine Efficiency  [PDF]
Mahesh R. Mali, Prabhakar D. Maskar, Shravan H. Gawande, Jay S. Bagi
Modern Mechanical Engineering (MME) , 2012, DOI: 10.4236/mme.2012.23014
Abstract: The current cam and follower mechanism in four stroke internal combustion engine employs a flat follower. In this work an attempt is made to change the flat face of follower to a curved face follower, so that the required point contact can be achieved. As line contact between existing cam and follower mechanism results in high frictional losses which results in low mechanical efficiency. It is observed that the frequency of vibration in the existing and modified cam and follower mechanism remains almost same. The finite element approach is used to perform the analysis.
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