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Search Results: 1 - 10 of 180780 matches for " Paula Jaqueline de;Bertolini "
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Efeitos do ultrassom terapêutico em modelo experimental de ciatalgia
Ciena, Adriano Policam;Cunha, Núbia Broetto;Moesch, Juliana;Mallmann, Juliana Schmatz;Carvalho, Alberito Rodrigo de;Moura, Paula Jaqueline de;Bertolini, Gladson Ricardo Flor;
Revista Brasileira de Medicina do Esporte , 2009, DOI: 10.1590/S1517-86922009000700004
Abstract: the sciatica possesses great general population prevalence, and its treatment tends to solve the nervous compression causes. physiotherapy aims to reduce the symptoms caused by compression. this study aimed to evaluate the effectiveness of therapeutic ultrasound on pain in animals subjected to sciatica experimental model. eighteen rats were used and they were divided in 3 groups: group sg (n=4) submitted to the sciatica and treated with the ultrasound off, group pug (n=7) submitted to the sciatica and treated with pulsed ultrasound 2 w/cm2 (satp; 0,4 - sata) and group cug (n=7) submitted to the sciatica and treated with continuous ultrasound (0,4 w/cm2). the sciatic nerve of the posterior right limb was exposed to the compression with catgut wire in 4 points. in the 3rd postoperative day, the indirect treatment was started (right inferior limb) for four days. in the 9th postoperative day, the direct treatment begins on the surgical procedure area for 5 serial days. the paw elevation time, during the march, of the animal was verified before and after the sciatica, at the 3rd, 6th, 9th and 13th postoperative day. the results demonstrated that the application of the therapeutic ultrasound reduced the pain with both treatments in pug and cug, and it has tended larger effectiveness in the pulsed form.
Ambient pH Controls Glycogen Levels by Regulating Glycogen Synthase Gene Expression in Neurospora crassa. New Insights into the pH Signaling Pathway
Fernanda Barbosa Cupertino, Fernanda Zanolli Freitas, Renato Magalh?es de Paula, Maria Célia Bertolini
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044258
Abstract: Glycogen is a polysaccharide widely distributed in microorganisms and animal cells and its metabolism is under intricate regulation. Its accumulation in a specific situation results from the balance between glycogen synthase and glycogen phosphorylase activities that control synthesis and degradation, respectively. These enzymes are highly regulated at transcriptional and post-translational levels. The existence of a DNA motif for the Aspergillus nidulans pH responsive transcription factor PacC in the promoter of the gene encoding glycogen synthase (gsn) in Neurospora crassa prompted us to investigate whether this transcription factor regulates glycogen accumulation. Transcription factors such as PacC in A. nidulans and Rim101p in Saccharomyces cerevisiae play a role in the signaling pathway that mediates adaptation to ambient pH by inducing the expression of alkaline genes and repressing acidic genes. We showed here that at pH 7.8 pacC was over-expressed and gsn was down-regulated in wild-type N. crassa coinciding with low glycogen accumulation. In the pacCKO strain the glycogen levels and gsn expression at alkaline pH were, respectively, similar to and higher than the wild-type strain at normal pH (5.8). These results characterize gsn as an acidic gene and suggest a regulatory role for PACC in gsn expression. The truncated recombinant protein, containing the DNA-binding domain specifically bound to a gsn DNA fragment containing the PacC motif. DNA-protein complexes were observed with extracts from cells grown at normal and alkaline pH and confirmed by ChIP-PCR analysis. The PACC present in these extracts showed equal molecular mass, indicating that the protein is already processed at normal pH, in contrast to A. nidulans. Together, these results show that the pH signaling pathway controls glycogen accumulation by regulating gsn expression and suggest the existence of a different mechanism for PACC activation in N. crassa.
Bioestimulante no vigor de sementes e plantulas de faveiro (Dimorphandra mollis Benth.)
Canesin, ?ngela;Martins, Jaqueline Maria Della Torre;Scalon, Silvana de Paula Quint?o;Masetto, Tathiana Elisa;
CERNE , 2012, DOI: 10.1590/S0104-77602012000200016
Abstract: this work aimed to verify the effects of biostimulant doses, applied through seeds, on faveiro (dimorphandra mollis benth.) seeds and seedlings vigor. seeds were previously sulfuric acid scarified in two consecutive years experiments. on 2006 august (first experiment) seeds were submitted on stimulate?: 0; 3.5; 7.0; 10.5 and 14 ml.0.5 kg-1 doses (first experiment); and seeds picked in august, 2007, were stimulate:0; 15; 20 and 25 ml.0.5kg-1 of seeds treated (second experiment). after the biostimulant treatment seeds were sowed in cells trays containing 1:1 (v:v) distroferric red latosol + plantmax?. the effect of different stimulate? doses on dimorphandra mollis seeds collected in different years were evaluated on the emergency percentage, speed emergency index, root length, aerial part height and dry seedling weight. it was conducted on entirely casualized with four repetitions of 25 seeds each treatment. the 14 ml (2006 lot) and 15 ml (2007 lot) 0.5kg-1 of seeds doses provided larger percentage (50% and 66%, respectively) and speed emergency indexes (0.67 and 0.9 respectively). the 20 ml.0.5kg-1 of seeds dose treatment favored the aerial part length, but it didn't influenced the other dimorphandra mollis seedlings vigor indexes.
Pathophysiology of acute meningitis caused by Streptococcus pneumoniae and adjunctive therapy approaches
Barichello, Tatiana;Generoso, Jaqueline S.;Collodel, Allan;Moreira, Ana Paula;Almeida, Sérgio Monteiro de;
Arquivos de Neuro-Psiquiatria , 2012, DOI: 10.1590/S0004-282X2012000500011
Abstract: pneumococcal meningitis is a life-threatening disease characterized by an acute purulent infection affecting piamater, arachnoid and the subarachnoid space. the intense inflammatory host's response is potentially fatal and contributes to the neurological sequelae. streptococcus pneumoniae colonizes the nasopharynx, followed by bacteremia, microbial invasion and blood-brain barrier traversal. s. pneumoniae is recognized by antigen-presenting cells through the binding of toll-like receptors inducing the activation of factor nuclear kappa b or mitogen-activated protein kinase pathways and subsequent up-regulation of lymphocyte populations and expression of numerous proteins involved in inflammation and immune response. many brain cells can produce cytokines, chemokines and others pro-inflammatory molecules in response to bacteria stimuli, as consequence, polymorphonuclear are attracted, activated and released in large amounts of superoxide anion and nitric oxide, leading to the peroxynitrite formation, generating oxidative stress. this cascade leads to lipid peroxidation, mitochondrial damage, blood-brain barrier breakdown contributing to cell injury during pneumococcal meningitis.
Biostimulant on faveiro (Dimorphandra mollis Benth.) seeds and seedling vigor
?ngela Canesin,Jaqueline Maria Della Torre Martins,Silvana de Paula Quint?o Scalon,Tathiana Elisa Masetto
CERNE , 2012,
Abstract: This work aimed to verify the effects of biostimulant doses, applied through seeds, on faveiro (Dimorphandra mollis Benth.) seeds and seedlings vigor. Seeds were previously sulfuric acid scarified in two consecutive years experiments. On 2006 August (first experiment) seeds were submitted on Stimulate : 0; 3.5; 7.0; 10.5 and 14 mL.0.5 Kg-1 doses (first experiment); and seeds picked in August, 2007, were Stimulate:0; 15; 20 and 25 mL.0.5Kg-1 of seeds treated (second experiment). After the biostimulant treatment seeds were sowed in cells trays containing 1:1 (v:v) distroferric red latosol + plantmax . The effect of different Stimulate doses on Dimorphandra mollis seeds collected in different years were evaluated on the emergency percentage, speed emergency index, root length, aerial part height and dry seedling weight. It was conducted on entirely casualized with four repetitions of 25 seeds each treatment. The 14 mL (2006 lot) and 15 mL (2007 lot) 0.5Kg-1 of seeds doses provided larger percentage (50% and 66%, respectively) and speed emergency indexes (0.67 and 0.9 respectively). The 20 mL.0.5Kg-1 of seeds dose treatment favored the aerial part length, but it didn't influenced the other Dimorphandra mollis seedlings vigor indexes.
Estudo do mirtilo (Vaccinium ashei Reade) no processamento de produtos alimentícios
Moraes, Jaqueline Oliveira de;Pertuzatti, Paula Becker;Corrêa, Fernanda Villar;Salas-Mellado, Myriam de Las Mercedes;
Ciência e Tecnologia de Alimentos , 2007, DOI: 10.1590/S0101-20612007000500003
Abstract: rabbiteye blueberry is favourable consumption wise due to its color and to the high natural antioxidant substance content such as phenolic compounds that are mainly anthocyanins. the fruit is already cultivated in the brazil, however it does not exist as an industrialized product. the aim of the present work is to measure phenolic compounds, antioxidant capacity and to characterize different varieties of rabbiteye blueberry (vaccinium ashei reade) as well as to develop products and evaluate them under the same parameters. the fruit was donated by embrapa clima temperado, pelotas (rs), the processed products were nectar and a cereal bar with rabbiteye blueberry raisins.
Freqüência de diabetes mellitus e hiperglicemia em mulheres chagásicas e n o-chagásicas
Santos Vitorino Modesto dos,Cunha Selma Freire de Carvalho da,Teixeira Vicente de Paula Antunes,Monteiro Jaqueline Pontes
Revista da Sociedade Brasileira de Medicina Tropical , 1999,
Abstract: Estudo retrospectivo de 647 mulheres com idade340 anos, atendidas no Hospital-Escola da FMTM, Uberaba-MG. As três sorologias para a doen a de Chagas foram negativas nas controles (n = 285) e positivas nas chagásicas (n = 362), que foram classificadas nas formas indeterminada (n = 125), megas (n = 58) e cardíaca (n = 179). Diabetes mellitus foi definido por duas glicemias em jejum3140mg/dl e hiperglicemia por glicemia em jejum > 110mg/dl. Os grupos foram comparados pelos testes do c2, análise de variancia, "t" de Student, Kruskal-Wallis e Mann-Whitney, considerando-se significativo p < 0,05. chagásicas e controles estavam pareadas quanto à idade, o índice de massa corporal e a cor. Diabetes mellitus foi mais freqüente na forma cardíaca (15,1%), comparada com as controles (7,4%), megas (7,4%) e assintomáticas (5,6%), o mesmo ocorrendo com a hiperglicemia (37,4%, 26,7%, 25,9% e 27,2%, respectivamente), achados que est o de acordo com possível desnerva o parassimpática causada pelo Trypanosoma cruzi e conseqüente predomínio da atividade simpática.
HEADACHE IN CHAGASIC WOMEN
SANTOS Vitorino Modesto dos,CUNHA Selma Freire de Carvalho da,TEIXEIRA Vicente de Paula Antunes,MONTEIRO Jaqueline Pontes
Revista do Instituto de Medicina Tropical de S?o Paulo , 1999,
Abstract: The aim of this study was to compare the frequency of headache between Chagasic and Non-chagasic women. The cross-sectional study comprised 647 female 340 years old, Chagasic (n = 362) and Controls (n = 285) at a Brazilian University Hospital. Chagasic were classified as Cardiac (n = 179), Megas (n = 58) or Indeterminate (n = 125) clinical forms. Headache was ascertained according to Headache International Society diagnostic criteria. The age (57.0 ± 11.3 versus 57.3 ± 10.4 years), and the percentage of white women (75.8% versus 77.1%) were similar between Chagasic and Controls, respectively. Headache was more prevalent among Chagasic (32.9%) than Controls (16.1%), mainly in Cardiac form (odds ratio, 2.41; 95% confidence interval, 1.38-4.23), phenomenon possibly related to parasympathetic denervation and cerebral vessels changes.
Ganho de extensibilidade dos músculos isquiotibiais comparando o alongamento estático associado ou n?o à crioterapia
Busarello, Fernanda de Oliveira;Souza, Francieli Tibes de;Paula, Grazieli Francine de;Vieira, Lizyana;Nakayama, Gustavo Kiyosen;Bertolini, Gladson Ricardo Flor;
Fisioterapia em Movimento , 2011, DOI: 10.1590/S0103-51502011000200006
Abstract: introduction: cryotherapy is indicated to decrease the discomfort during the sessions of stretching and provide better results in the gain of extensibility. objective: study's objective was to verify the gain extensibility of ham-string muscles, comparing the static stretching with static stretching associated with cryotherapy. materials and methods: twenty subjects participated of the study, aged between 18 and 25 years, divided equally in two groups, considering that both performed stretching and stretching associated with cryotherapy. it has been used ice packs on the back of the thigh for 15 minutes. then, it has been realized the application of static stretching of hamstrings, in two sets of 30 seconds each. results: it has been found significant differences in the extensibility of hamstring muscles in both groups, but there were no significant differences in the extensibility of hamstring muscles when compared static stretching with static stretching associated with cryotherapy. conclusion: there was an immediate increase of the extensibility of hamstring muscles. however, the use of cryotherapy was not effective for gain of extensibility.
Varia??o de temperatura do músculo quadríceps femoral exposto a duas modalidades de crioterapia por meio de termografia
Carvalho, Alberito Rodrigo de;Medeiros, Daiane Lazzeri de;Souza, Francieli Tibes de;Paula, Grazieli Francine de;Barbosa, Patrícia Mantovani;Vasconcellos, Paula Renata Olegini;Buzanello, Márcia Rosangela;Bertolini, Gladson Ricardo Flor;
Revista Brasileira de Medicina do Esporte , 2012, DOI: 10.1590/S1517-86922012000200009
Abstract: introduction: cryotherapy is any form of therapeutic application of cold which decreases the temperature of tissues. objective: to compare the variations in surface temperature of the quadriceps muscle at three different times when exposed to two forms of cryotherapy: ice bags or bags containing a mixture of ice and water. material and methods: the study involved 18 subjects, aged between 18 and 25 years, of both sexes. in each volunteer, ice cryotherapy on the left thigh and a mixture of ice and water on the right thigh was simultaneously applied for 15 minutes to the quadriceps femoris region. the temperature was measured by a thermograph and the following moments were recorded : before cryotherapy, immediately and 5 and 30 minutes after removal of the modality of cryotherapy. results: both cryotherapy methods were effective to decrease the temperature of the quadriceps and the mixture of ice and water was able to induce a lower temperature compared to the modality which used ice only. the cooling for both modalities lasted for at least 15 minutes after the removal of ice and surface temperature had been restored at pre application 30 minutes after removal. conclusion: both methods promoted a reduction in temperature that lasted at least 15 minutes, and 30 minutes after the withdrawal the temperature was reestablished to normal levels. however, the mixture of ice and water produced cooling more remarkable than the ice alone.
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