oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 69 )

2018 ( 88 )

2017 ( 82 )

2016 ( 73 )

Custom range...

Search Results: 1 - 10 of 23650 matches for " Paul Macaire Ossou-Nguiet "
All listed articles are free for downloading (OA Articles)
Page 1 /23650
Display every page Item
Anterior Cerebral Infarction by Fronto-Basal Meningioma  [PDF]
Paul Macaire Ossou-Nguiet, Dieu Donné Gnonlonfoun, Karen Obondzo-Aloba, Hugues Brieux Ekouélé-Mbaki, Gilbert Fabrice Otiobanda
Neuroscience & Medicine (NM) , 2013, DOI: 10.4236/nm.2013.44040
Abstract:

The association between stroke and meningioma is rarely reported in the data. In most etiology classification, there is no compressive cause. The association between meningioma and stroke is increasingly reported. We report a case of 52-year-old woman, previously healthy, presented with sudden right hemiplegia with some transient mood disorders. The CT-scan revealed acute left anterior cerebral artery infarction associated with fronto-basale meningioma infiltrating both anterior cerebral arteries. She was treated by corticosteroid and rehabilitation, with partial recovery. No stroke prevention was used before surgical treatment.

Hypertension and intracerebral hemorrhage in Brazzaville  [PDF]
Thierry Raoul Gombet, Paul Macaire Ossou-Nguiet, Thibaut Naibe Gankama, Bertrand Fikahem Ellenga-Mbolla, Gilbert Fabrice Otiobanda, Karen Obondzo-Aloba, Benjamin Longo-Mbenza
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.39083
Abstract:

Hypertension is not only an important risk factor, but also an important cause of spontaneous intracerebral hemorrhage. Its high prevalence in Africa reflects a high incidence of cerebral hemorrhage ranging from 30% to 60% against 10% to 20% in industrialized countries. The aim of our study was to determine the role of hypertension before the onset of intracerebral hemorrhage and its variations during the first three months. This was a longitudinal study conducted at the University Hospital of Brazzaville from 1st January to 31st August 2012 with all patients admitted for intracerebral hemorrhage. Patients with subarachnoid or pure intraventricular hemorrhage were excluded. The study variables were: history of hypertension, knowledge of its history, treatment, blood pressure on admission and during the first 3 months and the relationship between blood pressure and evolution. Statistical analysis was performed using the software SPSSS 16.1. The significance level was set at p < 0.05. During the study 261 patients were hospitalized for stroke, of which 82 (31.42%) were for intracerebral hemorrhage. The mean age was 55 ± 11 years and sex ratio of 2 men:1 woman. Hypertension was found in 80.5% of cases, of which 65.2% had known hypertension, but 82.6% had discontinued treatment. The mean systolic blood pressure was 194 ± 41 mm Hg and diastolic 104 ± 20 mm Hg. The location was deep in 85.71%. The normalization of blood

pressure was obtained from the second week. After adjusting for confounders using logistic analysis, only uncontrolled hypertension was associated significantly and independently associated with a higher mortality rate (p = 0.042).

 

Post-Stroke Cognitive Disorders and Associated Factors in French Speaking West Africa, Benin Case  [PDF]
Dieu Donné Gnonlonfoun, Paul Macaire Ossou-Nguiet, Lansana Laho Diallo, Constant Adjien, Isaac Avlessi, Gérard Goudjinou, Octave Houannou, Dismand Houinato, Gilbert Dossou Avode
Neuroscience & Medicine (NM) , 2014, DOI: 10.4236/nm.2014.51006
Abstract:

Introduction: Cognitive disorders frequency arising after a cardio-cerebral vascular disease (stroke) is currently on the rise due to the ageing population and the increase in the number of survivors after stroke occurrence. Objective: Determining post-stroke cognitive decline and identifying associated factors. Method: It consists in a cross-sectional, prospective, descriptive and analytical study which was conducted from April 1 to August 31, 2013 in the Neurology Department of CNHU-HKM in Cotonou. The study involved 100 patients who have known stroke for at least the past 6 months and were all admitted and discharged later on. The disease survivors were re-contacted and examined again at home or at hospital. The cognitive decline (CD) was estimated by using a modified and adapted MMSE to suit our cultural era. Results: All patients were aged 58.9 years ± 13.6 years. Sex-ratio was 1.4. Cognitive decline frequency was 20%. Post-stroke cognitive decline frequency per sex was 11.6% and 8.4% respectively for females and males. Ischemia stroke patients had a higher cognitive decline (22.5%). 58.3% had severe CD. Moreover the CD frequency increased with time, from 16.7% in a year to 50% in 3 years. Total MMSE varied from 6 to 23 with 21 as median. From the unvaried analysis, the presence of sphincter disorders (1.26 [0.35-4.59], p = 0.004), consciousness disorders (15.67 [1.46-168], p

Stroke after Hospitalization: Assessment of Functional Prognosis through Disability and Dependency in CNHU-HKM, Cotonou, Benin  [PDF]
Dieu Donné Gnonlonfoun, Paul Macaire Ossou-Nguiet, Lansana Laho Diallo, Constant Adjien, Isaac Avlessi, Octave Houannou, Gérald Goudjinou, Jocelyn Acakpo, Dismand Houinato, Dossou Gilbert Avode
Neuroscience & Medicine (NM) , 2014, DOI: 10.4236/nm.2014.53017
Abstract:

Introduction: Stroke results in severe disability, with impacts that are sometimes socially, emotionally or professionally dramatic and also dramatic for the cost involved in care and treatment. Objective: Assessing the functional prognosis after hospitalization and identifying associated factors. Method: It consisted in a cross-sectional, prospective, descriptive and analytical study that was conducted from April 1 to August 31, 2013 in the Neurology Department of CNHU-HKM in Cotonou. It involved 100 patients who have known stroke for at least 6 months and were all admitted and discharged later on. The disease survivors were re-contacted and examined again at home or at hospital. Disability and dependency were then measured respectively with the Rankin score and Barthel index. The STATA/IC11.0 statistical software was used as the basis for data analysis. Unvaried and multi-varied analyzes helped to identify associated factors. Results: The overall disability and dependency rates were respectively 69% and 57.7%. And the highest rate of disability (38.8%) was observed between 50 and 60 years old. However, dependency prevalence was higher in subjects above 70 years old (37.3%). Regarding gender, the prevalence of disability was 59.2% in men and rather 41.5% in women. Predictors of disability and dependency were paralysis on admission (IC95% = 0.26 [0.77 - 0.92]; p = 0.036), obesity (IC95% = 0.26 [0.77 - 0.92]; p = 0.012) and monthly income lower than 70$US (IC95% = 0.05 [0.01 - 0.56]; p = 0.015). Conclusion: This study enabled us to assess the functional outcome of patients once discharged. The significance of motor deficit on stroke occurrence, obesity and the low monthly income were factors of poor functional prognosis.

Prevalence of Dementia and Its Associated Factors in Cotonou Teaching Hospital, Benin  [PDF]
Dieu Donné Gnonlonfoun, Constant Adjien, Paul Macaire Ossou-Nguiet, Lansana Laho Diallo, Octave Houannou, Jocelyn Acakpo, Gérard Goudjinou, Dismand Houinato, Dossou Gilbert Avode
Advances in Alzheimer's Disease (AAD) , 2014, DOI: 10.4236/aad.2014.32010
Abstract: Introduction: Dementia constitutes a public health hazard in developing countries. There is little data in the sub-Saharan region of African especially in Benin. Objective: Determining dementia hospitalization prevalence and identifying its associated factors in CNHU-HKM, Cotonou. Method: It was a cross-sectional, prospective, descriptive and analytical research conducted from October 2012 to July 2013 in the neurology department; it involved 251 patients aged 50 and above. Dementia screening was conducted using a modified and adapted Mini Mental Scale Examination (MMSE). Dementia clinical and etiological diagnoses were respectively conducted based on DMS-IV and HACHINSKI criteria. Results: Patients were averagely aged 60.9 ± 8.1. Sex ratio (Male/Female) was 1.07. Dementia prevalence was 8.8%. This rate increased proportionally with age, from 5.3% with patients aged below 60 to 12.7% with patients aged above 60. Degenerative dementia was the most predominant type (50%). Following multi-varied analysis, smoking (RC = 6.05 [IC 95% = 1.26 - 29.38] p = 0.0001) and stroke past records (RC = 6.05 [IC 95% = 1.26 - 29.38] p = 0.001) revealed to be the factors associated with dementia. Conclusion: This research showed that dementia affects a significant part of the aging population in CNHU-HKM. It is imperative to combat its associated factors so as to defuse its prevalence.
Stroke: Medium and long-term mortality and associated factors in French-speaking West Africa, case of Benin  [PDF]
Dieu Donné Gnonlonfoun, Constant Adjien, Paul Macaire Ossou-Nguiet, Isaac Avlessi, Gérald Goudjinou, Octave Houannou, Jocelyn Acakpo, Dismand Houinato, Gilbert Dossou Avode
World Journal of Neuroscience (WJNS) , 2014, DOI: 10.4236/wjns.2014.41008
Abstract:

Introduction: Stroke is the leading cause of mortality and physical disability in sub-Saharan Africa. Objective: Determining medium-term and long-term mortality for stroke and identifying associated factors. Method: It consists in a cross-sectional, prospective, descriptive and analytical study that was conducted from April 1 to August 31, 2013 in the Neurology Department of CNHU-HKM in Cotonou. It involved patients who have known stroke for at least 6 months, and were all admitted and discharged later on. The disease survivors were re-contacted and examined again at home or at hospital. Then, the number of deceased was systematically recorded with precision of death time-limit. Results: The overall mortality rate was 29%. Mortality was higher with patients over 70 years with a frequency of 57.1%. The medium-term mortality rate was 25% against 4% for long-term. The average time-limit for death occurrence after the vascular incident was 7 months ± 6.4 months. Prognostic factors of mortality were: the age of the patient (IC95% = 7.73 [1.49 - 39.99], p = 0.015 ), marital status (IC95% = 0.27 [0.08 to 0.94], p = 0.039 ) and the presence of aphasia (IC95% = 5.52 [1.45 to 20.94 ], p = 0.012). Conclusion: Stroke mortality still remains significant, even after the patients have been discharged from hospital. A good psychological family support and efficient aphasia coverage are essential for its reduction.

Stroke in type 2 diabetes mellitus patients admitted to emergency unit in Central African country (Congo): Preliminary findings  [PDF]
Bertrand Fikahem Ellenga-Mbolla, Henri Germain Monabeka, Paul Macaire Ossou-Nguiet, Gilbert Fabrice Otiobanda, Kryste Chancel Mahoungou Guimbi, Thierry Raoul Gombet, Suzy-Gisèle Kimbally-Kaky, Benjamin Longo Mbenza
Journal of Diabetes Mellitus (JDM) , 2013, DOI: 10.4236/jdm.2013.34032
Abstract:

Background: The cardiovascular risk factors including type 2 diabetes mellitus (T2DM) are a public health problem in sub-Saharan Africa. The aim of this study is to determine the prevalence and factors associated with stroke in T2DM patients admitted to the emergency Unit in Brazzaville. Patients and Methods: This is the preliminary findings of a cross-sectional study including patients with T2DM, admitted in Emergency Unit of University Hospital of Brazzaville from January to April 2011. One hundred and seven patients were included. Sex ratio was 1.5. Results: The mean age was 60.3 ± 10.2 years (range 40 - 80 years). Stroke story was noted in 5 cases (4.6%). The main pathologies were metabolic complications (n = 51; 47.6%) and cardiovascular diseases (n = 36; 33.6%), dominated by stroke (17 cases). Epidemiological factors associated with stroke were high standard living (OR = 3, 95% CI: 1.02 - 8.9, p = 0.03), polypharmacy (OR = 3.7, 95% CI: 1.27 - 10.8, p = 0.01), previous hospitalization (OR = 3.1, 95% CI: 1.07 - 8.9, p = 0.03), and the absence of antiplatelet therapy (OR = 4.2, 95% CI 1.2 to 15, p = 0.03). Clinical associated factors were coma (OR = 3.3, 95% CI 1.14 to 9.6, p = 0.02) and the presence of severe hypertension (OR = 4, 95% CI: 1.2 - 12, p = 0.02). Finally, prognostic factors were the transfer in intensive care unit (OR = 9.8, 95% CI: 2.7 - 34, p < 0.001). Conclusion: The first cardiovascular complication in patients with T2DM admitted in emergency at University Hospital of Brazzaville is stroke. Primary prevention in high-risk patients is still inadequate.

Hypertension, diabetes mellitus, overweight and obesity in employees under health transition at the railways company in Congo-Brazzaville  [PDF]
Bertrand Fikahem Ellenga Mbolla, Thierry Raoul Alexis Gombet, Henri Germain Monabeka, Paul Macaire Ossou-Nguiet, Solange Flore Mongo-Ngamami, Christian Michel Kouala Landa, Suzy-Gisèle Kimbally-Kaky, Benjamin Longo-Mbenza
World Journal of Cardiovascular Diseases (WJCD) , 2014, DOI: 10.4236/wjcd.2014.42008
Abstract:

Background and Aim: Cardiovascular risk (CVR) factors, namely hypertension (HT), diabetes mellitus and obesity, are a public health problem in sub-Saharan Africa because of health transition. The additional effect of the social gradient within the railway companies in Congo-Brazzaville on high CVR is not yet established. The aim of this study was to determine the extent of hypertension, diabetes mellitus, overweight, and obesity and to identify the contributing factors of fatness and hypertension. Methods: This was a cross-sectional study conducted in April 2013. A simple random sample of 255 out of all 2550 workers from the railway companies of Congo was examined for epidemiological, clinical and biological variables. Results: Out of the study sample, 231 (90.6%), 79 (31%), and 52 (20.4%) were men, rural dwellers, and senior executives, respectively. The mean age was 45 ± 13 years (range 19 to 63 years). The rates of overweight, hypertension, obesity, and diabetes mellitus were 40.3% (n = 103), 29.4% (n = 75), 7.5% (n = 19), and 3.5% (n = 9), respectively. In univariate analysis, female sex (OR 2.7, 95% CI 1.13 - 6.45, p = 0.01), senior executive (OR 2.4; 95% CI: 1.3 - 4.5; p = 0.003) and physical inactivity (OR 2.5; 95% CI: 1.5 - 4.2; p < 0.001) were significantly associated with overweight. Female sex (OR 7.5, 95% CI: 2.6 - 21; p < 0.001) and senior executive (OR 3.17; 95% CI:

1.2 - 8.3) were also significantly associated with obesity. In logistic regression, overweight (OR = 4.8, 95% CI 2.8 - 11, p < 0.0001), and obesity (OR = 6.8, 95%CI 2.1 - 22, p = 0.01) were identified as the most important and independent determinants of hypertension. Conclusions: Fatness is emerging and it is the most contributing factor of hypertension among workers at the Congolese railway companies. There is also a significant interaction between non-modifiable factors (genetic: females and family history) and modifiable factors (inactivity, fatness) for higher risk of hypertension. Health promotion should be emphasized by
Excessive Alcohol Intake and Cigarette Smoking among Black Schoolchildren in a Central African City (Brazzaville, Congo)  [PDF]
Annie Rachel Okoko, Gaston Ekouya Bowassa, Bertrand Fikahem Ellenga Mbolla, Moyen Engoba, Paul Ossou-Nguiet, Suzy-Gisèle Kimbally-Kaky, Georges Marius Moyen
Open Journal of Pediatrics (OJPed) , 2017, DOI: 10.4236/ojped.2017.71003
Abstract: Objective: To determine the prevalence of excessive alcohol intake (EAI) and cigarette smoking (CS) in schoolchildren of Brazzaville. Methods: This cross sectional survey included a representative population of schoolchildren in Brazzaville (603 schoolchildren divided 325 girls and 278 boys). Results: The prevalence of EAI was 9% (n = 54). The mean age of EAI children was 16.2 ± 1.3 years (range: 13 - 18 years) vs 11.4 ± 3.4 years (range: 5 - 18 years) for no EAI children (p < 0.001). In logistic regression, the independents determinants of EAI were: age, alcoholism in parent, orphans, siblings, low social level. The receiving operative curve (ROC) of age and EAI shown a sensitivity of 74.1% and specificity of 85.1% for 15.5 years: area under curve (AUC) = 0.891 (95% IC: 0.86 - 0.92; p < 0.001). The prevalence of CS was 2.5% (n = 15). The mean age of smokers children was 15.9 ± 1.5 years (range: 13 - 18 years) vs 11.7 ± 3.6 years (range: 5 - 18 years) for no smokers children (p < 0.01). In logistic regression, the independents determinants of CS were: siblings, migration, orphans, male sex. The ROC of age and cigarette smoking shown a sensitivity of 73.3% and specificity of 73.6% (AUC: 0.839; 95% IC: 0.77 - 0.90; p = 0.035) for 14.5 years. Conclusion: Low social level, siblings, addictions in parents were correlate addictions in schoolchildren. It is necessary to prevent the acute and futures complications of this addiction in our children.
Impact of urinary tract and pulmonary infection on mortality after intracerebral hemorrhage in Brazzaville  [PDF]
P. M. Ossou-Nguiet, B. F. Ellenga-Mbolla, A. S. W. Odzebe, G. F. Otiobanda, T. N. Gankama, K. Obondzo-Aloba, T. R. Gombet
World Journal of Neuroscience (WJNS) , 2013, DOI: 10.4236/wjns.2013.34033
Abstract:

Objective: To evaluate the impact of urinary tract and pulmonary infection on mortality after cerebral hemorrhage. Method: We conducted at the University Hospital of Brazzaville, a cross-sectional study from January to August2012 inthe emergency department, neurology and intensive care unit. It included patients admitted for cerebral hemorrhage confirmed by CT-scan. A statistical analysis by logistic regression was carried out to evaluate the correlation between infection and death. Result: Among total of 261 patients for stroke, 82 admitted for cerebral hemorrhage (31.4%). The mean age was 55 ± 11 years (range 26 to 83 years). The sex ratio men/women was 1.7. Hypertension was the most important risk factor to 80.5%. The average intake in neurology time was 28 ± 13 hours. The average time for completion of the CT-scan was 2.4 ± 2 days. Thirty-eight (46.3%) patients had a fever linked to an infectious cause from the third day of hospitalization. The most frequent infectious complications were sepsis (n = 16%; 42%), pulmonary infection (n = 14%; 37%) and urinary tract infection (n = 8%; 21%). Specific mortality of infection was 31.7% (n = 26). The multivariate analysis showed a positive correlation between the occurrence of infection and mortality (p = 0.002), specifically between sepsis and mortality (p = 0.0004), and an association between the time of admission late in neurology and the occurrence of infectious complications (p = 0.0001). Conclusion: Infection is one of the dreaded complications of cerebral hemorrhage. It is often associated with delayed care in specialized areas, and is thereby a preventable cause of death.

Page 1 /23650
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.