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Search Results: 1 - 10 of 840 matches for " Ponni Narayanan "
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Study of Changes to the Organic Functional Groups of a High Volatile Bituminous Coal during Organic Acid Treatment Process by FTIR Spectroscopy  [PDF]
B. Manoj, Ponni Narayanan
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2013, DOI: 10.4236/jmmce.2013.12008
Abstract:

A high volatile bituminous coal was subjected to a series of organic acid treatment in steps using citric acid (1 hr and 2 hr) and buffered EDTA with acetic acid (1 to 3 hr) at room temperature. Leaching was performed with acetic acid (2N) also for 1 hr. Citric acid procedure reduced the mineral matter below 1.94%. Calcites and aluminates are completely removed along with substantial quantity of silicates by citric acid leaching. The change in absorption of organic functional groups and mineral matter in coal samples were studied using Fourier transform infrared spectroscopy (FTIR). Analysis indicated that oxygen containing species were decreased in the coal structure during acetic acid and citric acid (40%) procedure and buffered EDTA 3 hours leaching. As the period of leaching with buffered EDTA increased from 1 hr to 3 hr, organic functional groups and mineral functional groups decreased its intensity. The results indicated that the described acid treatment procedures with citric acid have measurable effects on the coal structure.

Aggressive approach in a case of cancer cervix with uremia
Janaki M,Mukesh S,Arul Ponni T,Nirmala S
Indian Journal of Palliative Care , 2010,
Abstract: Carcinoma of cervix is the most common cancer in developing countries. Majority of them present in locally advanced stages. A 36-year-old lady presented with bleeding and white discharge per vagina since four months, vomiting and reduced urine output since two weeks. Patient had an exophytic cervical growth. Investigation revealed elevated serum creatinine. Patient received single fraction radiation and underwent percutaneous nephrostomy. At one month follow-up, serum creatinine returned to almost normal level. Patient underwent bilateral ante grade stenting and completed concurrent chemoradiotherapy. In selected subsets of patients, aggressive management offered longer palliation and good quality of life.
Literature Review of Single Machine Scheduling Problem with Uniform Parallel Machines  [PDF]
Panneerselvam Senthilkumar, Sockalingam Narayanan
Intelligent Information Management (IIM) , 2010, DOI: 10.4236/iim.2010.28056
Abstract: This paper presents a survey of single machine scheduling problem with uniform parallel machines. The single machine scheduling problem with uniform parallel machines consists of n jobs, each with single operation, which are to be scheduled on m parallel machines with different speeds. These parallel machines are also called proportional machines or related machines. There are several measures of performance which are to be optimized in uniform parallel machines scheduling. Since, this scheduling problem is a combinatorial problem; usage of a heuristic is inevitable to obtain solution in polynomial time. This paper gives a classification of the literatures of this scheduling problem in three major categories, viz. offline scheduling, online scheduling and miscellaneous scheduling. In total, the available literatures are classified into 17 subgroups. Under each of the first two categories, the available literatures are discussed under different groups based on different measures of performance and non-preemptive/preemptive nature of the jobs. In the last category, the literatures are discussed under three subgroups, namely non-preemptive jobs, preemptive jobs and periodic jobs.
Simulated Annealing Algorithm to Minimize Makespanin Single Machine Scheduling Problem withUniform Parallel Machines  [PDF]
Panneerselvam Senthilkumar, Sockalingam Narayanan
Intelligent Information Management (IIM) , 2011, DOI: 10.4236/iim.2011.31003
Abstract: This paper presents a simulated annealing algorithm to minimize makespan of single machine scheduling problem with uniform parallel machines. The single machine scheduling problem with uniform parallel machines consists of n jobs, each with single operation, which are to be scheduled on m parallel machines with different speeds. Since, this scheduling problem is a combinatorial problem; usage of a heuristic is inevitable to obtain the solution in polynomial time. In this paper, simulated annealing algorithm is presented. In the first phase, a seed generation algorithm is given. Then, it is followed by three variations of the simulated annealing algorithms and their comparison using ANOVA in terms of their solutions on makespan.
GA Based Heuristic to Minimize Makespan in Single Machine Scheduling Problem with Uniform Parallel Machines  [PDF]
P. Senthilkumar, S. Narayanan
Intelligent Information Management (IIM) , 2011, DOI: 10.4236/iim.2011.35025
Abstract: This paper considers the single machine scheduling problem with uniform parallel machines in which the objective is to minimize the makespan. Four different GA based heuristics are designed by taking different combinations of crossover methods, viz. single point crossover method and two point crossover method, and job allocation methods while generating initial population, viz. equal number of jobs allocation to machines and proportionate number of jobs allocation to machines based on machine speeds. A detailed experiment has been conducted by assuming three factors, viz. Problem size, crossover method and job allocation method on 135 problem sizes each with two replications generated randomly. Finally, it is suggested to use the GA based heuristic with single point crossover method, in which the proportionate number of jobs allocated to machines based on machine speeds.
Production of Phosphate-Rich Biofertiliser Using Vermicompost and Anaerobic Digestor Sludge—A Case Study  [PDF]
C. M. Narayanan
Advances in Chemical Engineering and Science (ACES) , 2012, DOI: 10.4236/aces.2012.22022
Abstract: This paper presents the technology and cost effectiveness of production of phosphate rich biofertiliser (called PROM) by bioconversion of phosphate rock ore into soluble phosphates (that are directly assimilable by plants) in presence of an organic manure such as Vermicompost or anaerobic digestor sludge (discharged from biogas manufacturing units) and using a microbial culture of Bacillus megatherium var phosphaticum. PROM has been found to be an excellent, less expensive, substitute to synthetic phosphatic fertilisers such as SSP, MAP and DAP. This is based on real—life field trials. It is also possible to integrate the production of PROM, with biogas generation and the layout of such a more profitable, integrated scheme is also presented in this paper.
Enhancing Lab Source Anomalous Scattering Using Cr Kα Radiation for Its Potential Application in Determining Macromolecular Structures  [PDF]
Sibi Narayanan, Devadasan Velmurugan
Crystal Structure Theory and Applications (CSTA) , 2012, DOI: 10.4236/csta.2012.13016
Abstract: Obtaining phase information for the solution of macromolecular structures is a bottleneck in X-ray crystallography. Anomalous dispersion was recognized as a powerful tool for phasing macromolecular structures. It was used mainly to supplement the isomorphous replacement or to locate the anomalous scatterer itself. The first step in solving macromolecular structures by SAD (single-wavelength anomalous diffraction) is the location of the anomalous scatterers. The SAD method for experimental phasing has evolved substantially in the recent years. A phasing tool, 5-amino-2,4,6- triiodoisophthalic acid (I3C—magic triangle), was incorporated into three proteins, lysozyme, glucose isomerase and thermolysin using quick-soaking and co-crystallization method in order to understand the binding of metal ion with proteins. The high quality of the diffraction data, the use of chromium anode X-ray radiation and the required amount of anomalous signal enabled way for successful structure determination and automated model building. An analysis and/or comparison of the sulfur and iodine anomalous signals at the Cr Kα wavelength are discussed.
Ce-SAD Phasing of Glucose Isomerase and Thermolysin Using Cu Radiation  [PDF]
Sibi Narayanan, Devadasan Velmurugan
Crystal Structure Theory and Applications (CSTA) , 2013, DOI: 10.4236/csta.2013.23013
Abstract:

Current structural genomics projects aim to solve a large number of selected protein structures as fast as possible. High degree of automation and standardization is required at every step of the whole process to speed up protein structure determination. Phase problem is a bottleneck in macromolecular structure determination and also in model building which is a time-consuming task. The simplest approach to phasing macromolecular crystal structures is the use of a SAD signal. SAD data can be collected using the in-house copper (1.54 A) wavelength source. Data collected using copper wavelength with the incorporation of anomalously scattering heavy metal atoms may serve as a powerful tool for structural biologists to solve novel protein structures as well where synchrotron beam line is not available. A short soak of protein crystals in heavy metal solution or by incorporating heavy atoms into the protein drop while crystallizing the protein (co-crystallization) leads to incorporation of these heavy metal ions into the ordered solvent shell around the protein surface. The present work aims to determine whether cerium ion can be successfully incorporated into the protein crystal through quick-soaking method while maintaining the isomorphism. The study also aims in understanding whether this metal ion can be used for phasing purpose. The intensity data are collected and analyzed for anomalous signal, substructure solution and the binding sites.

Lab Source Anomalous Scattering Using Cr Kα Radiation  [PDF]
Sibi Narayanan, Devadasan Velmurugan
Crystal Structure Theory and Applications (CSTA) , 2013, DOI: 10.4236/csta.2013.22008
Abstract: High-throughput crystallography requires a method by which the structures of proteins can be determined quickly and easily. Experimental phasing is an essential technique in determining the three-dimensional protein structures using single-crystal X-ray diffraction. In macromolecular crystallography, the phases are derived either by Molecular Replacement (MR) method using the atomic coordinates of a structurally similar protein or by locating the positions of heavy atoms that are intrinsic to the protein or that have been added (MIR, MIRAS, SIR, SIRAS, MAD and SAD). Availability of in-house lab data collection sources (Cu and Cr radiation), cryo-crystallography and improved software for heavy atom location and density modification have increased the ability to solve protein structures using SAD. SAD phasing using intrinsic anomalous scatterers like sulfur, chlorine, calcium, manganese and zinc, which are already present in the protein becomes increasingly attractive owing to the advanced phasing methods. An analysis of successful SAD phasing on three proteins, lysozyme, glucose isomerase and thermolysin based on the signal of weak anomalous scatterers such as sulfur atom and chloride ion have been carried out. This analysis also proves that even the anomalous signal provided or present naturally in a macromolecule is good enough to solve crystal structures successfully using lab source chromium-generated X-ray radiation.
Analytical Solutions of Nonlinear Differential Equations in the Mathematical Model for Inactivation of Nitric Oxide by Rat Cerebellar Slices  [PDF]
Narayanan Mehala, Lakshmanan Rajendran
American Journal of Analytical Chemistry (AJAC) , 2014, DOI: 10.4236/ajac.2014.514099
Abstract: A mathematical model for the inactivation of nitric oxide by rat cerebellar slices under non-steady state condition has been analyzed. This diffusion-inactivation model was used to estimate the kinetics of NO consumption by the rat cerebellar slices. He’s Homotopy perturbation method is used to solve the first order nonlinear differential equations which describe the concentrations given by net of diffusion and inactivation by the slices. Analytical expressions for the concentration of nitric oxide have been derived for all values of parameters. The obtained analytical results are compared with the simulation results (Matlab/Scilab program) and are found to be in good agreement.
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