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Search Results: 1 - 10 of 429819 matches for " Pedro Henrique M. Braga;Fernandes "
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A mediastinoscopia no diagnóstico de doen?as intratorácicas
Júdice, Luiz Felippe;Mourad, Omar Moté Abou;Lima, Oriane Almeida Santana;Júdice, ?ngelo Mesquita;Diégues, Pedro Henrique M. Braga;Fernandes, Rodrigo Mota Pacheco;
Revista do Colégio Brasileiro de Cirurgi?es , 1998, DOI: 10.1590/S0100-69911998000100009
Abstract: the cervical mediastinoscopy, developed by carlens in 1959 is used primarily to evaluate, before thoracotomy, the status of mediastinal limph nodes in patients with lung cancer. however, exploration of the anterior mediastinum by these techniques can also identify other diseases processes such as sarcoidosis, tuberculosis, mycotic granulomatous infections and neoplastic diseases involving the mediastinum such as lymphoma. ln this study we analyze the medical reports of 125 patients in which mediastinoscopy was performed for the diagnosis of intrathoracic diseases. the procedure was performed with general anesthesia and orotracheal intubation in all patients out in two, submitted to mediastinoscopy with local anesthesia. the surgical approaches used were: cervical (n=103). anterior (n=7) and cervical + anterior (n=15). there were 80 male and 45 female patients. the age ranged from 13 to 75 years. carcinoma was the most prevalent diagnosis obtained (36.8%), followed by lymphoma (16%) and sarcoidosis (14.4%). in nine patients the exam was inconclusive, being responsible for a 7.2% failure index of the method. in eleven patients presenting superior vena cava syndrome, mediastinoscopy was performed without aditional complications, except in one case in which symptoms worsenned. we conclude that mediastinoscopy is a safe procedure and it is a valuable tool for the diagnosis of paratracheal mediastinal masses and lymphadenomegalies.
In vitro biological control of infective larvae of Ancylostoma ceylanicum Controle biológico in vitro de larvas infectantes de Ancylostoma ceylanicum
Fernanda Mara Fernandes,Jackson Victor Araújo,Fabio Ribeiro Braga,Pedro Henrique Gazzinelli-Guimar?es
Revista Brasileira de Parasitologia Veterinária , 2012, DOI: 10.1590/s1984-29612012000300018
Abstract: The aim of this study was to evaluate the predatory activity of the fungus Duddingtonia flagrans (AC001) on infective larvae of Ancylostoma ceylanicum after gastrointestinal transit in hamsters. Twenty animals were used in the experiment, divided into two groups: a treated group (10 animals) and a control group (10 animals). In the group treated with D. flagrans, each animal received mycelium from the AC001 isolate, at an oral dose of 5 mg/25 g of live weight. To evaluate the predatory activity of the fungus, fecal samples were collected from the animals in both groups, at the times of 6, 8, 12, 24 and 36 hours after the treatment. Then, subsamples of 2 g of feces were placed in Petri dishes containing 2% water-agar (2% WA) culture medium and 1000 L3 of A. ceylanicum. Over the study period, the following percentage reductions were observed: 43.2% (6 hours), 30.8% (8 hours), 25.8% (12 hours), 30% (24 hours) and 11% (36 hours). The fungus D. flagrans presented predatory activity on the L3 of A. ceylanicum, after passing through the hamsters' gastrointestinal tract. It was therefore concluded that the fungus D. flagrans may be an alternative for biological control of the L3 of A. ceylanicum. O objetivo deste trabalho foi avaliar a atividade predatória do fungo Duddingtonia flagrans (AC001) sobre larvas infectantes de Ancylostoma ceylanicum após o transito gastrintestinal em hamsters. Foram utilizados vinte animais no experimento, divididos em dois grupos: um grupo tratado (10 animais) e um grupo controle (10 animais). No grupo tratado com D. flagrans, cada animal recebeu 5mg/25g de peso vivo de micélio do isolado AC001, por via oral. Para avaliar a atividade predatória do fungo, amostras fecais foram coletadas de ambos os grupos de animais nos horários de: 6, 8, 12, 24 e 36 após o tratamento. A seguir, 2g de fezes foram colocadas em placas de Petri contendo o meio de cultura ágar-água 2% (AA2%) e 1000 L3 de A. ceylanicum. Ao longo dos horários estudados os seguintes percentuais de redu o foram observados: 43,2% (6 horas); 30,8% (8 horas); 25,8% (12 horas); 30% (24 horas) e 11% (36 horas). O fungo D. flagrans (AC001) apresentou atividade predatória sobre as L3 de A. ceylanicum após o transito pelo trato gastrintestinal de hamsters. Além disso, foi observada uma diferen a significativa nos percentuais obtidos de cada horário em rela o ao numero de L3 recuperadas (P < 0,01). Conclui-se, portanto, que o fungo D. flagrans pode ser uma alternativa de controle biológico das L3 de A. ceylanicum.
Modeled Surface Observations for Spatial Analysis of Landscape Dynamics  [PDF]
Manoel do Couto Fernandes, Tata Lacale Canal dos Santos, Pedro Henrique Ferreira Coura, Paulo Márcio Leal de Menezes, Alan José Salom?o Gra?a
Journal of Geographic Information System (JGIS) , 2013, DOI: 10.4236/jgis.2013.54039

Landscape dynamics is a geoecological characteristic that defines changes in a landscape spatial structure and function during an established time scale. In this kind of analysis, geoprocessing is an essential tool, because it combines several technologies that help in this work. However, the majority of landscape dynamic investigations do not consider the dimensionality of the data and the information to be used, which is projected not measured from modeled (real) surface observations, and presents underestimated results, mainly in irregular relief landscapes. Considering that, this paper intends to assess the difference between observations on modeled and planimetric surfaces on the interpretation of landscape dynamics. The study was conducted in the massif of Tijuca, Rio de Janeiro (Brazil) using land use and soil cover maps of different times and a digital elevation models (DEM) generated based on a triangular irregular. The results show an increase of dynamic areas values when observations were carried out on modeled surface, as well as the deforestation rate (17.57% or 0.13 km2/year). This survey showed higher values in comparison with observations on planimetric surface, characterizing more realistic interpretations of how the structural elements and analyses made from these are structured in the landscape.

Cardiac Energy Metabolism and Oxidative Stress Biomarkers in Diabetic Rat Treated with Resveratrol
Klinsmann Carolo dos Santos, Camila Pereira Braga, Pedro Octavio Barbanera, Fábio Rodrigues Ferreira Seiva, Ary Fernandes Junior, Ana Angélica Henrique Fernandes
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0102775
Abstract: Resveratrol (RSV), polyphenol from grape, was studied to evaluate its effects on calorimetric parameters, energy metabolism, and antioxidants in the myocardium of diabetic rats. The animals were randomly divided into four groups (n = 8): C (control group): normal rats; C-RSV: normal rats receiving RSV; DM: diabetic rats; and DM-RSV: diabetics rats receiving RSV. Type 1 diabetes mellitus was induced with administration of streptozotocin (STZ; 60 mg?1 body weight, single dose, i.p.). After 48 hours of STZ administration, the animals received RSV (1.0 mg/kg/day) for gavage for 30 days. Food, water, and energy intake were higher in the DM group, while administration of RSV caused decreases (p<0.05) in these parameters. The glycemia decreased and higher final body weight increased in DM-RSV when compared with the DM group. The diabetic rats showed higher serum-free fatty acid, which was normalized with RSV. Oxygen consumption (VO2) and carbon dioxide production (VCO2) decreased (p<0.05) in the DM group. This was accompanied by reductions in RQ. The C-RSV group showed higher VO2 and VCO2 values. Pyruvate dehydrogenase activity was lower in the DM group and normalizes with RSV. The DM group exhibited higher myocardial β-hydroxyacyl coenzyme-A dehydrogenase and citrate synthase activity, and RSV decreased the activity of these enzymes. The DM group had higher cardiac lactate dehydrogenase compared to the DM-RSV group. Myocardial protein carbonyl was increased in the DM group. RSV increased reduced glutathione in the cardiac tissue of diabetic animals. The glutathione reductase activity was higher in the DM-RSV group compared to the DM group. In conclusion, diabetes is accompanied by cardiac energy metabolism dysfunction and change in the biomarkers of oxidative stress. The cardioprotective effect may be mediated through RVS's ability to normalize free fatty acid oxidation, enhance utilization glucose, and control the biomarkers' level of oxidative stress under diabetic conditions.
Genetic control of soybean (Glycine max) yield in the absence and presence of the Asian rust fungus (Phakopsora pachyrhizi)
Ribeiro, Aliny Simony;Toledo, José Francisco Ferraz de;Arias, Carlos Alberto Arrabal;Godoy, Cláudia Vieira;Soares, Rafael Moreira;Moreira, José Ubirajara Vieira;Pierozzi, Pedro Henrique Braga;Vidigal, Maria Celeste Gon?alves;Oliveira, Marcelo Fernandes de;
Genetics and Molecular Biology , 2008, DOI: 10.1590/S1415-47572008000100018
Abstract: soybean is one of the most important crops in brazil and continuously generates demands for production technologies, such as cultivars resistant to diseases. in recent years, the asian rust fungus (phakopsora pachyrhizi syd. & p. syd 1914) has caused severe yield losses and the development of resistant cultivars is the best means of control. understanding the genetic control and estimating parameters associated with soybean (glycine max) resistance to p. pachyrhizi will provide essential information for cultivar selection. we investigated quantitative genetic control of p. pachyrhizi and estimated parameters associated to soybean yield in the absence and presence of this phytopathogen. six cultivars and their 15 diallel derived f2 and f3 generations were assessed in experiments carried out in the absence and presence of p. pachyrhizi. the results indicated that soybean yield in the presence and absence of p. pachyrhizi is controlled by polygenes expressing predominantly additive effects that can be selected to develop new cultivars resistant or tolerant to p. pachyrhizi. these cultivars may prove to be a useful and more durable alternative than cultivars carrying major resistance genes.
New soybean (Glycine max Fabales, Fabaceae) sources of qualitative genetic resistance to Asian soybean rust caused by Phakopsora pachyrhizi (Uredinales, Phakopsoraceae)
Pierozzi, Pedro Henrique Braga;Ribeiro, Aliny Simony;Moreira, José Ubirajara Vieira;Laperuta, Larissa Di Cássia;Rachid, Breno Francovig;Lima, Wilmar Ferreira;Arias, Carlos Alberto Arrabal;Oliveira, Marcelo Fernandes de;Toledo, José Francisco Ferraz de;
Genetics and Molecular Biology , 2008, DOI: 10.1590/S1415-47572008000300018
Abstract: asian soybean rust (asr), caused by the phytopathogenic fungi phakopsora pachyrhizi, has caused large reductions in soybean (glycine max) yield in most locations in brazil where it has occurred since it was first reported in may 2001. primary efforts to combat the disease involve the development of resistant cultivars, and four dominant major genes (rpp1, rpp2, rpp3 and rpp4) controlling resistance to asr have been reported in the literature. to develop new long-lasting soybean asr resistance genes, we used field experiments to assess asr leaf lesion type in 11 soybean genotypes (br01-18437, brs 184, brs 231, brs 232, brsgo chapad?es, dm 339, embrapa 48, pi 200487, pi 230970, pi 459025-a and pi 200526) and the 55 f2 generations derived from their biparental diallel crosses. the results indicated that pi 200487 and pi 200526 carry different dominant resistance major genes which are both different from rpp2 through rpp4. furthermore, resistance to asr in br01-18437 is controlled by a single recessive major gene, also different from rpp1 through rpp4 and different from the genes in pi 200487 and pi 200526.
Imunossupress?o com ciclofosfamida e fludarabina, com suporte de células tronco hematopoéticas autólogas CD-34+, para tratamento de esclerose sistêmica severa
von Mühlen, Carlos Alberto;Hinterholz, éverton Luís;Garicochea, Bernardo;Weingrill, Pedro;Barrios, Carlos;Fernandes, Mário Sérgio;Dahmer, Rosangela;Keiserman, Mauro W;Staub, Henrique Luiz;
Revista Brasileira de Reumatologia , 2004, DOI: 10.1590/S0482-50042004000200012
Abstract: immune ablation of t lymphocytes, key players in the physiopathogenic processes leading to autoimmune diseases, may arrest scleroderma progression even in some severely ill patients. high-dose chemotherapy followed by autologous stem cell reinfusion - sometimes named peripheral blood stem cell transplantation - has been an effective therapy for some autoimmune diseases, including scleroderma. in this paper the authors present a patient with the diffuse form of scleroderma who received immunosuppression with cyclophosphamide 0.5 g/m2 and fludarabine followed by infusion of autologous cd-34+ cells without t lymphocyte purging. this patient was followed up with cutaneous score measures, imaging and laboratory tests, as well as a well-being questionnaire. after transplantation there were major positive responses on skin and gastrointestinal tract, with cessation of diarrhea and malabsorption syndrome. these clinical improvements did not last past 6 months. we observed transitory stem cell transfusion reaction and localized herpes zoster. the patient died 12 months after the procedure due to aspirative pneumonia and gastrointestinal complications. the immunosuppressive regimen, and not the autologous stem cell transplantation, could have been responsible for the observed transitory patient improvement.
O relacionamento entre pessoas e serpentes no leste de Minas Gerais, sudeste do Brasil
Moura, Mário Ribeiro de;Costa, Henrique Caldeira;S?o-Pedro, Vinícius de Avelar;Fernandes, Vitor Dias;Feio, Renato Neves;
Biota Neotropica , 2010, DOI: 10.1590/S1676-06032010000400018
Abstract: the popular knowledge about snakes, including the practices adopted in cases of snakebite, was analysed in this ethnozoological study performed in araponga region and vicinities of serra do brigadeiro (brigadeiro mountain range), atlantic forest of minas gerais state, southeastern brazil. between august and november 2008, interviews were conducted with 50 residents of rural areas of araponga, and 20 employees of the serra do brigadeiro state park (pesb). in relation to social and cultural profile, these two groups differed only on the level of education (higher among the park staff), with the same distributions for age and religion. there was also a lower level of education among older individuals, a possible reflection of improvements in the social conditions in that region, which would have provided greater access to schools in recent decades. in general, both groups demonstrated adequate knowledge about prevention and procedures in cases of snakebite (78.2% reported seeking medical attention in case of snakebite). the use of folk medicine for treatment of snakebite proved to be a practice falling into disuse, reported by approximately 21% of respondents. most respondents (57.14%) said they did not know the difference between a poisonous and a non-poisonous snake, and 66.67% showed adequate knowledge of the season when snake encounters are more likely to happen. the "araponga" group was more hostile concerning to possible encounters with snakes, with 43% of people saying they would kill the animal, against 5% in the "pesb" group. the educational level of the respondents was decisive in determining the kind of attitude taken against snakes, and those with higher levels of education showed to be the less hostile ones. people with lower educational levels were more likely to consider all snakes as dangerous, and they also proved to be more hostile to these animals. more contact with scientific and environmental education activities seems to have been decisive for the
Germination of cotton cultivar seeds under water stress induced by polyethyleneglycol-6000
Meneses, Carlos Henrique Salvino Gadelha;Bruno, Riselane de Lucena Alcantara;Fernandes, Pedro Dantas;Pereira, Walter Esfrain;Lima, Leonardo Henrique Guedes de Morais;Lima, Marleide Magalh?es de Andrade;Vidal, Márcia Soares;
Scientia Agricola , 2011, DOI: 10.1590/S0103-90162011000200001
Abstract: the physiological quality of cotton cultivar seeds (gossypium hirsutum var. latifolium l.) was evaluated in laboratory by the simulation of water potentials with polyethyleneglycol-6000 (0.0; -0.2; -0.4; -0.6; -0.8 and -1.0 mpa), at 25oc using germitest paper as substrate. a completely randomized design in a 4 × 6 factorial scheme with four replications of 50 seeds each was used. the studied variables were: germination percentage, first count of germination, germination velocity index, accelerated aging in water, electrical conductivity, humidity, vigor classification, radicle length and radicle/shoot length ratio. the effect of water stress on seed viability and on plantlet vigor was severe at potentials below -0.4 mpa. the 'cnpa 187 8h' cultivar was the least sensitive to the tested osmotic potentials, both in terms of germination and of vigor. the 'brs-201' cultivar was mostly affected by the viability and vigor tests under water deficit conditions. differential viability and vigor between cultivars were observed under the water stress levels.
Nutri??o mineral de hortali?as. XXI. Efeito da omiss?o dos macronutrientes no crescimento e na composi??o química do piment?o (Capsicum annuum, L., var. Avelar)
Fernandes, Pedro Dantas;Haag, Henrique Paulo;
Anais da Escola Superior de Agricultura Luiz de Queiroz , 1972, DOI: 10.1590/S0071-12761972000100016
Abstract: the present work was carried out in order to study: a) the effect of omission and presence of the macronutrients on the growth of the plants; b) deficiency symptons of the macronutrients; c) the effect of the deficiency of each macronutrient on the chemical composition of the plants. young sweet pepper plants of variety avelar, were grown in pots containing pure quartz. twice a day, they were irrigated by percolation with nutrient solution. the treatments were: complete solution and deficient solutions, in which each one of the macronutrient was omitted (hoagland & arnon, 1950). when the malnutrition symptons appeared, the plants were harvested and divided into: roots, inferior and superior stalks, inferior and superior leaves, new and old fruits. the dry matter was analysed chemically. conclusions: 1) symptons of malnutrition are observed for n, p, k, ca, mg and s; 2) the symptons of deficiencies of k and mg appear on the new leaves; 3) this variety is resistent to blossom-androt; 4) plants grown in n and ca deficient solutions, show the largest reduction in development, compared to growth of normal plants; 5) the height of the plants is not affected by the omission of sulphur; 6) there's no reduction of the number of leaves on plants deficient in mg; 7) the nutrient content expressed in porcentages in the ripened leaves of plants cultivated under normal nutrition conditions and under deficient conditions, expressed in confidence interval at 5% level, are:
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