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Search Results: 1 - 10 of 57297 matches for " Po-Cheng Huang "
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The association between online gaming, social phobia, and depression: an internet survey
Han-Ting Wei, Mu-Hong Chen, Po-Cheng Huang, Ya-Mei Bai
BMC Psychiatry , 2012, DOI: 10.1186/1471-244x-12-92
Abstract: An online questionnaire was designed and posted on a popular online game websites, inviting the online gamers to participate the survey. The content of the questionnaire included demographic data, profiles of internet usage and online gaming, and self-rating scales of Depression and Somatic Symptoms Scale (DSSS), Social Phobia Inventory (SPIN), and Chen Internet Addiction Scale (CIAS).A total of 722 online gamers with a mean age of 21.8?±?4.9?years completed the online survey within one month. 601 (83.2%) participants were male, and 121 (16.8%) were female. The mean weekly online gaming time was 28.2?±?19.7 hours, which positively associated with history of online gaming (r?=?0.245, p?<?0.001), total DSSS (r?=?0.210, p?<?0.001), SPIN (r?=?0.150, p?<?0.001), and CIAS (r?=?0.290, p?<?0.001) scores. The female players had a shorter history of online gaming (6.0?±?3.1 vs. 7.2?±?3.6?years, p?=?0.001) and shorter weekly online gaming hours (23.2?±?17.0 vs. 29.2?±?20.2 hours, p?=?0.002), but had higher DSSS (13.0?±?9.3 vs. 10.9?±?9.7, p?=?0.032) and SPIN (22.8?±?14.3 vs. 19.6?±?13.5, p?=?0.019) scores than the male players. The linear regression model showed that higher DSSS scores were associated with female gender, higher SPIN scores, higher CIAS scores, and longer weekly online gaming hours, with controlling for age and years of education.The online gamers with longer weekly gaming hours tended to have a longer history of online gaming, and more severe depressive, social phobic, and internet addiction symptoms. Female online gamers had fewer weekly online gaming hours and a shorter previous online gaming history, but tended to have more severe somatic, pain, and social phobic symptoms. The predictors for depression were higher social phobic symptom, higher internet addiction symptoms, longer online gaming hours, and female gender.In recent years, internet addiction has been regarded as an increasingly significant public health issue. A range of studies have demonstrated
Complications of Cement-Augmented Dynamic Hip Screws in Unstable Type Intertrochanteric Fractures - A Case Series Study
Meng-Huang Wu,Po-Cheng Lee,Kuo-Ti Peng,Chi-Chuan Wu
Chang Gung Medical Journal , 2012,
Abstract: Background: Polymethylmethacrylate (PMMA) cement-augmented dynamic hip screws (DHS) have been used as a solution in unstable intertrochanteric fractures (ITF). Our aim was to investigate the complications in PMMA cement-augmented DHS.Methods: All patients who had received DHS plate osteosynthesis with or without PMMA cement augmentation from August 2005 to July 2009 in one medical center were retrospectively reviewed. The fractures were classified as unstable (31-A2.2, 31-A2.3 and 31-A3) on the basis of the Arbeitsgemeinschaft für Osteosynthesefragen classification. Inclusion criteria were patients older than 75 years, unstable ITF treated with cement-augmented DHS, and a minimum of 12 months of follow-up. Exclusion criteria were stable ITFs, incomplete chart records and imaging studies, loss to follow-up or death before bone union.Results: Three hundred twenty-one patients received DHS during the study period. Sixty-seven patients were included in the study (25 men and 42 women; mean age, 81.2 years). The mean follow-up time was 40.2 months, and the mean union time was 18.5 weeks (12-40 weeks). No patient had a lag screw cut-out. Six patients had delayed union or nonunion with side plate failures, including side plate breakage in 1 patient, screw breakage in 3, screw pullout in 1, and recurrent side plate breakage and screw breakage in 1. Deep infection occurred in 1 patient, and 1 had osteonecrosis at the femoral head. The procedure-related complication rate was 8.9%.Conclusions:Cement-augmented DHS have a different failure mode than screw cutout in conventional DHS. Failures tended to be more related to delayed union, nonunion and resultant side plate construct failure.
Food Supplement 20070721-GX May Increase CD34+ Stem Cells and Telomerase Activity
Po-Cheng Lin,Tzyy-Wen Chiou,Po-Yen Liu,Shee-Ping Chen,Hsin-I Wang,Pi-Chun Huang,Shinn-Zong Lin,Horng-Jyh Harn
Journal of Biomedicine and Biotechnology , 2012, DOI: 10.1155/2012/498051
Abstract: Few rejuvenation and antiaging markers are used to evaluate food supplements. We measured three markers in peripheral blood to evaluate the antiaging effects of a food supplement containing placental extract. Samples were evaluated for CD34
Sun Tracking Systems: A Review
Chia-Yen Lee,Po-Cheng Chou,Che-Ming Chiang,Chiu-Feng Lin
Sensors , 2009, DOI: 10.3390/s90503875
Abstract: The output power produced by high-concentration solar thermal and photovoltaic systems is directly related to the amount of solar energy acquired by the system, and it is therefore necessary to track the sun’s position with a high degree of accuracy. Many systems have been proposed to facilitate this task over the past 20 years. Accordingly, this paper commences by providing a high level overview of the sun tracking system field and then describes some of the more significant proposals for closed-loop and open-loop types of sun tracking systems.
Ipsilateral Femoral Neck and Shaft Fractures Treated with Russell-Taylor Reconstruction Intramedullary Nails
Hsuan-Kai Kao,Chi-Chuan Wu,Po-Cheng Lee,Chun-Yi Su
Chang Gung Medical Journal , 2006,
Abstract: Background: Ipsilateral femoral neck and shaft fractures are rare injuries and the treatmentis complicated and versatile. No single device has been considered absolutelysuperior to others.Methods: Fifteen combined fractures in 15 patients were treated with Russell-Taylorreconstruction intramedullary nails (recon nails). Twelve surgeries were performedwithin 24 hours of trauma and the other 3 were delayed for 4-7 daysdue to associated life-threatening injuries. Postoperatively, protected weightbearing was permitted as early as possible.Results: The median operating time was 250 minutes (range 125-430 min) and medianblood loss was 300 ml (range 100-600 ml). Thirteen patients were followed-up for a median of 22 months (range 13-45 months). The union ratesfor neck and shaft fractures were 84.6% and 69.2% respectively. The medianunion times were 3.0 months for neck fractures and 8.5 months for shaftfractures.Conclusions: Recon nails are alternative acceptable devices to treat combined fractures.However, the stability of neck fixation may be insufficient and restriction ofvigorous activity is suggested to avoid fixation failure.
Bridge-Plating Osteosynthesis of 20 Comminuted Subtrochanteric Fractures with Dynamic Hip Screw
Shang-won Yu,Po-Cheng Lee,Pang-Hsin Hsieh,Juin-Yih Su
Chang Gung Medical Journal , 2002,
Abstract: Background: A prospective clinical trial was conducted to evaluate the conjunctive use ofan extramedullary device and the bridge-plating technique in the treatment ofcomminuted subtrochanteric fractures with major extension into the femoralshaft.Methods: A Winquist criteria was used to classify 3 fracture patterns. The type 3 fractureswere excluded from this study because of great extent of the fracturezone for which the bridge-plating technique is not indicated. There were 14men and 6 women, with a mean age of 49 (range, 17-76) years. A dynamichip screw (DHS) with a long side plate was chosen as the fixation devicebecause of the small learning curve.Results: The fractures united at a mean of 7.6 (range, 3-15) months postoperatively.Mobility was scored at 9 points in 18 patients and 6 points in 2 patients(Mobility score of Parker & Palmer). Pain was absent in 14, mild in 3, andmoderate in 3 patients. Two limbs were shortened by 1 and 1.5 cm, respectively.Conclusion: Our results indicate that DHS fixation using the bridge-plating techniqueleads to union of all comminuted Winquist types 1 and 2 fractures withoutmajor complications, and it is a valuable alternative to new intramedullarydevices. This procedure offers the significant advantage of being less technicallydemanding.
Primary Total Hip Arthroplasty without the Use of Bone Cement: A 10-Year Follow-up of 157 Hips
Pang-Hsin Hsieh,Chun-Hsiung Shih,Po-Cheng Lee,Chih-Hwa Chen
Chang Gung Medical Journal , 2002,
Abstract: Background: The cementless fixation technique in total hip arthroplasty (THA) was developedto solve clinical problems such as aseptic loosening and osteolysiswhich were thought to be associated with the use of bone cement. This retrospectivestudy reports our mid-term results with cementless THA.Methods: A series of 173 consecutive, unselected cementless THA procedures usingthe Omnifit prosthesis was performed by a single surgeon. Sixteen hips wereexcluded from the study because of insufficient follow-up evaluation. Onehundred and fifty-seven THAs with an average follow-up period of 10.2(range, 5-12) years were retrospectively reviewed.Results: The overall revision rate was 7.0%. Ninety-five percent of unrevised hipsachieved a Merle D'Aubigne hip score of 16 points or above.Radiographically, bone ingrowth occurred in all unrevised cups, and in 95%of unrevised stems. Osteolytic lesions, seen on 28.1% of femora and 8.9% ofpelvises, appeared at an average of 3.8 years postoperatively. Femoral osteolyticlesions were confined to the proximal Gruen zones 1 and 7. The meanannual polyethylene wear rate was 0.15 mm. Approximately 1/3 of the hipswere noted to have excessive wear.Conclusion: These results suggest that cementless Omnifit THA provides stable fixationfor as long as 12 years after implantation. Of significant concern is the highincidence of excessive polyethylene wear and associated osteolysis. Ourexperience also indicates that a femoral stem with a circumferential porouscoating in the proximal region can protect the femur from distal osteolysis.
Enhanced Sensing Characteristics in MEMS-based Formaldehyde Gas Sensor
Yu-Hsiang Wang,C. -C. Hsiao,Chia-Yen Lee,R. -H. Ma,Po-Cheng Chou
Computer Science , 2008,
Abstract: This study has successfully demonstrated a novel self-heating formaldehyde gas sensor based on a thin film of NiO sensing layer. A new fabrication process has been developed in which the Pt micro heater and electrodes are deposited directly on the substrate and the NiO thin film is deposited above on the micro heater to serve as sensing layer. Pt electrodes are formed below the sensing layer to measure the electrical conductivity changes caused by formaldehyde oxidation at the oxide surface. Furthermore, the upper sensing layer and NiO/Al2O3 co-sputtering significantly increases the sensitivity of the gas sensor, improves its detection limit capability. The microfabricated formaldehyde gas sensor presented in this study is suitable not only for industrial process monitoring, but also for the detection of formaldehyde concentrations in buildings in order to safeguard human health.
Amiodarone Inhibits Apamin-Sensitive Potassium Currents
Isik Turker, Chih-Chieh Yu, Po-Cheng Chang, Zhenhui Chen, Yoshiro Sohma, Shien-Fong Lin, Peng-Sheng Chen, Tomohiko Ai
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0070450
Abstract: Background Apamin sensitive potassium current (IKAS), carried by the type 2 small conductance Ca2+-activated potassium (SK2) channels, plays an important role in post-shock action potential duration (APD) shortening and recurrent spontaneous ventricular fibrillation (VF) in failing ventricles. Objective To test the hypothesis that amiodarone inhibits IKAS in human embryonic kidney 293 (HEK-293) cells. Methods We used the patch-clamp technique to study IKAS in HEK-293 cells transiently expressing human SK2 before and after amiodarone administration. Results Amiodarone inhibited IKAS in a dose-dependent manner (IC50, 2.67±0.25 μM with 1 μM intrapipette Ca2+). Maximal inhibition was observed with 50 μM amiodarone which inhibited 85.6±3.1% of IKAS induced with 1 μM intrapipette Ca2+ (n = 3). IKAS inhibition by amiodarone was not voltage-dependent, but was Ca2+-dependent: 30 μM amiodarone inhibited 81.5±1.9% of IKAS induced with 1 μM Ca2+ (n = 4), and 16.4±4.9% with 250 nM Ca2+ (n = 5). Desethylamiodarone, a major metabolite of amiodarone, also exerts voltage-independent but Ca2+ dependent inhibition of IKAS. Conclusion Both amiodarone and desethylamiodarone inhibit IKAS at therapeutic concentrations. The inhibition is independent of time and voltage, but is dependent on the intracellular Ca2+ concentration. SK2 current inhibition may in part underlie amiodarone's effects in preventing electrical storm in failing ventricles.
A Meta-Analysis of Mortality in End-Stage Renal Disease Patients Receiving Implantable Cardioverter Defibrillators (ICDs)
Tien-Hsing Chen, Hung-Ta Wo, Po-Cheng Chang, Chun-Chieh Wang, Ming-Shien Wen, Chung-Chuan Chou
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0099418
Abstract: Data on the effectiveness of implantable implantable cardioverter defibrillators (ICDs) with respect to reducing mortality in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) are lacking. The purpose of this meta-analysis was to compare the mortality of patients with ESRD who have received and not received an ICD. A search was conducted on January 31, 2013 of Medline, Cochrane, EMBASE, and Google Scholar. Studies were selected for inclusion based on the following criteria. 1) Randomized controlled trial. 2) ESRD patients with heart failure. 3) Device therapy (ICD, CRT-defibrillator [CRT-D]) used to treat heart failure. 4) Primary outcome is survival analysis. 5) Retrospective study if survival analysis was performed. The primary outcome was overall survival (OS), and the secondary outcome was 2-year survival. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated, and a χ2-based test of homogeneity was performed. Three studies were included in the analysis. The combined OR for OS was 2.245 (95% CI 1.871 to 2.685, P<0.001), indicating that patients with an ICD had a significantly higher OS than those without an ICD. The combined OR for 2-year survival was 2.312 (95% CI 1.921 to 2.784, P<0.001), indicating that patients with an ICD had a significantly higher 2-year survival rate than those without an ICD. The use of ICD in patients with ESRD is associated with an increase in the OS and the 2-year survival rate.
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