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Search Results: 1 - 10 of 17861 matches for " Pedro;Macedo "
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Alterations in Retinoic Acid Receptors in Non-Small Cell Lung Cancer and Their Clinical Implications  [PDF]
Saé Mu?iz-Hernández, Norma Hernández-Pedro, Omar E. Macedo-Pérez, Oscar Arrieta
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.68072
Abstract: The nuclear retinoic acid receptor may play a critical role in the process of lung carcinogenesis. Alteration or loss of nuclear retinoic acid receptors (RARs) has been associated with progression in premalignant and malignant tissues and it is associated with malignant transformation in human cells. Vitamin A derivates, such as retinoic acid, have emerged as adjuvant to therapy in several types of cancer with favorable effects. Retinoic acid regulates the expression of target genes through the binding and activation of RARs, inhibiting growth proliferation. Diverse studies have evaluated different retinoids alone or in combination with chemotherapy in lung cancer, from which results have been controversial with benefits observed only in the subpopulation with high levels of triglycerides. Additionally, several large randomized trials using retinoids to prevent tobacco-related cancer have failed; due to the latter the use of retinoids in clinical trials remains controversial. However they could reduce the risk of cancer development in non-smokers. There is evidence that retinoids have different effects on lung cancer; still the identification of biomarkers could determinate their benefits as preventive or therapy agents. This review describes the RAR alterations during the development of Non-Small Cell Lung Cancer and sets out the importance of several cancer treatments with retinoid compounds.
Balan?o de energia em vinhedo de 'Niagara Rosada'
Pezzopane, José Ricardo Macedo;Pedro Júnior, Mário José;
Bragantia , 2003, DOI: 10.1590/S0006-87052003000100019
Abstract: the energy balance method was used to characterize the hourly variation of the net radiation, latent and sensible fluxes and soil heat flux on a mature vineyard grown at jundiaí, s?o paulo, brazil. the grapevines, cv. niagara rosada, in the vineyard were wrapped to trellis wires, creating compact hedgerows 2 m apart, 1.7 m height and 0.4 wide, with the foliage 1m above the soil surface. also, the net and incoming radiation relationships and the partioning of the available energy to the system into latent and heat flux, and soil heat flux were determined for the vineyard. during a sunny day (dry period) the latent heat flux was 44% of the net radiation and the sensible heat flux, 48%. however during a rainy day, the latent heat flux was 86% of the net radiation and the sensible heat flux, 21%. during a sunny day, after the occurrence of rain, the latent and sensible heat fluxes were, respectively, 68% and 29% of the net radiation. the soil heat flux was 5.7 an 1.3% of the net radiation, for bare soil and mulched rows, respectively.
Balan o de energia em vinhedo de 'Niagara Rosada'
Pezzopane José Ricardo Macedo,Pedro Júnior Mário José
Bragantia , 2003,
Abstract: O método do balan o de energia foi utilizado para caracterizar a varia o horária do saldo de radia o e dos fluxos de calor latente, sensível e no solo, em vinhedo cultivado com a cultivar NiagaraRosada', conduzida no sistema de espaldeira, em Jundiaí (SP). Além disso, foram determinadas as rela es entre o saldo de radia o (SR) no vinhedo e a radia o solar global (RG) e a parti o da energia disponível ao sistema nos fluxos de calor latente (LE), sensível (H) e no solo (G). Em um dia característico de período seco, o LE representou 44% do SR e o H, 48%. Em um dia chuvoso, o LE representou 86% do SR e o H, 21%. Em um dia ensolarado, após um período de chuvas, LE e H foram, respectivamente, 68% e 29% do SR. O G foi, em média, 5,7% e 1,3% do SR para as ruas mantidas capinadas e com forro, respectivamente.
Perfil epidemiológico do trauma de face dos pacientes atendidos no pronto socorro de um hospital público
Macedo, Jefferson Lessa Soares de;Camargo, Larissa Macedo de;Almeida, Pedro Fragoso de;Rosa, Simone Corrêa;
Revista do Colégio Brasileiro de Cirurgi?es , 2008, DOI: 10.1590/S0100-69912008000100004
Abstract: background: to evaluate the etiology, age, gender and location of the lesions of facial trauma in patients arriving at our hospital. methods: the data were evaluated through retrospective analysis of patient charts from january 1st to december 31st, 2004. results: the group comprised 711 patients with facial trauma. blunt assault was the most common cause, followed by motor vehicle crashes. falls were, by far, the predominant cause of injury in children, but with increasing age, assaults became more common. it was observed a male:female ratio of 3:1. the most frequent age group was the 21-30 years one, with 52%. facial fractures were found in 24.9% of facial injuries. the most frequent fracture was nasal (76.8%). conclusion: aggressions or interpersonal violence were the main cause of facial trauma in our population. the causes of facial trauma were directly related to the age.
An Enhanced Reservation-Based MAC Protocol for IEEE 802.15.4 Networks
José A. Afonso,Helder D. Silva,Pedro Macedo,Luis A. Rocha
Sensors , 2011, DOI: 10.3390/s110403852
Abstract: The IEEE 802.15.4 Medium Access Control (MAC) protocol is an enabling standard for wireless sensor networks. In order to support applications requiring dedicated bandwidth or bounded delay, it provides a reservation-based scheme named Guaranteed Time Slot (GTS). However, the GTS scheme presents some drawbacks, such as inefficient bandwidth utilization and support to a maximum of only seven devices. This paper presents eLPRT (enhanced Low Power Real Time), a new reservation-based MAC protocol that introduces several performance enhancing features in comparison to the GTS scheme. This MAC protocol builds on top of LPRT (Low Power Real Time) and includes various mechanisms designed to increase data transmission reliability against channel errors, improve bandwidth utilization and increase the number of supported devices. A motion capture system based on inertial and magnetic sensors has been used to validate the protocol. The effectiveness of the performance enhancements introduced by each of the new features is demonstrated through the provision of both simulation and experimental results.
Radia??o solar e saldo de radia??o em cultivo de café a pleno sol e consorciado com banana 'Prata An?
Pezzopane, José Ricardo Macedo;Pedro Júnior, Mário José;Gallo, Paulo Boller;
Bragantia , 2005, DOI: 10.1590/S0006-87052005000300019
Abstract: microclimatic measurements (incoming solar radiation and net radiation) were taken from october, 2001 to september, 2002 in a coffee crop (coffea arabica l.) cv. icatu vermelho iac 4045, shaded by banana plants (musa aab) 'prata an? ' and unshaded at mococa, s?o paulo state, brazil (21o 28' s, 47o 01' w, altitude 665 m), aiming at evaluating the reduction of the solar and net radiation for the different crop conditions. the obtained results showed differences for the different crop conditions. the banana plants reduced the incoming solar radiation to the coffee crop by 21%, with monthly variation from 16% to 27%. differences were also found concerning the reduction of the incoming solar radiation in different points of the shaded crop. the net radiation was reduced by 16% in the daily values in the shaded plants in comparisom to the unshaded ones. the net radiation represented 50% of the incoming solar radiation in the unshaded crop, with monthly variation from 34% to 62%, and in the plots shadded by banana, the net radiation represented 53% of the incoming solar radiation, with variation from 35 to 38%.
Modifica??es microclimáticas provocadas por estufa com cobertura plástica
Pezzopane, José Eduardo Macedo;Pedro Júnior, Mário José;Ortolani, Altino Aldo;
Bragantia , 1995, DOI: 10.1590/S0006-87051995000200021
Abstract: the use of plastic greenhouse has increased in southern brazil, but the modifications in the microclimate are not well known. therefore, this research was developed at campinas, state of s?o paulo, brazil, aiming to characterize the changes in air temperature and humidity and soil temperature in a low texture plastic greenhouse. the results showed that the values of maximum air temperature were higher in the greenhouse when compared to outside and the highest values were avoided by opening the side courtines. during cool nights, mainly, with clear sky and no wind, when the temperature reached values below 10°c, the minimum air temperature values in the greenhouse were higher than the observed in the open field plot. the relative humidity, when the greenhouse was closed, showed higher values than at the open greenhouse conditions when the humidity was equal to the external conditions. also it was possible to notice that the maximum and minimum soil temperature showed higher values in the greenhouse.
Influência do sistema de condu??o no microclima, na produtividade e na qualidade de cachos da videira 'Niagara Rosada', em Jundiaí-SP
Pedro Júnior, Mário José;Hernandes, José Luiz;Tecchio, Marco Antonio;Pezzopane, José Ricardo Macedo;
Revista Brasileira de Fruticultura , 2007, DOI: 10.1590/S0100-29452007000200024
Abstract: different training systems were applied to 'niagara rosada' grapevine aiming to compare the differences in microclimate, yield and bunch quality. the grapevines were grown in the experimental farm of the instituto agron?mico at jundiaí, s?o paulo state, brazil. the 'niagara rosada' vines were grafted on iac-766 rootstock and spaced by 2x1m. two training systems were evaluated: unilateral single cordon with three vertical catch wires and double parallel cordon with sloped catch wires. measurements of transmitted solar radiation, air and bunch temperature were taken during 2005 and evaluations of: yield, leaf area index, total soluble solids and bunch weight were done during the 2004/05 and 2005/06 growing seasons. the double cordon training system showed higher values of yield, number of bunches, bunch weight and leaf area index when compared to the single cordon training system. during the analyzed period the double cordon training system showed yield values 75% higher than the single cordon. the transmitted solar radiation at harvest was lower for the double cordon training system. it was not observed statistical differences in bunch temperature and total soluble solids for the training systems.
Fatores associados à atividade física em adultos, Brasília, DF
Thomaz,Priscilla Marcondelli Dias; Costa,Teresa Helena Macedo da; Silva,Eduardo Freitas da; Hallal,Pedro Curi;
Revista de Saúde Pública , 2010, DOI: 10.1590/S0034-89102010005000027
Abstract: objective: to describe physical activity practice in adults and to identify associated factors. methods: a cross-sectional study was performed with cluster sampling from the four areas of the city of brasília, central-west brazil, in 2006-2007. a sample comprised of 469 adults was obtained from 250 randomly selected households. sociodemographic data, weight and height were obtained during a household interview. the short version of the international physical activity questionnaire (ipaq) was used to measure physical activity. a multivariate linear regression analysis was made to assess the effect of sex, body mass index (bmi), socioeconomic classification and marital status on physical activity scores. results: the majority of the sample was comprised of women (57%). the percentage of individuals who achieved 150 minutes of weekly physical activity practice was 52% (95% ci: 47; 56), while that of inactive individuals was 21.5% (95% ci: 17.8; 25.3). an inverse association between physical activity and bmi was only found in men. types of physical activity reported differed between sexes: walking and doing household chores among women; cycling, running, swimming and weight-lifting among men. there was a strong interaction between male sex and bmi in terms of the association with physical activity scores: the higher the bmi, the lower the physical activity score. conclusions: the portion of inactive individuals in brasília can be considered low, when compared to estimates from other brazilian cities. differences in bmi and physical activity score found between sexes are associated with the type of physical activity practiced.
Estado-misto: considera??es diagnósticas e terapêuticas a partir de um relato de caso
Alvarenga, Pedro Gomes de;Soares, Márcia Macedo;Issler, Cilly;Lotufo-Neto, Francisco;
Revista de Psiquiatria Clínica , 2005, DOI: 10.1590/S0101-60832005000600005
Abstract: a clinical case-report is presented to discuss the evolution of the mixed state concept and the limitations faced on its clinical management. it is emphasized the role of electroconvulsive therapy on this case. the following data were obtained by patient and family interview as well as medical notes.
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