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Search Results: 1 - 10 of 36229 matches for " Pedro Paulo Maia "
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TEIXEIRA, Pedro Paulo Maia
Nucleus Animalium , 2009,
Abstract: Death in the production of ruminant embryo is still a major obstacle, especially inprograms of IATF and recipients of embryo. In the initial stage of pregnancy, called the criticalperiod, which occurs in more than 70% of losses, this time a series of reactions occur so that there isa physiological adjustment of pregnant to not pregnant, the maternal recognition of pregnancy inwhich the concept must signal its presence by inteferon release of tau to inhibit the programmeddischarge of prostaglandin 2 alpha. The progesterone produced by the corpus luteum is one of thefactors that go down to oxytocin binds to its receptors stimulated by the action of estrogen receptorsin stimulating the production of PGF2α to cause luteolysis. The IFN-τ produced by the concept bindsto endothelial cells in the endometrium prevents the production of PGF2α and luteolysis. To improvethe rates of embryo death is necessary to make development of anti-luteolíticas, to reduce the levelsof estrogen to minimize the stimulus in OTCR, controlling the release of PGF2α, slowing or blockingthe luteolysis aumentandar or the concentration of circulating progesterone this same period.Increasing the concentration of P4, use of hCG, GnRH and ECG, are strategies to stimulate the mechanism of anti-luteolysis, and strategies involving use of specific diets among others.
Pedro Paulo Maia Teixeira,Maria Emília Franco Oliveira,Ana Carolina Moura,Victor José C. Santos
Nucleus Animalium , 2012,
Abstract: El objetivo de este experimento fue que informe técnicos rufianes, tiempo de recuperación y la influencia sobre la libido en caneros Santa Inés. Las técnicas de preparación fueron: La adherencia a la pared abdominal del pene (APAP - n = 2), estrechamiento del orificio prepucial (EOP - n = 2), la fijación de la curvatura caudal de la flexura sigmoidea (FCCFS - n = 2), y la desviación lateral pene (DLP - n = 2). Hemos utilizado los carneros de la raza Santa Inés seleccionado después de un examen clínico general del sistema reproductivo, y las pruebas de la libido. Las técnicas que se han realizado y después de 20 días de la cirugía, los animales fueron probados para la libido. El DLP fue menor el tiempo de recuperación quirúrgica, seguida de FCCFS y APPA. También se observó que el EOP no mostró fiabilidad al permitir la exposición del pene. Las técnicas no causó influencia negativa sobre el comportamiento reproductivo de los animales hasta el final del experimento.O objetivo desse experimento foi relatar técnicas de rufi es, tempo de recupera o e influência na libido em carneiros Santa Inês. As técnicas de preparo foram: Aderência do pênis à parede abdominal (APPA – n=2), Estreitamento do óstio prepucial (EOP – n=2), fixa o da curvatura caudal da flexura sigmóide (FCCFS – n=2), e desvio lateral do pênis (DLP – n=2). Foram utilizados carneiros da Ra a Santa Inês selecionados após um exame clínico geral do sistema reprodutor, além de teste de libido. As técnicas foram realizadas e após 20 dias da cirurgia, os animais foram submetidos ao teste da libido. A DLP apresentou-se menor tempo de recupera o cirúrgica, seguida pela FCCFS e APPA. Observou-se também que a EOP n o apresentou confiabilidade por permitir a exposi o do pênis. As técnicas n o promoveram influência negativa no comportamento reprodutivo dos animais até o fim do experimento.The aim of the present experiment was to report different teaser techniques, time to recover, and influence over the libido in male sheep. Four different techniques were compared: penis adherence to abdominal wall (n=2), narrowing of the prepucial ostium (n=2), fixation of the caudal sigmoid flexure (n=2), and lateral shift of the penis (n=2). Santa Inês rams were selected after general clinical and genital apparatus examination. Twenty days after surgery, animals underwent libido′s test. Surgical recovery was faster in LSP, followed by FCCSP and PAAW. NOP did not seem to be a reliable technique, once penis exposure occurred. All techniques did not play a role above breeding behavior of the animals until the completion
Pedro Paulo Maia Teixeira,Maria Emilia Franco Oliveira,Carla Cristina D'Amato,Luiz Fernando de Souza Rodrigues
Nucleus Animalium , 2011,
Abstract: O objetivo deste trabalho foi padronizar um método de ultrassonografia para exames do parênquima testicular em andrológicos de carneiros (n=6). Foi realizada biometria testicular, espermiograma e exame ultrassonográfico do parênquima testicular, realizando imagens do parênquima testicular e aferido o percentual de ecogenicidade em pela escala de cinza no próprio aparelho, correlacionando com dados da biometria e espermiograma. Verificaram-se correla es positivas entre a ecogenicidade e a concentra oespermática (p=0,0192 e r2= 0,4373) e entre ecogenicidade e motilidade massal (p=0,0358 e r2= 0,37), demonstrando que o método é eficiente para diagnosticar altera es escrotais assintomáticas aos exames convencionais, contribuindo para a reprodu o animal.The present study aimed to standardize an ultrasonogram method to testicular parenchyma in andrological sheep (n = 6). We made testicular biometric, spermiogram and testicular parenchymaultrasonography, carrying images of the testicular parenchyma and measured the percentage of the echogenicity in gray scale on the device itself, correlating with the biometrics data and spermiogram. There were positive correlations between echogenicity and sperm concentration (p = 0.0192 and r2 = 0.4373) and betweenechogenicity and mass motility (p = 0.0358 and r2 = 0.37), demonstrating that the method is efficient to detect abnormal scrotal asymptomatic by conventional tests, contributing to animal breeding.
OptFlux: an open-source software platform for in silico metabolic engineering
Isabel Rocha, Paulo Maia, Pedro Evangelista, Paulo Vila?a, Sim?o Soares, José P Pinto, Jens Nielsen, Kiran R Patil, Eugénio C Ferreira, Miguel Rocha
BMC Systems Biology , 2010, DOI: 10.1186/1752-0509-4-45
Abstract: OptFlux is an open-source and modular software aimed at being the reference computational application in the field. It is the first tool to incorporate strain optimization tasks, i.e., the identification of Metabolic Engineering targets, using Evolutionary Algorithms/Simulated Annealing metaheuristics or the previously proposed OptKnock algorithm. It also allows the use of stoichiometric metabolic models for (i) phenotype simulation of both wild-type and mutant organisms, using the methods of Flux Balance Analysis, Minimization of Metabolic Adjustment or Regulatory on/off Minimization of Metabolic flux changes, (ii) Metabolic Flux Analysis, computing the admissible flux space given a set of measured fluxes, and (iii) pathway analysis through the calculation of Elementary Flux Modes.OptFlux also contemplates several methods for model simplification and other pre-processing operations aimed at reducing the search space for optimization algorithms.The software supports importing/exporting to several flat file formats and it is compatible with the SBML standard. OptFlux has a visualization module that allows the analysis of the model structure that is compatible with the layout information of Cell Designer, allowing the superimposition of simulation results with the model graph.The OptFlux software is freely available, together with documentation and other resources, thus bridging the gap from research in strain optimization algorithms and the final users. It is a valuable platform for researchers in the field that have available a number of useful tools. Its open-source nature invites contributions by all those interested in making their methods available for the community.Given its plug-in based architecture it can be extended with new functionalities. Currently, several plug-ins are being developed, including network topology analysis tools and the integration with Boolean network based regulatory models.Metabolic Engineering (ME) deals with designing organisms with
Modelagem de fun??es no cálculo dos índices DRIS
Wadt, Paulo Guilherme Salvador;Silva, Davi José;Maia, Celsemy Eleuterio;Tomé Júnior, Juarez Barbosa;Pinto, Paulo Augusto da Costa;Machado, Pedro Luiz Oliveira de Almeida;
Pesquisa Agropecuária Brasileira , 2007, DOI: 10.1590/S0100-204X2007000100008
Abstract: the objective of this work was to model dris functions and k factor on foliar diagnosis of mango crops. ten commercial orchards, at yield stage, in the s?o francisco river valley were monitored, monthly, during a two-year period, by means of collecting leaf samples to determine n, p, k, ca, mg, b, fe, mn, zn and cu concentrations. data were tested for normality and bivariate relationships between nutrient concentrations were used to calculate dris norms. mean, variance as well as minimum and maximum values were calculated for each relationship within the population. nutrients were classified as follows: highly responsive macronutrients (hrma) (n, p and k); rarely responsive macronutrients (rrma) (ca and mg); highly responsive micronutrients (hrmi) (b, fe, mn and zn), and rarely responsive micronutrients (rrmi) (cu). dris functions were developed for each nutrient class. results showed that the developed model expresses the nutritional balance adjusted for each nutrient, and reflects the expected biological behavior of plants as a result of variation in the availability of nutrients.
Pedro Junqueira Maia
Journal of Science and Technology of the Arts , 2009, DOI: 10.7559/citarj.v1i1.10
In vitro susceptibility of Plasmodium falciparum Welch field isolates to infusions prepared from Artemisia annua L. cultivated in the Brazilian Amazon
Silva, Luiz Francisco Rocha e;Magalh?es, Pedro Melillo de;Costa, M?nica Regina Farias;Alecrim, Maria das Gra?as Costa;Chaves, Francisco Célio Maia;Hidalgo, Ari de Freitas;Pohlit, Adrian Martin;Vieira, Pedro Paulo Ribeiro;
Memórias do Instituto Oswaldo Cruz , 2012, DOI: 10.1590/S0074-02762012000700004
Abstract: artemisinin is the active antimalarial compound obtained from the leaves of artemisia annua l. artemisinin, and its semi-synthetic derivatives, are the main drugs used to treat multi-drug-resistant plasmodium falciparum (one of the human malaria parasite species). the in vitro susceptibility of p. falciparum k1 and 3d7 strains and field isolates from the state of amazonas, brazil, to a. annua infusions (5 g dry leaves in 1 l of boiling water) and the drug standards chloroquine, quinine and artemisinin were evaluated. the a. annua used was cultivated in three amazon ecosystems (várzea, terra preta de índio and terra firme) and in the city of paulínia, state of s?o paulo, brazil. artemisinin levels in the a. annua leaves used were 0.90-1.13% (m/m). the concentration of artemisinin in the infusions was 40-46 mg/l. field p. falciparum isolates were resistant to chloroquine and sensitive to quinine and artemisinin. the average 50% inhibition concentration values for a. annua infusions against field isolates were 0.11-0.14 μl/ml (these infusions exhibited artemisinin concentrations of 4.7-5.6 ng/ml) and were active in vitro against p. falciparum due to their artemisinin concentration. no synergistic effect was observed for artemisinin in the infusions.
Determinantes clínicos com influência no prognóstico da discectomia lombar: análise multifatorial
Carvalho, Paulo Jorge Da Rocha;Sá, Paulo Jorge Correia De;Freitas, Rolando Manuel Bezerra;Gon?alves, Jo?o Pedro Maia;Macedo, Sara Lemos Costa Lobo;Neves, José De Morais;
Coluna/Columna , 2010, DOI: 10.1590/S1808-18512010000100008
Abstract: inappropriate patient selection and timing for lumbar disc surgery are still the the major causes of failures. objective: we evaluated the clinical outcome and predictive factors that influence the prognosis of patients submitted to lumbar discectomy using a multivariate analysis model. methods: we report a prospective series of 68 patients with herniated lumbar disc who underwent limited discectomy during 2003 to 2007. the average follow-up period was 3.9±0.1 years. clinical findings were evaluated using japonese orthopaedic association assessment scoring system (joa=29). results: excellent and good postoperative improvement rates were obtained in 75% of the patients. male gender and preponderance of subjective symptoms over clinical signs were associated with better clinical outcomes and faster return to work. waiting time for surgery had no consistent effect on the outcome. the need for immediate surgery was questionable in the absence of significant neurological disturbance (joa for clinical signs >3/6). joa scoring had predictive value for preoperative assessment for lumbar disc surgery, i.e. preoperative joa >15 (low initial disability) correlated with poor surgery outcome. conclusions: joa scoring is easily performed for patients and clinicians, standardizes subjective data and presents high predictive value of patients' outcome after lumbar discectomy.
Scanning electron microscopy of the corneal endothelium of ostrich
Pigatto, Jo?o Antonio Tadeu;Franzen, Angela Aguiar;Pereira, Fabiana Quartiero;Almeida, Ana Carolina da Veiga Rodarte de;Laus, José Luis;Santos, Jaime Maia dos;Guedes, Pedro Mancini;Barros, Paulo Sérgio de Moraes;
Ciência Rural , 2009, DOI: 10.1590/S0103-84782009005000001
Abstract: the aim of this study was to examine the endothelial surface morphology and perform a morphometric analysis of the corneal endothelial cells of ostrich (struthio camelus) using scanning electron microscopy. polygonality, mean cell area, cell density and coefficient of variation of mean cell area were analyzed. the normal corneal endothelium consisted of polygonal cells of uniform size and shape with few interdigitations of the cell borders. microvilli appeared as protusions on the cellular surface. the average cell area was 269±18μm2 and the endothelial cell density was 3717±240cells mm-2. the coefficient of variation of the cell area was 0.06, and the percentage of hexagonal cells was 75%. the parameters evaluated did not differ significantly between the right and the left eye from the same ostrich. the results of this study showed that the ostrich corneal endothelial cells appear quite similar to those of the other vertebrates.
Acute respiratory infections in children living in two low income communities of Rio de Janeiro, Brazil
Sutmoller, Frits;Maia, Paulo Ricardo;
Memórias do Instituto Oswaldo Cruz , 1995, DOI: 10.1590/S0074-02761995000600001
Abstract: community studies of non-hospitalized children are essential to obtain a more thorough understanding of acute respiratory infections (ari) and provide important information for public health authorities. this study identified a total ari incidence rate (ir) of 4.5 per 100 child-weeks at risk and 0.78 for lower respiratory tract infections (lri). disease duration averaged less than one week and produced a total time ill with ari of 5.8% and for lri 1.2%. no clear seasonal variation was observed, the sex-specific ir showed a higher proportion of boys becoming ill with ari and lri and the peak age-specific ir occurred in infants of 6-11 months. correlation with risk factors of the child (breastfeeding, vaccination, diarrheal disease, undernourishment) and the environment (crowding, living conditions, maternal age and education) showed marginal increases in the rate ratios, making it difficult to propose clear-cuts targets for action to lower the ari and lri morbidity. the importance of an integral maternal-child health care program and public education in the early recognition of lri is discussed.
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