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Search Results: 1 - 10 of 3125 matches for " Philomène Kouna Ndouongo "
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Frequency of Distal Sensory Polyneuropathy among Diabetics in Parakou in 2012  [PDF]
Adoukonou Thierry, Kouna-Ndouongo Philomène, Sourokou Boni Justine, Imorou Abdoulaye, Houinato Dismand
Neuroscience & Medicine (NM) , 2015, DOI: 10.4236/nm.2015.63016
Abstract: Background: The distal sensory polyneuropathy (DSP) was more frequent among diabetics, although its determinant was not well known among diabetics in Benin. Objective: We aimed to assess the frequency of DSP and its determinants among diabetics at Parakou. Methods: It was a cross-sectional study carried out from 1 March to 31 August 2012 and included 336 diabetics followed at the diabetes unit of Parakou hospital. The diagnosis of DSP was based on DNS (Diabetic Neuropathy Score) criteria and other criteria. All data concerning the diabetes mellitus were recorded. We used Epi-Info and SPSS 16.0 software to perform analysis. Results: They were 187 females (56.0%) with the mean age of 54.9 ± 10.9 years. 298 patients fulfilled criteria for DSP; the overall prevalence of DSP was 88.7%. The main associated factors in multivariate analysis were treatment duration of diabetes more than 4 years: OR = 36.7 [4.0 - 336.9]; the elevated glycaemia: OR = 3.1 [1.4 - 7.1]; the activity with high income: OR = 0.2 [0.0 - 0.8]; the ethnicity: nagots/fon: OR: 3.7 [1.4 - 12.5]. Conclusion: Those results suggested the high frequency of DSP among diabetics at Parakou.
A Case of Multiple Sclerosis to Gabon: Myth or Reality!  [PDF]
Ibrahima Aissata Camara, Lansana Laho Diallo, Philomène Kouna Ndouongo
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105592
Introduction: Multiple sclerosis is a neuro-inflammatory demyelinating disease rare in Africa south of the Sahara. Objective: The objective of this work is to describe multiple sclerosis in African black women from Gabon and to list the principles of care. Observation: We report the case of a Gab-onese girl, 21 years old, with no particular history, who had multiple scle-rosis following a decrease in visual acuity for six months associated with tingling and motor deficit of the lower right limb. Protein electrophoresis and cerebral magnetic resonance imaging (MRI) advocated multiple sclerosis. Conclusion: This observation highlights the fact that multiple sclerosis is a rare condition in black African countries and its discovery must always be considered as a diagnosis of elimination.
Distal Sensory Polyneuropathy among HIV Patients in Libreville in Gabon  [PDF]
Kouna-Ndouongo Philomène, Adoukonou Thierry, Oura Landry, Ibole James, Assengone-Zeh Yvonne, Moubeka Mounguengui Martine, Mouangue Minso Gertrude
Neuroscience & Medicine (NM) , 2015, DOI: 10.4236/nm.2015.63015
Abstract: Distal sensory polyneuropathy (DSP) was more frequent among Human Immunodeficiency Virus (HIV) patients. The reliable tool for its diagnosis is not available everywhere in sub-Saharan Africa. We aimed to estimate the frequency of DSP among HIV patients in Libreville. We’ve conducted a cross-sectional study including all consecutives HIV-patients admitted to the HIV clinic in the University Teaching Hospital of Libreville (Gabon) between 1 May and 31 July 2014. All patients underwent a full neurological examination doing by two neurologists. The diagnosis of DSP was based on Brief Peripheral Neuropathy Screen (BPNS). We also collected the data concerning past medical history, the use of neurotoxic drug, history of disease and data of High Active Antiretroviral Therapy (HAART). The logistic regression was used to study the factors associated with DSP. They were 620 patients aged from 17 to 74 years with the mean age of 42.1 years ± 11.0 years and 570 (91.9%) were on HAART. The mean duration of disease was 57.6 ± 42.5 months. Among the 620 patients 170 fulfilled criteria for DSP, and the overall frequency of DSP was 27.4%. The associated factors in univariate analysis were the age, the occupation, the use of HAART, the HAART option, the stage of the disease, opportunistic disease, alcohol consumption, exposure to isoniazid, diabetes mellitus and the modes of contamination. But in multivariate analysis the associated factors were the stage of disease OR 2.7 [1.2 - 3.7], diabetes mellitus OR 2.4 [1.4 - 5.8] and the use of D4T in HAART OR 1.9 [1.1 - 4.9]. The main symptoms among the patients were burning feet (47.6%), the tingling (40.0%), numbness (27.6%), alteration of ankle reflex (87.6%) and alteration of vibration sensation (27.6%). The DSP was more frequent among HIV patients and could be explained by the duration of the disease, the association with metabolic disease and the use of D4T.
Secondary Bithalamic Ischemic Vascular Accident Has an Occlusion of the Artery of Percheron  [PDF]
Jennifer Nyangui Mapaga, Ibrahima A?ssata Camara, Grass Aurelle Mambila Matsalou, Pupchen Marilyse Gnigone, Nelly Diouf Mbourou, Annick Nsounda Mandzela, Cherif Mohamadou Aidara, Kouna Ndouongo Philomène
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105169
The bithalamic ischemic stroke secondary to percheron artery occlusion occupies a small place in the large ischemic stroke family, but its clinical polymorphism arouses patrician curiosity. We thus report 3 observations that explain the richness of this affection.
Prevalence of migraine among university students at Parakou, Benin: A cross-sectional study  [PDF]
Thierry Adoukonou, Francis Tognon-Tchegnonsi, Kouna Philomène, Abdias Alabi, Dismand Houinato, Pierre-Marie Preux
World Journal of Neuroscience (WJNS) , 2014, DOI: 10.4236/wjns.2014.41003

Objective: To determine the prevalence of migraine and its associated factors in students at the University of Parakou. Methods: It was a cross-sectional study carried out from February 1st to April 30th 2011. It included all students registered during the academic year 2010-2011 and selected by systematic random sampling. Migraine was defined according to IHS 2004 criteria. To assess the link between migraine and body mass index we collected height and weight of each student. Multivariate analysis was used to study the factors associated with migraine, odds-ratio and their confidence interval were estimated. SPSS Soft-ware was used to perform statistical analysis. Results: During the study period 1200, students returned their questionnaires. They were 842 males and 358 females. 171 fulfilled migraine criteria, and the overall prevalence of migraine was 14.2% (CI 95%: 11.6% - 17.4%). The main associated factors were the sex with an OR: 2.3 (CI 95%: 1.6 - 3.2) and family history of headache with an OR: 1.6 (CI 95%: 1.1 - 2.4). Migraine with aura was the frequent form (59.1%) and visual aura the frequent form of aura. No association was found between migraine and body mass index but students with obesity had high risk of migraine with aura OR: 3.8 (CI 95%: 1.5 - 9.7) compared with those with normal weight. The main triggering factors were sleeplessness (90.1%) and mental fatigue (85.4%). Conclusion: The results suggest a high prevalence of migraine among students at Parakou University and no association between obesity and migraine.

Determinants of Neurocognitive Impairment in HIV in a Cohort of Patients on Antiretroviral Therapy Followed in Bangui (Central African Republic)  [PDF]
Mbelesso Pascal, Tekpa Gaspard, Ndouongou--Kouna Philomène, Yangatimbi Emmanuel, Amakade--Woyengba Phrygie Avilah, Honisse Hortense
Neuroscience & Medicine (NM) , 2016, DOI: 10.4236/nm.2016.71001
Abstract: Infection with HIV is one of the deadliest epidemics of our time and its type is widespread in the Central African Republic. It is frequently accompanied by neurological complications. Objective: To contribute to a better understanding of neurocognitive disorders in patients living with HIV (PLHIV) in Bangui, and to identify associated factors using the International HIV Dementia Scale (IHDS) as a screening tool. We conducted a descriptive and analytical cross-sectional study from 1 December 2014 to 30 January 2015, in a cohort of patients seen on one of the supported sites in Bangui. A total of 400 patients were received in follow-up visit during the study period of which 244 met the inclusion criteria. The prevalence of neurocognitive disorders was 25%, 95% CI [19.70 - 30.92]. The mean age of subjects was 42.77 ± 9.58 with extremes ranging from 24 - 64 years. The sex ratio (F/M) was 4.5 in. The average score for different tests was 10.93 ± 1.13 with extremes of 7 and 12. The disorder was more about the gestural sequence. Determinants of neurocognitive disorders in the cohort were older age and lower educational level (p < 0.05). It is useful to conduct further studies to confirm these results by combining a battery of neuropsychological tests to recommend this test for all the support sites of PLHIV in the country.
High-Field MRI Contribution in Tolosa-Hunt Syndrome (THS). Report of Two Cases and Review of Literature  [PDF]
Chérif Mohamadou Aidara, Philomène Kouna, Jennifer Nyangui Mapaga, Nfally Badji, Hamidou Deme, Abdoulaye Dione Diop, Abdoulaye Ndoye Diop, Sokhna Ba, El Hadj Niang
Open Journal of Radiology (OJRad) , 2018, DOI: 10.4236/ojrad.2018.83016
Abstract: Background: Tolosa Hunt Syndrome is an inflammatory condition of unknown etiology of the cavernous sinus and superior orbital fissure. Because of the difficulty in establishing histological evidence, his diagnosis is based on a set of arguments established by the International Headache Society. MRI allows indirect visualization of the granuloma and plays a key role in diagnosis and follow-up. Aim: To illustrate High-field MRI contribution in Tolosa-Hunt Syndrome (THS). Cases Presentation: Two patients, a 25-year-old female and a 40-year-old male were recruited in this retrospective case report study at the Radiology service of Fann University Hospital (Dakar Senegal). The first patient has been suffering from a right retro-orbital pain and diplopia for 2 months and the second from a painful oculomotor nerve palsy for 3 months. Blood tests, lumbar puncture, thyroid hormone levels and an infectious screen were done. Screening for converting enzymes, and serum antibodies were also done. They underwent a high field MRI (Siemens 1.5T) with T1, T2, FLAIR, T2*, diffusion B1000, TOF polygon, CISS 3D and T1 gadolinium sequences in the 3 planes space. No significant abnormality was detected in blood tests or CSF analysis. Screening for converting enzymes and serum antibodies screen were also negative. For each patient, MRI examinations showed a non tumoral thickening of the right cavernous sinus, suggesting a granulomatous involvement. Tolosa Hunt Syndrome was evoked firstly. They were put on corticotherapy at high doses with a spectacular regression of symptoms. The Criteria of the International Headache Society of THS were met in both patients. Conclusion: High-field MRI is a significant diagnostic tool in the assessment of painful ophthalmoplegia. It allows a direct visualization of the granuloma of the cavernous sinus and assesses its course throughout the disease.
Stroke Epidemiology in Douala: Three Years Prospective Study in a Teaching Hospital in Cameroon  [PDF]
Yacouba N. Mapoure, C. Kuate, Clet B. Tchaleu, Hugo B. Mbatchou Ngahane, Gérard N. Mounjouopou, Hamadou Ba, Salomon Mbahe, Julius Y. Fonsah, Gérard Beyiha, Henry N. Luma, Albert S. Mouelle, Philomène K. Ndouongo, Alfred K. Njamnshi
World Journal of Neuroscience (WJNS) , 2014, DOI: 10.4236/wjns.2014.45044
Abstract: Background and Objectives: Cerebro-vascular accident or stroke constitutes a major challenge in sub-Saharan Africa. In Cameroon, basic epidemiologic data are not routinely available. Aims: The aim of this study was to determine the type, the associated risk factors, time to admission, the clinical presentation and the case fatality of stroke at the Douala General Hospital (DGH) in Cameroon. Methods: A cross-sectional study was performed from January 1, 2010 to December 31, 2012 at the neurology and intensive care units of the DGH. All patients above 15 years of age with a diagnosis of established stroke were enrolled. For each patient, socio-demographic, clinical and paraclinical data were recorded as well as the duration of hospitalization and the case fatality. Results: In all, 325 patients were enrolled with males constituting 68.1% and general mean age of 58.66 ± 13.6 years. The mean initial consultation delay was 47.36 ± 18.48 hours. The majors cerebro-vascular risk factors were hypertension (81.15%), chronic alcohol consumption (28.3%), diabetes mellitus (20.61%), obesity (18.15%), cigarette smoking (16%), dyslipidemia (8.9%) and atrial fibrillation (3.07%). Ischemic stroke accounted for 52% of cases while 48% were hemorrhagic. The mean duration of hospitalization was 8.58 ± 6.35 days with a case fatality rate of 26.8%. Septic conditions appeared to be the leading cause of death accounting for 35.6% of cases. Conclusion: Stroke in the DGH is associated with a high case fatality rate and hypertension remains the number one risk factor. There is a clear and urgent need for public health authorities to reinforce measures for the control of modifiable stroke risk factors.
Prevalence and Associated Factors of Cephales in a Professional Environment—Case of Teachers of Libreville  [PDF]
Ibrahima Aissata Camara, Maёl Ndao Eteno, Annick Nsounda Mandzela, Nelly Diouf Mbourou, Grass Aurelle Mambila Matsalou, Jennifer Nyangui Mapaga, Pupchen Marilyse Gnigone, Landry Oura, Mounguengui Martine Moubecka, Philomène Kouna
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105168
Objective: To determine the prevalence of headaches among Libreville teachers. Introduction: Headaches, commonly referred to as “headaches”, correspond to all the unpleasant sensations felt in the head. It is generally a question of subjective manifestations that only the patient can express. The most common functional sign is pain, which in itself is difficult to measure. Methodology: This is a cross-sectional prospective study with analytical and descriptive aims, which took place over a period of 4 months from February 1st to June 1st, 2016. It took place in five public secondary schools in two of the six districts of Libreville. Was considered cephalalgic (or suffering from headache), any teacher who answered “Yes” to the question: “Are you prone to headaches?” The choice of the reference interval to be able to evaluate the working time of the recruited teachers was inspired by the European standards which globally place the average weekly working time of teachers between 30 and 40 hours. The collected data were processed and analyzed with Epi-info 7 and SPSS 22 software. A regression analysis was performed to identify the associated factors. Results: We collected 236 teachers whose average age was 43.2 ± 7.9 years, with extremes of 27 and 60 years. There were 141 men (59.7%) and 95 women (40.3%) with a sex ratio of 0.96. The prevalence of headache was 76.7%. The factors associated with headaches were the subject taught, the number of students, and the provision of private tutoring. Five main triggers were found: overwork (86.2%), lack of sleep (84.5%), sun (73.5%), noise (68%) and fatigue (64.6%). The effects of headache were discomfort in daily activities (65.7%), absenteeism (35.9%) and a reduction in sleep time. Conclusion: Our study shows that headaches particularly affect the teaching profession with female predominance due to stressful situations caused by their work environment.
Slow Spinal Cord Compression Inducing by Malignant Peripheral Nerve Sheath Tumors in Cotonou  [PDF]
D. Gnonlonfoun, C. Adjien, J. Nyangui Mapaga, L. Hode, G. Goudjinou, A. Sowanou, R. Domingo, P. Gnigone, G. Mambila, D. Affanou, P. H. Kouna Ndouongo, D. Houinato
Neuroscience & Medicine (NM) , 2018, DOI: 10.4236/nm.2018.91004
Abstract: MPNST is a very uncommon malignant type of neoplasm. It is often associated with neurofibromatosis type 1 (von Recklinghausen disease). It involves large anatomical regions, and thus takes on varied clinical presentations. However, bone location of MPNST, particularly in the spinal canal has been poorly described in the literature. We hereby report the case of a 29-year old young man with MPNST in the spinal canal. He presented a slow spinal cord compression confirmed by spinal MRI. MPNST was revealed through histologic and immune histochemical features after tumor resection.
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