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Search Results: 1 - 10 of 5910 matches for " Pinhua Rao "
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Hydrothermal Carbonization of Nonylphenol Ethoxylates Waste Liquid for Energy Source Generation  [PDF]
Yongquan Ge, Wenqi Zhang, Gang Xue, Pinhua Rao
American Journal of Analytical Chemistry (AJAC) , 2015, DOI: 10.4236/ajac.2015.613101
Abstract: Nonylphenol polyethoxylates (NPEOs) are widely used as nonionic surfactants in many industry fields. High concentration NPEOs waste water is produced in some production processes. It is often treated to realize reduction by distillation. Therefore, NPEOs waste liquid with higher concentration is produced and it is difficult to be treated by traditional water treatment process. In this study, hydrothermal carbonization process was used to convert NPEOs waste liquid to carbonaceous product (hydrochar) with sulfuric acid as additive in 24 h at 200°C. The hydrochar was characterized by scanning electron microscope, Fourier-transform infrared spectrometer and thermogravimetric analysis. The element composition and the high heat value of the hydrochar were similar to lignite, showing that it could be used as an alternative fuel.
Synthesis of CuOx/MnO2 Heterostructures with Enhanced Visible Light-Driven Photocatalytic Activity  [PDF]
Tao Yu, Yangang Sun, Cui Zhe, Wei Wang, Pinhua Rao
Journal of Materials Science and Chemical Engineering (MSCE) , 2017, DOI: 10.4236/msce.2017.510002
Abstract: Organic pollutants coming from various industry processes are harmful to the environment, and semiconductor heterostructure is a promising candidate catalyst for poisonous wastewater treatment in the future. In this study, CuOx/MnO2 heterostructures were successfully constructed, using a facile and effective hydrothermal method and chemical both/calcination route, which exhibited higher photocatalytic activity towards the photodegradation of organic contaminants under visible-light driven irradiation. The resulting CuOx/MnO2 heterostructures were systematically characterized using various microscopic and spectroscopic techniques. Morphological characterizations show that the CuOx nanoparticles are well anchored on the surface of the MnO2 nanowires (NMs). The photocatalytic activity enhancement of the CuOx/MnO2 heterostructures (M-4) could be ascribed to the introduction of CuOx on the surface of MnO2 NWs and the efficient separation of the electron-hole pairs compared to other CuOx/MnO2 heterostructures and pure MnO2 NMs. These results show that CuOx/MnO2 heterostructures can be a suitable candidate for efficient visible light photocatalysts.
Compare of three ways of synthesis of simple Schiff base
Zhaoqi Yang,Pinhua Sun
Molbank , 2006, DOI: 10.3390/m514
Abstract: No abstract available
Synthesis of 1-benzyl-3-chloro-4-(3,4,5-trimethoxyphenyl)azetidin-2-one
Zhaoqi Yang,Pinhua Sun
Molbank , 2006, DOI: 10.3390/m513
Abstract: No abstract available
Clinical Efficacy of Allergen Specific Immunotherapy (ASIT) in Allergic Rhinitis  [PDF]
Rao Sukhesh
International Journal of Clinical Medicine (IJCM) , 2011, DOI: 10.4236/ijcm.2011.24066
Abstract: Though efficacy of Allergen Specific Immunotherapy (ASIT) has been proved in many studies, reports about success in clinical practice and under field conditions in alleviating the suffering or decreasing the morbidity in patients of Allergic Rhinitis are few. 260 patients of Allergic Rhinitis without coexisting diseases were included. Skin prick test was done on all patients. ASIT was initiated with common inhalant indoor allergens as per standard protocol and patients were assessed at the start and at 2 m, 6 m and 18 months of ASIT. ASIT was able to significantly reduce the symptom score in all the three groups namely sneezing, rhinorrhoea and nasal itching (p < 0.001). Concurrently it was also able to produce a significant reduction in the usage of concomitant drug intake (p < 0.001) thereby implying a decrease in morbidity. When assessed regarding clinical efficacy, ASIT was found to be satisfactory or highly effective in more than 75% patients. ASIT has got a role in clinical practice in polysensitized patients in field conditions. This is based on the evidence that besides decrease in hypersensitivity/symptoms, it also has an effect on minimizing the necessity of taking drugs to relieve the symptoms, which has strong implications of economics and toxicity, while treating patients.
Going beyond Computation and Its Limits: Injecting Cognition into Computing  [PDF]
Rao Mikkilineni
Applied Mathematics (AM) , 2012, DOI: 10.4236/am.2012.331248
Abstract: Cognition is the ability to process information, apply knowledge, and change the circumstance. Cognition is associated with intent and its accomplishment through various processes that monitor and control a system and its environment. Cognition is associated with a sense of “self” (the observer) and the systems with which it interacts (the environment or the “observed”). Cognition extensively uses time and history in executing and regulating tasks that constitute a cognitive process. Whether cognition is computation in the strict sense of adhering to Turing-Church thesis or needs additional constructs is a very relevant question for addressing the design of self-managing (autonomous) distributed computing systems. In this paper we argue that cognition requires more than mere book-keeping provided by the Turing machines and certain aspects of cognition such as self-identity, self-description, self-monitoring and self-management can be implemented using parallel extensions to current serial von-Neumann stored program control (SPC) Turing machine implementations. We argue that the new DIME (Distributed Intelligent Computing Element) computing model, recently introduced as the building block of the DIME network architecture, is an analogue of Turing’s O-machine and extends it to implement a recursive managed distributed computing network, which can be viewed as an interconnected group of such specialized Oracle machines, referred to as a DIME network. The DIME network architecture provides the architectural resiliency, which is often associated with cellular organisms, through auto-failover; auto-scaling; live-migration; and end-to-end transaction security assurance in a distributed system. We argue that the self-identity and self-management processes of a DIME network inject the elements of cognition into Turing machine based computing as is demonstrated by two prototypes eliminating the complexity introduced by hypervisors, virtual machines and other layers of ad-hoc management software in today’s distributed computing environments.
Effect of Brucea javanica oil emulsion on proliferation, migration and autophagy of non-small cell lung cancer A549 cells and the underlying mechanisms

ZHU Xiangliang
, PAN Pinhua

- , 2018, DOI: 10.11817/j.issn.1672-7347.2018.11.006
Increased oxidative stress and altered antioxidants status in patients with chronic allergic rhinitis  [PDF]
Shiefa Sequeira, Ashalatha V. Rao, Anjali Rao
Advances in Bioscience and Biotechnology (ABB) , 2012, DOI: 10.4236/abb.2012.327117
Abstract: Background: Allergic rhinitis is an inflammatory disorder of the upper airways. Although several oxidants and antioxidants are likely to be involved, alterations in only limited parameters have been studied. Objective: In this study an attempt has been made to study the oxidant-antioxidant imbalance by investigating changes in a wide range of oxidants and antioxidants in the blood. Methods: Blood samples were obtained from 39 chronic allergic rhinitis patients (males 24, females 15), aged 20-70 (mean age 36.33 ± 2.03) years and 53 individuals (36 males, 17 females); aged 24 to 64 (mean age 45.42 ± 1.36) years. Duration of allergic rhinitis was 1.77 ± 0.237 years. In the study group, nasal symptoms were scored and the results were recorded. The patients were classified as having perennial Allergic rhinitis (PAR) if they had had at least 2 rhinitis symptoms (sneezing, rhinorrhea, nasal obstruction, itching) for at least 6 months a year in the previous 2 years and if they had a positive skin prick test response to at least 1 clinically significant perennial allergen (e.g., house dust mites, molds, cockroach, cockroach excrement grass and tree pollen, cat and dog epithelia and molds, or animal dander). They had no other allergic diseases except persistent allergic rhinitis diagnosed by the physical and history examination. Erythrocyte lipid peroxidation, erythrocyte antioxidants viz., glutathione, glutathione reductase, superoxide dismutase, catalase and plasma antioxidants viz., ceruloplasmin, glutathione-S-transferase, vitamin C, total antioxidant activity were estimated in the above two groups. Results: Erythrocyte lipid peroxidation (0 hour, p < 0.01) and superoxide dismutase (p < 0.01) were significantly higher, whereas plasma vitamin C (p < 0.001), ceruloplasmin (p < 0.05) and total antioxidant activity (p < 0.001) were significantly lower in chronic allergic rhinitis patients when compared to controls. Plasma Glutathione S transferase and erythrocyte catalase, glutathione, and glutathione reductase remained unchanged from normal subjects. Conclusion: The changes in different parameters indicate an imbalance in the oxidant and antioxidant status in chronic allergic rhinitis patients. Further studies are required to investigate the potential for antioxidant supplements to be used as routine therapy in chronic allergic rhinitis patients. Capsule summery: The study shows that the body is trying to cope for the oxidative stress by altering the enzyme levels. But external supplement may also be required as the total antioxidant levels are
A Validated Stability-Indicating UHPLC Method for Determination of Naproxen and Its Related Compounds in Bulk Drug Samples  [PDF]
K. Tirumala Rao, L. Vaikunta Rao
American Journal of Analytical Chemistry (AJAC) , 2013, DOI: 10.4236/ajac.2013.46036

A simple, rapid, precise, accurate, rugged and robust stability-indicating ultra-fast high performance liquid chromatographic (UHPLC) method has been developed for the estimation of related compounds (imp-A, imp-B, imp-C, imp-D and imp-E) in Naproxen and also the assay of Naproxen from bulk drug samples. The stability indicating capability of the method was proven by subjecting the samples to stress conditions such as acid, base, oxidation, photolysis and thermal degradation. The efficient chromatographic separation was achieved using mobile phase solution A prepared as buffer solution 10 mM monobasic potassium phosphate pH 4.0 ± 0.05 adjusted with diluted ortho phosphoric acid solution and solution B acetonitrile with linear gradient elution on poroshell 120 EC-C18 shot column (50 mm × 4.6 mm, 2.7 μm) and UV detection at 235 nm at a flow rate 1.0 mL/min, column oven temperature was set to 25?C. The above are all known impurities and degradation impurities are well resolved with Naproxen peak and these are eluted within a 10 min runtime of HPLC. The photo diode array detector was used for peak homogeneity testing during stress study experiments and the overall mass balance was found to be 99.2% to 100.2% in all stress conditions. The linear calibration range was found to be 0.05 μg/mL to 0.75 μg/mL for related compounds and 50 μg/mL to 150 μg/mL for Naproxen and the accuracy of the method was found to be 91.5% to 98.5% recovery for the related substance method and 95.4% to 97.4% recovery for the assay method. The Naproxen and related compounds were found to be stable up to 48 hours and the method validation data show excellent results for precision, linearity, specificity, limit of detection, limit of quantitation and robustness. The present method can be successfully used for routine QC and stability studies and it will help to

Identification of structurally and functionally significant deleterious nsSNPs of GSS gene: in silico analysis  [PDF]
Ramavartheni Kanthappan, Rao Sethumadhavan
Advances in Bioscience and Biotechnology (ABB) , 2010, DOI: 10.4236/abb.2010.14048
Abstract: It is becoming more and more apparent that most genetic disorders are caused by biochemical abnormalities. Recent advances in human genome project and related research have showed us to detect and understand most of the inborn errors of metabolism. These are often caused by point mutations manifested as single-nucleotide-polymorphisms (SNPs). The GSS gene inquested in this work was analyzed for potential mutations with the help of computational tools like SIFT, PolyPhen and UTRscan. It was noted that 84.38% nsSNPs were found to be deleterious by the sequence homology based tool (SIFT), 78.13% by the structure homology based tool (PolyPhen) and 75% by both the SIFT and PolyPhen servers. Two major mutations occurred in the native protein (2HGS) coded by GSS gene at positions R125C and R236Q. Then a modeled structure for the mutant proteins (R125C and R236Q) was proposed and compared with that of the native protein. It was found that the total energy of the mutant (R125C and R236Q) proteins were -31893.846 and -31833.818 Kcal/mol respectively and that of the native protein was -31977.365 Kcal/mol. Also the RMSD values between the native and mutant (R125C and R236Q) type proteins were 1.80Å and 1.54Å. Hence, we conclude based on our study that the above mutations could be the major target mutations in causing the glutathione synthetase deficiency.
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