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Search Results: 1 - 10 of 22946 matches for " Pedro Enrique;Chamone "
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Triagem para o tratamento ambulatorial da neutropenia febril
Bellesso, Marcelo;Costa, Silvia Figueiredo;Chamone, Dalton Alencar Fischer;Llacer, Pedro Enrique Dorlhiac;
Revista Brasileira de Hematologia e Hemoterapia , 2010, DOI: 10.1590/S1516-84842010000500014
Abstract: febrile neutropenia is a frequent and potentially fatal adverse event of chemotherapy. nowadays, febrile neutropenia is considered an emergency and it is known that prompt infusion of antibiotics decreases mortality. several studies demonstrated that febrile neutropenia is a heterogeneous group of diseases and that factors such as outpatient status, no hypotension, no dehydration, no chronic obstructive pulmonary disease, no symptoms, no previous fungal infection and age < 60 years are protective factors against serious complications as demonstrated by the multinational association for supportive care in cancer (mascc). these data show that outpatient treatment and early discharge is safer and much research has shown lower costs for outpatient treatment in low-risk patients with febrile neutropenia. the aim of this work is to review and discuss tools (in particular the mascc index) for safe screening of febrile neutropenia for outpatient treatment in addition to demonstrate results of research.
Comparison of catheter-related infection risk in two different long-term venous devices in adult hematology-oncology patients
Pracchia, Luís Fernando;Dias, Lúcia Cristina Santos;Dorlhiac-Llacer, Pedro Enrique;Chamone, Dalton de Alencar Fisher;
Revista do Hospital das Clínicas , 2004, DOI: 10.1590/S0041-87812004000500012
Abstract: purpose: infection is the leading complication of long-term central venous catheters, and its incidence may vary according to catheter type. the objective of this study was to compare the frequency and probability of infection between two types of long-term intravenous devices. methods: retrospective study in 96 onco-hematology patients with partially implanted catheters (n = 55) or completely implanted ones (n = 42). demographic data and catheter care were similar in both groups. infection incidence and infection-free survival were used for the comparison of the two devices. results: in a median follow-up time of 210 days, the catheter-related infection incidence was 0.2102/100 catheter-days for the partially implanted devices and 0.0045/100 catheter-days for the completely implanted devices; the infection incidence rate was 46.7 (ci 95% = 6.2 to 348.8). the 1-year first infection-free survival ratio was 45% versus 97%, and the 1-year removal due to infection-free survival ratio was 42% versus 97% for partially and totally implanted catheters, respectively (p <.001 for both comparisons). conclusion: in the present study, the infection risk was lower in completely implanted devices than in partially implanted ones.
Aspergillary bronchopneumonia: an unusual cause of atelectasis and asphyxia in a leukemic patient
Velloso, Elvira Deolinda Rodrigues Pereira;Martinez, Gracia Aparecida;Dorlhiac-Llacer, Pedro Enrique;Chamone, Dalton Alencar Fischer;
Sao Paulo Medical Journal , 1994, DOI: 10.1590/S1516-31801994000400004
Abstract: a 22-year-old man in his first relapse of t-acute lymphoblastic leukemia developed fever and a pulmonary infiltrate after 23 days of granulocytopenia. although having been under amphotericin b for 10 days, productive purulent cough ensued, with right lobe atelectasis and acute ventilatory failure that resolved after the elimination of a thick gelatinous bronchial plug. sputum cultures yielded candida albicans and staphylococcus epidermidis, and microscopic examination of the sputum plug disclosed aspergillus hyphae. the patient died 9 days after, of a disseminated aspergillus infection, confirmed by necropsy.
The Use of Imatinib Mesylate as a Lifesaving Treatment of Chronic Myeloid Leukemia Relapse after Bone Marrow Transplantation
Monika Conchon,Sabri S. Sanabani,Israel Bendit,Carla Luana Dinardo,Lucia Dias,Dalton de Alencar Fischer Chamone,Pedro Enrique Dorlhiac-Llacer,Frederico Luiz Dulley
Journal of Transplantation , 2009, DOI: 10.1155/2009/357093
Abstract: We describe the response of imatinib as lifesaving treatment of chronic myeloid leukemia (CML) relapse in seven patients who underwent allogeneic bone marrow transplantation (alloBMT) at our institution over a period of 4 years. Retrospective analysis of their medical records revealed that a mean age at transplant was 45.2 years. The median time to diagnosis was 7.4 years after transplant. At relapse, four, two, and one patients were classified as having hematologic, major molecular, and cytogenetic relapse, respectively. At imatinib initiation, five had CML in a chronic phase, while one patient was diagnosed as having accelerated phase and blast crisis. All these patients could be evaluated for the therapeutic efficacy. At a mean of follow-up of 1.9 years of therapy, all evaluable patients achieved major molecular response without compromising safety. Consistent with available data, our results indicate that imatinib is safe and effective treatment option for patients with relapse after BMT.
Hemolytic disease of the newborn due to anti-U
Novaretti, Marcia Cristina Zago;Jens, Eduardo;Pagliarini, Thiago;Bonifácio, Silvia Le?o;Dorlhiac-Llacer, Pedro Enrique;Chamone, Dalton de Alencar Fischer;
Revista do Hospital das Clínicas , 2003, DOI: 10.1590/S0041-87812003000600006
Abstract: anti-u is a rare red blood cell alloantibody that has been found exclusively in blacks. it can cause hemolytic disease of the newborn and hemolytic transfusion reactions. we describe the case of a female newborn presenting a strongly positive direct antiglobulin test due to an igg antibody in cord blood. anti-u was recovered from cord blood using acid eluate technique. her mother presented positive screening of antibodies with anti-u identified at delivery. it was of igg1 and igg3 subclasses and showed a titer of 32. monocyte monolayer assay showed moderate interaction of fc receptors with maternal serum with a positive result (3.1%). the newborn was treated only with 48 hours of phototherapy for mild hemolytic disease. she recovered well and was discharged on the 4th day of life. we conclude that whenever an antibody against a high frequency erythrocyte antigen is identified in brown and black pregnant women, anti-u must be investigated.
El síndrome metabólico: un alto riesgo para individuos sedentarios
Soca,Pedro Enrique Miguel;
ACIMED , 2009,
Abstract: the metabolic syndrome comprises a group of ischemic cardiopaties risk factors and the type 2 mellitus diabetes. it is frequently associated to obesity and sedentary lifestyle. the characteristics of this syndrome are central obesity, atherogenic dyslipidemia, high figures of arterial blood pressure, insulin resistance, trend to a low grade inflammation and a prothombotic state. it is treated mainly with changes in life style, healthy diet, physical exercises, and elimination of toxic habits. the comorbidities are treated with medications. the fight against sedentary habits is an important part of its treatment.
Dislipidemias
Miguel Soca,Pedro Enrique;
ACIMED , 2009,
Abstract: the increase of the lipids in blood or dyslipidemias, mainly of the cholesterol and the triglycerides, it is a factor of atherosclerosis risk and cardiovascular illnesses. they are classified in primary or genetic and secondary. they are diagnosed with the determination of the cholesterolemia, trigliceridemia or both, besides the serum lipoproteins like high density lipoprotein or hdl and low density lipoprotein or ldl. it treatment consist in principle to changes in the lifestyles with healthy diets, physical exercises and elimination of the toxic habits. the main used medications are the statins, secuestrants and the fibrates.
Consideraciones sobre la inapetencia infantil y la adopción de hábitos alimentarios saludables
DUCUARA MORA,PEDRO ENRIQUE;
CES Medicina , 2011,
Abstract: to adopt healthy eating styles requires a process of teaching which involves stimulus and the examples that might generate parents and other caregivers of children, and thus, prevent inadequate food consumption and improve the acceptance of a variety of food products when these are introduced into the infant diet. it is conceived as a reasonable alternative for the adoption of healthy eating behavior begin to educate and encourage adequate food since childhood, even when the fetus is still in the womb through the mother's proper alimentation. the sensations of hunger and satiety are influenced by physiological mechanisms mediated by hormones and nervous system structures, as well as genetic factors that influence the expression of these molecular elements involved in the stimulation of the senses. in addition, nutrients and other food items, behaviors and attitudes of the family and the environment in which the individual is to be able to determine the eating patterns of children. eating behavior is a condition that is influenced by internal and external situations the individual and some of them can manage to achieve the acquisition of healthy eating habits in children. in this sense, the family and especially mothers are the once to determine the influence on the behavior and food consumption in children. for this article, we conducted a systematic review is not primarily employing electronic database isi web of knowledge.
El síndrome metabólico: un alto riesgo para individuos sedentarios The metabolic syndrome: a high risk for sedentary persons
Pedro Enrique Miguel Soca
ACIMED , 2009,
Abstract: El síndrome metabólico comprende un conjunto de factores de riesgo de cardiopatía isquémica y diabetes mellitus tipo 2. Se asocia con frecuencia a la obesidad y al sedentarismo. Los rasgos característicos del síndrome son la obesidad central, la dislipidemia aterógena, altas cifras de presión arterial, la resistencia a la insulina, una tendencia a la inflamación de bajo grado y un estado protrombótico. Se trata principalmente con cambios en el estilo de vida: dietas sanas, ejercicios físicos y eliminación de los hábitos tóxicos. Las comorbilidades asociadas se tratan enérgicamente con fármacos. El combate al sedentarismo es un pilar de su terapéutica. The metabolic syndrome comprises a group of ischemic cardiopaties risk factors and the type 2 mellitus diabetes. It is frequently associated to obesity and sedentary lifestyle. The characteristics of this syndrome are central obesity, atherogenic dyslipidemia, high figures of arterial blood pressure, insulin resistance, trend to a low grade inflammation and a prothombotic state. It is treated mainly with changes in life style, healthy diet, physical exercises, and elimination of toxic habits. The comorbidities are treated with medications. The fight against sedentary habits is an important part of its treatment.
Dislipidemias Dyslipidemias
Pedro Enrique Miguel Soca
ACIMED , 2009,
Abstract: El aumento de los lípidos en sangre o dislipidemias, sobre todo del colesterol y los triglicéridos, es un factor de riesgo de aterosclerosis y enfermedades cardiovasculares. Se clasifican en primarias o genéticas y secundarias. Se diagnostican con la determinación de la colesterolemia, trigliceridemia o ambas, además de las lipoproteínas séricas, como las lipoproteínas de alta densidad o HDL, y de baja densidad o LDL. Se tratan en principio con cambios en los estilos de vida, con dietas sanas, ejercicios físicos y eliminación de los hábitos tóxicos. Los principales medicamentos empleados son las estatinas, secuestrantes de ácidos biliares y los fibratos. The increase of the lipids in blood or dyslipidemias, mainly of the cholesterol and the triglycerides, it is a factor of atherosclerosis risk and cardiovascular illnesses. They are classified in primary or genetic and secondary. They are diagnosed with the determination of the cholesterolemia, trigliceridemia or both, besides the serum lipoproteins like high density lipoprotein or HDL and low density lipoprotein or LDL. It treatment consist in principle to changes in the lifestyles with healthy diets, physical exercises and elimination of the toxic habits. The main used medications are the statins, secuestrants and the fibrates.
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